Structure of CARDS toxin, a unique ADP-ribosylating and vacuolating cytotoxin from Mycoplasma pneumoniae

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 16, 2015, Pages 5165-5170

  Becker, Argentina ^a   Kannan, T R ^a   Taylor, Alexander B ^a,b   Pakhomova, Olga N ^a,c   Zhang, Yanfeng ^a   Somarajan, Sudha R ^a   Galaleldeen, Ahmad ^a,d   Holloway, Stephen P ^a   Baseman, Joel B ^a   Hart, P John ^a,b,e  

^a Mays Cancer Center at UT Health San Antonio   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c OLD DOMINION UNIVERSITY   (United States)

^d ST MARY'S UNIVERSITY   (United States)

^e SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

Author keywords

ADP ribosyltransferase; Mycoplasma cytotoxin; Reactive airway disease; Single crystal X ray diffraction; Vacuolation

Indexed keywords

BACTERIAL TOXIN; COMMUNITY ACQUIRED RESPIRATORY DISTRESS SYNDROME TOXIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHOSPHATIDYLCHOLINE; SPHINGOMYELIN; UNCLASSIFIED DRUG; VACUOLATING TOXIN; ADENOSINE DIPHOSPHATE RIBOSE; BACTERIAL PROTEIN; CARDS TOXIN, MYCOPLASMA PNEUMONIAE; CYTOTOXIN; DIPALMITOYLPHOSPHATIDYLCHOLINE;

ADENOSINE DIPHOSPHATE RIBOSYLATION; AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL VIRULENCE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELL SURFACE; CELL VACUOLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; INTERNALIZATION; MYCOPLASMA PNEUMONIA; MYCOPLASMA PNEUMONIAE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECONDARY STRUCTURE; STRUCTURE ACTIVITY RELATION; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYME ACTIVE SITE; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN TERTIARY STRUCTURE;

BACTERIA (MICROORGANISMS); LOTUS; MYCOPLASMA; MYCOPLASMA PNEUMONIAE;

1,2-DIPALMITOYLPHOSPHATIDYLCHOLINE; ADENOSINE DIPHOSPHATE RIBOSE; ADP RIBOSE TRANSFERASES; AMINO ACID SEQUENCE; BACTERIAL PROTEINS; BACTERIAL TOXINS; CATALYTIC DOMAIN; CYTOTOXINS; HUMANS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MYCOPLASMA PNEUMONIAE; PHOSPHATIDYLCHOLINES; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; SPHINGOMYELINS; STRUCTURE-ACTIVITY RELATIONSHIP; VACUOLES;

EID: 84928252347     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1420308112     Document Type: Article

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