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Volumn 36, Issue 3, 2016, Pages 483-502

Chronic Infection and Severe Asthma

Author keywords

Chlamydophila pneumoniae; Chronic infection; Macrolides; Microbiome; Mycoplasma pneumoniae; Severe asthma

Indexed keywords

MACROLIDE; ANTIINFECTIVE AGENT;

EID: 84976479928     PISSN: 08898561     EISSN: 15578607     Source Type: Journal    
DOI: 10.1016/j.iac.2016.03.010     Document Type: Review
Times cited : (27)

References (142)
  • 1
    • 0021674449 scopus 로고
    • Mycoplasma pneumoniae: acute illness, antibiotics, and subsequent pulmonary function
    • 1 Sabato, A.R., Martin, A.J., Marmion, B.P., et al. Mycoplasma pneumoniae: acute illness, antibiotics, and subsequent pulmonary function. Arch Dis Child 59:11 (1984), 1034–1037.
    • (1984) Arch Dis Child , vol.59 , Issue.11 , pp. 1034-1037
    • Sabato, A.R.1    Martin, A.J.2    Marmion, B.P.3
  • 2
    • 84923780557 scopus 로고    scopus 로고
    • Community-acquired pneumonia requiring hospitalization among U.S. children
    • 2 Jain, S., Williams, D.J., Arnold, S.R., et al. Community-acquired pneumonia requiring hospitalization among U.S. children. N Engl J Med 372:9 (2015), 835–845.
    • (2015) N Engl J Med , vol.372 , Issue.9 , pp. 835-845
    • Jain, S.1    Williams, D.J.2    Arnold, S.R.3
  • 3
    • 84987829258 scopus 로고    scopus 로고
    • Novel aspects on the pathogenesis of Mycoplasma pneumoniae pneumonia and therapeutic implications
    • 3 Saraya, T., Kurai, D., Nakagaki, K., et al. Novel aspects on the pathogenesis of Mycoplasma pneumoniae pneumonia and therapeutic implications. Front Microbiol, 5, 2014, 410.
    • (2014) Front Microbiol , vol.5 , pp. 410
    • Saraya, T.1    Kurai, D.2    Nakagaki, K.3
  • 4
    • 84919498931 scopus 로고    scopus 로고
    • Investigations of Mycoplasma pneumoniae infections in the United States: trends in molecular typing and macrolide resistance from 2006 to 2013
    • 4 Diaz, M.H., Benitez, A.J., Winchell, J.M., Investigations of Mycoplasma pneumoniae infections in the United States: trends in molecular typing and macrolide resistance from 2006 to 2013. J Clin Microbiol 53:1 (2015), 124–130.
    • (2015) J Clin Microbiol , vol.53 , Issue.1 , pp. 124-130
    • Diaz, M.H.1    Benitez, A.J.2    Winchell, J.M.3
  • 5
    • 5644300391 scopus 로고    scopus 로고
    • Mycoplasma pneumoniae and its role as a human pathogen
    • 5 Waites, K.B., Talkington, D.F., Mycoplasma pneumoniae and its role as a human pathogen. Clin Microbiol Rev 17:4 (2004), 697–728.
    • (2004) Clin Microbiol Rev , vol.17 , Issue.4 , pp. 697-728
    • Waites, K.B.1    Talkington, D.F.2
  • 6
    • 59849114319 scopus 로고    scopus 로고
    • New insights into the pathogenesis and detection of Mycoplasma pneumoniae infections
    • 6 Waites, K.B., Balish, M.F., Atkinson, T.P., New insights into the pathogenesis and detection of Mycoplasma pneumoniae infections. Future Microbiol 3:6 (2008), 635–648.
    • (2008) Future Microbiol , vol.3 , Issue.6 , pp. 635-648
    • Waites, K.B.1    Balish, M.F.2    Atkinson, T.P.3
  • 7
    • 25144494029 scopus 로고    scopus 로고
    • A metabolic enzyme as a primary virulence factor of Mycoplasma mycoides subsp. mycoides small colony
    • 7 Pilo, P., Vilei, E.M., Peterhans, E., et al. A metabolic enzyme as a primary virulence factor of Mycoplasma mycoides subsp. mycoides small colony. J Bacteriol 187:19 (2005), 6824–6831.
    • (2005) J Bacteriol , vol.187 , Issue.19 , pp. 6824-6831
    • Pilo, P.1    Vilei, E.M.2    Peterhans, E.3
  • 8
    • 63449129395 scopus 로고    scopus 로고
    • Glycerol metabolism is important for cytotoxicity of Mycoplasma pneumoniae
    • 8 Hames, C., Halbedel, S., Hoppert, M., et al. Glycerol metabolism is important for cytotoxicity of Mycoplasma pneumoniae. J Bacteriol 191:3 (2009), 747–753.
    • (2009) J Bacteriol , vol.191 , Issue.3 , pp. 747-753
    • Hames, C.1    Halbedel, S.2    Hoppert, M.3
  • 9
    • 84939267140 scopus 로고    scopus 로고
    • Structure and proposed mechanism of l-alpha-glycerophosphate oxidase from Mycoplasma pneumoniae
    • 9 Elkhal, C.K., Kean, K.M., Parsonage, D., et al. Structure and proposed mechanism of l-alpha-glycerophosphate oxidase from Mycoplasma pneumoniae. FEBS J 282:16 (2015), 3030–3042.
    • (2015) FEBS J , vol.282 , Issue.16 , pp. 3030-3042
    • Elkhal, C.K.1    Kean, K.M.2    Parsonage, D.3
  • 10
    • 0037335882 scopus 로고    scopus 로고
    • Effects of inhaled fluticasone on bronchial hyperresponsiveness and airway inflammation in Mycoplasma pneumoniae-infected mice
    • 10 Chu, H.W., Campbell, J.A., Harbeck, R.J., et al. Effects of inhaled fluticasone on bronchial hyperresponsiveness and airway inflammation in Mycoplasma pneumoniae-infected mice. Chest, 123(Suppl 3), 2003, 427s.
    • (2003) Chest , vol.123 , pp. 427s
    • Chu, H.W.1    Campbell, J.A.2    Harbeck, R.J.3
  • 11
    • 84920997431 scopus 로고    scopus 로고
    • ADP-ribosylation of NLRP3 by Mycoplasma pneumoniae CARDS toxin regulates inflammasome activity
    • 11 Bose, S., Segovia, J.A., Somarajan, S.R., et al. ADP-ribosylation of NLRP3 by Mycoplasma pneumoniae CARDS toxin regulates inflammasome activity. MBio, 5(6), 2014.
    • (2014) MBio , vol.5 , Issue.6
    • Bose, S.1    Segovia, J.A.2    Somarajan, S.R.3
  • 12
    • 33646271152 scopus 로고    scopus 로고
    • ADP-ribosylating and vacuolating cytotoxin of Mycoplasma pneumoniae represents unique virulence determinant among bacterial pathogens
    • 12 Kannan, T.R., Baseman, J.B., ADP-ribosylating and vacuolating cytotoxin of Mycoplasma pneumoniae represents unique virulence determinant among bacterial pathogens. Proc Natl Acad Sci U S A 103:17 (2006), 6724–6729.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.17 , pp. 6724-6729
    • Kannan, T.R.1    Baseman, J.B.2
  • 13
    • 84908263133 scopus 로고    scopus 로고
    • Annexin A2 mediates Mycoplasma pneumoniae community-acquired respiratory distress syndrome toxin binding to eukaryotic cells
    • 13 Somarajan, S.R., Al-Asadi, F., Ramasamy, K., et al. Annexin A2 mediates Mycoplasma pneumoniae community-acquired respiratory distress syndrome toxin binding to eukaryotic cells. MBio, 5(4), 2014.
    • (2014) MBio , vol.5 , Issue.4
    • Somarajan, S.R.1    Al-Asadi, F.2    Ramasamy, K.3
  • 14
    • 84928252347 scopus 로고    scopus 로고
    • Structure of CARDS toxin, a unique ADP-ribosylating and vacuolating cytotoxin from Mycoplasma pneumoniae
    • 14 Becker, A., Kannan, T.R., Taylor, A.B., et al. Structure of CARDS toxin, a unique ADP-ribosylating and vacuolating cytotoxin from Mycoplasma pneumoniae. Proc Natl Acad Sci U S A 112:16 (2015), 5165–5170.
    • (2015) Proc Natl Acad Sci U S A , vol.112 , Issue.16 , pp. 5165-5170
    • Becker, A.1    Kannan, T.R.2    Taylor, A.B.3
  • 15
    • 84863118263 scopus 로고    scopus 로고
    • Interferon-gamma stimulates p11-dependent surface expression of annexin A2 in lung epithelial cells to enhance phagocytosis
    • 15 Fang, Y.T., Lin, C.F., Wang, C.Y., et al. Interferon-gamma stimulates p11-dependent surface expression of annexin A2 in lung epithelial cells to enhance phagocytosis. J Cell Physiol 227:6 (2012), 2775–2787.
    • (2012) J Cell Physiol , vol.227 , Issue.6 , pp. 2775-2787
    • Fang, Y.T.1    Lin, C.F.2    Wang, C.Y.3
  • 16
    • 34447108077 scopus 로고    scopus 로고
    • Triacylated lipoproteins derived from Mycoplasma pneumoniae activate nuclear factor-kappaB through toll-like receptors 1 and 2
    • 16 Shimizu, T., Kida, Y., Kuwano, K., Triacylated lipoproteins derived from Mycoplasma pneumoniae activate nuclear factor-kappaB through toll-like receptors 1 and 2. Immunology 121:4 (2007), 473–483.
    • (2007) Immunology , vol.121 , Issue.4 , pp. 473-483
    • Shimizu, T.1    Kida, Y.2    Kuwano, K.3
  • 17
    • 84880316344 scopus 로고    scopus 로고
    • Modulation of IL-8 boosted by Mycoplasma pneumoniae lysate in human airway epithelial cells
    • 17 Lee, K.E., Kim, K.W., Hong, J.Y., et al. Modulation of IL-8 boosted by Mycoplasma pneumoniae lysate in human airway epithelial cells. J Clin Immunol 33:6 (2013), 1117–1125.
