메뉴 건너뛰기




Volumn 68, Issue 10, 2013, Pages 2363-2368

Doxycycline suppresses Chlamydia pneumoniae-mediated increases in ongoing immunoglobulin E and interleukin-4 responses by peripheral blood mononuclear cells of patients with allergic asthma

Author keywords

Cytokines; Immunomodulation; Inflammation; Tetracyclines

Indexed keywords

DOXYCYCLINE; GAMMA INTERFERON; IMMUNOGLOBULIN E; INTERLEUKIN 4;

EID: 84888808366     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dkt179     Document Type: Article
Times cited : (18)

References (41)
  • 1
    • 0028244144 scopus 로고
    • The association of Chlamydia pneumoniae infection and reactive airway disease in children
    • Emre U, Roblin PM, Gelling M et al. The association of Chlamydia pneumoniae infection and reactive airway disease in children. Arch Pediatr Adolesc Med 1994; 148: 727-31.
    • (1994) Arch Pediatr Adolesc Med , vol.148 , pp. 727-731
    • Emre, U.1    Roblin, P.M.2    Gelling, M.3
  • 2
    • 8644237367 scopus 로고    scopus 로고
    • Increased frequency of detection of Chlamydophila pneumoniae in asthma
    • Biscione GL, Corne J, Chauhan AJ et al. Increased frequency of detection of Chlamydophila pneumoniae in asthma. Eur Resp J 2004; 24: 745-9.
    • (2004) Eur Resp J , vol.24 , pp. 745-749
    • Biscione, G.L.1    Corne, J.2    Chauhan, A.J.3
  • 3
    • 0026599494 scopus 로고
    • Persistent infection with Chlamydia pneumoniae following acute respiratory illness
    • Hammerschlag MR, Chirgwin K, Roblin PM et al. Persistent infection with Chlamydia pneumoniae following acute respiratory illness. Clin Infect Dis 1992; 14: 178-82.
    • (1992) Clin Infect Dis , vol.14 , pp. 178-182
    • Hammerschlag, M.R.1    Chirgwin, K.2    Roblin, P.M.3
  • 4
    • 0035034606 scopus 로고    scopus 로고
    • A link between chronic asthma and chronic infection
    • Martin RJ, Kraft M, Chu HW et al. A link between chronic asthma and chronic infection. J Allergy Clin Immunol 2001; 107: 595-601.
    • (2001) J Allergy Clin Immunol , vol.107 , pp. 595-601
    • Martin, R.J.1    Kraft, M.2    Chu, H.W.3
  • 5
    • 0029054981 scopus 로고
    • Detection of anti-Chlamydia pneumoniae IgE in children with reactive airway disease
    • Emre U, Sokolovskaya N, Roblin PM et al. Detection of anti-Chlamydia pneumoniae IgE in children with reactive airway disease. J Infect Dis 1995; 172: 265-7.
    • (1995) J Infect Dis , vol.172 , pp. 265-267
    • Emre, U.1    Sokolovskaya, N.2    Roblin, P.M.3
  • 6
    • 29744465421 scopus 로고    scopus 로고
    • Chlamydophila pneumoniae and Mycoplasma pneumoniae. A role in asthma pathogenesis?
    • Johnston SL, Martin RJ. Chlamydophila pneumoniae and Mycoplasma pneumoniae. A role in asthma pathogenesis? Am J Respir Crit Care Med 2005; 172: 1078-89.
    • (2005) Am J Respir Crit Care Med , vol.172 , pp. 1078-1089
    • Johnston, S.L.1    Martin, R.J.2
  • 7
    • 33645791946 scopus 로고    scopus 로고
    • The effect of telithromycin in acute exacerbations of asthma
    • Johnston SL, Blasi F, Black PN et al. The effect of telithromycin in acute exacerbations of asthma. N Engl J Med 2006; 354: 1589-600.
