Phosphatase and tensin homologue/protein kinase B pathway linked to motor neuron survival in human superoxide dismutase 1-related amyotrophic lateral sclerosis

Brain

Volumn 134, Issue 2, 2011, Pages 506-517

  Kirby, Janine ^a   Ning, Ke ^a   Ferraiuolo, Laura ^a   Heath, Paul R ^a   Ismail, Azza ^a   Kuo, Su Wei ^a   Valori, Chiara F ^a   Cox, Laura ^a   Sharrack, Basil ^b   Wharton, Stephen B ^a   Ince, Paul G ^a   Shaw, Pamela J ^a   Azzouz, Mimoun ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b ROYAL HALLAMSHIRE HOSPITAL   (United Kingdom)

Author keywords

AKT; amyotrophic lateral sclerosis; PI3K; PTEN; SOD1

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; LENTIVIRUS VECTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROGRAMMED DEATH 1 RECEPTOR; PROTEIN KINASE B; PROTEIN KINASE B GAMMA; PROTEIN KINASE C; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG;

ADULT; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CASE REPORT; CELL CULTURE; CELL DEATH; CELL SURVIVAL; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE SILENCING; GENE TARGETING; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LASER CAPTURE MICRODISSECTION; MALE; MICROARRAY ANALYSIS; MOTONEURON; NERVE DEGENERATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SPINAL CORD MOTONEURON;

ADULT; AGED; AGED, 80 AND OVER; AMYOTROPHIC LATERAL SCLEROSIS; APOPTOSIS REGULATORY PROTEINS; CELL CULTURE TECHNIQUES; CELL LINE, TRANSFORMED; CELL SURVIVAL; FEMALE; GENE EXPRESSION PROFILING; GENETIC VECTORS; HUMANS; LENTIVIRUS; MALE; MIDDLE AGED; MOTOR NEURONS; MUTATION; NERVE DEGENERATION; PHOSPHATIDYLINOSITOL 3-KINASE; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION; SUPEROXIDE DISMUTASE;

EID: 79551690481     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awq345     Document Type: Article

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