-
1
-
-
0037383806
-
Dynamic programming of CD8+ T lymphocyte responses
-
van Stipdonk M.J., et al. Dynamic programming of CD8+ T lymphocyte responses. Nature Immunology 2003, 4(4):361-365.
-
(2003)
Nature Immunology
, vol.4
, Issue.4
, pp. 361-365
-
-
van Stipdonk, M.J.1
-
2
-
-
0030803977
-
Nutrition and the immune system: an introduction
-
Chandra R.K. Nutrition and the immune system: an introduction. American Journal of Clinical Nutrition 1997, 66(2):460S-463S.
-
(1997)
American Journal of Clinical Nutrition
, vol.66
, Issue.2
-
-
Chandra, R.K.1
-
3
-
-
84865297442
-
The inflammation highway: metabolism accelerates inflammatory traffic in obesity
-
Johnson A.R., Justin Milner J., Makowski L. The inflammation highway: metabolism accelerates inflammatory traffic in obesity. Immunological Reviews 2012, 249(1):218-238.
-
(2012)
Immunological Reviews
, vol.249
, Issue.1
, pp. 218-238
-
-
Johnson, A.R.1
Justin Milner, J.2
Makowski, L.3
-
4
-
-
84865294186
-
The outliers become a stampede as immunometabolism reaches a tipping point
-
Nikolajczyk B.S., Jagannathan-Bogdan M., Denis G.V. The outliers become a stampede as immunometabolism reaches a tipping point. Immunological Reviews 2012, 249(1):253-275.
-
(2012)
Immunological Reviews
, vol.249
, Issue.1
, pp. 253-275
-
-
Nikolajczyk, B.S.1
Jagannathan-Bogdan, M.2
Denis, G.V.3
-
5
-
-
84874036703
-
In vivo T cell activation in lymphoid tissues is inhibited in the oxygen-poor microenvironment
-
Ohta A., et al. In vivo T cell activation in lymphoid tissues is inhibited in the oxygen-poor microenvironment. Frontiers in Immunology 2011, 2:27.
-
(2011)
Frontiers in Immunology
, vol.2
, pp. 27
-
-
Ohta, A.1
-
6
-
-
4344629204
-
Dynamic behavior of T cells and thymocytes in lymphoid organs as revealed by two-photon microscopy
-
Bousso P., Robey E.A. Dynamic behavior of T cells and thymocytes in lymphoid organs as revealed by two-photon microscopy. Immunity 2004, 21(3):349-355.
-
(2004)
Immunity
, vol.21
, Issue.3
, pp. 349-355
-
-
Bousso, P.1
Robey, E.A.2
-
7
-
-
0027474296
-
Metabolic changes in activated T cells: an NMR study of human peripheral blood lymphocytes
-
Bental M., Deutsch C. Metabolic changes in activated T cells: an NMR study of human peripheral blood lymphocytes. Magnetic Resonance in Medicine 1993, 29(3):317-326.
-
(1993)
Magnetic Resonance in Medicine
, vol.29
, Issue.3
, pp. 317-326
-
-
Bental, M.1
Deutsch, C.2
-
8
-
-
0036672918
-
Maintaining the norm: T-cell homeostasis
-
Jameson S.C. Maintaining the norm: T-cell homeostasis. Nature Reviews Immunology 2002, 2(8):547-556.
-
(2002)
Nature Reviews Immunology
, vol.2
, Issue.8
, pp. 547-556
-
-
Jameson, S.C.1
-
9
-
-
79960944880
-
Akt-dependent glucose metabolism promotes Mcl-1 synthesis to maintain cell survival and resistance to Bcl-2 inhibition
-
Coloff J.L., et al. Akt-dependent glucose metabolism promotes Mcl-1 synthesis to maintain cell survival and resistance to Bcl-2 inhibition. Cancer Research 2011, 71(15):5204-5213.
-
(2011)
Cancer Research
, vol.71
, Issue.15
, pp. 5204-5213
-
-
Coloff, J.L.1
-
10
-
-
79953157651
-
Akt requires glucose metabolism to suppress puma expression and prevent apoptosis of leukemic T cells
-
Coloff J.L., et al. Akt requires glucose metabolism to suppress puma expression and prevent apoptosis of leukemic T cells. Journal of Biological Chemistry 2011, 286(7):5921-5933.