    • (2006) N Engl J Med , vol.354 , pp. 1589-1600
    • Johnston, S.L.1    Blasi, F.2    Black, P.N.3
  • 9
    • 84857335625 scopus 로고    scopus 로고
    • Chlamydial infections and chronic diseases
    • In: Fratamico PM, Smith JL, Brogden KA, eds. Post-Infectious Sequelae and Long-Term Consequences of Infectious Diseases. Washington, DC: American Society for Microbiology Press
    • Hammerschlag MR, Kohlhoff SA, Darville T. Chlamydial infections and chronic diseases. In: Fratamico PM, Smith JL, Brogden KA, eds. Post-Infectious Sequelae and Long-Term Consequences of Infectious Diseases. Washington, DC: American Society for Microbiology Press, 2008; 27-52.
    • (2008) , pp. 27-52
    • Hammerschlag, M.R.1    Kohlhoff, S.A.2    Darville, T.3
  • 10
    • 46649085640 scopus 로고    scopus 로고
    • Minocycline treatment results in reduced oral steroid requirements in adults
    • Daoud A, Gloria CJ, Taningco G et al. Minocycline treatment results in reduced oral steroid requirements in adults. Asthma. Allergy Asthma Proc 2008; 29: 286-94.
    • (2008) Asthma. Allergy Asthma Proc , vol.29 , pp. 286-294
    • Daoud, A.1    Gloria, C.J.2    Taningco, G.3
  • 12
    • 0021677785 scopus 로고
    • Tetracyclines inhibit tissue collagenase activity. A new mechanism in the treatment of periodontal disease
    • Golub L, Ramamurthy N, McNamara T et al. Tetracyclines inhibit tissue collagenase activity. A new mechanism in the treatment of periodontal disease. J Periodontal Res 1984; 19: 651-5.
    • (1984) J Periodontal Res , vol.19 , pp. 651-655
    • Golub, L.1    Ramamurthy, N.2    McNamara, T.3
  • 13
    • 79251607712 scopus 로고    scopus 로고
    • Clinical applications of non-antimicrobial tetracyclines in dermatology
    • Monk E, Shalita A, Siegel DM. Clinical applications of non-antimicrobial tetracyclines in dermatology. Pharmacol Res 2011; 63: 130-45.
    • (2011) Pharmacol Res , vol.63 , pp. 130-145
    • Monk, E.1    Shalita, A.2    Siegel, D.M.3
  • 15
    • 84888802780 scopus 로고    scopus 로고
    • Peripheral blood mononuclear cells (PBMC) in allergic asthmatics with serologic evidence of prior Chlamydia pneumoniae (Cpn) infection contain activated cells that continue to secrete IgE ex vivo
    • Abstract 648
    • Kohlhoff SA, Dzhindzhikhashvili M, Smith-Norowitz T et al. Peripheral blood mononuclear cells (PBMC) in allergic asthmatics with serologic evidence of prior Chlamydia pneumoniae (Cpn) infection contain activated cells that continue to secrete IgE ex vivo. J Allergy Clin Immunol 2009; 123 Suppl: S170, Abstract 648.
    • (2009) J Allergy Clin Immunol , vol.123 , Issue.SUPPL.
    • Kohlhoff, S.A.1    Dzhindzhikhashvili, M.2    Smith-Norowitz, T.3
  • 16
    • 36348929624 scopus 로고    scopus 로고
    • Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma
    • National Heart, Lung, and Blood Institute, and National Asthma Education and Prevention Program, 8 March 2013, date last accessed
    • National Heart, Lung, and Blood Institute, and National Asthma Education and Prevention Program. Expert Panel Report 3: Guidelines for the Diagnosis and Management of Asthma, 2007; 40-3. http://www.nhlbi. nih.gov/guidelines/asthma/asthgdln.pdf (8 March 2013, date last accessed).
