-
3
-
-
84866544929
-
Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium
-
Robinson, N., S. McComb, R. Mulligan, R. Dudani, L. Krishnan, and S. Sad. 2012. Type I interferon induces necroptosis in macrophages during infection with Salmonella enterica serovar Typhimurium. Nat. Immunol. 13:954-962.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 954-962
-
-
Robinson, N.1
McComb, S.2
Mulligan, R.3
Dudani, R.4
Krishnan, L.5
Sad, S.6
-
4
-
-
84862175306
-
Dichotomy between RIP1- and RIP3-mediated necroptosis in tumor necrosis factor-a-induced shock
-
Linkermann, A., J. H. Bräsen, F. De Zen, R. Weinlich, R. A. Schwendener, D. R. Green, U. Kunzendorf, and S. Krautwald. 2012. Dichotomy between RIP1- and RIP3-mediated necroptosis in tumor necrosis factor-a-induced shock. Mol. Med. 18:577-586.
-
(2012)
Mol. Med.
, vol.18
, pp. 577-586
-
-
Linkermann, A.1
Bräsen, J.H.2
De Zen, F.3
Weinlich, R.4
Schwendener, R.A.5
Green, D.R.6
Kunzendorf, U.7
Krautwald, S.8
-
5
-
-
84255162797
-
RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome
-
Duprez, L., N. Takahashi, F. Van Hauwermeiren, B. Vandendriessche, V. Goossens, T. Vanden Berghe, W. Declercq, C. Libert, A. Cauwels, and P. Vandenabeele. 2011. RIP kinase-dependent necrosis drives lethal systemic inflammatory response syndrome. Immunity 35:908-918.
-
(2011)
Immunity
, vol.35
, pp. 908-918
-
-
Duprez, L.1
Takahashi, N.2
Van Hauwermeiren, F.3
Vandendriessche, B.4
Goossens, V.5
Vanden Berghe, T.6
Declercq, W.7
Libert, C.8
Cauwels, A.9
Vandenabeele, P.10
-
6
-
-
4444324090
-
Apoptosis and disease: A life or death decision
-
MacFarlane, M., and A. C. Williams. 2004. Apoptosis and disease: a life or death decision. EMBO Rep. 5:674-678.
-
(2004)
EMBO Rep.
, vol.5
, pp. 674-678
-
-
MacFarlane, M.1
Williams, A.C.2
-
7
-
-
77957105977
-
Molecular mechanisms of necroptosis: An ordered cellular explosion
-
Vandenabeele, P., L. Galluzzi, T. Vanden Berghe, and G. Kroemer. 2010. Molecular mechanisms of necroptosis: an ordered cellular explosion. Nat. Rev. Mol. Cell Biol. 11:700-714.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 700-714
-
-
Vandenabeele, P.1
Galluzzi, L.2
Vanden Berghe, T.3
Kroemer, G.4
-
8
-
-
66449133280
-
Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation
-
Cho, Y. S., S. Challa, D. Moquin, R. Genga, T. D. Ray, M. Guildford, and F. K.-M. Chan. 2009. Phosphorylation-driven assembly of the RIP1-RIP3 complex regulates programmed necrosis and virus-induced inflammation. Cell 137:1112-1123.
-
(2009)
Cell
, vol.137
, pp. 1112-1123
-
-
Cho, Y.S.1
Challa, S.2
Moquin, D.3
Genga, R.4
Ray, T.D.5
Guildford, M.6
Chan, F.K.-M.7
-
9
-
-
68249113997
-
DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-kappaB
-
Rebsamen, M., L. X. Heinz, E. Meylan, M.-C. Michallet, K. Schroder, K. Hofmann, J. Vazquez, C. A. Benedict, and J. Tschopp. 2009. DAI/ZBP1 recruits RIP1 and RIP3 through RIP homotypic interaction motifs to activate NF-kappaB. EMBO Rep. 10:916-922.