-
(2011)
Journal of Biological Chemistry
, vol.286
, Issue.7
, pp. 5921-5933
-
-
Coloff, J.L.1
-
11
-
-
0035892899
-
IL-7 enhances the survival and maintains the size of naive T cells
-
Rathmell J.C., et al. IL-7 enhances the survival and maintains the size of naive T cells. Journal of Immunology 2001, 167(12):6869-6876.
-
(2001)
Journal of Immunology
, vol.167
, Issue.12
, pp. 6869-6876
-
-
Rathmell, J.C.1
-
12
-
-
0033635249
-
In the absence of extrinsic signals: nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability
-
Rathmell J.C., et al. In the absence of extrinsic signals: nutrient utilization by lymphocytes is insufficient to maintain either cell size or viability. Molecular Cell 2000, 6(3):683-692.
-
(2000)
Molecular Cell
, vol.6
, Issue.3
, pp. 683-692
-
-
Rathmell, J.C.1
-
13
-
-
41349093966
-
IL-7 promotes Glut1 trafficking and glucose uptake via STAT5-mediated activation of Akt to support T-cell survival
-
Wofford J.A., et al. IL-7 promotes Glut1 trafficking and glucose uptake via STAT5-mediated activation of Akt to support T-cell survival. Blood 2008, 111(4):2101-2111.
-
(2008)
Blood
, vol.111
, Issue.4
, pp. 2101-2111
-
-
Wofford, J.A.1
-
14
-
-
84864554409
-
The major isoforms of Bim contribute to distinct biological activities that govern the processes of autophagy and apoptosis in interleukin-7 dependent lymphocytes
-
Ruppert S.M., et al. The major isoforms of Bim contribute to distinct biological activities that govern the processes of autophagy and apoptosis in interleukin-7 dependent lymphocytes. Biochimica et Biophysica Acta 2012, 1823(10):1877-1893.
-
(2012)
Biochimica et Biophysica Acta
, vol.1823
, Issue.10
, pp. 1877-1893
-
-
Ruppert, S.M.1
-
15
-
-
15844386426
-
T cell homeostasis requires G protein-coupled receptor-mediated access to trophic signals that promote growth and inhibit chemotaxis
-
Cinalli R.M., et al. T cell homeostasis requires G protein-coupled receptor-mediated access to trophic signals that promote growth and inhibit chemotaxis. European Journal of Immunology 2005, 35(3):786-795.
-
(2005)
European Journal of Immunology
, vol.35
, Issue.3
, pp. 786-795
-
-
Cinalli, R.M.1
-
16
-
-
84864808073
-
Identification of IL-7-producing cells in primary and secondary lymphoid organs using IL-7-GFP knock-in mice
-
Hara T., et al. Identification of IL-7-producing cells in primary and secondary lymphoid organs using IL-7-GFP knock-in mice. Journal of Immunology 2012, 189(4):1577-1584.
-
(2012)
Journal of Immunology
, vol.189
, Issue.4
, pp. 1577-1584
-
-
Hara, T.1
-
17
-
-
77951639702
-
IL-7 is essential for homeostatic control of T cell metabolism in vivo
-
Jacobs S.R., Michalek R.D., Rathmell J.C. IL-7 is essential for homeostatic control of T cell metabolism in vivo. Journal of Immunology 2010, 184(7):3461-3469.
-
(2010)
Journal of Immunology
, vol.184
, Issue.7
, pp. 3461-3469
-
-
Jacobs, S.R.1
Michalek, R.D.2
Rathmell, J.C.3
-
18
-
-
44449165597
-
Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways
-
Jacobs S.R., et al. Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways. Journal of Immunology 2008, 180(7):4476-4486.
-
(2008)
Journal of Immunology
, vol.180
, Issue.7
, pp. 4476-4486
-
-
Jacobs, S.R.1
-
19
-
-
79953172571
-
Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets
-
Michalek R.D., et al. Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets. Journal of Immunology 2011, 186(6):3299-3303.
-
(2011)
Journal of Immunology
, vol.186
, Issue.6
, pp. 3299-3303
-
-
Michalek, R.D.1
-
20
-
-
34250179471
-
Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1
-
Zhao Y., et al. Glycogen synthase kinase 3alpha and 3beta mediate a glucose-sensitive antiapoptotic signaling pathway to stabilize Mcl-1. Molecular and Cellular Biology 2007, 27(12):4328-4339.
-
(2007)
Molecular and Cellular Biology
, vol.27
, Issue.12
, pp. 4328-4339
-
-
Zhao, Y.1
-
21
-
-
84863838332
-
Normal and cancer cell metabolism: lymphocytes and lymphoma
-
Altman B.J., Dang C.V. Normal and cancer cell metabolism: lymphocytes and lymphoma. FEBS Journal 2012, 279(15):2598-2609.