    • (2007) , pp. 40-3
  • 17
    • 33748799413 scopus 로고    scopus 로고
    • Guidelines for the use of antibiotics in acute upper respiratory tract infections
    • Wong DM, Blumberg DA, Lowe LG. Guidelines for the use of antibiotics in acute upper respiratory tract infections. Am Fam Physician 2006; 74: 956-66.
    • (2006) Am Fam Physician , vol.74 , pp. 956-966
    • Wong, D.M.1    Blumberg, D.A.2    Lowe, L.G.3
  • 18
    • 0026623438 scopus 로고
    • Use of HEp-2 cells for improved isolation and passage of Chlamydia pneumoniae
    • Roblin PM, Dumornay W, Hammerschlag MR. Use of HEp-2 cells for improved isolation and passage of Chlamydia pneumoniae. J Clin Microbiol 1992; 30: 1968-71.
    • (1992) J Clin Microbiol , vol.30 , pp. 1968-1971
    • Roblin, P.M.1    Dumornay, W.2    Hammerschlag, M.R.3
  • 19
    • 0037316663 scopus 로고    scopus 로고
    • Comparison of a new quantitative ompA-based real-time PCR TaqMan assay for detection of Chlamydia pneumoniae DNA in respiratory specimens with four conventional PCR assays
    • Apfalter P, Barousch W, Nehr M et al. Comparison of a new quantitative ompA-based real-time PCR TaqMan assay for detection of Chlamydia pneumoniae DNA in respiratory specimens with four conventional PCR assays. J Clin Microbiol 2003; 41: 592-600.
    • (2003) J Clin Microbiol , vol.41 , pp. 592-600
    • Apfalter, P.1    Barousch, W.2    Nehr, M.3
  • 20
    • 0035056342 scopus 로고    scopus 로고
    • Development of a genomics-based PCR assay for detection of Mycoplasma pneumoniae in a large outbreak in New York State
    • Waring AL, Halse TA, Csiza CK et al. Development of a genomics-based PCR assay for detection of Mycoplasma pneumoniae in a large outbreak in New York State. J Clin Microbiol 2001; 39: 1385-90.
    • (2001) J Clin Microbiol , vol.39 , pp. 1385-1390
    • Waring, A.L.1    Halse, T.A.2    Csiza, C.K.3
  • 21
    • 0036199247 scopus 로고    scopus 로고
    • Role of persistent infection in the control and severity of asthma: focus on Chlamydia pneumoniae
    • von Hertzen LC. Role of persistent infection in the control and severity of asthma: focus on Chlamydia pneumoniae. Eur Respir J 2002; 19: 546-56.
    • (2002) Eur Respir J , vol.19 , pp. 546-556
    • von Hertzen, L.C.1
  • 22
    • 77950261975 scopus 로고    scopus 로고
    • Howare TH2-type responses initiated and amplified?
    • Paul WE, Zhu J. Howare TH2-type responses initiated and amplified? Nat Rev Immunol 2010; 10: 225-35.
    • (2010) Nat Rev Immunol , vol.10 , pp. 225-235
    • Paul, W.E.1    Zhu, J.2
  • 23
    • 0034442276 scopus 로고    scopus 로고
    • Cell-mediated immune response during primary Chlamydia pneumoniae infection
    • Halme S, Latvala J, Karttunen R et al. Cell-mediated immune response during primary Chlamydia pneumoniae infection. Infect Immun 2000; 68: 7156-8.
    • (2000) Infect Immun , vol.68 , pp. 7156-7158
    • Halme, S.1    Latvala, J.2    Karttunen, R.3
  • 24
    • 0032751041 scopus 로고    scopus 로고
    • IFN-g knockout mice show Th2-associated delayed-type hypersensitivity and the inflammatory cells fail to localize and control chlamydial infection
    • Wang S, Fan Y, Brunham RC et al. IFN-g knockout mice show Th2-associated delayed-type hypersensitivity and the inflammatory cells fail to localize and control chlamydial infection. Eur J Immunol 1999; 29: 3782-92.
