Anti-inflammatory effect of roxithromycin in patients with aspirin- intolerant asthma

Clinical and Experimental Allergy

Volumn 29, Issue 7, 1999, Pages 950-956

  Shoji, T ^a,b   Yoshida, S ^c,d   Sakamoto, H ^c,d   Hasegawa, H ^c   Nakagawa, H ^c   Amayasu, H ^c  

^a Takatsu General Hospital   (Japan)

^b SHOWA UNIVERSITY FUJIGAOKA HOSPITAL   (Japan)

^c AOKI International Medical Center   (Japan)

^d FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Aspirin intolerant asthma; Bronchial hyperresponsiveness; Bronchial inflammation; Eosinophils; Roxithromycin

Indexed keywords

ACETYLSALICYLIC ACID; DIPYRONE; EOSINOPHIL CATIONIC PROTEIN; LEUKOTRIENE E4; MACROLIDE; PEPTIDOLEUKOTRIENE; PLACEBO; ROXITHROMYCIN;

ADULT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTHMA; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG HYPERSENSITIVITY; EOSINOPHILIA; FEMALE; HUMAN; INFLAMMATION; MALE; PRIORITY JOURNAL; PROVOCATION TEST; RANDOMIZED CONTROLLED TRIAL;

ADULT; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ASPIRIN; ASTHMA; BLOOD PROTEINS; BRONCHIAL HYPERREACTIVITY; BRONCHIAL PROVOCATION TESTS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CROSS-OVER STUDIES; DIPYRONE; DOUBLE-BLIND METHOD; EOSINOPHIL GRANULE PROTEINS; EOSINOPHILS; FEMALE; HUMANS; LEUKOTRIENE E4; MALE; MIDDLE AGED; RIBONUCLEASES; ROXITHROMYCIN;

EID: 0032980088     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2222.1999.00551.x     Document Type: Article

References (23)

1. McDonald JR, Mathison DA, Stevenson DD. Aspirin intolerance in asthma. Detection by oral challenge. J Allergy Clin Immunol 1972:50:198-207.
2. Delaney JC. The diagnosis of aspirin idiosyncrasy by analgesic challenge. Clin Allergy 1976; 6:177-81.
3. Spector SL, Wangaard CH, Farr RS. Aspirin and concomitant idiosynerasies in adult asthmatic patients. J Allergy Cin Immunol 1979; 64:500-6.
4. Houjou S, Dobashi K, Nakazawa T. Aspirin-induced asthma. Jpn J Clin Med 1994; 3:355-8.
5. Power I. Aspirin-induced asthma. Br J Anaesth 1993; 71: 619-21.
6. Szczeklik A, Schmitz SM. Aspirin-induced asthma: from pathogenesis to therapy. Allergol Immunopathol 1993; 21:35-40.
7. Szczeklik A, Sladak K, Dworski R, Nizankowska E, Soja J, Sheller J. Bronchial aspirin challenge causes specific eicosanoid response in aspirin-sensitive asthmatics. Am J Respir Crit Care Med 1996; 154:1608-14.
8. 2 after aspirin challenge supports mast cell activation in aspirin-induced airway obstruction. J Allergy Clin Immunol 1996; 98:421-32.
9. Miyatake H, Taki F, Taniguchi H, Suzuki R, Takagi K, Satake T. Erythromycin reduces the severity of bronchial hyperresponsiveness in asthma. Chest 1991; 99:670-3.
10. American Thoracic Society. Standards for the diagnosis and care of patients with chronic obstructive pulmonary diseases (COPD) and asthma. Am Rev Respir Dis 1987; 136:225-44.
11. Popov T, Gottschalk AR, Kilendowicz R, Dolovich J, Poweres P, Hargreave FE. The elevation of a cell dispersion method of sputum examination. Clin Exp Allergy 1994; 24:778-83.
12. Szczeclik A, Gryglewski RJ, Czerniawska-Mysik G. Relationship of inhibition of prostaglandin biosynthesis by analgesics to asthma attacks in aspirin-sensitive patients. Br Med J 1975; 1:67-9.
13. Makino S, Kobayashi S, Miyamoto T, Shida T, Takahashi S. Standard for allergen bronchial provocation tests in asthma and hypcrscnsitivity pneumonitis. Jpn J Allergy 1982; 31: 1074-6.
14. 4. Prostaglandins 1994; 47:281-92.
15. Oosaki R, Mizushima Y, Kashii T, Kawasaki A, Kobayashi M. Therapeutic effect of pranlukast, a selective cycteinyl leukotriene receptor antagonist, on bronchial asthma. Int Arch Allegy Immunol 1996; 114:97-100.
16. Cowburn AS, Sladek K, Soja J et al. Overexpression of leukotriene C4 synthase in bronchial biopsies from patients with aspirin-intolerant asthma. Clin Invest 1998; 101:834-46.
17. 4 during aspirin-induced asthma. J Lab Clin Med 1992; 119:48-51.
18. 4 excretion in aspirin-induced asthma. Ann Allergy Asthma Immunol 1998; 80:171-6.
19. Chapman ID, Foster A, Morley J. The relationship between inflammation and hyperreactivity of the airways in asthma. Clin Exp Allergy 1993; 23:168-71.
20. Nasser SMS, Christie PH, Pfister R et al. Effect of endobrochial challenge on inflammatory cell populations in bronchial biopsies from aspirin-sensitive asthmatic subjects. Thorax 1996; 51:64-70.
21. Niimi A, Amitani R, Suzuki K, Tanaka E, Murayama T, Kuzc F. Serum eosinophil cationic protein as a marker of eosinophilic inflammation in asthma. Clin Exp Allergy 1998; 28:233-40.
22. Adachi T, Motojima S, Hirata A et al. Eosinophil apoptosis caused by theophylline, glucocorticoids, and macrolides after Stimulation with IL-5. J Allergy Clin Immunol 1996; 98: S207-15.
23. Konno S, Asano K, Kurokawa M, Ikeda K, Okamoto K, Adachi M. Antiasthmatic activity of a macrolide antibiotic, roxithromycin: analysis of possible mechanism in vitro and in vivo. Int Arch Allergy Immunol 1994; 105:308-16.