Mycoplasma pneumoniae modulates STAT3-STAT6/EGFR-FOXA2 signaling to induce overexpression of airway mucins

Infection and Immunity

Volumn 82, Issue 12, 2014, Pages 5246-5255

  Hao, Yonghua ^a   Kuang, Zhizhou ^a   Jing, Jia ^a   Miao, Jinfeng ^b   Mei, Li Yu ^a   Lee, Ryan J ^a   Kim, Susie ^a   Choe, Shawn ^a   Krause, Duncan C ^c   Lau, Gee W ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b NANJING AGRICULTURAL UNIVERSITY   (China)

^c UNIVERSITY OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; HEPATOCYTE NUCLEAR FACTOR 3BETA; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 6; MUCIN 5AC; MUCIN 5B; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; STAT3 PROTEIN; STAT6 PROTEIN; EGFR PROTEIN, HUMAN; EGFR PROTEIN, MOUSE; FOXA2 PROTEIN, HUMAN; FOXA2 PROTEIN, MOUSE; MUC5AC PROTEIN, HUMAN; MUC5B PROTEIN, HUMAN; MUCIN; STAT3 PROTEIN, HUMAN; STAT3 PROTEIN, MOUSE; STAT6 PROTEIN, HUMAN; STAT6 PROTEIN, MOUSE;

AIRWAY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN ANTIBODY COMPLEX; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; CORRELATION ANALYSIS; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE SILENCING; GOBLET CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG FUNCTION; LUNG LAVAGE; MOUSE; MUCUS SECRETION; MYCOPLASMA PNEUMONIA; MYCOPLASMA PNEUMONIAE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY EPITHELIUM; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CELL CULTURE; DISEASE MODEL; EPITHELIUM CELL; GENE EXPRESSION PROFILING; HOST PATHOGEN INTERACTION; METABOLISM; MICROBIOLOGY; PATHOLOGY; PHYSIOLOGY; SECRETION (PROCESS);

ANIMALS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; GENE EXPRESSION PROFILING; HEPATOCYTE NUCLEAR FACTOR 3-BETA; HOST-PATHOGEN INTERACTIONS; HUMANS; MICE, INBRED C57BL; MUCIN 5AC; MUCIN-5B; MUCINS; MYCOPLASMA PNEUMONIAE; PNEUMONIA, MYCOPLASMA; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; STAT6 TRANSCRIPTION FACTOR;

EID: 84911373369     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.01989-14     Document Type: Article

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