PPARγ ablation sensitizes proopiomelanocortin neurons to leptin during high-fat feeding

Journal of Clinical Investigation

Volumn 124, Issue 9, 2014, Pages 4017-4027

  Long, Lihong ^a,b   Toda, Chitoku ^a   Jeong, Jing Kwon ^a   Horvath, Tamas L ^a   Diano, Sabrina ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN; LEPTIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROOPIOMELANOCORTIN; REACTIVE OXYGEN METABOLITE; 2,4 THIAZOLIDINEDIONE DERIVATIVE; 2-CHLORO-5-NITROBENZANILIDE; ANILIDE; GLUCOSE; ROSIGLITAZONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CELL DENSITY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENERGY BALANCE; ENERGY EXPENDITURE; FAT INTAKE; FAT MASS; FEMALE; FOOD INTAKE; GLUCOSE METABOLISM; HORMONE SENSITIVITY; HYPERPHAGIA; INSULIN SENSITIVITY; LIPID DIET; LOCOMOTION; MALE; MITOCHONDRION; MOUSE; NERVE CELL; NONHUMAN; PEROXISOME; ANIMAL; DRUG EFFECTS; ENERGY METABOLISM; INSULIN RESISTANCE; METABOLISM; MOTOR ACTIVITY; PHYSIOLOGY;

ANILIDES; ANIMALS; DIET, HIGH-FAT; ENERGY METABOLISM; FEMALE; GLUCOSE; HYPERPHAGIA; INSULIN RESISTANCE; LEPTIN; MALE; MICE; MOTOR ACTIVITY; NEURONS; PPAR GAMMA; PRO-OPIOMELANOCORTIN; REACTIVE OXYGEN SPECIES; THIAZOLIDINEDIONES;

EID: 84907016676     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI76220     Document Type: Article

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