    • (2013) J Clin Immunol , vol.33 , Issue.6 , pp. 1117-1125
    • Lee, K.E.1    Kim, K.W.2    Hong, J.Y.3
  • 18
    • 84903177349 scopus 로고    scopus 로고
    • Cytadherence of Mycoplasma pneumoniae induces inflammatory responses through autophagy and toll-like receptor 4
    • 18 Shimizu, T., Kimura, Y., Kida, Y., et al. Cytadherence of Mycoplasma pneumoniae induces inflammatory responses through autophagy and toll-like receptor 4. Infect Immun 82:7 (2014), 3076–3086.
    • (2014) Infect Immun , vol.82 , Issue.7 , pp. 3076-3086
    • Shimizu, T.1    Kimura, Y.2    Kida, Y.3
  • 19
    • 78650801273 scopus 로고    scopus 로고
    • Critical Role of Macrophages and Their Activation via MyD88-NFκB Signaling in Lung Innate Immunity to Mycoplasma pneumoniae
    • 19 Lai, J.F., Zindl, C.L., Duffy, L.B., et al. Critical Role of Macrophages and Their Activation via MyD88-NFκB Signaling in Lung Innate Immunity to Mycoplasma pneumoniae. PLoS One, 5(12), 2010, e14417.
    • (2010) PLoS One , vol.5 , Issue.12 , pp. e14417
    • Lai, J.F.1    Zindl, C.L.2    Duffy, L.B.3
  • 20
    • 84931393744 scopus 로고    scopus 로고
    • Genetic variation in SP-A2 leads to differential binding to Mycoplasma pneumoniae membranes and regulation of host responses
    • 20 Ledford, J.G., Voelker, D.R., Addison, K.J., et al. Genetic variation in SP-A2 leads to differential binding to Mycoplasma pneumoniae membranes and regulation of host responses. J Immunol 194:12 (2015), 6123–6132.
    • (2015) J Immunol , vol.194 , Issue.12 , pp. 6123-6132
    • Ledford, J.G.1    Voelker, D.R.2    Addison, K.J.3
  • 21
    • 31944437499 scopus 로고    scopus 로고
    • Mast cells protect mice from Mycoplasma pneumonia
    • 21 Xu, X., Zhang, D., Lyubynska, N., et al. Mast cells protect mice from Mycoplasma pneumonia. Am J Respir Crit Care Med 173:2 (2006), 219–225.
    • (2006) Am J Respir Crit Care Med , vol.173 , Issue.2 , pp. 219-225
    • Xu, X.1    Zhang, D.2    Lyubynska, N.3
  • 22
    • 84862852927 scopus 로고    scopus 로고
    • Mast cell TNF receptors regulate responses to Mycoplasma pneumoniae in surfactant protein A (SP-A)-/- mice
    • 22 Hsia, B.J., Ledford, J.G., Potts-Kant, E.N., et al. Mast cell TNF receptors regulate responses to Mycoplasma pneumoniae in surfactant protein A (SP-A)-/- mice. J Allergy Clin Immunol 130:1 (2012), 205–214.e202.
    • (2012) J Allergy Clin Immunol , vol.130 , Issue.1 , pp. 205-214.e202
    • Hsia, B.J.1    Ledford, J.G.2    Potts-Kant, E.N.3
  • 23
    • 84861772496 scopus 로고    scopus 로고
    • Mycoplasma pneumoniae CARDS toxin induces pulmonary eosinophilic and lymphocytic inflammation
    • 23 Medina, J.L., Coalson, J.J., Brooks, E.G., et al. Mycoplasma pneumoniae CARDS toxin induces pulmonary eosinophilic and lymphocytic inflammation. Am J Respir Cell Mol Biol 46:6 (2012), 815–822.
    • (2012) Am J Respir Cell Mol Biol , vol.46 , Issue.6 , pp. 815-822
    • Medina, J.L.1    Coalson, J.J.2    Brooks, E.G.3
  • 24
    • 84904814170 scopus 로고    scopus 로고
    • Mycoplasma pneumoniae CARDS toxin exacerbates ovalbumin-induced asthma-like inflammation in BALB/c mice
    • 24 Medina, J.L., Coalson, J.J., Brooks, E.G., et al. Mycoplasma pneumoniae CARDS toxin exacerbates ovalbumin-induced asthma-like inflammation in BALB/c mice. PLoS One, 9(7), 2014, e102613.
    • (2014) PLoS One , vol.9 , Issue.7 , pp. e102613
    • Medina, J.L.1    Coalson, J.J.2    Brooks, E.G.3
  • 25
    • 0037369834 scopus 로고    scopus 로고
    • Effects of respiratory Mycoplasma pneumoniae infection on allergen-induced bronchial hyperresponsiveness and lung inflammation in mice
    • 25 Chu, H.W., Honour, J.M., Rawlinson, C.A., et al. Effects of respiratory Mycoplasma pneumoniae infection on allergen-induced bronchial hyperresponsiveness and lung inflammation in mice. Infect Immun 71:3 (2003), 1520–1526.
    • (2003) Infect Immun , vol.71 , Issue.3 , pp. 1520-1526
    • Chu, H.W.1    Honour, J.M.2    Rawlinson, C.A.3
  • 26
    • 0035037089 scopus 로고    scopus 로고
    • Airway inflammation and bronchial hyperresponsiveness after Mycoplasma pneumoniae infection in a murine model
    • 26 Martin, R.J., Chu, H.W., Honour, J.M., et al. Airway inflammation and bronchial hyperresponsiveness after Mycoplasma pneumoniae infection in a murine model. Am J Respir Cell Mol Biol 24:5 (2001), 577–582.
    • (2001) Am J Respir Cell Mol Biol , vol.24 , Issue.5 , pp. 577-582
    • Martin, R.J.1    Chu, H.W.2    Honour, J.M.3
  • 27
    • 84908265637 scopus 로고    scopus 로고
    • Effects of Mycoplasma pneumoniae infection on airway neurokinin-1 receptor expression in BALB/c mice
    • 27 Zhang, H., Wei, B., Shang, Y.X., et al. Effects of Mycoplasma pneumoniae infection on airway neurokinin-1 receptor expression in BALB/c mice. Genet Mol Res 13:4 (2014), 8320–8328.
    • (2014) Genet Mol Res , vol.13 , Issue.4 , pp. 8320-8328
    • Zhang, H.1    Wei, B.2    Shang, Y.X.3
  • 28
    • 84911373369 scopus 로고    scopus 로고
    • Mycoplasma pneumoniae modulates STAT3-STAT6/EGFR-FOXA2 signaling to induce overexpression of airway mucins
    • 28 Hao, Y., Kuang, Z., Jing, J., et al. Mycoplasma pneumoniae modulates STAT3-STAT6/EGFR-FOXA2 signaling to induce overexpression of airway mucins. Infect Immun 82:12 (2014), 5246–5255.
    • (2014) Infect Immun , vol.82 , Issue.12 , pp. 5246-5255
    • Hao, Y.1    Kuang, Z.2    Jing, J.3
  • 29
    • 84874530717 scopus 로고    scopus 로고
    • A novel function of MUC18: amplification of lung inflammation during bacterial infection
    • 29 Wu, Q., Case, S.R., Minor, M.N., et al. A novel function of MUC18: amplification of lung inflammation during bacterial infection. Am J Pathol 182:3 (2013), 819–827.
    • (2013) Am J Pathol , vol.182 , Issue.3 , pp. 819-827
    • Wu, Q.1    Case, S.R.2    Minor, M.N.3
  • 30
    • 20844462091 scopus 로고    scopus 로고
    • Mycoplasma pneumoniae infection increases airway collagen deposition in a murine model of allergic airway inflammation
    • 30 Chu, H.W., Rino, J.G., Wexler, R.B., et al. Mycoplasma pneumoniae infection increases airway collagen deposition in a murine model of allergic airway inflammation. Am J Physiol Lung Cell Mol Physiol 289:1 (2005), L125–L133.
    • (2005) Am J Physiol Lung Cell Mol Physiol , vol.289 , Issue.1 , pp. L125-L133
    • Chu, H.W.1    Rino, J.G.2    Wexler, R.B.3
  • 31
    • 0035286568 scopus 로고    scopus 로고
    • Levels of interleukin-2, interferon-gamma, and interleukin-4 in bronchoalveolar lavage fluid from patients with Mycoplasma pneumonia: implication of tendency toward increased immunoglobulin E production
    • 31 Koh, Y.Y., Park, Y., Lee, H.J., et al. Levels of interleukin-2, interferon-gamma, and interleukin-4 in bronchoalveolar lavage fluid from patients with Mycoplasma pneumonia: implication of tendency toward increased immunoglobulin E production. Pediatrics, 107(3), 2001, E39.
    • (2001) Pediatrics , vol.107 , Issue.3 , pp. E39
    • Koh, Y.Y.1    Park, Y.2    Lee, H.J.3
  • 32
    • 84955179145 scopus 로고    scopus 로고
    • Characteristics of respiratory syncytial virus-induced bronchiolitis co-infection with Mycoplasma pneumoniae and add-on therapy with montelukast
    • 32 Wu, S.H., Chen, X.Q., Kong, X., et al. Characteristics of respiratory syncytial virus-induced bronchiolitis co-infection with Mycoplasma pneumoniae and add-on therapy with montelukast. World J Pediatr 12:1 (2016), 88–95.
    • (2016) World J Pediatr , vol.12 , Issue.1 , pp. 88-95
    • Wu, S.H.1    Chen, X.Q.2    Kong, X.3
  • 33
    • 84936990329 scopus 로고    scopus 로고
    • Increased T cell activation in BALF from children with Mycoplasma pneumoniae pneumonia
    • 33 Guo, L., Liu, F., Lu, M.P., et al. Increased T cell activation in BALF from children with Mycoplasma pneumoniae pneumonia. Pediatr Pulmonol 50:8 (2015), 814–819.