    • (1999) Eur J Immunol , vol.29 , pp. 3782-3792
    • Wang, S.1    Fan, Y.2    Brunham, R.C.3
  • 26
    • 77957795745 scopus 로고    scopus 로고
    • A trial of clarithromycin for the treatment of suboptimally controlled asthma
    • Sutherland ER, King TS, Icitovic N et al. A trial of clarithromycin for the treatment of suboptimally controlled asthma. J Allergy Clin Immunol 2010; 126: 747-53.
    • (2010) J Allergy Clin Immunol , vol.126 , pp. 747-753
    • Sutherland, E.R.1    King, T.S.2    Icitovic, N.3
  • 27
    • 27744585664 scopus 로고    scopus 로고
    • Safety of doxycycline and minocycline: a systematic review
    • Smith K, Leyden JJ. Safety of doxycycline and minocycline: a systematic review. Clin Ther 2005; 27: 1329-42.
    • (2005) Clin Ther , vol.27 , pp. 1329-1342
    • Smith, K.1    Leyden, J.J.2
  • 28
    • 80054114660 scopus 로고    scopus 로고
    • Non-antibiotic properties of tetracyclines as anti-allergy and asthma drugs
    • Joks R, Durkin H. Non-antibiotic properties of tetracyclines as anti-allergy and asthma drugs. Pharmacol Res 2011; 64: 602-9.
    • (2011) Pharmacol Res , vol.64 , pp. 602-609
    • Joks, R.1    Durkin, H.2
  • 29
    • 0034919755 scopus 로고    scopus 로고
    • Tetracyclines inhibit activated B cell function
    • Kuzin II, Snyder JE, Ugine GD et al. Tetracyclines inhibit activated B cell function. Int Immunol 2001; 13: 921-31.
    • (2001) Int Immunol , vol.13 , pp. 921-931
    • Kuzin, I.I.1    Snyder, J.E.2    Ugine, G.D.3
  • 30
    • 0018861330 scopus 로고
    • Effect of tetracycline treatment on immunological responses in mice
    • Thong YH, Ferrante A. Effect of tetracycline treatment on immunological responses in mice. Clin Exp Immunol 1980; 39: 728-32.
    • (1980) Clin Exp Immunol , vol.39 , pp. 728-732
    • Thong, Y.H.1    Ferrante, A.2
  • 31
    • 0025808642 scopus 로고
    • The effects of minocycline and tetracycline on the mitotic response of human peripheral blood lymphocytes
    • Ingham E, Turnbull L, Kearney JN. The effects of minocycline and tetracycline on the mitotic response of human peripheral blood lymphocytes. J Antimicrob Chemother 1991; 27: 607-17.
    • (1991) J Antimicrob Chemother , vol.27 , pp. 607-617
    • Ingham, E.1    Turnbull, L.2    Kearney, J.N.3
  • 32
    • 0034063151 scopus 로고    scopus 로고
    • Roles of interleukin-12 and gamma interferon in murine Chlamydia pneumoniae infection
    • Geng Y, Berencsi K, Gyulai Z et al. Roles of interleukin-12 and gamma interferon in murine Chlamydia pneumoniae infection. Infect Immun 2000; 68: 2245-53.
    • (2000) Infect Immun , vol.68 , pp. 2245-2253
    • Geng, Y.1    Berencsi, K.2    Gyulai, Z.3
  • 33
    • 0344299221 scopus 로고    scopus 로고
    • Role of innate and adaptive immunity in the outcome of primary infection with Chlamydia pneumoniae, as analyzed in genetically modified mice
    • Rottenberg ME, Gigliotti Rothfuchs AC et al. Role of innate and adaptive immunity in the outcome of primary infection with Chlamydia pneumoniae, as analyzed in genetically modified mice. J Immunol 1999; 162: 2829-36.