-
(2009)
EMBO Rep.
, vol.10
, pp. 916-922
-
-
Rebsamen, M.1
Heinz, L.X.2
Meylan, E.3
Michallet, M.-C.4
Schroder, K.5
Hofmann, K.6
Vazquez, J.7
Benedict, C.A.8
Tschopp, J.9
-
10
-
-
84871028547
-
CIAP1 and cIAP2 limit macrophage necroptosis by inhibiting Rip1 and Rip3 activation
-
McComb, S., H. H. Cheung, R. G. Korneluk, S. Wang, L. Krishnan, and S. Sad. 2012. cIAP1 and cIAP2 limit macrophage necroptosis by inhibiting Rip1 and Rip3 activation. Cell Death Differ. 19:1791-1801.
-
(2012)
Cell Death Differ.
, vol.19
, pp. 1791-1801
-
-
McComb, S.1
Cheung, H.H.2
Korneluk, R.G.3
Wang, S.4
Krishnan, L.5
Sad, S.6
-
11
-
-
79952811804
-
RIP3 mediates the embryonic lethality of caspase-8-deficient mice
-
Kaiser, W. J., J. W. Upton, A. B. Long, D. Livingston-Rosanoff, L. P. Daley-Bauer, R. Hakem, T. Caspary, and E. S. Mocarski. 2011. RIP3 mediates the embryonic lethality of caspase-8-deficient mice. Nature 471:368-372.
-
(2011)
Nature
, vol.471
, pp. 368-372
-
-
Kaiser, W.J.1
Upton, J.W.2
Long, A.B.3
Livingston-Rosanoff, D.4
Daley-Bauer, L.P.5
Hakem, R.6
Caspary, T.7
Mocarski, E.S.8
-
12
-
-
33644840693
-
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury
-
Degterev, A., Z. Huang, M. Boyce, Y. Li, P. Jagtap, N. Mizushima, G. D. Cuny, T. J. Mitchison, M. A. Moskowitz, and J. Yuan. 2005. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nat. Chem. Biol. 1:112-119.
-
(2005)
Nat. Chem. Biol.
, vol.1
, pp. 112-119
-
-
Degterev, A.1
Huang, Z.2
Boyce, M.3
Li, Y.4
Jagtap, P.5
Mizushima, N.6
Cuny, G.D.7
Mitchison, T.J.8
Moskowitz, M.A.9
Yuan, J.10
-
13
-
-
0033214236
-
Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis
-
Lin, Y., A. Devin, Y. Rodriguez, and Z. G. Liu. 1999. Cleavage of the death domain kinase RIP by caspase-8 prompts TNF-induced apoptosis. Genes Dev. 13:2514-2526.
-
(1999)
Genes Dev.
, vol.13
, pp. 2514-2526
-
-
Lin, Y.1
Devin, A.2
Rodriguez, Y.3
Liu, Z.G.4
-
14
-
-
84861712290
-
Survival function of the FADDCASPASE-8-cFLIP (L) complex
-
Dillon, C. P., A. Oberst, R. Weinlich, L. J. Janke, T.-B. Kang, T. Ben-Moshe, T. W. Mak, D. Wallach, and D. R. Green. 2012. Survival function of the FADDCASPASE-8-cFLIP (L) complex. Cell Rep. 1:401-407.
-
(2012)
Cell Rep.
, vol.1
, pp. 401-407
-
-
Dillon, C.P.1
Oberst, A.2
Weinlich, R.3
Janke, L.J.4
Kang, T.-B.5
Ben-Moshe, T.6
Mak, T.W.7
Wallach, D.8
Green, D.R.9
-
15
-
-
78650175369
-
ZVADinduced necroptosis in L929 cells depends on autocrine production of TNFa mediated by the PKC-MAPKs-AP-1 pathway
-
Wu, Y.-T., H.-L. Tan, Q. Huang, X.-J. Sun, X. Zhu, and H.-M. Shen. 2011. zVADinduced necroptosis in L929 cells depends on autocrine production of TNFa mediated by the PKC-MAPKs-AP-1 pathway. Cell Death Differ. 18:26-37.