    • (2015) Pediatr Pulmonol , vol.50 , Issue.8 , pp. 814-819
    • Guo, L.1    Liu, F.2    Lu, M.P.3
  • 34
    • 84906953946 scopus 로고    scopus 로고
    • Serial Changes in Serum Eosinophil-associated Mediators between Atopic and Non-atopic Children after Mycoplasma pneumoniae pneumonia
    • 34 Kim, J.H., Cho, T.S., Moon, J.H., et al. Serial Changes in Serum Eosinophil-associated Mediators between Atopic and Non-atopic Children after Mycoplasma pneumoniae pneumonia. Allergy Asthma Immunol Res 6:5 (2014), 428–433.
    • (2014) Allergy Asthma Immunol Res , vol.6 , Issue.5 , pp. 428-433
    • Kim, J.H.1    Cho, T.S.2    Moon, J.H.3
  • 35
    • 84900033466 scopus 로고    scopus 로고
    • Mycoplasma pneumoniae infection in children is a risk factor for developing allergic diseases
    • 35 Ye, Q., Xu, X.J., Shao, W.X., et al. Mycoplasma pneumoniae infection in children is a risk factor for developing allergic diseases. ScientificWorldJournal, 2014, 2014, 986527.
    • (2014) ScientificWorldJournal , vol.2014 , pp. 986527
    • Ye, Q.1    Xu, X.J.2    Shao, W.X.3
  • 36
    • 84929378043 scopus 로고    scopus 로고
    • Changes of serum TNF-alpha, IL-5 and IgE levels in the patients of mycoplasma pneumonia infection with or without bronchial asthma
    • 36 Wang, L., Chen, Q., Shi, C., et al. Changes of serum TNF-alpha, IL-5 and IgE levels in the patients of mycoplasma pneumonia infection with or without bronchial asthma. Int J Clin Exp Med 8:3 (2015), 3901–3906.
    • (2015) Int J Clin Exp Med , vol.8 , Issue.3 , pp. 3901-3906
    • Wang, L.1    Chen, Q.2    Shi, C.3
  • 37
    • 84861881787 scopus 로고    scopus 로고
    • Mycoplasma pneumoniae infection affects the serum levels of vascular endothelial growth factor and interleukin-5 in atopic children
    • 37 Jeong, Y.C., Yeo, M.S., Kim, J.H., et al. Mycoplasma pneumoniae infection affects the serum levels of vascular endothelial growth factor and interleukin-5 in atopic children. Allergy Asthma Immunol Res 4:2 (2012), 92–97.
    • (2012) Allergy Asthma Immunol Res , vol.4 , Issue.2 , pp. 92-97
    • Jeong, Y.C.1    Yeo, M.S.2    Kim, J.H.3
  • 38
    • 84902493813 scopus 로고    scopus 로고
    • Increased risk of refractory Mycoplasma pneumoniae pneumonia in children with atopic sensitization and asthma
    • 38 Shin, J.E., Cheon, B.R., Shim, J.W., et al. Increased risk of refractory Mycoplasma pneumoniae pneumonia in children with atopic sensitization and asthma. Korean J Pediatr 57:6 (2014), 271–277.
    • (2014) Korean J Pediatr , vol.57 , Issue.6 , pp. 271-277
    • Shin, J.E.1    Cheon, B.R.2    Shim, J.W.3
  • 39
    • 84859398835 scopus 로고    scopus 로고
    • SHP-1 as a critical regulator of Mycoplasma pneumoniae-induced inflammation in human asthmatic airway epithelial cells
    • 39 Wang, Y., Zhu, Z., Church, T.D., et al. SHP-1 as a critical regulator of Mycoplasma pneumoniae-induced inflammation in human asthmatic airway epithelial cells. J Immunol 188:7 (2012), 3371–3381.
    • (2012) J Immunol , vol.188 , Issue.7 , pp. 3371-3381
    • Wang, Y.1    Zhu, Z.2    Church, T.D.3
  • 40
    • 84937953575 scopus 로고    scopus 로고
    • Changes in levels of IL-9, IL-17, IFN-gamma, dendritic cell numbers and TLR expression in peripheral blood in asthmatic children with Mycoplasma pneumoniae infection
    • 40 Shao, L., Cong, Z., Li, X., et al. Changes in levels of IL-9, IL-17, IFN-gamma, dendritic cell numbers and TLR expression in peripheral blood in asthmatic children with Mycoplasma pneumoniae infection. Int J Clin Exp Pathol 8:5 (2015), 5263–5272.
    • (2015) Int J Clin Exp Pathol , vol.8 , Issue.5 , pp. 5263-5272
    • Shao, L.1    Cong, Z.2    Li, X.3
  • 41
    • 84866605369 scopus 로고    scopus 로고
    • Toll-like receptors 2, 3 and 4 and thymic stromal lymphopoietin expression in fatal asthma
    • 41 Ferreira, D.S., Annoni, R., Silva, L.F., et al. Toll-like receptors 2, 3 and 4 and thymic stromal lymphopoietin expression in fatal asthma. Clin Exp Allergy 42:10 (2012), 1459–1471.
    • (2012) Clin Exp Allergy , vol.42 , Issue.10 , pp. 1459-1471
    • Ferreira, D.S.1    Annoni, R.2    Silva, L.F.3
  • 42
    • 37549062624 scopus 로고    scopus 로고
    • Asthma and atypical bacterial infection
    • 42 Sutherland, E.R., Martin, R.J., Asthma and atypical bacterial infection. Chest 132:6 (2007), 1962–1966.
    • (2007) Chest , vol.132 , Issue.6 , pp. 1962-1966
    • Sutherland, E.R.1    Martin, R.J.2
  • 43
    • 84861865555 scopus 로고    scopus 로고
    • The role of Mycoplasma pneumoniae infection in asthma
    • 43 Hong, S.J., The role of Mycoplasma pneumoniae infection in asthma. Allergy Asthma Immunol Res 4:2 (2012), 59–61.
    • (2012) Allergy Asthma Immunol Res , vol.4 , Issue.2 , pp. 59-61
    • Hong, S.J.1
  • 45
    • 78349262737 scopus 로고    scopus 로고
    • Chronic macrolide therapy in inflammatory airways diseases
    • 45 Friedlander, A.L., Albert, R.K., Chronic macrolide therapy in inflammatory airways diseases. Chest 138:5 (2010), 1202–1212.
    • (2010) Chest , vol.138 , Issue.5 , pp. 1202-1212
    • Friedlander, A.L.1    Albert, R.K.2
  • 46
    • 0028215761 scopus 로고
    • Association of Mycoplasma pneumoniae antigen with initial onset of bronchial asthma
    • 46 Yano, T., Ichikawa, Y., Komatu, S., et al. Association of Mycoplasma pneumoniae antigen with initial onset of bronchial asthma. Am J Respir Crit Care Med 149:5 (1994), 1348–1353.
    • (1994) Am J Respir Crit Care Med , vol.149 , Issue.5 , pp. 1348-1353
    • Yano, T.1    Ichikawa, Y.2    Komatu, S.3
  • 47
    • 0034477391 scopus 로고    scopus 로고
    • Importance of acute Mycoplasma pneumoniae and Chlamydia pneumoniae infections in children with wheezing
    • 47 Esposito, S., Blasi, F., Arosio, C., et al. Importance of acute Mycoplasma pneumoniae and Chlamydia pneumoniae infections in children with wheezing. Eur Respir J 16:6 (2000), 1142–1146.
    • (2000) Eur Respir J , vol.16 , Issue.6 , pp. 1142-1146
    • Esposito, S.1    Blasi, F.2    Arosio, C.3
  • 48
    • 0343340033 scopus 로고    scopus 로고
    • Late abnormal findings on high-resolution computed tomography after Mycoplasma pneumonia
    • 48 Kim, C.K., Chung, C.Y., Kim, J.S., et al. Late abnormal findings on high-resolution computed tomography after Mycoplasma pneumonia. Pediatrics 105:2 (2000), 372–378.
    • (2000) Pediatrics , vol.105 , Issue.2 , pp. 372-378
    • Kim, C.K.1    Chung, C.Y.2    Kim, J.S.3
  • 49
    • 60049089381 scopus 로고    scopus 로고
    • Innate immunity and vaccines in chlamydial infection with special emphasis on Chlamydia pneumoniae
    • 49 Puolakkainen, M., Innate immunity and vaccines in chlamydial infection with special emphasis on Chlamydia pneumoniae. FEMS Immunol Med Microbiol 55:2 (2009), 167–177.
    • (2009) FEMS Immunol Med Microbiol , vol.55 , Issue.2 , pp. 167-177
    • Puolakkainen, M.1
  • 50
    • 0036739189 scopus 로고    scopus 로고
    • Role of chlamydial heat shock protein 60 in the stimulation of innate immune cells by Chlamydia pneumoniae
    • 50 Costa, C.P., Kirschning, C.J., Busch, D., et al. Role of chlamydial heat shock protein 60 in the stimulation of innate immune cells by Chlamydia pneumoniae. Eur J Immunol 32:9 (2002), 2460–2470.
    • (2002) Eur J Immunol , vol.32 , Issue.9 , pp. 2460-2470
    • Costa, C.P.1    Kirschning, C.J.2    Busch, D.3
  • 51
    • 7244251610 scopus 로고    scopus 로고
    • Heat shock protein 60 from Chlamydia pneumoniae elicits an unusual set of inflammatory responses via Toll-like receptor 2 and 4 in vivo
    • 51 Da Costa, C.U., Wantia, N., Kirschning, C.J., et al. Heat shock protein 60 from Chlamydia pneumoniae elicits an unusual set of inflammatory responses via Toll-like receptor 2 and 4 in vivo. Eur J Immunol 34:10 (2004), 2874–2884.
