메뉴 건너뛰기




Volumn 19, Issue 23, 1999, Pages 10417-10427

Brain uncoupling protein 2: Uncoupled neuronal mitochondria predict thermal synapses in homeostatic centers

Author keywords

Autonomic and endocrine regulation; Axon terminals; Brain; Cranial temperature; Neurons; Proton leak; Uncoupling proteins

Indexed keywords

CORTICOTROPIN RELEASING FACTOR RECEPTOR; GONADORELIN; MELANIN CONCENTRATING HORMONE; NEUROPEPTIDE Y; OREXIN; OXYTOCIN; UNCOUPLING PROTEIN 2; VASOPRESSIN;

EID: 0033492873     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.19-23-10417.1999     Document Type: Article
Times cited : (166)

References (49)
  • 1
    • 0029554127 scopus 로고
    • Brain temperature and hippocampal function
    • Andersen P, Moser EI (1995) Brain temperature and hippocampal function. Hippocampus 5:491-498.
    • (1995) Hippocampus , vol.5 , pp. 491-498
    • Andersen, P.1    Moser, E.I.2
  • 4
    • 0342334561 scopus 로고
    • Molecular approach to thermogenesis in brown adipose tissue: CDNA cloning of the mitochondrial uncoupling protein
    • Bouillaud F, Ricquier D, Thibault J, Weissenbach J (1985) Molecular approach to thermogenesis in brown adipose tissue: cDNA cloning of the mitochondrial uncoupling protein. Proc Natl Acad Sci USA 82:445-448.
    • (1985) Proc Natl Acad Sci USA , vol.82 , pp. 445-448
    • Bouillaud, F.1    Ricquier, D.2    Thibault, J.3    Weissenbach, J.4
  • 5
    • 0032211444 scopus 로고    scopus 로고
    • Synaptic inhibition: Its role in suprachiasmatic nucleus neuronal thermosensitivity and temperature compensation in the rat
    • Lond
    • Burgoon PW, Boulant JA (1998) Synaptic inhibition: its role in suprachiasmatic nucleus neuronal thermosensitivity and temperature compensation in the rat. J Physiol (Lond) 512:793-807.
    • (1998) J Physiol , vol.512 , pp. 793-807
    • Burgoon, P.W.1    Boulant, J.A.2
  • 6
    • 0029048408 scopus 로고
    • Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
    • Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P (1995) Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science 269:546-549.
    • (1995) Science , vol.269 , pp. 546-549
    • Campfield, L.A.1    Smith, F.J.2    Guisez, Y.3    Devos, R.4    Burn, P.5
  • 7
    • 0030932565 scopus 로고    scopus 로고
    • Noninvasive measurements of human brain temperature using volume-localised proton magnetic resonance spectroscopy
    • Corbett R, Laptook A, Weatherall P (1997) Noninvasive measurements of human brain temperature using volume-localised proton magnetic resonance spectroscopy. J. Cereb Blood Flow Metab 17:363-367.
    • (1997) J. Cereb Blood Flow Metab , vol.17 , pp. 363-367
    • Corbett, R.1    Laptook, A.2    Weatherall, P.3
  • 9
    • 0033082380 scopus 로고    scopus 로고
    • From lesions to leptin: Hypothalamic control of food intake and body weight
    • Elmquist JK, Elias CF, Saper CB (1999) From lesions to leptin: hypothalamic control of food intake and body weight. Neuron 2:221-232.
    • (1999) Neuron , vol.2 , pp. 221-232
    • Elmquist, J.K.1    Elias, C.F.2    Saper, C.B.3
  • 10
    • 0030050511 scopus 로고    scopus 로고
    • Contribution of single-unit spike waveform changes to temperature-induced alterations in hippocampal population spikes
    • Erickson CA, Jung MW, McNaughton BL, Barnes CA (1996) Contribution of single-unit spike waveform changes to temperature-induced alterations in hippocampal population spikes. Exp Brain Res 107:348-360.
    • (1996) Exp Brain Res , vol.107 , pp. 348-360
    • Erickson, C.A.1    Jung, M.W.2    McNaughton, B.L.3    Barnes, C.A.4
  • 12
    • 0032558725 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight in mammals