-
(2012)
FEBS Journal
, vol.279
, Issue.15
, pp. 2598-2609
-
-
Altman, B.J.1
Dang, C.V.2
-
22
-
-
77955483125
-
Activation of a metabolic gene regulatory network downstream of mTOR complex 1
-
Duvel K., et al. Activation of a metabolic gene regulatory network downstream of mTOR complex 1. Molecular Cell 2010, 39(2):171-183.
-
(2010)
Molecular Cell
, vol.39
, Issue.2
, pp. 171-183
-
-
Duvel, K.1
-
23
-
-
50049116472
-
SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth
-
Porstmann T., et al. SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth. Cell Metabolism 2008, 8(3):224-236.
-
(2008)
Cell Metabolism
, vol.8
, Issue.3
, pp. 224-236
-
-
Porstmann, T.1
-
24
-
-
84255199079
-
The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation
-
Wang R., et al. The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation. Immunity 2011, 35(6):871-882.
-
(2011)
Immunity
, vol.35
, Issue.6
, pp. 871-882
-
-
Wang, R.1
-
25
-
-
81055126129
-
Estrogen-related receptor-alpha is a metabolic regulator of effector T-cell activation and differentiation
-
Michalek R.D., et al. Estrogen-related receptor-alpha is a metabolic regulator of effector T-cell activation and differentiation. Proceedings of the National Academy of Sciences of the United States of America 2011, 108(45):18348-18353.
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, Issue.45
, pp. 18348-18353
-
-
Michalek, R.D.1
-
26
-
-
80052277906
-
Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1
-
Dang E.V., et al. Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1. Cell 2011, 146(5):772-784.
-
(2011)
Cell
, vol.146
, Issue.5
, pp. 772-784
-
-
Dang, E.V.1
-
27
-
-
79960369458
-
HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells
-
Shi L.Z., et al. HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells. Journal of Experimental Medicine 2011, 208(7):1367-1376.
-
(2011)
Journal of Experimental Medicine
, vol.208
, Issue.7
, pp. 1367-1376
-
-
Shi, L.Z.1
-
28
-
-
0036069699
-
The CD28 signaling pathway regulates glucose metabolism
-
Frauwirth K.A., et al. The CD28 signaling pathway regulates glucose metabolism. Immunity 2002, 16(6):769-777.
-
(2002)
Immunity
, vol.16
, Issue.6
, pp. 769-777
-
-
Frauwirth, K.A.1
-
29
-
-
33846005164
-
Phosphatidylinositol 3-kinase-dependent modulation of carnitine palmitoyltransferase 1A expression regulates lipid metabolism during hematopoietic cell growth
-
Deberardinis R.J., Lum J.J., Thompson C.B. Phosphatidylinositol 3-kinase-dependent modulation of carnitine palmitoyltransferase 1A expression regulates lipid metabolism during hematopoietic cell growth. Journal of Biological Chemistry 2006, 281(49):37372-37380.
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.49
, pp. 37372-37380
-
-
Deberardinis, R.J.1
Lum, J.J.2
Thompson, C.B.3
-
30
-
-
0017738601
-
A possible role for malonyl-CoA in the regulation of hepatic fatty acid oxidation and ketogenesis
-
McGarry J.D., Mannaerts G.P., Foster D.W. A possible role for malonyl-CoA in the regulation of hepatic fatty acid oxidation and ketogenesis. Journal of Clinical Investigation 1977, 60(1):265-270.
-
(1977)
Journal of Clinical Investigation
, vol.60
, Issue.1
, pp. 265-270
-
-
McGarry, J.D.1
Mannaerts, G.P.2
Foster, D.W.3
-
31
-
-
84855808743
-
Akt acutely activates the cholesterogenic transcription factor SREBP-2
-
Luu W., et al. Akt acutely activates the cholesterogenic transcription factor SREBP-2. Biochimica et Biophysica Acta 2012, 1823(2):458-464.
-
(2012)
Biochimica et Biophysica Acta
, vol.1823
, Issue.2
, pp. 458-464
-
-
Luu, W.1
-
32
-
-
17044422629
-
Glucose availability regulates IFN-gamma production and p70S6 kinase activation in CD8+ effector T cells
-
Cham C.M., Gajewski T.F. Glucose availability regulates IFN-gamma production and p70S6 kinase activation in CD8+ effector T cells. Journal of Immunology 2005, 174(8):4670-4677.