    • (2004) Eur J Immunol , vol.34 , Issue.10 , pp. 2874-2884
    • Da Costa, C.U.1    Wantia, N.2    Kirschning, C.J.3
  • 52
    • 80855148159 scopus 로고    scopus 로고
    • Heat shock protein 10 of Chlamydophila pneumoniae induces proinflammatory cytokines through Toll-like receptor (TLR) 2 and TLR4 in human monocytes THP-1
    • 52 Zhou, Z., Wu, Y., Chen, L., et al. Heat shock protein 10 of Chlamydophila pneumoniae induces proinflammatory cytokines through Toll-like receptor (TLR) 2 and TLR4 in human monocytes THP-1. In Vitro Cell Dev Biol Anim 47:8 (2011), 541–549.
    • (2011) In Vitro Cell Dev Biol Anim , vol.47 , Issue.8 , pp. 541-549
    • Zhou, Z.1    Wu, Y.2    Chen, L.3
  • 53
    • 44649132540 scopus 로고    scopus 로고
    • Host innate immune receptors and beyond: making sense of microbial infections
    • 53 Ishii, K.J., Koyama, S., Nakagawa, A., et al. Host innate immune receptors and beyond: making sense of microbial infections. Cell Host Microbe 3:6 (2008), 352–363.
    • (2008) Cell Host Microbe , vol.3 , Issue.6 , pp. 352-363
    • Ishii, K.J.1    Koyama, S.2    Nakagawa, A.3
  • 54
    • 84879616878 scopus 로고    scopus 로고
    • MAPK kinase 3 potentiates Chlamydia HSP60-induced inflammatory response through distinct activation of NF-kappaB
    • 54 Kang, Y., Wang, F., Lu, Z., et al. MAPK kinase 3 potentiates Chlamydia HSP60-induced inflammatory response through distinct activation of NF-kappaB. J Immunol 191:1 (2013), 386–394.
    • (2013) J Immunol , vol.191 , Issue.1 , pp. 386-394
    • Kang, Y.1    Wang, F.2    Lu, Z.3
  • 55
    • 33744551792 scopus 로고    scopus 로고
    • 60-kDa heat shock protein of Chlamydia pneumoniae is a target of T-cell immune response
    • 55 Ausiello, C.M., Palazzo, R., Spensieri, F., et al. 60-kDa heat shock protein of Chlamydia pneumoniae is a target of T-cell immune response. J Biol Regul Homeost Agents 19:3–4 (2005), 136–140.
    • (2005) J Biol Regul Homeost Agents , vol.19 , Issue.3-4 , pp. 136-140
    • Ausiello, C.M.1    Palazzo, R.2    Spensieri, F.3
  • 56
    • 33646050050 scopus 로고    scopus 로고
    • 60-kDa heat shock protein of Chlamydia pneumoniae promotes a T helper type 1 immune response through IL-12/IL-23 production in monocyte-derived dendritic cells
    • 56 Ausiello, C.M., Fedele, G., Palazzo, R., et al. 60-kDa heat shock protein of Chlamydia pneumoniae promotes a T helper type 1 immune response through IL-12/IL-23 production in monocyte-derived dendritic cells. Microbes Infect 8:3 (2006), 714–720.
    • (2006) Microbes Infect , vol.8 , Issue.3 , pp. 714-720
    • Ausiello, C.M.1    Fedele, G.2    Palazzo, R.3
  • 57
    • 84907482558 scopus 로고    scopus 로고
    • Chlamydia pneumoniae harness host NLRP3 inflammasome-mediated caspase-1 activation for optimal intracellular growth in murine macrophages
    • 57 Itoh, R., Murakami, I., Chou, B., et al. Chlamydia pneumoniae harness host NLRP3 inflammasome-mediated caspase-1 activation for optimal intracellular growth in murine macrophages. Biochem Biophys Res Commun 452:3 (2014), 689–694.
    • (2014) Biochem Biophys Res Commun , vol.452 , Issue.3 , pp. 689-694
    • Itoh, R.1    Murakami, I.2    Chou, B.3
  • 58
    • 84930995025 scopus 로고    scopus 로고
    • Synergistic costimulatory effect of Chlamydia pneumoniae with carbon nanoparticles on NLRP3 inflammasome-mediated interleukin-1beta secretion in macrophages
    • 58 Matsuo, J., Nakamura, S., Takeda, S., et al. Synergistic costimulatory effect of Chlamydia pneumoniae with carbon nanoparticles on NLRP3 inflammasome-mediated interleukin-1beta secretion in macrophages. Infect Immun 83:7 (2015), 2917–2925.
    • (2015) Infect Immun , vol.83 , Issue.7 , pp. 2917-2925
    • Matsuo, J.1    Nakamura, S.2    Takeda, S.3
  • 59
    • 79959567502 scopus 로고    scopus 로고
    • Caspase-1 dependent IL-1beta secretion is critical for host defense in a mouse model of Chlamydia pneumoniae lung infection
    • 59 Shimada, K., Crother, T.R., Karlin, J., et al. Caspase-1 dependent IL-1beta secretion is critical for host defense in a mouse model of Chlamydia pneumoniae lung infection. PLoS One, 6(6), 2011, e21477.
    • (2011) PLoS One , vol.6 , Issue.6 , pp. e21477
    • Shimada, K.1    Crother, T.R.2    Karlin, J.3
  • 60
    • 77954726266 scopus 로고    scopus 로고
    • Inflammation and fibrosis during Chlamydia pneumoniae infection is regulated by IL-1 and the NLRP3/ASC inflammasome
    • 60 He, X., Mekasha, S., Mavrogiorgos, N., et al. Inflammation and fibrosis during Chlamydia pneumoniae infection is regulated by IL-1 and the NLRP3/ASC inflammasome. J Immunol 184:10 (2010), 5743–5754.
    • (2010) J Immunol , vol.184 , Issue.10 , pp. 5743-5754
    • He, X.1    Mekasha, S.2    Mavrogiorgos, N.3
  • 61
    • 79959572202 scopus 로고    scopus 로고
    • Chlamydia pneumoniae inhibits activated human T lymphocyte proliferation by the induction of apoptotic and pyroptotic pathways
    • 61 Olivares-Zavaleta, N., Carmody, A., Messer, R., et al. Chlamydia pneumoniae inhibits activated human T lymphocyte proliferation by the induction of apoptotic and pyroptotic pathways. J Immunol 186:12 (2011), 7120–7126.
    • (2011) J Immunol , vol.186 , Issue.12 , pp. 7120-7126
    • Olivares-Zavaleta, N.1    Carmody, A.2    Messer, R.3
  • 62
    • 84886385568 scopus 로고    scopus 로고
    • Chlamydia pneumoniae infection in mice induces chronic lung inflammation, iBALT formation, and fibrosis
    • 62 Jupelli, M., Shimada, K., Chiba, N., et al. Chlamydia pneumoniae infection in mice induces chronic lung inflammation, iBALT formation, and fibrosis. PLoS One, 8(10), 2013, e77447.
    • (2013) PLoS One , vol.8 , Issue.10 , pp. e77447
    • Jupelli, M.1    Shimada, K.2    Chiba, N.3
  • 63
    • 77649273626 scopus 로고    scopus 로고
    • Early-life chlamydial lung infection enhances allergic airways disease through age-dependent differences in immunopathology
    • 625.e1–6
    • 63 Horvat, J.C., Starkey, M.R., Kim, R.Y., et al. Early-life chlamydial lung infection enhances allergic airways disease through age-dependent differences in immunopathology. J Allergy Clin Immunol 125:3 (2010), 617–625 625.e1–6.
    • (2010) J Allergy Clin Immunol , vol.125 , Issue.3 , pp. 617-625
    • Horvat, J.C.1    Starkey, M.R.2    Kim, R.Y.3
  • 64
    • 79958050343 scopus 로고    scopus 로고
    • Interleukin-13 promotes susceptibility to chlamydial infection of the respiratory and genital tracts
    • 64 Asquith, K.L., Horvat, J.C., Kaiko, G.E., et al. Interleukin-13 promotes susceptibility to chlamydial infection of the respiratory and genital tracts. PLoS Pathog, 7(5), 2011, e1001339.
    • (2011) PLoS Pathog , vol.7 , Issue.5 , pp. e1001339
    • Asquith, K.L.1    Horvat, J.C.2    Kaiko, G.E.3
  • 65
    • 84876372773 scopus 로고    scopus 로고
    • Constitutive production of IL-13 promotes early-life Chlamydia respiratory infection and allergic airway disease
    • 65 Starkey, M.R., Essilfie, A.T., Horvat, J.C., et al. Constitutive production of IL-13 promotes early-life Chlamydia respiratory infection and allergic airway disease. Mucosal Immunol 6:3 (2013), 569–579.
    • (2013) Mucosal Immunol , vol.6 , Issue.3 , pp. 569-579
    • Starkey, M.R.1    Essilfie, A.T.2    Horvat, J.C.3
  • 66
    • 84963779025 scopus 로고    scopus 로고
    • PD-L1 Promotes Early-life Chlamydia Respiratory Infection-induced Severe Allergic Airway Disease
    • 66 Starkey, M.R., Nguyen, D.H., Brown, A.C., et al. PD-L1 Promotes Early-life Chlamydia Respiratory Infection-induced Severe Allergic Airway Disease. Am J Respir Cell Mol Biol 54:4 (2016), 493–503.
    • (2016) Am J Respir Cell Mol Biol , vol.54 , Issue.4 , pp. 493-503
    • Starkey, M.R.1    Nguyen, D.H.2    Brown, A.C.3
  • 67
    • 84888808366 scopus 로고    scopus 로고
    • Doxycycline suppresses Chlamydia pneumoniae-mediated increases in ongoing immunoglobulin E and interleukin-4 responses by peripheral blood mononuclear cells of patients with allergic asthma
    • 67 Dzhindzhikhashvili, M.S., Joks, R., Smith-Norowitz, T., et al. Doxycycline suppresses Chlamydia pneumoniae-mediated increases in ongoing immunoglobulin E and interleukin-4 responses by peripheral blood mononuclear cells of patients with allergic asthma. J Antimicrob Chemother 68:10 (2013), 2363–2368.
