Astrocytes show reduced support of motor neurons with aging that is accelerated in a rodent model of ALS

Neurobiology of Aging

Volumn 36, Issue 2, 2015, Pages 1130-1139

  Das, Melanie M ^a   Svendsen, Clive N ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

Aging; Amyotrophic lateral sclerosis; Astrocytes; Cellular senescence; Glial cell line derived neurotrophic factor; Interleukin 6; Superoxide dismutase 1

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; INTERLEUKIN 6; SUPEROXIDE DISMUTASE;

ADULT; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; BIOACCUMULATION; CELL AGING; CELL ASSAY; CELL SURVIVAL; CONTROLLED STUDY; FEMALE; MALE; MOTONEURON; NERVE CELL CULTURE; NERVE CELL NECROSIS; NEWBORN; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; RAT; SENESCENCE; UPREGULATION; AGING; ANIMAL; CELL CULTURE; DISEASE MODEL; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; PREGNANCY; SPRAGUE DAWLEY RAT;

AGING; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ASTROCYTES; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; INTERLEUKIN-6; MALE; MOTOR NEURONS; PREGNANCY; RATS, SPRAGUE-DAWLEY; SUPEROXIDE DISMUTASE;

EID: 84922930786     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2014.09.020     Document Type: Article

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