Type I interferon drives tumor necrosis factor-induced lethal shock

Journal of Experimental Medicine

Volumn 206, Issue 9, 2009, Pages 1873-1882

  Huys, Liesbeth ^a,b   Van Hauwermeiren, Filip ^a,b   Dejager, Lien ^a,b   Dejonckheere, Eline ^a,b   Lienenklaus, Stefan ^c   Weiss, Siegfried ^c   Leclercq, Georges ^d   Libert, Claude ^a,b  

^a DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^b GHENT UNIVERSITY   (Belgium)

^c HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^d GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON RECEPTOR; ALPHA INTERFERON RECEPTOR 1; BETA INTERFERON; CHEMOKINE; CXCL11 CHEMOKINE; CXCL9 CHEMOKINE; CYTOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERFERON; INTERFERON REGULATORY FACTOR 7; INTERLEUKIN 6; PROTEIN; PROTEIN IFIT2; RECOMBINANT GAMMA INTERFERON; RECOMBINANT TUMOR NECROSIS FACTOR; STAT1 PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL DEATH; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA RESPONSIVE ELEMENT; DRUG SAFETY; GENE EXPRESSION; HYPOTHERMIA; IMMUNOHISTOCHEMISTRY; INFLAMMATORY DISEASE; INTESTINE CELL; KNOCKOUT MOUSE; LEUKOCYTE; LIVER CELL; MEDIATOR; MORTALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTECTION; SHOCK; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; WILD TYPE;

ANIMALS; GENE EXPRESSION PROFILING; HYPOTHERMIA; IMMUNOHISTOCHEMISTRY; IN SITU NICK-END LABELING; INTERFERON TYPE I; INTERLEUKIN-6; LIVER; MICE; MICE, KNOCKOUT; RECEPTOR, INTERFERON ALPHA-BETA; SIGNAL TRANSDUCTION; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; TUMOR NECROSIS FACTOR-ALPHA;

EID: 69549124084     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20090213     Document Type: Article

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