Chlamydia pneumoniae harness host NLRP3 inflammasome-mediated caspase-1 activation for optimal intracellular growth in murine macrophages

Biochemical and Biophysical Research Communications

Volumn 452, Issue 3, 2014, Pages 689-694

  Itoh, Ryota ^a   Murakami, Issaku ^a   Chou, Bin ^a   Ishii, Kazunari ^a   Soejima, Toshinori ^a   Suzuki, Toshihiko ^b   Hiromatsu, Kenji ^a  

^a FUKUOKA UNIVERSITY   (Japan)

^b UNIVERSITY OF THE RYUKYUS   (Japan)

Author keywords

Caspase 1; Chlamydia pneumoniae; Inflammasome; Lipid droplet

Indexed keywords

CRYOPYRIN; FAT DROPLET; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; APOPTOSIS REGULATORY PROTEIN; CALCIUM BINDING PROTEIN; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; IPAF PROTEIN, MOUSE; PYCARD PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CELL DIVISION; CELL GROWTH; CHLAMYDIAL PNEUMONIA; CHLAMYDOPHILA PNEUMONIAE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; HOST; INNATE IMMUNITY; MOUSE; NONHUMAN; WILD TYPE; ANIMAL; BONE MARROW CELL; C57BL MOUSE; CELLULAR IMMUNITY; CHEMISTRY; DEFICIENCY; DRUG EFFECTS; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; KNOCKOUT MOUSE; MACROPHAGE; METABOLISM; MICROBIOLOGY; PHYSIOLOGY; PRIMARY CELL CULTURE; SECRETION (PROCESS); SIGNAL TRANSDUCTION; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; BIOLOGICAL TRANSPORT; BONE MARROW CELLS; CALCIUM-BINDING PROTEINS; CARRIER PROTEINS; CASPASE 1; CHLAMYDOPHILA PNEUMONIAE; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HOST-PATHOGEN INTERACTIONS; IMMUNITY, CELLULAR; IMMUNITY, INNATE; INFLAMMASOMES; INTERLEUKIN-1BETA; LIPID DROPLETS; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PRIMARY CELL CULTURE; SIGNAL TRANSDUCTION;

EID: 84907482558     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.08.128     Document Type: Article

References (34)