-
(2011)
Cell Death Differ.
, vol.18
, pp. 26-37
-
-
Wu, Y.-T.1
Tan, H.-L.2
Huang, Q.3
Sun, X.-J.4
Zhu, X.5
Shen, H.-M.6
-
16
-
-
0037115158
-
Reactive oxygen species and cell signaling: Respiratory burst in macrophage signaling
-
Forman, H. J., and M. Torres. 2002. Reactive oxygen species and cell signaling: respiratory burst in macrophage signaling. Am. J. Respir. Crit. CareMed. 166:S4-S8.
-
(2002)
Am. J. Respir. Crit. CareMed.
, vol.166
-
-
Forman, H.J.1
Torres, M.2
-
17
-
-
12444315984
-
Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: When reaction mechanism is more important than specificity
-
Rozman-Pungercar, J., N. Kopitar-Jerala, M. Bogyo, D. Turk, O. Vasiljeva, I. Stefe, P. Vandenabeele, D. Brömme, V. Puizdar, M. Fonović, et al. 2003. Inhibition of papain-like cysteine proteases and legumain by caspase-specific inhibitors: when reaction mechanism is more important than specificity. Cell Death Differ. 10:881-888.
-
(2003)
Cell Death Differ.
, vol.10
, pp. 881-888
-
-
Rozman-Pungercar, J.1
Kopitar-Jerala, N.2
Bogyo, M.3
Turk, D.4
Vasiljeva, O.5
Stefe, I.6
Vandenabeele, P.7
Brömme, D.8
Puizdar, V.9
Fonović, M.10
-
18
-
-
70449564367
-
Versatile assays for high throughput screening for activators or inhibitors of intracellular proteases and their cellular regulators
-
Hayashi, H., M. Cuddy, V. C.-W. Shu, K. W. Yip, C. Madiraju, P. Diaz, T. Matsuyama, M. Kaibara, K. Taniyama, S. Vasile, et al. 2009. Versatile assays for high throughput screening for activators or inhibitors of intracellular proteases and their cellular regulators. PLoS ONE 4:e7655.
-
(2009)
PLoS ONE
, vol.4
-
-
Hayashi, H.1
Cuddy, M.2
Shu, V.C.-W.3
Yip, K.W.4
Madiraju, C.5
Diaz, P.6
Matsuyama, T.7
Kaibara, M.8
Taniyama, K.9
Vasile, S.10
-
19
-
-
0036661140
-
Modulation of the endosomal and lysosomal distribution of cathepsins B, L and S in human monocytes/macrophages
-
Schmid, H., R. Sauerbrei, G. Schwarz, E. Weber, H. Kalbacher, and C. Driessen. 2002. Modulation of the endosomal and lysosomal distribution of cathepsins B, L and S in human monocytes/macrophages. Biol. Chem. 383:1277-1283.
-
(2002)
Biol. Chem.
, vol.383
, pp. 1277-1283
-
-
Schmid, H.1
Sauerbrei, R.2
Schwarz, G.3
Weber, E.4
Kalbacher, H.5
Driessen, C.6
-
20
-
-
0037454948
-
Differential regulation of cathepsin S and cathepsin L in interferon g-treated macrophages
-
Beers, C., K. Honey, S. Fink, K. Forbush, and A. Rudensky. 2003. Differential regulation of cathepsin S and cathepsin L in interferon g-treated macrophages. J. Exp. Med. 197:169-179.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 169-179
-
-
Beers, C.1
Honey, K.2
Fink, S.3
Forbush, K.4
Rudensky, A.5
-
21
-
-
33645703930
-
Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NFkappaB activation. [Published erratum appears in 2006 Nat. Cell Biol. 8:424.]