    • Friedman JF, Halaas JL (1998) Leptin and the regulation of body weight in mammals. Nature 395:763-771.
    • (1998) Nature , vol.395 , pp. 763-771
    • Friedman, J.F.1    Halaas, J.L.2
  • 13
    • 0030869755 scopus 로고    scopus 로고
    • Uncoupling protein-3 is a mediator of thermogenesis regulated by thyroid hormone, beta3-adrenergic agonists, and leptin
    • Gong DW, He Y, Karas M, Reitman M (1997) Uncoupling protein-3 is a mediator of thermogenesis regulated by thyroid hormone, beta3-adrenergic agonists, and leptin. J Biol Chem 272:24129-24132.
    • (1997) J Biol Chem , vol.272 , pp. 24129-24132
    • Gong, D.W.1    He, Y.2    Karas, M.3    Reitman, M.4
  • 14
    • 0032577279 scopus 로고    scopus 로고
    • Uncoupling proteins provide new clue to obesity's causes
    • GuraT (1998) Uncoupling proteins provide new clue to obesity's causes. Science 280:1369-1370.
    • (1998) Science , vol.280 , pp. 1369-1370
    • Gura, T.1
  • 15
    • 0032130554 scopus 로고    scopus 로고
    • Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons
    • Hahn TM, Breininger JF, Baskin DG, Schwartz MW (1998) Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons. Nat Neurosci 1:271-272.
    • (1998) Nat Neurosci , vol.1 , pp. 271-272
    • Hahn, T.M.1    Breininger, J.F.2    Baskin, D.G.3    Schwartz, M.W.4
  • 17
    • 0031039954 scopus 로고    scopus 로고
    • Suprachiasmatic efferents avoid phenestrated capillaries but innervate ncuroendocrine cells including those producing dopamine
    • Horvath TL (1997) Suprachiasmatic efferents avoid phenestrated capillaries but innervate ncuroendocrine cells including those producing dopamine. Endocrinology 138:1312-1320.
    • (1997) Endocrinology , vol.138 , pp. 1312-1320
    • Horvath, T.L.1
  • 18
    • 0032520133 scopus 로고    scopus 로고
    • An alternate pathway for visual signal integration into the hypothalamo-pituitary axis: Retinorecipient intergeniculate neurons project to various regions of the hypothalamus and innervate neuroendocrine cells including those producing dopamine
    • Horvath TL (1998) An alternate pathway for visual signal integration into the hypothalamo-pituitary axis: retinorecipient intergeniculate neurons project to various regions of the hypothalamus and innervate neuroendocrine cells including those producing dopamine. J Neurosci 18:1546-1558.
    • (1998) J Neurosci , vol.18 , pp. 1546-1558
    • Horvath, T.L.1
  • 19
    • 0030990363 scopus 로고    scopus 로고
    • Heterogeneity in the neuropeptide Y-containing neurons of the rat arcuate nucleus: GABAergic and non-GABAergic subpopulations
    • Horvath TL, Bechmann I, Kalra SP, Naftolin F, Leranth C (1997) Heterogeneity in the neuropeptide Y-containing neurons of the rat arcuate nucleus: GABAergic and non-GABAergic subpopulations. Brain Res 756:283-286.
    • (1997) Brain Res , vol.756 , pp. 283-286
    • Horvath, T.L.1    Bechmann, I.2    Kalra, S.P.3    Naftolin, F.4    Leranth, C.5
  • 20
    • 0033081871 scopus 로고    scopus 로고
    • Synaptic interaction between hypocretin (orexin) and neuropeptide Y cells in the rodent and primate hypothalamus: A novel circuit implicated in metabolic and endocrine regulations
    • Horvath TL, Diano S, van den Pol AN (1999) Synaptic interaction between hypocretin (orexin) and neuropeptide Y cells in the rodent and primate hypothalamus: a novel circuit implicated in metabolic and endocrine regulations. J Neurosci 1:1072-1087.
    • (1999) J Neurosci , vol.1 , pp. 1072-1087
    • Horvath, T.L.1    Diano, S.2    Van Den Pol, A.N.3
  • 21
    • 0030850411 scopus 로고    scopus 로고
    • Appetite and body weight regulation: Is it all in the brain?
    • Kalra SP (1997) Appetite and body weight regulation: is it all in the brain? Neuron 19:227-230.