1. H.A. Saka, and R.H. Valdivia Acquisition of nutrients by Chlamydiae: unique challenges of living in an intracellular compartment Curr. Opin. Microbiol. 13 2010 4 10
2. C.A. Elwell, and J.N. Engel Lipid acquisition by intracellular Chlamydiae Cell. Microbiol. 14 2012 1010 1018
3. D. Heuer, A. Rejman Lipinski, N. Machuy, A. Karlas, A. Wehrens, F. Siedler, V. Brinkmann, and T.F. Meyer Chlamydia causes fragmentation of the Golgi compartment to ensure reproduction Nature 457 2009 731 735
4. J.L. Cocchiaro, Y. Kumar, E.R. Fischer, T. Hackstadt, and R.H. Valdivia Cytoplasmic lipid droplets are translocated into the lumen of the Chlamydia trachomatis parasitophorous vacuole Proc. Natl. Acad. Sci. U.S.A. 105 2008 9379 9384
5. R. Belland, D.M. Ojcius, and G.I. Byrne Chlamydia Nat. Rev. Microbiol. 2 2004 530 531
6. R.J. Belland, S.P. Ouellette, J. Gieffers, and G.I. Byrne Chlamydia pneumoniae and atherosclerosis Cell. Microbiol. 6 2004 117 127
7. L.A. Campbell, and C.C. Kuo Chlamydia pneumoniae - an infectious risk factor for atherosclerosis? Nat. Rev. Microbiol. 2 2004 23 32
8. H. Hu, G.N. Pierce, and G. Zhong The atherogenic effects of chlamydia are dependent on serum cholesterol and specific to Chlamydia pneumoniae J. Clin. Invest. 103 1999 747 753
9. F. Cao, A. Castrillo, P. Tontonoz, F. Re, and G.I. Byrne Chlamydia pneumoniae - induced macrophage foam cell formation is mediated by Toll-like receptor 2 Infect. Immun. 75 2007 753 759
10. S. Chen, R. Sorrentino, K. Shimada, Y. Bulut, T.M. Doherty, T.R. Crother, and M. Arditi Chlamydia pneumoniae-induced foam cell formation requires MyD88-dependent and -independent signaling and is reciprocally modulated by liver X receptor activation J. Immunol. 181 2008 7186 7193
11. E. Blessing, S. Nagano, L.A. Campbell, M.E. Rosenfeld, and C.C. Kuo Effect of Chlamydia trachomatis infection on atherosclerosis in apolipoprotein E-deficient mice Infect. Immun. 68 2000 7195 7197
12. B.K. Davis, H. Wen, and J.P. Ting The inflammasome NLRs in immunity, inflammation, and associated diseases Annu. Rev. Immunol. 29 2011 707 735
13. K. Schroder, and J. Tschopp The inflammasomes Cell 140 2010 821 832
14. C. Bryant, and K.A. Fitzgerald Molecular mechanisms involved in inflammasome activation Trends Cell Biol. 19 2009 455 464
15. V. Petrilli, S. Papin, C. Dostert, A. Mayor, F. Martinon, and J. Tschopp Activation of the NALP3 inflammasome is triggered by low intracellular potassium concentration Cell Death Differ. 14 2007 1583 1589
16. F. Martinon Signaling by ROS drives inflammasome activation Eur. J. Immunol. 40 2010 616 619
17. V. Hornung, F. Bauernfeind, A. Halle, E.O. Samstad, H. Kono, K.L. Rock, K.A. Fitzgerald, and E. Latz Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization Nat. Immunol. 9 2008 847 856
18. Y. Zhao, J. Yang, J. Shi, Y.-N. Gong, Q. Lu, H. Xu, L. Liu, and F. Shao The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus Nature 477 2011 596 600
19. E.M. Kofoed, and R.E. Vance Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity Nature 477 2011 592 595
20. T. Horng, and G.S. Hotamisligil Linking the inflammasome to obesity-related disease Nat. Med. 17 2011 164 165
21. D.V. Krysko, P. Agostinis, O. Krysko, A.D. Garg, C. Bachert, B.N. Lambrecht, and P. Vandenabeele Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation Trends Immunol. 32 2011 157 164
22. B. Vandanmagsar, Y.-H. Youm, A. Ravussin, J.E. Galgani, K. Stadler, R.L. Mynatt, E. Ravussin, J.M. Stephens, and V.D. Dixit The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance Nat. Med. 17 2011 179 188
23. P. Duewell, H. Kono, K.J. Rayner, C.M. Sirois, G. Vladimer, F.G. Bauernfeind, G.S. Abela, L. Franchi, G. Nuñez, M. Schnurr, T. Espevik, E. Lien, K.A. Fitzgerald, K.L. Rock, K.J. Moore, S.D. Wright, V. Hornung, and E. Latz NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals Nature 464 2010 1357 1361
24. R. Stienstra, J.A.V. Diepen, C.J. Tack, M.H. Zaki, F.L.V.D. Veerdonk, D. Perera, G.A. Neale, G.J. Hooiveld, A. Hijmans, I. Vroegrijk, S.V.D. Berg, J. Romijn, P.C.N. Rensen, L.A.B. Joosten, M.G. Netea, and T.-D. Kanneganti Inflammasome is a central player in the induction of obesity and insulin resistance Proc. Natl. Acad. Sci. U.S.A. 108 2011 15324 15329
25. D.D. Nardo, and E. Latz NLRP3 inflammasomes link inflammation and metabolic disease Trends Immunol. 32 2011 373 379
26. Y. Kumar, J. Cocchiaro, and R.H. Valdivia The obligate intracellular pathogen Chlamydia trachomatis targets host lipid droplets Curr. Biol. 16 2006 1646 1651
27. I.W. Fong, B. Chiu, E. Viira, M.W. Fong, D. Jang, and J. Mahony Rabbit model for Chlamydia pneumoniae infection J. Clin. Microbiol. 35 1997 48 52
28. M.D. de Kruif, E.C. van Gorp, T.T. Keller, J.M. Ossewaarde, and H. ten Cate Chlamydia pneumoniae infections in mouse models: relevance for atherosclerosis research Cardiovasc. Res. 65 2005 317 327
29. Y. Naiki, R. Sorrentino, M.H. Wong, K.S. Michelsen, K. Shimada, S. Chen, A. Yilmaz, A. Slepenkin, N.W. Schröder, T.R. Crother, Y. Bulut, T.M. Doherty, M. Bradley, Z. Shaposhnik, E.M. Peterson, P. Tontonoz, P.K. Shah, and M. Arditi TLR/MyD88 and liver X receptor alpha signaling pathways reciprocally control Chlamydia pneumoniae-induced acceleration of atherosclerosis J. Immunol. 181 2008 7176 7185
30. A.A. Abdul-Sater, E. Koo, G. Hacker, and D.M. Ojcius Inflammasome-dependent caspase-1 activation in cervical epithelial cells stimulates growth of the intracellular pathogen Chlamydia trachomatis J. Biol. Chem. 284 2009 26789 26796
31. X. He, S. Mekasha, N. Mavrogiorgos, K.A. Fitzgerald, E. Lien, and R.R. Ingalls Inflammation and fibrosis during Chlamydia pneumoniae infection is regulated by IL-1 and the NLRP3/ASC inflammasome J. Immunol. 184 2010 5743 5754
32. K. Shimada, T.R. Crother, J. Karlin, S. Chen, N. Chiba, V.K. Ramanujan, L. Vergnes, D.M. Ojcius, and M. Arditi Caspase-1 dependent IL-1β secretion is critical for host defense in a mouse model of Chlamydia pneumoniae lung infection PLoS ONE 6 2011 e21477
33. L. Gurcel, L. Abrami, S. Girardin, J. Tschopp, and F.G. van der Goot Caspase-1 activation of lipid metabolic pathways in response to bacterial pore-forming toxins promotes cell survival Cell 126 2006 1135 1145
34. N. Arpaia, J. Godec, L. Lau, K.E. Sivick, L.M. McLaughlin, M.B. Jones, T. Dracheva, S.N. Peterson, D.M. Monack, and G.M. Barton TLR signaling is required for Salmonella typhimurium virulence Cell 144 2011 675 688