    • (2013) J Antimicrob Chemother , vol.68 , Issue.10 , pp. 2363-2368
    • Dzhindzhikhashvili, M.S.1    Joks, R.2    Smith-Norowitz, T.3
  • 68
    • 77952746227 scopus 로고    scopus 로고
    • Chlamydial respiratory infection during allergen sensitization drives neutrophilic allergic airways disease
    • 68 Horvat, J.C., Starkey, M.R., Kim, R.Y., et al. Chlamydial respiratory infection during allergen sensitization drives neutrophilic allergic airways disease. J Immunol 184:8 (2010), 4159–4169.
    • (2010) J Immunol , vol.184 , Issue.8 , pp. 4159-4169
    • Horvat, J.C.1    Starkey, M.R.2    Kim, R.Y.3
  • 69
    • 84929457101 scopus 로고    scopus 로고
    • Macrolide therapy suppresses key features of experimental steroid-sensitive and steroid-insensitive asthma
    • 69 Essilfie, A.T., Horvat, J.C., Kim, R.Y., et al. Macrolide therapy suppresses key features of experimental steroid-sensitive and steroid-insensitive asthma. Thorax 70:5 (2015), 458–467.
    • (2015) Thorax , vol.70 , Issue.5 , pp. 458-467
    • Essilfie, A.T.1    Horvat, J.C.2    Kim, R.Y.3
  • 70
    • 78650325777 scopus 로고    scopus 로고
    • Infectious Chlamydia pneumoniae is associated with elevated interleukin-8 and airway neutrophilia in children with refractory asthma
    • 70 Patel, K.K., Vicencio, A.G., Du, Z., et al. Infectious Chlamydia pneumoniae is associated with elevated interleukin-8 and airway neutrophilia in children with refractory asthma. Pediatr Infect Dis J 29:12 (2010), 1093–1098.
    • (2010) Pediatr Infect Dis J , vol.29 , Issue.12 , pp. 1093-1098
    • Patel, K.K.1    Vicencio, A.G.2    Du, Z.3
  • 71
    • 71249118291 scopus 로고    scopus 로고
    • Azithromycin, clarithromycin and telithromycin inhibit MUC5AC induction by Chlamydophila pneumoniae in airway epithelial cells
    • 71 Morinaga, Y., Yanagihara, K., Miyashita, N., et al. Azithromycin, clarithromycin and telithromycin inhibit MUC5AC induction by Chlamydophila pneumoniae in airway epithelial cells. Pulm Pharmacol Ther 22:6 (2009), 580–586.
    • (2009) Pulm Pharmacol Ther , vol.22 , Issue.6 , pp. 580-586
    • Morinaga, Y.1    Yanagihara, K.2    Miyashita, N.3
  • 72
    • 84859846008 scopus 로고    scopus 로고
    • Chlamydophila pneumoniae inhibits corticosteroid-induced suppression of metalloproteinase-9 and tissue inhibitor metalloproteinase-1 secretion by human peripheral blood mononuclear cells
    • 72 Park, C.S., Lee, Y.S., Kwon, H.S., et al. Chlamydophila pneumoniae inhibits corticosteroid-induced suppression of metalloproteinase-9 and tissue inhibitor metalloproteinase-1 secretion by human peripheral blood mononuclear cells. J Med Microbiol 61:Pt 5 (2012), 705–711.
    • (2012) J Med Microbiol , vol.61 , pp. 705-711
    • Park, C.S.1    Lee, Y.S.2    Kwon, H.S.3
  • 73
    • 77952776081 scopus 로고    scopus 로고
    • Chlamydophila pneumoniae enhances secretion of VEGF, TGF-beta and TIMP-1 from human bronchial epithelial cells under Th2 dominant microenvironment
    • 73 Park, C.S., Kim, T.B., Moon, K.A., et al. Chlamydophila pneumoniae enhances secretion of VEGF, TGF-beta and TIMP-1 from human bronchial epithelial cells under Th2 dominant microenvironment. Allergy Asthma Immunol Res 2:1 (2010), 41–47.
    • (2010) Allergy Asthma Immunol Res , vol.2 , Issue.1 , pp. 41-47
    • Park, C.S.1    Kim, T.B.2    Moon, K.A.3
  • 74
    • 69249212223 scopus 로고    scopus 로고
    • Chlamydophila pneumoniae triggers release of CCL20 and vascular endothelial growth factor from human bronchial epithelial cells through enhanced intracellular oxidative stress and MAPK activation
    • 74 Kim, T.B., Moon, K.A., Lee, K.Y., et al. Chlamydophila pneumoniae triggers release of CCL20 and vascular endothelial growth factor from human bronchial epithelial cells through enhanced intracellular oxidative stress and MAPK activation. J Clin Immunol 29:5 (2009), 629–636.
    • (2009) J Clin Immunol , vol.29 , Issue.5 , pp. 629-636
    • Kim, T.B.1    Moon, K.A.2    Lee, K.Y.3
  • 75
    • 84884216473 scopus 로고    scopus 로고
    • Severity of allergic airway disease due to house dust mite allergen is not increased after clinical recovery of lung infection with Chlamydia pneumoniae in mice
    • 75 Dutow, P., Lingner, S., Laudeley, R., et al. Severity of allergic airway disease due to house dust mite allergen is not increased after clinical recovery of lung infection with Chlamydia pneumoniae in mice. Infect Immun 81:9 (2013), 3366–3374.
    • (2013) Infect Immun , vol.81 , Issue.9 , pp. 3366-3374
    • Dutow, P.1    Lingner, S.2    Laudeley, R.3
  • 76
    • 79958753438 scopus 로고    scopus 로고
    • Chlamydia pneumoniae infection induced allergic airway sensitization is controlled by regulatory T-cells and plasmacytoid dendritic cells
    • 76 Crother, T.R., Schroder, N.W., Karlin, J., et al. Chlamydia pneumoniae infection induced allergic airway sensitization is controlled by regulatory T-cells and plasmacytoid dendritic cells. PLoS One, 6(6), 2011, e20784.
    • (2011) PLoS One , vol.6 , Issue.6 , pp. e20784
    • Crother, T.R.1    Schroder, N.W.2    Karlin, J.3
  • 77
    • 84927643719 scopus 로고    scopus 로고
    • Mast cells play an important role in Chlamydia pneumoniae lung infection by facilitating immune cell recruitment into the airway
    • 77 Chiba, N., Shimada, K., Chen, S., et al. Mast cells play an important role in Chlamydia pneumoniae lung infection by facilitating immune cell recruitment into the airway. J Immunol 194:8 (2015), 3840–3851.
    • (2015) J Immunol , vol.194 , Issue.8 , pp. 3840-3851
    • Chiba, N.1    Shimada, K.2    Chen, S.3
  • 78
    • 34548831998 scopus 로고    scopus 로고
    • The development of asthma in wheezing infants with Chlamydia pneumoniae infection
    • 78 Zaitsu, M., The development of asthma in wheezing infants with Chlamydia pneumoniae infection. J Asthma 44:7 (2007), 565–568.
    • (2007) J Asthma , vol.44 , Issue.7 , pp. 565-568
    • Zaitsu, M.1
  • 79
    • 0025837626 scopus 로고
    • Association of Chlamydia pneumoniae (strain TWAR) infection with wheezing, asthmatic bronchitis, and adult-onset asthma
    • 79 Hahn, D.L., Dodge, R.W., Golubjatnikov, R., Association of Chlamydia pneumoniae (strain TWAR) infection with wheezing, asthmatic bronchitis, and adult-onset asthma. JAMA 266:2 (1991), 225–230.
    • (1991) JAMA , vol.266 , Issue.2 , pp. 225-230
    • Hahn, D.L.1    Dodge, R.W.2    Golubjatnikov, R.3
  • 80
    • 0031933437 scopus 로고    scopus 로고
    • Chronic Chlamydia pneumoniae infection and asthma exacerbations in children
    • 80 Cunningham, A.F., Johnston, S.L., Julious, S.A., et al. Chronic Chlamydia pneumoniae infection and asthma exacerbations in children. Eur Respir J 11:2 (1998), 345–349.
    • (1998) Eur Respir J , vol.11 , Issue.2 , pp. 345-349
    • Cunningham, A.F.1    Johnston, S.L.2    Julious, S.A.3
  • 81
    • 2442696372 scopus 로고    scopus 로고
    • Mycoplasma pneumoniae and asthma in children
    • 81 Biscardi, S., Lorrot, M., Marc, E., et al. Mycoplasma pneumoniae and asthma in children. Clin Infect Dis 38:10 (2004), 1341–1346.
    • (2004) Clin Infect Dis , vol.38 , Issue.10 , pp. 1341-1346
    • Biscardi, S.1    Lorrot, M.2    Marc, E.3
  • 82
    • 0029775277 scopus 로고    scopus 로고
    • Association of Chlamydia pneumoniae IgA antibodies with recently symptomatic asthma
    • 82 Hahn, D.L., Anttila, T., Saikku, P., Association of Chlamydia pneumoniae IgA antibodies with recently symptomatic asthma. Epidemiol Infect 117:3 (1996), 513–517.
    • (1996) Epidemiol Infect , vol.117 , Issue.3 , pp. 513-517
    • Hahn, D.L.1    Anttila, T.2    Saikku, P.3
  • 83
    • 0033836415 scopus 로고    scopus 로고
    • Chlamydia pneumoniae antibodies and adult-onset asthma
    • 83 Hahn, D.L., Chlamydia pneumoniae antibodies and adult-onset asthma. J Allergy Clin Immunol, 106, 2000, 404.
    • (2000) J Allergy Clin Immunol , vol.106 , pp. 404
    • Hahn, D.L.1
  • 84
    • 0025980344 scopus 로고
    • Erythromycin reduces the severity of bronchial hyperresponsiveness in asthma
    • 84 Miyatake, H., Taki, F., Taniguchi, H., et al. Erythromycin reduces the severity of bronchial hyperresponsiveness in asthma. Chest 99:3 (1991), 670–673.