-
(2005)
Journal of Immunology
, vol.174
, Issue.8
, pp. 4670-4677
-
-
Cham, C.M.1
Gajewski, T.F.2
-
33
-
-
0038269105
-
Gene array and protein expression profiles suggest post-transcriptional regulation during CD8+ T cell differentiation
-
Cham C.M., et al. Gene array and protein expression profiles suggest post-transcriptional regulation during CD8+ T cell differentiation. Journal of Biological Chemistry 2003, 278(19):17044-17052.
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.19
, pp. 17044-17052
-
-
Cham, C.M.1
-
34
-
-
77952280516
-
Anergic T cells are metabolically anergic
-
Zheng Y., et al. Anergic T cells are metabolically anergic. Journal of Immunology 2009, 183(10):6095-6101.
-
(2009)
Journal of Immunology
, vol.183
, Issue.10
, pp. 6095-6101
-
-
Zheng, Y.1
-
35
-
-
0024502876
-
Glucose: glutamine and ketone body utilisation by resting and concanavalin A activated rat splenic lymphocytes
-
O'Rourke A.M., Rider C.C. Glucose: glutamine and ketone body utilisation by resting and concanavalin A activated rat splenic lymphocytes. Biochimica et Biophysica Acta 1989, 1010(3):342-345.
-
(1989)
Biochimica et Biophysica Acta
, vol.1010
, Issue.3
, pp. 342-345
-
-
O'Rourke, A.M.1
Rider, C.C.2
-
36
-
-
0015924743
-
Changes in the carbohydrate metabolism of mitogenically stimulated human peripheral lymphocytes. II. Relative importance of glycolysis and oxidative phosphorylation on phytohaemagglutinin stimulation
-
Roos D., Loos J.A. Changes in the carbohydrate metabolism of mitogenically stimulated human peripheral lymphocytes. II. Relative importance of glycolysis and oxidative phosphorylation on phytohaemagglutinin stimulation. Experimental Cell Research 1973, 77(1):127-135.
-
(1973)
Experimental Cell Research
, vol.77
, Issue.1
, pp. 127-135
-
-
Roos, D.1
Loos, J.A.2
-
38
-
-
20444373376
-
Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells
-
Battaglia M., Stabilini A., Roncarolo M.G. Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells. Blood 2005, 105(12):4743-4748.
-
(2005)
Blood
, vol.105
, Issue.12
, pp. 4743-4748
-
-
Battaglia, M.1
Stabilini, A.2
Roncarolo, M.G.3
-
39
-
-
66949173728
-
The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment
-
Delgoffe G.M., et al. The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment. Immunity 2009, 30(6):832-844.
-
(2009)
Immunity
, vol.30
, Issue.6
, pp. 832-844
-
-
Delgoffe, G.M.1
-
41
-
-
34547098277
-
Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression
-
Borsellino G., et al. Expression of ectonucleotidase CD39 by Foxp3+ Treg cells: hydrolysis of extracellular ATP and immune suppression. Blood 2007, 110(4):1225-1232.
-
(2007)
Blood
, vol.110
, Issue.4
, pp. 1225-1232
-
-
Borsellino, G.1
-
42
-
-
78650651362
-
Regulatory T cells interfere with glutathione metabolism in dendritic cells and T cells
-
Yan Z., Garg S.K., Banerjee R., Regulatory T cells interfere with glutathione metabolism in dendritic cells and T cells. Journal of Biological Chemistry 2010, 285(53):41525-41532.
-
(2010)
Journal of Biological Chemistry
, vol.285
, Issue.53
, pp. 41525-41532
-
-
Yan, Z.1
Garg, S.K.2
Banerjee, R.3
-
43
-
-
67650074206
-
MTOR regulates memory CD8 T-cell differentiation
-
Araki K., et al. mTOR regulates memory CD8 T-cell differentiation. Nature 2009, 460(7251):108-112.
-
(2009)
Nature
, vol.460
, Issue.7251
, pp. 108-112
-
-
Araki, K.1
-
44
-
-
67650096912
-
Enhancing CD8 T-cell memory by modulating fatty acid metabolism
-
Pearce E.L., et al. Enhancing CD8 T-cell memory by modulating fatty acid metabolism. Nature 2009, 460(7251):103-107.