    • (1999) J Immunol , vol.162 , pp. 2829-2836
    • Rottenberg, M.E.1    Gigliotti Rothfuchs, A.C.2
  • 34
    • 23344432885 scopus 로고    scopus 로고
    • Degradation of Chlamydia pneumoniae by peripheral blood monocytic cells
    • Hackstadt
    • Wolf K, Fischer E, Hackstadt. Degradation of Chlamydia pneumoniae by peripheral blood monocytic cells. Infect Immun 2005; 73: 4560-70.
    • (2005) Infect Immun , vol.73 , pp. 4560-4570
    • Wolf, K.1    Fischer, E.2
  • 35
    • 0028303743 scopus 로고
    • Susceptibilities of clarithromycin and erythromycin of isolates of Chlamydia pneumoniae from children with pneumonia
    • Roblin PM, Montalban G, Hammerschlag MR. Susceptibilities of clarithromycin and erythromycin of isolates of Chlamydia pneumoniae from children with pneumonia. Antimicrob Agents Chemother 1994; 38: 1588-9.
    • (1994) Antimicrob Agents Chemother , vol.38 , pp. 1588-1589
    • Roblin, P.M.1    Montalban, G.2    Hammerschlag, M.R.3
  • 36
    • 73149115293 scopus 로고    scopus 로고
    • Quantification of Chlamydia pneumoniae in cultured human macrophages and HL cells: comparison of real-time PCR, immunofluorescence and ELISA methods
    • Poikonen K, Lajunen T, Silvennoinen-Kassinen S et al. Quantification of Chlamydia pneumoniae in cultured human macrophages and HL cells: comparison of real-time PCR, immunofluorescence and ELISA methods. APMIS 2010; 118: 45-8.
    • (2010) APMIS , vol.118 , pp. 45-48
    • Poikonen, K.1    Lajunen, T.2    Silvennoinen-Kassinen, S.3
  • 37
    • 0017234905 scopus 로고
    • Doxycycline in serum and bronchial secretions
    • Hartnett BJS, Marlin GE. Doxycycline in serum and bronchial secretions. Thorax 1976; 31: 144-8.
    • (1976) Thorax , vol.31 , pp. 144-148
    • Hartnett, B.J.S.1    Marlin, G.E.2
  • 38
    • 0033843634 scopus 로고    scopus 로고
    • In vitro activity of GAR-936 against Chlamydia pneumoniae and Chlamydia trachomatis
    • Roblin PM, Hammerschlag MR. In vitro activity of GAR-936 against Chlamydia pneumoniae and Chlamydia trachomatis. Int J Antimicrob Agents 2000; 16: 61-3.
    • (2000) Int J Antimicrob Agents , vol.16 , pp. 61-63
    • Roblin, P.M.1    Hammerschlag, M.R.2
  • 39
    • 0037388301 scopus 로고    scopus 로고
    • Effects of subantimicrobial-dose doxycycline in the treatment of moderate acne
    • Skidmore R, Kovach R, Walker C et al. Effects of subantimicrobial-dose doxycycline in the treatment of moderate acne. Arch Dermatol 2003; 139: 459-64.
    • (2003) Arch Dermatol , vol.139 , pp. 459-464
    • Skidmore, R.1    Kovach, R.2    Walker, C.3
  • 40
    • 0028394707 scopus 로고
    • Spontaneous IgE production in asthmatic children
    • Mukouyama T, Ito W, Ichikawa K et al. Spontaneous IgE production in asthmatic children. Arerugi 1994; 43: 474-81.
    • (1994) Arerugi , vol.43 , pp. 474-481
    • Mukouyama, T.1    Ito, W.2    Ichikawa, K.3
  • 41
    • 0032975213 scopus 로고    scopus 로고
    • Chlamydiapneumoniae infection in human monocytes
    • Airenne S, Surcel HM, Alakarppa H et al. Chlamydiapneumoniae infection in human monocytes. Infect Immun 1999; 67: 1445-9.
    • (1999) Infect Immun , vol.67 , pp. 1445-1449
    • Airenne, S.1    Surcel, H.M.2    Alakarppa, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.