    • (1991) Chest , vol.99 , Issue.3 , pp. 670-673
    • Miyatake, H.1    Taki, F.2    Taniguchi, H.3
  • 85
    • 2442453846 scopus 로고    scopus 로고
    • Clarithromycin reduces the severity of bronchial hyperresponsiveness in patients with asthma
    • 85 Kostadima, E., Tsiodras, S., Alexopoulos, E.I., et al. Clarithromycin reduces the severity of bronchial hyperresponsiveness in patients with asthma. Eur Respir J 23:5 (2004), 714–717.
    • (2004) Eur Respir J , vol.23 , Issue.5 , pp. 714-717
    • Kostadima, E.1    Tsiodras, S.2    Alexopoulos, E.I.3
  • 86
    • 84863670329 scopus 로고    scopus 로고
    • Azithromycin for bronchial asthma in adults: an effectiveness trial
    • 86 Hahn, D.L., Grasmick, M., Hetzel, S., et al. Azithromycin for bronchial asthma in adults: an effectiveness trial. J Am Board Fam Med 25:4 (2012), 442–459.
    • (2012) J Am Board Fam Med , vol.25 , Issue.4 , pp. 442-459
    • Hahn, D.L.1    Grasmick, M.2    Hetzel, S.3
  • 87
    • 34248589602 scopus 로고    scopus 로고
    • Secondary outcomes of a pilot randomized trial of azithromycin treatment for asthma
    • 87 Hahn, D.L., Plane, M.B., Mahdi, O.S., et al. Secondary outcomes of a pilot randomized trial of azithromycin treatment for asthma. PLoS Clin Trials, 1(2), 2006, e11.
    • (2006) PLoS Clin Trials , vol.1 , Issue.2 , pp. e11
    • Hahn, D.L.1    Plane, M.B.2    Mahdi, O.S.3
  • 88
    • 38348998987 scopus 로고    scopus 로고
    • Clarithromycin targets neutrophilic airway inflammation in refractory asthma
    • 88 Simpson, J.L., Powell, H., Boyle, M.J., et al. Clarithromycin targets neutrophilic airway inflammation in refractory asthma. Am J Respir Crit Care Med 177:2 (2008), 148–155.
    • (2008) Am J Respir Crit Care Med , vol.177 , Issue.2 , pp. 148-155
    • Simpson, J.L.1    Powell, H.2    Boyle, M.J.3
  • 89
    • 0032980088 scopus 로고    scopus 로고
    • Anti-inflammatory effect of roxithromycin in patients with aspirin-intolerant asthma
    • 89 Shoji, T., Yoshida, S., Sakamoto, H., et al. Anti-inflammatory effect of roxithromycin in patients with aspirin-intolerant asthma. Clin Exp Allergy 29:7 (1999), 950–956.
    • (1999) Clin Exp Allergy , vol.29 , Issue.7 , pp. 950-956
    • Shoji, T.1    Yoshida, S.2    Sakamoto, H.3
  • 90
    • 84875219719 scopus 로고    scopus 로고
    • Azithromycin for prevention of exacerbations in severe asthma (AZISAST): a multicentre randomised double-blind placebo-controlled trial
    • 90 Brusselle, G.G., Vanderstichele, C., Jordens, P., et al. Azithromycin for prevention of exacerbations in severe asthma (AZISAST): a multicentre randomised double-blind placebo-controlled trial. Thorax 68:4 (2013), 322–329.
    • (2013) Thorax , vol.68 , Issue.4 , pp. 322-329
    • Brusselle, G.G.1    Vanderstichele, C.2    Jordens, P.3
  • 91
    • 0014753013 scopus 로고
    • The use of macrolide antibiotic substances in the treatment of asthma
    • 91 Itkin, I.H., Menzel, M.L., The use of macrolide antibiotic substances in the treatment of asthma. J Allergy 45:3 (1970), 146–162.
    • (1970) J Allergy , vol.45 , Issue.3 , pp. 146-162
    • Itkin, I.H.1    Menzel, M.L.2
  • 92
    • 0019214735 scopus 로고
    • Efficacy of troleandomycin in outpatients with severe, corticosteroid-dependent asthma
    • 92 Zeiger, R.S., Schatz, M., Sperling, W., et al. Efficacy of troleandomycin in outpatients with severe, corticosteroid-dependent asthma. J Allergy Clin Immunol 66:6 (1980), 438–446.
    • (1980) J Allergy Clin Immunol , vol.66 , Issue.6 , pp. 438-446
    • Zeiger, R.S.1    Schatz, M.2    Sperling, W.3
  • 93
    • 0027524477 scopus 로고
    • Troleandomycin in the treatment of difficult asthma
    • 93 Siracusa, A., Brugnami, G., Fiordi, T., et al. Troleandomycin in the treatment of difficult asthma. J Allergy Clin Immunol 92:5 (1993), 677–682.
    • (1993) J Allergy Clin Immunol , vol.92 , Issue.5 , pp. 677-682
    • Siracusa, A.1    Brugnami, G.2    Fiordi, T.3
  • 94
    • 0027417959 scopus 로고
    • Efficacy and safety of low-dose troleandomycin therapy in children with severe, steroid-requiring asthma
    • 94 Kamada, A.K., Hill, M.R., Iklé, D.N., et al. Efficacy and safety of low-dose troleandomycin therapy in children with severe, steroid-requiring asthma. J Allergy Clin Immunol 91:4 (1993), 873–882.
    • (1993) J Allergy Clin Immunol , vol.91 , Issue.4 , pp. 873-882
    • Kamada, A.K.1    Hill, M.R.2    Iklé, D.N.3
  • 95
    • 0027518873 scopus 로고
    • A double-blind study of troleandomycin and methylprednisolone in asthmatic subjects who require daily corticosteroids
    • 95 Nelson, H.S., Hamilos, D.L., Corsello, P.R., et al. A double-blind study of troleandomycin and methylprednisolone in asthmatic subjects who require daily corticosteroids. Am Rev Respir Dis 147:2 (1993), 398–404.
    • (1993) Am Rev Respir Dis , vol.147 , Issue.2 , pp. 398-404
    • Nelson, H.S.1    Hamilos, D.L.2    Corsello, P.R.3
  • 96
    • 0034544739 scopus 로고    scopus 로고
    • Long-term clarithromycin decreases prednisone requirements in elderly patients with prednisone-dependent asthma
    • 96 Garey, K.W., Rubinstein, I., Gotfried, M.H., et al. Long-term clarithromycin decreases prednisone requirements in elderly patients with prednisone-dependent asthma. Chest 118:6 (2000), 1826–1827.
    • (2000) Chest , vol.118 , Issue.6 , pp. 1826-1827
    • Garey, K.W.1    Rubinstein, I.2    Gotfried, M.H.3
  • 97
    • 0019182871 scopus 로고
    • The effect of troleandomycin on methylprednisolone elimination
    • 97 Szefler, S.J., Rose, J.Q., Ellis, E.F., et al. The effect of troleandomycin on methylprednisolone elimination. J Allergy Clin Immunol 66:6 (1980), 447–451.
    • (1980) J Allergy Clin Immunol , vol.66 , Issue.6 , pp. 447-451
    • Szefler, S.J.1    Rose, J.Q.2    Ellis, E.F.3
  • 98
    • 57149124346 scopus 로고    scopus 로고
    • Azithromycin or montelukast as inhaled corticosteroid-sparing agents in moderate-to-severe childhood asthma study
    • 98 Strunk, R.C., Bacharier, L.B., Phillips, B.R., et al. Azithromycin or montelukast as inhaled corticosteroid-sparing agents in moderate-to-severe childhood asthma study. J Allergy Clin Immunol 122:6 (2008), 1138–1144.e4.
    • (2008) J Allergy Clin Immunol , vol.122 , Issue.6 , pp. 1138-1144.e4
    • Strunk, R.C.1    Bacharier, L.B.2    Phillips, B.R.3
  • 100
    • 84874733216 scopus 로고    scopus 로고
    • Microbes and mucosal immune responses in asthma
    • 100 Hansel, T.T., Johnston, S.L., Openshaw, P.J., Microbes and mucosal immune responses in asthma. Lancet 381:9869 (2013), 861–873.
    • (2013) Lancet , vol.381 , Issue.9869 , pp. 861-873
    • Hansel, T.T.1    Johnston, S.L.2    Openshaw, P.J.3
  • 101
    • 84918493756 scopus 로고    scopus 로고
    • The respiratory microbiome and innate immunity in asthma
    • 101 Huang, Y.J., The respiratory microbiome and innate immunity in asthma. Curr Opin Pulm Med 21:1 (2015), 27–32.
    • (2015) Curr Opin Pulm Med , vol.21 , Issue.1 , pp. 27-32
    • Huang, Y.J.1
  • 102
    • 84902201196 scopus 로고    scopus 로고
    • Lung microbiota promotes tolerance to allergens in neonates via PD-L1
    • 102 Gollwitzer, E.S., Saglani, S., Trompette, A., et al. Lung microbiota promotes tolerance to allergens in neonates via PD-L1. Nat Med 20:6 (2014), 642–647.
    • (2014) Nat Med , vol.20 , Issue.6 , pp. 642-647
    • Gollwitzer, E.S.1    Saglani, S.2    Trompette, A.3
  • 103
    • 84922479758 scopus 로고    scopus 로고
    • Host-microorganism interactions in lung diseases
    • 103 Marsland, B.J., Gollwitzer, E.S., Host-microorganism interactions in lung diseases. Nat Rev Immunol 14:12 (2014), 827–835.
    • (2014) Nat Rev Immunol , vol.14 , Issue.12 , pp. 827-835
    • Marsland, B.J.1    Gollwitzer, E.S.2
  • 104
  • 105
    • 84871995420 scopus 로고    scopus 로고
    • The hygiene hypothesis in allergy and asthma: an update
    • 105 Brooks, C., Pearce, N., Douwes, J., The hygiene hypothesis in allergy and asthma: an update. Curr Opin Allergy Clin Immunol 13:1 (2013), 70–77.
