Angiotensin II induces connective tissue growth factor and collagen i expression via transforming growth factor-β-dependent and -independent Smad pathways: The role of Smad3

Hypertension

Volumn 54, Issue 4, 2009, Pages 877-884

  Yang, Fuye ^a   Chung, Arthur C K ^b   Ru Huang, Xiao ^b   Lan, Hui Yao ^a,b  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Angiotensin II; CTGF; MAP kinases; Renal fibrosis; Smads; TGF

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; 2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; COLLAGEN TYPE 1; CONNECTIVE TISSUE GROWTH FACTOR; LOSARTAN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD7 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; TRANSFORMING GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GENE DELETION; HYPERTENSION; IN VITRO STUDY; KIDNEY DISEASE; KIDNEY EPITHELIUM; KIDNEY FIBROSIS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; UPREGULATION;

ANGIOTENSIN II; ANIMALS; CELL LINE; COLLAGEN TYPE I; CONNECTIVE TISSUE GROWTH FACTOR; DISEASE MODELS, ANIMAL; EPITHELIAL CELLS; HYPERTENSION; KIDNEY DISEASES; KIDNEY TUBULES; MALE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD7 PROTEIN; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION;

EID: 70349659185     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.109.136531     Document Type: Article

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