The airway microbiome in patients with severe asthma: Associations with disease features and severity

Journal of Allergy and Clinical Immunology

Volumn 136, Issue 4, 2015, Pages 874-884

  Huang, Yvonne J ^a   Nariya, Snehal ^b   Harris, Jeffrey M ^c   Lynch, Susan V ^b   Choy, David F ^c   Arron, Joseph R ^c   Boushey, Homer ^b  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c GENENTECH INC   (United States)

Author keywords

16S ribosomal RNA; asthma control; body mass index; inflammation; lung; Microbiota; steroids; TH2

Indexed keywords

BECLOMETASONE; CXCL1 CHEMOKINE; CXCL2 CHEMOKINE; CXCL3 CHEMOKINE; FK 506 BINDING PROTEIN; FLUTICASONE PROPIONATE; INTERLEUKIN 17; INTERLEUKIN 17F; INTERLEUKIN 8; RNA 16S; CORTICOSTEROID; TACROLIMUS BINDING PROTEIN 5;

ADULT; ARTICLE; ASTHMA; BACTERIAL FLORA; BODY MASS; BRONCHIAL FLORA; BRONCHUS; BRONCHUS BIOPSY; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; EOSINOPHIL COUNT; FEMALE; FORCED EXPIRATORY VOLUME; GENE EXPRESSION; HAEMOPHILUS INFLUENZAE; HUMAN; KLEBSIELLA; LACHNOSPIRACEAE; LEUKOCYTE COUNT; LOW DRUG DOSE; MALE; METAGENOMICS; MICROBIAL COMMUNITY; MICROBIOME; MICROFLORA; MYCOPLASMATACEAE; NONHUMAN; PREVOTELLA; PREVOTELLACEAE; PRIORITY JOURNAL; SPUTUM ANALYSIS; TH17 CELL; TH2 CELL; TREPONEMA; DISEASE COURSE; DYSBIOSIS; EOSINOPHIL; GENETICS; IMMUNOLOGY; INHALATIONAL DRUG ADMINISTRATION; LEUKOCYTE; METABOLISM; MICROBIOLOGY; MIDDLE AGED; RESPIRATORY MUCOSA; RESPIRATORY SYSTEM; SEVERITY OF ILLNESS INDEX; YOUNG ADULT;

ADMINISTRATION, INHALATION; ADRENAL CORTEX HORMONES; ADULT; ASTHMA; DISEASE PROGRESSION; DYSBIOSIS; EOSINOPHILS; FEMALE; HUMANS; KLEBSIELLA; LEUKOCYTES; MALE; MICROBIOTA; MIDDLE AGED; RESPIRATORY MUCOSA; RESPIRATORY SYSTEM; SEVERITY OF ILLNESS INDEX; TACROLIMUS BINDING PROTEINS; TH17 CELLS; YOUNG ADULT;

EID: 84943456033     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2015.05.044     Document Type: Article

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