-
(2009)
Nature
, vol.460
, Issue.7251
, pp. 103-107
-
-
Pearce, E.L.1
-
45
-
-
84856183120
-
Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development
-
van der Windt G.J., et al. Mitochondrial respiratory capacity is a critical regulator of CD8+ T cell memory development. Immunity 2012, 36(1):68-78.
-
(2012)
Immunity
, vol.36
, Issue.1
, pp. 68-78
-
-
van der Windt, G.J.1
-
47
-
-
73949112134
-
Differentiation stage-specific requirement in hypoxia-inducible factor-1alpha-regulated glycolytic pathway during murine B cell development in bone marrow
-
Kojima H., et al. Differentiation stage-specific requirement in hypoxia-inducible factor-1alpha-regulated glycolytic pathway during murine B cell development in bone marrow. Journal of Immunology 2010, 184(1):154-163.
-
(2010)
Journal of Immunology
, vol.184
, Issue.1
, pp. 154-163
-
-
Kojima, H.1
-
48
-
-
80052458664
-
Metabolomics of B to plasma cell differentiation
-
Garcia-Manteiga J.M., et al. Metabolomics of B to plasma cell differentiation. Journal of Proteome Research 2011, 10(9):4165-4176.
-
(2011)
Journal of Proteome Research
, vol.10
, Issue.9
, pp. 4165-4176
-
-
Garcia-Manteiga, J.M.1
-
49
-
-
0021845948
-
The essential role of l-glutamine in lymphocyte differentiation in vitro
-
Crawford J., Cohen H.J. The essential role of l-glutamine in lymphocyte differentiation in vitro. Journal of Cellular Physiology 1985, 124(2):275-282.
-
(1985)
Journal of Cellular Physiology
, vol.124
, Issue.2
, pp. 275-282
-
-
Crawford, J.1
Cohen, H.J.2
-
50
-
-
0037332128
-
Sequential waves of functionally related proteins are expressed when B cells prepare for antibody secretion
-
van Anken E., et al. Sequential waves of functionally related proteins are expressed when B cells prepare for antibody secretion. Immunity 2003, 18(2):243-253.
-
(2003)
Immunity
, vol.18
, Issue.2
, pp. 243-253
-
-
van Anken, E.1
-
51
-
-
3142658576
-
XBP1: downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation
-
Shaffer A.L., et al. XBP1: downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation. Immunity 2004, 21(1):81-93.
-
(2004)
Immunity
, vol.21
, Issue.1
, pp. 81-93
-
-
Shaffer, A.L.1
-
52
-
-
84866355862
-
IL-6 Triggers IL-21 production by human CD4(+) T cells to drive STAT3-dependent plasma cell differentiation in B cells
-
Diehl S.A., et al. IL-6 Triggers IL-21 production by human CD4(+) T cells to drive STAT3-dependent plasma cell differentiation in B cells. Immunology and Cell Biology 2012, 90(8):802-811.
-
(2012)
Immunology and Cell Biology
, vol.90
, Issue.8
, pp. 802-811
-
-
Diehl, S.A.1
-
53
-
-
59849101586
-
Function of mitochondrial Stat3 in cellular respiration
-
Wegrzyn J., et al. Function of mitochondrial Stat3 in cellular respiration. Science 2009, 323(5915):793-797.
-
(2009)
Science
, vol.323
, Issue.5915
, pp. 793-797
-
-
Wegrzyn, J.1
-
54
-
-
77957054466
-
The mammalian target of rapamycin: linking T cell differentiation, function, and metabolism
-
Powell J.D., Delgoffe G.M. The mammalian target of rapamycin: linking T cell differentiation, function, and metabolism. Immunity 2010, 33(3):301-311.
-
(2010)
Immunity
, vol.33
, Issue.3
, pp. 301-311
-
-
Powell, J.D.1
Delgoffe, G.M.2
-
55
-
-
20844449238
-
AMP-activated protein kinase induces a p53-dependent metabolic checkpoint
-
Jones R.G., et al. AMP-activated protein kinase induces a p53-dependent metabolic checkpoint. Molecular Cell 2005, 18(3):283-293.
-
(2005)
Molecular Cell
, vol.18
, Issue.3
, pp. 283-293
-
-
Jones, R.G.1
-
56
-
-
68949096538
-
Mitochondrial dysfunction contributes to oncogene-induced senescence
-
Moiseeva O., et al. Mitochondrial dysfunction contributes to oncogene-induced senescence. Molecular and Cellular Biology 2009, 29(16):4495-4507.