-
Wu, C.-J., D. B. Conze, T. Li, S. M. Srinivasula, and J. D. Ashwell. 2006. Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NFkappaB activation. [Published erratum appears in 2006 Nat. Cell Biol. 8:424.] Nat. Cell Biol. 8:398-406.
-
(2006)
Nat. Cell Biol.
, vol.8
, pp. 398-406
-
-
Wu, C.-J.1
Conze, D.B.2
Li, T.3
Srinivasula, S.M.4
Ashwell, J.D.5
-
22
-
-
77956184308
-
Applications of the Restriction Free (RF) cloning procedure for molecular manipulations and protein expression
-
Unger, T., Y. Jacobovitch, A. Dantes, R. Bernheim, and Y. Peleg. 2010. Applications of the Restriction Free (RF) cloning procedure for molecular manipulations and protein expression. J. Struct. Biol. 172:34-44.
-
(2010)
J. Struct. Biol.
, vol.172
, pp. 34-44
-
-
Unger, T.1
Jacobovitch, Y.2
Dantes, A.3
Bernheim, R.4
Peleg, Y.5
-
23
-
-
43949085388
-
Autophagy plays a protective role during zVAD-induced necrotic cell death
-
Wu, Y.-T., H.-L. Tan, Q. Huang, Y.-S. Kim, N. Pan, W.-Y. Ong, Z. G. Liu, C.-N. Ong, and H.-M. Shen. 2008. Autophagy plays a protective role during zVAD-induced necrotic cell death. Autophagy 4:457-466.
-
(2008)
Autophagy
, vol.4
, pp. 457-466
-
-
Wu, Y.-T.1
Tan, H.-L.2
Huang, Q.3
Kim, Y.-S.4
Pan, N.5
Ong, W.-Y.6
Liu, Z.G.7
Ong, C.-N.8
Shen, H.-M.9
-
24
-
-
0034764403
-
Pan-caspase inhibitor zVAD enhances cell death in RAW246.7 macrophages
-
Kim, S. O., and J. Han. 2001. Pan-caspase inhibitor zVAD enhances cell death in RAW246.7 macrophages. J. Endotoxin Res. 7:292-296.
-
(2001)
J. Endotoxin Res.
, vol.7
, pp. 292-296
-
-
Kim, S.O.1
Han, J.2
-
25
-
-
84055181328
-
Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway
-
He, S., Y. Liang, F. Shao, and X. Wang. 2011. Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3-mediated pathway. Proc. Natl. Acad. Sci. USA 108:20054-20059.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 20054-20059
-
-
He, S.1
Liang, Y.2
Shao, F.3
Wang, X.4
-
26
-
-
77951251430
-
Necroptosis as an alternative form of programmed cell death
-
Christofferson, D. E., and J. Yuan. 2010. Necroptosis as an alternative form of programmed cell death. Curr. Opin. Cell Biol. 22:263-268.
-
(2010)
Curr. Opin. Cell Biol.
, vol.22
, pp. 263-268
-
-
Christofferson, D.E.1
Yuan, J.2
-
27
-
-
84856231635
-
Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways
-
Mocarski, E. S., J. W. Upton, and W. J. Kaiser. 2012. Viral infection and the evolution of caspase 8-regulated apoptotic and necrotic death pathways. Nat. Rev. Immunol. 12:79-88.
-
(2012)
Nat. Rev. Immunol.
, vol.12
, pp. 79-88
-
-
Mocarski, E.S.1
Upton, J.W.2
Kaiser, W.J.3
-
28
-
-
67650638892
-
RIP kinases at the crossroads of cell death and survival
-
Declercq, W., T. Vanden Berghe, and P. Vandenabeele. 2009. RIP kinases at the crossroads of cell death and survival. Cell 138:229-232.