    • (2013) Curr Opin Allergy Clin Immunol , vol.13 , Issue.1 , pp. 70-77
    • Brooks, C.1    Pearce, N.2    Douwes, J.3
  • 106
    • 84906944544 scopus 로고    scopus 로고
    • Effects of early-life exposure to allergens and bacteria on recurrent wheeze and atopy in urban children
    • 106 Lynch, S.V., Wood, R.A., Boushey, H., et al. Effects of early-life exposure to allergens and bacteria on recurrent wheeze and atopy in urban children. J Allergy Clin Immunol 134:3 (2014), 593–601.e12.
    • (2014) J Allergy Clin Immunol , vol.134 , Issue.3 , pp. 593-601.e12
    • Lynch, S.V.1    Wood, R.A.2    Boushey, H.3
  • 107
    • 84947420101 scopus 로고    scopus 로고
    • New developments providing mechanistic insight into the impact of the microbiota on allergic disease
    • 107 McCoy, K.D., Koller, Y., New developments providing mechanistic insight into the impact of the microbiota on allergic disease. Clin Immunol 159:2 (2015), 170–176.
    • (2015) Clin Immunol , vol.159 , Issue.2 , pp. 170-176
    • McCoy, K.D.1    Koller, Y.2
  • 108
    • 80052272960 scopus 로고    scopus 로고
    • Reduced diversity of the intestinal microbiota during infancy is associated with increased risk of allergic disease at school age
    • 108 Bisgaard, H., Li, N., Bonnelykke, K., et al. Reduced diversity of the intestinal microbiota during infancy is associated with increased risk of allergic disease at school age. J Allergy Clin Immunol 128:3 (2011), 646–652.e1-5.
    • (2011) J Allergy Clin Immunol , vol.128 , Issue.3 , pp. 646-652.e1-5
    • Bisgaard, H.1    Li, N.2    Bonnelykke, K.3
  • 109
    • 84929308764 scopus 로고    scopus 로고
    • Microbiota in allergy and asthma and the emerging relationship with the gut microbiome
    • 109 Fujimura, K.E., Lynch, S.V., Microbiota in allergy and asthma and the emerging relationship with the gut microbiome. Cell Host Microbe 17:5 (2015), 592–602.
    • (2015) Cell Host Microbe , vol.17 , Issue.5 , pp. 592-602
    • Fujimura, K.E.1    Lynch, S.V.2
  • 110
    • 84893704050 scopus 로고    scopus 로고
    • Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis
    • 110 Trompette, A., Gollwitzer, E.S., Yadava, K., et al. Gut microbiota metabolism of dietary fiber influences allergic airway disease and hematopoiesis. Nat Med 20:2 (2014), 159–166.
    • (2014) Nat Med , vol.20 , Issue.2 , pp. 159-166
    • Trompette, A.1    Gollwitzer, E.S.2    Yadava, K.3
  • 111
    • 84908045907 scopus 로고    scopus 로고
    • Microbial communities in the upper respiratory tract of patients with asthma and chronic obstructive pulmonary disease
    • 111 Park, H., Shin, J.W., Park, S.G., et al. Microbial communities in the upper respiratory tract of patients with asthma and chronic obstructive pulmonary disease. PLoS One, 9(10), 2014, e109710.
    • (2014) PLoS One , vol.9 , Issue.10 , pp. e109710
    • Park, H.1    Shin, J.W.2    Park, S.G.3
  • 112
    • 84873405282 scopus 로고    scopus 로고
    • Asthma-associated differences in microbial composition of induced sputum
    • 112 Marri, P.R., Stern, D.A., Wright, A.L., et al. Asthma-associated differences in microbial composition of induced sputum. J Allergy Clin Immunol 131:2 (2013), 346–352.e1-3.
    • (2013) J Allergy Clin Immunol , vol.131 , Issue.2 , pp. 346-352.e1-3
    • Marri, P.R.1    Stern, D.A.2    Wright, A.L.3
  • 113
    • 79551495183 scopus 로고    scopus 로고
    • Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma
    • 113 Huang, Y.J., Nelson, C.E., Brodie, E.L., et al. Airway microbiota and bronchial hyperresponsiveness in patients with suboptimally controlled asthma. J Allergy Clin Immunol 127:2 (2011), 372–381.e1-3.
    • (2011) J Allergy Clin Immunol , vol.127 , Issue.2 , pp. 372-381.e1-3
    • Huang, Y.J.1    Nelson, C.E.2    Brodie, E.L.3
  • 114
    • 84943456033 scopus 로고    scopus 로고
    • The airway microbiome in patients with severe asthma: associations with disease features and severity
    • 114 Huang, Y.J., Nariya, S., Harris, J.M., et al. The airway microbiome in patients with severe asthma: associations with disease features and severity. J Allergy Clin Immunol 136:4 (2015), 874–884.
    • (2015) J Allergy Clin Immunol , vol.136 , Issue.4 , pp. 874-884
    • Huang, Y.J.1    Nariya, S.2    Harris, J.M.3
  • 115
    • 84903553827 scopus 로고    scopus 로고
    • Potentially pathogenic airway bacteria and neutrophilic inflammation in treatment resistant severe asthma
    • 115 Green, B.J., Wiriyachaiporn, S., Grainge, C., et al. Potentially pathogenic airway bacteria and neutrophilic inflammation in treatment resistant severe asthma. PLoS One, 9(6), 2014, e100645.
    • (2014) PLoS One , vol.9 , Issue.6 , pp. e100645
    • Green, B.J.1    Wiriyachaiporn, S.2    Grainge, C.3
  • 116
    • 84887923275 scopus 로고    scopus 로고
    • The effects of airway microbiome on corticosteroid responsiveness in asthma
    • 116 Goleva, E., Jackson, L.P., Harris, J.K., et al. The effects of airway microbiome on corticosteroid responsiveness in asthma. Am J Respir Crit Care Med 188:10 (2013), 1193–1201.
    • (2013) Am J Respir Crit Care Med , vol.188 , Issue.10 , pp. 1193-1201
    • Goleva, E.1    Jackson, L.P.2    Harris, J.K.3
  • 117
    • 84902147234 scopus 로고    scopus 로고
    • The impact of azithromycin therapy on the airway microbiota in asthma
    • 117 Slater, M., Rivett, D.W., Williams, L., et al. The impact of azithromycin therapy on the airway microbiota in asthma. Thorax 69 (2014), 673–674.
    • (2014) Thorax , vol.69 , pp. 673-674
    • Slater, M.1    Rivett, D.W.2    Williams, L.3
  • 118
    • 81255157031 scopus 로고    scopus 로고
    • The emerging relationship between the airway microbiota and chronic respiratory disease: clinical implications
    • 118 Huang, Y.J., Lynch, S.V., The emerging relationship between the airway microbiota and chronic respiratory disease: clinical implications. Expert Rev Respir Med 5:6 (2011), 809–821.
    • (2011) Expert Rev Respir Med , vol.5 , Issue.6 , pp. 809-821
    • Huang, Y.J.1    Lynch, S.V.2
  • 119
    • 84893910857 scopus 로고    scopus 로고
    • The microbiome and asthma
    • 119 Huang, Y.J., Boushey, H.A., The microbiome and asthma. Ann Am Thorac Soc 11:Suppl 1 (2014), S48–S51.
    • (2014) Ann Am Thorac Soc , vol.11 , pp. S48-S51
    • Huang, Y.J.1    Boushey, H.A.2
  • 120
    • 84885191350 scopus 로고    scopus 로고
    • Asthma microbiome studies and the potential for new therapeutic strategies
    • 120 Huang, Y.J., Asthma microbiome studies and the potential for new therapeutic strategies. Curr Allergy Asthma Rep 13:5 (2013), 453–461.
    • (2013) Curr Allergy Asthma Rep , vol.13 , Issue.5 , pp. 453-461
    • Huang, Y.J.1
  • 121
    • 84879234270 scopus 로고    scopus 로고
    • Asthmatic children have increased specific anti-Mycoplasma pneumoniae IgM but not IgG or IgE-values independent of history of respiratory tract infection
    • 121 Smith-Norowitz, T.A., Silverberg, J.I., Kusonruksa, M., et al. Asthmatic children have increased specific anti-Mycoplasma pneumoniae IgM but not IgG or IgE-values independent of history of respiratory tract infection. Pediatr Infect Dis J 32:6 (2013), 599–603.
    • (2013) Pediatr Infect Dis J , vol.32 , Issue.6 , pp. 599-603
    • Smith-Norowitz, T.A.1    Silverberg, J.I.2    Kusonruksa, M.3
  • 122
    • 85028142668 scopus 로고    scopus 로고
    • Comparison of Mycoplasma pneumoniae Infections in asthmatic children versus asthmatic adults
    • 122 Bebear, C., Raherison, C., Nacka, F., et al. Comparison of Mycoplasma pneumoniae Infections in asthmatic children versus asthmatic adults. Pediatr Infect Dis J 33:3 (2014), e71–e75.
    • (2014) Pediatr Infect Dis J , vol.33 , Issue.3 , pp. e71-e75
    • Bebear, C.1    Raherison, C.2    Nacka, F.3
  • 123
    • 33750143784 scopus 로고    scopus 로고
    • Effect of clarithromycin on cytokines and chemokines in children with an acute exacerbation of recurrent wheezing: a double-blind, randomized, placebo-controlled trial
    • 123 Fonseca-Aten, M., Okada, P.J., Bowlware, K.L., et al. Effect of clarithromycin on cytokines and chemokines in children with an acute exacerbation of recurrent wheezing: a double-blind, randomized, placebo-controlled trial. Ann Allergy Asthma Immunol 97:4 (2006), 457–463.
    • (2006) Ann Allergy Asthma Immunol , vol.97 , Issue.4 , pp. 457-463
    • Fonseca-Aten, M.1    Okada, P.J.2    Bowlware, K.L.3
  • 124
    • 84876664608 scopus 로고    scopus 로고
    • Mycoplasma pneumoniae in children with acute and refractory asthma
    • 124 Wood, P.R., Hill, V.L., Burks, M.L., et al. Mycoplasma pneumoniae in children with acute and refractory asthma. Ann Allergy Asthma Immunol 110:5 (2013), 328–334.e1.