-
(2009)
Molecular and Cellular Biology
, vol.29
, Issue.16
, pp. 4495-4507
-
-
Moiseeva, O.1
-
57
-
-
84865300719
-
Metabolism and autophagy in the immune system: immunometabolism comes of age
-
Rathmell J.C. Metabolism and autophagy in the immune system: immunometabolism comes of age. Immunological Reviews 2012, 249(1):5-13.
-
(2012)
Immunological Reviews
, vol.249
, Issue.1
, pp. 5-13
-
-
Rathmell, J.C.1
-
58
-
-
77956095537
-
Mitochondria and cell death: outer membrane permeabilization and beyond
-
Tait S.W., Green D.R. Mitochondria and cell death: outer membrane permeabilization and beyond. Nature Reviews Molecular Cell Biology 2010, 11(9):621-632.
-
(2010)
Nature Reviews Molecular Cell Biology
, vol.11
, Issue.9
, pp. 621-632
-
-
Tait, S.W.1
Green, D.R.2
-
59
-
-
34249279169
-
GAPDH and autophagy preserve survival after apoptotic cytochrome c release in the absence of caspase activation
-
Colell A., et al. GAPDH and autophagy preserve survival after apoptotic cytochrome c release in the absence of caspase activation. Cell 2007, 129(5):983-997.
-
(2007)
Cell
, vol.129
, Issue.5
, pp. 983-997
-
-
Colell, A.1
-
60
-
-
68149107692
-
BAD: undertaker by night, candyman by day
-
Danial N.N. BAD: undertaker by night, candyman by day. Oncogene 2008, 27(Suppl. 1):S53-S70.
-
(2008)
Oncogene
, vol.27
, Issue.SUPPL. 1
-
-
Danial, N.N.1
-
61
-
-
0041357164
-
BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis
-
Danial N.N., et al. BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis. Nature 2003, 424(6951):952-956.
-
(2003)
Nature
, vol.424
, Issue.6951
, pp. 952-956
-
-
Danial, N.N.1
-
62
-
-
78649973189
-
The proapoptotic function of Noxa in human leukemia cells is regulated by the kinase Cdk5 and by glucose
-
Lowman X.H., et al. The proapoptotic function of Noxa in human leukemia cells is regulated by the kinase Cdk5 and by glucose. Molecular Cell 2010, 40(5):823-833.
-
(2010)
Molecular Cell
, vol.40
, Issue.5
, pp. 823-833
-
-
Lowman, X.H.1
-
63
-
-
0036510541
-
Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis
-
Pastorino J.G., Shulga N., Hoek J.B. Mitochondrial binding of hexokinase II inhibits Bax-induced cytochrome c release and apoptosis. Journal of Biological Chemistry 2002, 277(9):7610-7618.
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.9
, pp. 7610-7618
-
-
Pastorino, J.G.1
Shulga, N.2
Hoek, J.B.3
-
64
-
-
0043204996
-
VDAC2 inhibits BAK activation and mitochondrial apoptosis
-
Cheng E.H., et al. VDAC2 inhibits BAK activation and mitochondrial apoptosis. Science 2003, 301(5632):513-517.
-
(2003)
Science
, vol.301
, Issue.5632
, pp. 513-517
-
-
Cheng, E.H.1
-
65
-
-
84869081493
-
Disruption of the VDAC2-Bak interaction by Bcl-x(S) mediates efficient induction of apoptosis in melanoma cells
-
Plotz M., et al. Disruption of the VDAC2-Bak interaction by Bcl-x(S) mediates efficient induction of apoptosis in melanoma cells. Cell Death and Differentiation 2012, 19(12):1928-1938.
-
(2012)
Cell Death and Differentiation
, vol.19
, Issue.12
, pp. 1928-1938
-
-
Plotz, M.1
-
66
-
-
33745006592
-
The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells
-
Alves N.L., et al. The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells. Immunity 2006, 24(6):703-716.
-
(2006)
Immunity
, vol.24
, Issue.6
, pp. 703-716
-
-
Alves, N.L.1
-
67
-
-
77949653043
-
Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation
-
Pradelli L.A., et al. Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation. Oncogene 2010, 29(11):1641-1652.
-
(2010)
Oncogene
, vol.29
, Issue.11
, pp. 1641-1652
-
-
Pradelli, L.A.1
-
68
-
-
77954175674
-
Mcl-1: the molecular regulation of protein function
-
Thomas L.W., Lam C., Edwards S.W. Mcl-1: the molecular regulation of protein function. FEBS Letters 2010, 584(14):2981-2989.