-
(2009)
Cell
, vol.138
, pp. 229-232
-
-
Declercq, W.1
Vanden Berghe, T.2
Vandenabeele, P.3
-
29
-
-
67650812332
-
RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis
-
Zhang, D.-W., J. Shao, J. Lin, N. Zhang, B.-J. Lu, S.-C. Lin, M.-Q. Dong, and J. Han. 2009. RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis. Science 325:332-336.
-
(2009)
Science
, vol.325
, pp. 332-336
-
-
Zhang, D.-W.1
Shao, J.2
Lin, J.3
Zhang, N.4
Lu, B.-J.5
Lin, S.-C.6
Dong, M.-Q.7
Han, J.8
-
31
-
-
70450222302
-
The role of lysosomal rupture in neuronal death
-
Yamashima, T., and S. Oikawa. 2009. The role of lysosomal rupture in neuronal death. Prog. Neurobiol. 89:343-358.
-
(2009)
Prog. Neurobiol.
, vol.89
, pp. 343-358
-
-
Yamashima, T.1
Oikawa, S.2
-
32
-
-
82755197676
-
Lysosomes and lysosomal cathepsins in cell death
-
Repnik, U., V. Stoka, V. Turk, and B. Turk. 2012. Lysosomes and lysosomal cathepsins in cell death. Biochim. Biophys. Acta 1824:22-33.
-
(2012)
Biochim. Biophys. Acta
, vol.1824
, pp. 22-33
-
-
Repnik, U.1
Stoka, V.2
Turk, V.3
Turk, B.4
-
33
-
-
0033756474
-
Cathepsin B contributes to TNF-alphamediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c
-
Guicciardi, M. E., J. Deussing, H. Miyoshi, S. F. Bronk, P. A. Svingen, C. Peters, S. H. Kaufmann, and G. J. Gores. 2000. Cathepsin B contributes to TNF-alphamediated hepatocyte apoptosis by promoting mitochondrial release of cytochrome c. J. Clin. Invest. 106:1127-1137.
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 1127-1137
-
-
Guicciardi, M.E.1
Deussing, J.2
Miyoshi, H.3
Bronk, S.F.4
Svingen, P.A.5
Peters, C.6
Kaufmann, S.H.7
Gores, G.J.8
-
34
-
-
0942265544
-
Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of Bid by multiple papain-like lysosomal cathepsins
-
Cirman, T., K. Oresić, G. D. Mazovec, V. Turk, J. C. Reed, R. M. Myers, G. S. Salvesen, and B. Turk. 2004. Selective disruption of lysosomes in HeLa cells triggers apoptosis mediated by cleavage of Bid by multiple papain-like lysosomal cathepsins. J. Biol. Chem. 279:3578-3587.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 3578-3587
-
-
Cirman, T.1
Oresić, K.2
Mazovec, G.D.3
Turk, V.4
Reed, J.C.5
Myers, R.M.6
Salvesen, G.S.7
Turk, B.8
-
35
-
-
84856759660
-
Many stimuli pull the necrotic trigger, an overview
-
Vanlangenakker, N., T. Vanden Berghe, and P. Vandenabeele. 2012. Many stimuli pull the necrotic trigger, an overview. Cell Death Differ. 19:75-86.
-
(2012)
Cell Death Differ.
, vol.19
, pp. 75-86
-
-
Vanlangenakker, N.1
Vanden Berghe, T.2
Vandenabeele, P.3
-
36
-
-
27744561393
-
Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-κB activation but does not contribute to interferon regulatory factor 3 activation
-
Cusson-Hermance, N., S. Khurana, T. H. Lee, K. A. Fitzgerald, and M. A. Kelliher. 2005. Rip1 mediates the Trif-dependent toll-like receptor 3- and 4-induced NF-κB activation but does not contribute to interferon regulatory factor 3 activation. J. Biol. Chem. 280:36560-36566.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 36560-36566
-
-
Cusson-Hermance, N.1
Khurana, S.2
Lee, T.H.3
Fitzgerald, K.A.4
Kelliher, M.A.5
-
37
-
-
40949134086
-
TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferonbeta
-
Kagan, J. C., T. Su, T. Horng, A. Chow, S. Akira, and R. Medzhitov. 2008. TRAM couples endocytosis of Toll-like receptor 4 to the induction of interferonbeta. Nat. Immunol. 9:361-368.