    • (1997) Neuron , vol.19 , pp. 227-230
    • Kalra, S.P.1
  • 22
    • 0032417903 scopus 로고    scopus 로고
    • Neuroendocrine interactions between galanin, opioids, and neuropeptide Y in the control of reproduction and appetite
    • Kalra SP, Horvath TL (1998) Neuroendocrine interactions between galanin, opioids, and neuropeptide Y in the control of reproduction and appetite. Annals of the NY Acad Sci 863:236-240.
    • (1998) Annals of the NY Acad Sci , vol.863 , pp. 236-240
    • Kalra, S.P.1    Horvath, T.L.2
  • 23
    • 0033038418 scopus 로고    scopus 로고
    • Interacting appetite regulating pathways in the hypothalamic regulation of body weight
    • Kalra SP, Xu B, Dube MG, Pu S, Horvath TL, Kalra PS (1999) Interacting appetite regulating pathways in the hypothalamic regulation of body weight. Endocr Rev 20:67-100.
    • (1999) Endocr Rev , vol.20 , pp. 67-100
    • Kalra, S.P.1    Xu, B.2    Dube, M.G.3    Pu, S.4    Horvath, T.L.5    Kalra, P.S.6
  • 24
    • 0025861442 scopus 로고
    • The uncoupling protein UCP: A membraneous mitochondrial ion carrier exclusively expressed in brown adipose tissue
    • Klaus S, Casteilla L, Bouillaud F, Ricquier D (1991) The uncoupling protein UCP: a membraneous mitochondrial ion carrier exclusively expressed in brown adipose tissue. Int J Biochem 9:791-801.
    • (1991) Int J Biochem , vol.9 , pp. 791-801
    • Klaus, S.1    Casteilla, L.2    Bouillaud, F.3    Ricquier, D.4
  • 25
    • 0032544720 scopus 로고    scopus 로고
    • Fatty acids as natural uncouplers preventing generation of O2.- and H2O2 by mitochondria in the resting state
    • Korshunov SS, Korkina OV, Ruuge EK, Skulachev VP, Starkov AA (1998) Fatty acids as natural uncouplers preventing generation of O2.- and H2O2 by mitochondria in the resting state. FEBS Lett 435:215-218.
    • (1998) FEBS Lett , vol.435 , pp. 215-218
    • Korshunov, S.S.1    Korkina, O.V.2    Ruuge, E.K.3    Skulachev, V.P.4    Starkov, A.A.5
  • 29
    • 0032519709 scopus 로고    scopus 로고
    • Effect of 3,5-di-iodo-L-thyronine on the mitochondrial energy-transduction apparatus
    • Lombardi A, Lanni A, Moreno M, Brand MD, Goglia F (1998) Effect of 3,5-di-iodo-L-thyronine on the mitochondrial energy-transduction apparatus. Biochem J 330:521-526.
    • (1998) Biochem J , vol.330 , pp. 521-526
    • Lombardi, A.1    Lanni, A.2    Moreno, M.3    Brand, M.D.4    Goglia, F.5
  • 30
    • 0032998265 scopus 로고    scopus 로고
    • UCP4, a novel brain-specific mitochondrial protein that reduces membrane potential in mammalian cells
    • Mao W, Yu XX, Zhong A, Li W, Brush J, Sherwood SW, Adams SH, Pan G (1999) UCP4, a novel brain-specific mitochondrial protein that reduces membrane potential in mammalian cells. FEBS Lett 443:326-330.
    • (1999) FEBS Lett , vol.443 , pp. 326-330
    • Mao, W.1    Yu, X.X.2    Zhong, A.3    Li, W.4    Brush, J.5    Sherwood, S.W.6    Adams, S.H.7    Pan, G.8
  • 31
    • 0025264291 scopus 로고
    • Epidural temperature and possible intracerebral temperature gradients in man
    • Mellergard P, Nordstrom C-H (1990) Epidural temperature and possible intracerebral temperature gradients in man. Br J Neurosurg 4:31-38.
    • (1990) Br J Neurosurg , vol.4 , pp. 31-38
    • Mellergard, P.1    Nordstrom, C.-H.2
  • 32
    • 0029982124 scopus 로고    scopus 로고
    • Relationship between neuronal activity and brain temperature in rats
    • Moser EI, Mathiesen I (1996) Relationship between neuronal activity and brain temperature in rats. NeuroReport 7:1876-1880.
    • (1996) NeuroReport , vol.7 , pp. 1876-1880
    • Moser, E.I.1    Mathiesen, I.2
  • 34
    • 0021322138 scopus 로고