-
(2010)
FEBS Letters
, vol.584
, Issue.14
, pp. 2981-2989
-
-
Thomas, L.W.1
Lam, C.2
Edwards, S.W.3
-
69
-
-
64849113485
-
Control of mitochondrial apoptosis by the Bcl-2 family
-
Brunelle J.K., Letai A. Control of mitochondrial apoptosis by the Bcl-2 family. Journal of Cell Science 2009, 122(Pt 4):437-441.
-
(2009)
Journal of Cell Science
, vol.122
, Issue.PART 4
, pp. 437-441
-
-
Brunelle, J.K.1
Letai, A.2
-
70
-
-
61449206074
-
Glucose metabolism attenuates p53 and Puma-dependent cell death upon growth factor deprivation
-
Zhao Y., et al. Glucose metabolism attenuates p53 and Puma-dependent cell death upon growth factor deprivation. Journal of Biological Chemistry 2008, 283(52):36344-36353.
-
(2008)
Journal of Biological Chemistry
, vol.283
, Issue.52
, pp. 36344-36353
-
-
Zhao, Y.1
-
71
-
-
34250758642
-
ER stress triggers apoptosis by activating BH3-only protein Bim
-
Puthalakath H., et al. ER stress triggers apoptosis by activating BH3-only protein Bim. Cell 2007, 129(7):1337-1349.
-
(2007)
Cell
, vol.129
, Issue.7
, pp. 1337-1349
-
-
Puthalakath, H.1
-
72
-
-
78649704325
-
Autophagy and metabolism
-
Rabinowitz J.D., White E. Autophagy and metabolism. Science 2010, 330(6009):1344-1348.
-
(2010)
Science
, vol.330
, Issue.6009
, pp. 1344-1348
-
-
Rabinowitz, J.D.1
White, E.2
-
73
-
-
79955469013
-
Autophagy is essential to suppress cell stress and to allow BCR-Abl-mediated leukemogenesis
-
Altman B.J., et al. Autophagy is essential to suppress cell stress and to allow BCR-Abl-mediated leukemogenesis. Oncogene 2011, 30(16):1855-1867.
-
(2011)
Oncogene
, vol.30
, Issue.16
, pp. 1855-1867
-
-
Altman, B.J.1
-
75
-
-
77954656984
-
Glucose deprivation induces an atypical form of apoptosis mediated by caspase-8 in Bax-, Bak-deficient cells
-
Caro-Maldonado A., et al. Glucose deprivation induces an atypical form of apoptosis mediated by caspase-8 in Bax-, Bak-deficient cells. Cell Death and Differentiation 2010, 17(8):1335-1344.
-
(2010)
Cell Death and Differentiation
, vol.17
, Issue.8
, pp. 1335-1344
-
-
Caro-Maldonado, A.1
-
76
-
-
79954593191
-
Conventional and novel approaches to immunosuppression
-
Floreth T., Bhorade S.M., Ahya V.N. Conventional and novel approaches to immunosuppression. Clinics in Chest Medicine 2011, 32(2):265-277.
-
(2011)
Clinics in Chest Medicine
, vol.32
, Issue.2
, pp. 265-277
-
-
Floreth, T.1
Bhorade, S.M.2
Ahya, V.N.3
-
77
-
-
75649122284
-
Dichloroacetate alleviates development of collagen II-induced arthritis in female DBA/1 mice
-
Bian L., et al. Dichloroacetate alleviates development of collagen II-induced arthritis in female DBA/1 mice. Arthritis Research and Therapy 2009, 11(5):R132.
-
(2009)
Arthritis Research and Therapy
, vol.11
, Issue.5
-
-
Bian, L.1
-
78
-
-
79251500689
-
Manipulating the bioenergetics of alloreactive T cells causes their selective apoptosis and arrests graft-versus-host disease
-
Gatza E., et al. Manipulating the bioenergetics of alloreactive T cells causes their selective apoptosis and arrests graft-versus-host disease. Science Translational Medicine 2011, 3(67):67ra8.
-
(2011)
Science Translational Medicine
, vol.3
, Issue.67
-
-
Gatza, E.1
-
79
-
-
0026080617
-
Increased oxidative metabolism in phytohemagglutinin-stimulated lymphocytes from patients with systemic lupus erythematosus is associated with serum SSA antibody
-
Benke P.J., Drisko J., Ahmad P. Increased oxidative metabolism in phytohemagglutinin-stimulated lymphocytes from patients with systemic lupus erythematosus is associated with serum SSA antibody. Biochemical Medicine and Metabolic Biology 1991, 45(1):28-40.