-
(2008)
Nat. Immunol.
, vol.9
, pp. 361-368
-
-
Kagan, J.C.1
Su, T.2
Horng, T.3
Chow, A.4
Akira, S.5
Medzhitov, R.6
-
38
-
-
79952770123
-
RIG-I RNA helicase activation of IRF3 transcription factor is negatively regulated by caspase-8-mediated cleavage of the RIP1 protein
-
Rajput, A., A. Kovalenko, K. Bogdanov, S.-H. Yang, T.-B. Kang, J.-C. Kim, J. Du, and D. Wallach. 2011. RIG-I RNA helicase activation of IRF3 transcription factor is negatively regulated by caspase-8-mediated cleavage of the RIP1 protein. Immunity 34:340-351.
-
(2011)
Immunity
, vol.34
, pp. 340-351
-
-
Rajput, A.1
Kovalenko, A.2
Bogdanov, K.3
Yang, S.-H.4
Kang, T.-B.5
Kim, J.-C.6
Du, J.7
Wallach, D.8
-
39
-
-
84867625960
-
Active cathepsins B, L, and S in murine and human pancreatitis
-
Lyo, V., F. Cattaruzza, T. N. Kim, A. W. Walker, M. Paulick, D. Cox, J. Cloyd, J. Buxbaum, J. Ostroff, M. Bogyo, et al. 2012. Active cathepsins B, L, and S in murine and human pancreatitis. Am. J. Physiol. Gastrointest. Liver Physiol. 303:G894-G903.
-
(2012)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.303
-
-
Lyo, V.1
Cattaruzza, F.2
Kim, T.N.3
Walker, A.W.4
Paulick, M.5
Cox, D.6
Cloyd, J.7
Buxbaum, J.8
Ostroff, J.9
Bogyo, M.10
-
40
-
-
33748710916
-
Cathepsins B, L and D in inflammatory bowel disease macrophages and potential therapeutic effects of cathepsin inhibition in vivo
-
Menzel, K., M. Hausmann, F. Obermeier, K. Schreiter, N. Dunger, F. Bataille, W. Falk, J. Scholmerich, H. Herfarth, and G. Rogler. 2006. Cathepsins B, L and D in inflammatory bowel disease macrophages and potential therapeutic effects of cathepsin inhibition in vivo. Clin. Exp. Immunol. 146:169-180.
-
(2006)
Clin. Exp. Immunol.
, vol.146
, pp. 169-180
-
-
Menzel, K.1
Hausmann, M.2
Obermeier, F.3
Schreiter, K.4
Dunger, N.5
Bataille, F.6
Falk, W.7
Scholmerich, J.8
Herfarth, H.9
Rogler, G.10
-
41
-
-
84892431448
-
Cysteinyl cathepsins: Multifunctional enzymes in cardiovascular disease
-
Li, X., Z. Liu, Z. Cheng, and X. Cheng. 2012. Cysteinyl cathepsins: multifunctional enzymes in cardiovascular disease. Chonnam Med. J. 48:77-85.
-
(2012)
Chonnam Med. J.
, vol.48
, pp. 77-85
-
-
Li, X.1
Liu, Z.2
Cheng, Z.3
Cheng, X.4
-
42
-
-
33749017931
-
Cysteine cathepsins: Multifunctional enzymes in cancer
-
Mohamed, M. M., and B. F. Sloane. 2006. Cysteine cathepsins: multifunctional enzymes in cancer. Nat. Rev. Cancer 6:764-775
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 764-775
-
-
Mohamed, M.M.1
Sloane, B.F.2
|