    • Thermogenic mechanism in brown fat
    • Nicholls DG, Locke RM (1984) Thermogenic mechanism in brown fat. Physiol Rev 64:1-64.
    • (1984) Physiol Rev , vol.64 , pp. 1-64
    • Nicholls, D.G.1    Locke, R.M.2
  • 35
    • 0030764741 scopus 로고    scopus 로고
    • Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein
    • Ollmann MM, Wilson BD, Yang YK, Kerns JA, Chen Y, Gantz I, Barsh GS (1997) Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein. Science 278:135-138.
    • (1997) Science , vol.278 , pp. 135-138
    • Ollmann, M.M.1    Wilson, B.D.2    Yang, Y.K.3    Kerns, J.A.4    Chen, Y.5    Gantz, I.6    Barsh, G.S.7
  • 36
    • 0021001219 scopus 로고
    • Glucose as a regulator of neuronal activity
    • Oomura Y (1983) Glucose as a regulator of neuronal activity. Adv Metab Disord 10:31-65.
    • (1983) Adv Metab Disord , vol.10 , pp. 31-65
    • Oomura, Y.1
  • 39
    • 0032549811 scopus 로고    scopus 로고
    • A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
    • Puigserver P, Wu Z, Park CW, Graves R, Wright M, Spiegelman M (1998) A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 92:829-839.
    • (1998) Cell , vol.92 , pp. 829-839
    • Puigserver, P.1    Wu, Z.2    Park, C.W.3    Graves, R.4    Wright, M.5    Spiegelman, M.6
  • 42
    • 0028556635 scopus 로고
    • Characteristics of mitochondrial proton leak and control of oxidative phosphorylation in the major oxygen-consuming tissues of the rat
    • Rolfe DF, Hulbert AJ, Brand MD (1994) Characteristics of mitochondrial proton leak and control of oxidative phosphorylation in the major oxygen-consuming tissues of the rat. Biochim Biophys Acta 1188:405-416.
    • (1994) Biochim Biophys Acta , vol.1188 , pp. 405-416
    • Rolfe, D.F.1    Hulbert, A.J.2    Brand, M.D.3
  • 44
    • 0031832185 scopus 로고    scopus 로고
    • Role of UCP homologues in skeletal muscles and brown adipose tissue: Mediators of thermogenesis or regulators of lipids as fuel substrate?
    • Samec S, Seydoux J, Dulloo AG (1998) Role of UCP homologues in skeletal muscles and brown adipose tissue: mediators of thermogenesis or regulators of lipids as fuel substrate? FASEB J 12:715-724.
    • (1998) FASEB J , vol.12 , pp. 715-724
    • Samec, S.1    Seydoux, J.2    Dulloo, A.G.3
  • 46
    • 0030983772 scopus 로고    scopus 로고
    • Brain temperature monitoring and modulation in patients with severe MCA infarction
    • Schwab S, Spranger M, Aschoff A, Steiner T, Hacke W (1997) Brain temperature monitoring and modulation in patients with severe MCA infarction. Neurology 48:762-767.
    • (1997) Neurology , vol.48 , pp. 762-767
    • Schwab, S.1    Spranger, M.2    Aschoff, A.3    Steiner, T.4    Hacke, W.5
  • 47
    • 0031788924 scopus 로고    scopus 로고
    • Overexpression of muscle uncoupling protein-2 content in human obesity associates with reduced skeletal muscle lipid utilization
    • Simoneau JA, Kelly DE, Neverova M, Warden CH (1998) Overexpression of muscle uncoupling protein-2 content in human obesity associates with reduced skeletal muscle lipid utilization. FASEB J 12:1739-1745.
    • (1998) FASEB J , vol.12 , pp. 1739-1745
    • Simoneau, J.A.1    Kelly, D.E.2    Neverova, M.3    Warden, C.H.4
  • 48
    • 0032566750 scopus 로고    scopus 로고
    • Thermoregulatory uncoupling in heart muscle mitochondria: Involvement of the ATP/ADP antiporter and uncoupling protein
    • Simonyan RA, Skulachev VP (1998) Thermoregulatory uncoupling in heart muscle mitochondria: involvement of the ATP/ADP antiporter and uncoupling protein. FEBS Lett 436:81-84.
    • (1998) FEBS Lett , vol.436 , pp. 81-84
    • Simonyan, R.A.1    Skulachev, V.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.