    • (2013) Ann Allergy Asthma Immunol , vol.110 , Issue.5 , pp. 328-334.e1
    • Wood, P.R.1    Hill, V.L.2    Burks, M.L.3
  • 125
    • 0031781980 scopus 로고    scopus 로고
    • Detection of Mycoplasma pneumoniae in the airways of adults with chronic asthma
    • 125 Kraft, M., Cassell, G.H., Henson, J.E., et al. Detection of Mycoplasma pneumoniae in the airways of adults with chronic asthma. Am J Respir Crit Care Med 158:3 (1998), 998–1001.
    • (1998) Am J Respir Crit Care Med , vol.158 , Issue.3 , pp. 998-1001
    • Kraft, M.1    Cassell, G.H.2    Henson, J.E.3
  • 126
    • 0035034606 scopus 로고    scopus 로고
    • A link between chronic asthma and chronic infection
    • 126 Martin, R.J., Kraft, M., Chu, H.W., et al. A link between chronic asthma and chronic infection. J Allergy Clin Immunol 107:4 (2001), 595–601.
    • (2001) J Allergy Clin Immunol , vol.107 , Issue.4 , pp. 595-601
    • Martin, R.J.1    Kraft, M.2    Chu, H.W.3
  • 127
    • 0037323122 scopus 로고    scopus 로고
    • Atypical Pathogen Infection in Adults with Acute Exacerbation of Bronchial Asthma
    • 127 Lieberman, D., Lieberman, D., Printz, S., et al. Atypical Pathogen Infection in Adults with Acute Exacerbation of Bronchial Asthma. Am J Respir Crit Care Med 167:3 (2003), 406–410.
    • (2003) Am J Respir Crit Care Med , vol.167 , Issue.3 , pp. 406-410
    • Lieberman, D.1    Lieberman, D.2    Printz, S.3
  • 128
    • 80051486855 scopus 로고    scopus 로고
    • Persistence of community-acquired respiratory distress syndrome toxin-producing Mycoplasma pneumoniae in refractory asthma
    • 128 Peters, J., Singh, H., Brooks, E.G., et al. Persistence of community-acquired respiratory distress syndrome toxin-producing Mycoplasma pneumoniae in refractory asthma. Chest 140:2 (2011), 401–407.
    • (2011) Chest , vol.140 , Issue.2 , pp. 401-407
    • Peters, J.1    Singh, H.2    Brooks, E.G.3
  • 129
    • 84867582390 scopus 로고    scopus 로고
    • Chlamydia pneumoniae infection associated with uncontrolled asthma: a hospital based cross sectional study
    • 129 Awasthi, S., Yadav, K.K., Agarwal, J., Chlamydia pneumoniae infection associated with uncontrolled asthma: a hospital based cross sectional study. Indian J Pediatr 79:10 (2012), 1318–1322.
    • (2012) Indian J Pediatr , vol.79 , Issue.10 , pp. 1318-1322
    • Awasthi, S.1    Yadav, K.K.2    Agarwal, J.3
  • 130
    • 8644237367 scopus 로고    scopus 로고
    • Increased frequency of detection of Chlamydophila pneumoniae in asthma
    • 130 Biscione, G.L., Corne, J., Chauhan, A.J., et al. Increased frequency of detection of Chlamydophila pneumoniae in asthma. Eur Respir J 24:5 (2004), 745–749.
    • (2004) Eur Respir J , vol.24 , Issue.5 , pp. 745-749
    • Biscione, G.L.1    Corne, J.2    Chauhan, A.J.3
  • 131
    • 0031805459 scopus 로고    scopus 로고
    • Chlamydia pneumoniae and exacerbations of asthma in adults
    • 131 Miyashita, N., Kubota, Y., Nakajima, M., et al. Chlamydia pneumoniae and exacerbations of asthma in adults. Ann Allergy Asthma Immunol 80:5 (1998), 405–409.
    • (1998) Ann Allergy Asthma Immunol , vol.80 , Issue.5 , pp. 405-409
    • Miyashita, N.1    Kubota, Y.2    Nakajima, M.3
  • 132
    • 0028595582 scopus 로고
    • Acute exacerbations of asthma in adults: role of Chlamydia pneumoniae infection
    • 132 Allegra, L., Blasi, F., Centanni, S., et al. Acute exacerbations of asthma in adults: role of Chlamydia pneumoniae infection. Eur Respir J 7:12 (1994), 2165–2168.
    • (1994) Eur Respir J , vol.7 , Issue.12 , pp. 2165-2168
    • Allegra, L.1    Blasi, F.2    Centanni, S.3
  • 133
    • 0033972782 scopus 로고    scopus 로고
    • Serological evidence of infection with Chlamydia pneumoniae is related to the severity of asthma
    • 133 Black, P.N., Scicchitano, R., Jenkins, C.R., et al. Serological evidence of infection with Chlamydia pneumoniae is related to the severity of asthma. Eur Respir J 15:2 (2000), 254–259.
    • (2000) Eur Respir J , vol.15 , Issue.2 , pp. 254-259
    • Black, P.N.1    Scicchitano, R.2    Jenkins, C.R.3
  • 134
    • 0034904704 scopus 로고    scopus 로고
    • Host immune response to Chlamydia pneumoniae heat shock protein 60 is associated with asthma
    • 134 Huittinen, T., Hahn, D., Anttila, T., et al. Host immune response to Chlamydia pneumoniae heat shock protein 60 is associated with asthma. Eur Respir J 17:6 (2001), 1078–1082.
    • (2001) Eur Respir J , vol.17 , Issue.6 , pp. 1078-1082
    • Huittinen, T.1    Hahn, D.2    Anttila, T.3
  • 135
    • 57449087457 scopus 로고    scopus 로고
    • Airflow limitation, asthma, and Chlamydia pneumoniae-specific heat shock protein 60
    • 135 Hahn, D.L., Peeling, R.W., Airflow limitation, asthma, and Chlamydia pneumoniae-specific heat shock protein 60. Ann Allergy Asthma Immunol 101:6 (2008), 614–618.
    • (2008) Ann Allergy Asthma Immunol , vol.101 , Issue.6 , pp. 614-618
    • Hahn, D.L.1    Peeling, R.W.2
  • 136
    • 27644482903 scopus 로고    scopus 로고
    • Chlamydophila (Chlamydia) pneumoniae serology and asthma in adults: a longitudinal analysis
    • 136 Pasternack, R., Huhtala, H., Karjalainen, J., Chlamydophila (Chlamydia) pneumoniae serology and asthma in adults: a longitudinal analysis. J Allergy Clin Immunol 116:5 (2005), 1123–1128.
    • (2005) J Allergy Clin Immunol , vol.116 , Issue.5 , pp. 1123-1128
    • Pasternack, R.1    Huhtala, H.2    Karjalainen, J.3
  • 137
    • 0036279989 scopus 로고    scopus 로고
    • Mycoplasma pneumoniae and Chlamydia pneumoniae in asthma: effect of clarithromycin
    • 137 Kraft, M., Cassell, G.H., Pak, J., et al. Mycoplasma pneumoniae and Chlamydia pneumoniae in asthma: effect of clarithromycin. Chest 121:6 (2002), 1782–1788.
    • (2002) Chest , vol.121 , Issue.6 , pp. 1782-1788
    • Kraft, M.1    Cassell, G.H.2    Pak, J.3
  • 138
    • 0035881144 scopus 로고    scopus 로고
    • Trial of roxithromycin in subjects with asthma and serological evidence of infection with Chlamydia pneumoniae
    • 138 Black, P.N., Blasi, F., Jenkins, C.R., et al. Trial of roxithromycin in subjects with asthma and serological evidence of infection with Chlamydia pneumoniae. Am J Respir Crit Care Med 164:4 (2001), 536–541.
    • (2001) Am J Respir Crit Care Med , vol.164 , Issue.4 , pp. 536-541
    • Black, P.N.1    Blasi, F.2    Jenkins, C.R.3
  • 139
    • 0028856927 scopus 로고
    • Treatment of Chlamydia pneumoniae infection in adult asthma: a before-after trial
    • 139 Hahn, D.L., Treatment of Chlamydia pneumoniae infection in adult asthma: a before-after trial. J Fam Pract 41:4 (1995), 345–351.
    • (1995) J Fam Pract , vol.41 , Issue.4 , pp. 345-351
    • Hahn, D.L.1
  • 140
    • 77957795745 scopus 로고    scopus 로고
    • A trial of clarithromycin for the treatment of suboptimally controlled asthma
    • 140 Sutherland, E.R., King, T.S., Icitovic, N., et al. A trial of clarithromycin for the treatment of suboptimally controlled asthma. J Allergy Clin Immunol 126:4 (2010), 747–753.
    • (2010) J Allergy Clin Immunol , vol.126 , Issue.4 , pp. 747-753
    • Sutherland, E.R.1    King, T.S.2    Icitovic, N.3
  • 141
    • 0028244144 scopus 로고
    • The association of Chlamydia pneumoniae infection and reactive airway disease in children
    • 141 Emre, U., Roblin, P.M., Gelling, M., et al. The association of Chlamydia pneumoniae infection and reactive airway disease in children. Arch Pediatr Adolesc Med 148:7 (1994), 727–732.
    • (1994) Arch Pediatr Adolesc Med , vol.148 , Issue.7 , pp. 727-732
    • Emre, U.1    Roblin, P.M.2    Gelling, M.3
  • 142
    • 33645791946 scopus 로고    scopus 로고
    • The effect of telithromycin in acute exacerbations of asthma
    • 142 Johnston, S.L., Blasi, F., Black, P.N., et al. The effect of telithromycin in acute exacerbations of asthma. N Engl J Med 354:15 (2006), 1589–1600.
    • (2006) N Engl J Med , vol.354 , Issue.15 , pp. 1589-1600
    • Johnston, S.L.1    Blasi, F.2    Black, P.N.3


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