-
(1991)
Biochemical Medicine and Metabolic Biology
, vol.45
, Issue.1
, pp. 28-40
-
-
Benke, P.J.1
Drisko, J.2
Ahmad, P.3
-
80
-
-
0037100275
-
Persistent mitochondrial hyperpolarization: increased reactive oxygen intermediate production, and cytoplasmic alkalinization characterize altered IL-10 signaling in patients with systemic lupus erythematosus
-
Gergely P., et al. Persistent mitochondrial hyperpolarization: increased reactive oxygen intermediate production, and cytoplasmic alkalinization characterize altered IL-10 signaling in patients with systemic lupus erythematosus. Journal of Immunology 2002, 169(2):1092-1101.
-
(2002)
Journal of Immunology
, vol.169
, Issue.2
, pp. 1092-1101
-
-
Gergely, P.1
-
81
-
-
0036161789
-
Mitochondrial hyperpolarization and ATP depletion in patients with systemic lupus erythematosus
-
Gergely P., et al. Mitochondrial hyperpolarization and ATP depletion in patients with systemic lupus erythematosus. Arthritis and Rheumatism 2002, 46(1):175-190.
-
(2002)
Arthritis and Rheumatism
, vol.46
, Issue.1
, pp. 175-190
-
-
Gergely, P.1
-
82
-
-
0037333995
-
Attenuation of autoimmune disease in Fas-deficient mice by treatment with a cytotoxic benzodiazepine
-
Bednarski J.J., et al. Attenuation of autoimmune disease in Fas-deficient mice by treatment with a cytotoxic benzodiazepine. Arthritis and Rheumatism 2003, 48(3):757-766.
-
(2003)
Arthritis and Rheumatism
, vol.48
, Issue.3
, pp. 757-766
-
-
Bednarski, J.J.1
-
83
-
-
78751648703
-
Sugar-free approaches to cancer cell killing
-
El Mjiyad N., et al. Sugar-free approaches to cancer cell killing. Oncogene 2011, 30(3):253-264.
-
(2011)
Oncogene
, vol.30
, Issue.3
, pp. 253-264
-
-
El Mjiyad, N.1
-
84
-
-
84863006442
-
Novel molecular mechanisms of antitumor action of dichloroacetate against T cell lymphoma: implication of altered glucose metabolism, pH homeostasis and cell survival regulation
-
Kumar A., Kant S., Singh S.M. Novel molecular mechanisms of antitumor action of dichloroacetate against T cell lymphoma: implication of altered glucose metabolism, pH homeostasis and cell survival regulation. Chemico-Biological Interactions 2012, 199(1):29-37.
-
(2012)
Chemico-Biological Interactions
, vol.199
, Issue.1
, pp. 29-37
-
-
Kumar, A.1
Kant, S.2
Singh, S.M.3
-
85
-
-
17844366842
-
Identification and validation of the mitochondrial F1F0-ATPase as the molecular target of the immunomodulatory benzodiazepine Bz-423
-
Johnson K.M., et al. Identification and validation of the mitochondrial F1F0-ATPase as the molecular target of the immunomodulatory benzodiazepine Bz-423. Chemistry and Biology 2005, 12(4):485-496.
-
(2005)
Chemistry and Biology
, vol.12
, Issue.4
, pp. 485-496
-
-
Johnson, K.M.1
-
86
-
-
4344640378
-
Effect of pioglitazone treatment in a patient with secondary multiple sclerosis
-
Pershadsingh H.A., et al. Effect of pioglitazone treatment in a patient with secondary multiple sclerosis. Journal of Neuroinflammation 2004, 1(1):3.
-
(2004)
Journal of Neuroinflammation
, vol.1
, Issue.1
, pp. 3
-
-
Pershadsingh, H.A.1
-
88
-
-
0036083066
-
Leflunomide for the treatment of rheumatoid arthritis and autoimmunity
-
Sanders S., Harisdangkul V. Leflunomide for the treatment of rheumatoid arthritis and autoimmunity. American Journal of the Medical Sciences 2002, 323(4):190-193.
-
(2002)
American Journal of the Medical Sciences
, vol.323
, Issue.4
, pp. 190-193
-
-
Sanders, S.1
Harisdangkul, V.2
|