-
1
-
-
84872967522
-
Cancer Statistics, 2013
-
Siegel, R., Naishadham, D., and Jemal, A. (2013) Cancer Statistics, 2013 Ca-Cancer J. Clin. 63, 11-30 10.3322/caac.21166
-
(2013)
Ca-Cancer J. Clin.
, vol.63
, pp. 11-30
-
-
Siegel, R.1
Naishadham, D.2
Jemal, A.3
-
2
-
-
84920837701
-
Cancer Statistics, 2015
-
Siegel, R. L., Miller, K. D., and Jemal, A. (2015) Cancer Statistics, 2015 Ca-Cancer J. Clin. 65, 5-29 10.3322/caac.21254
-
(2015)
Ca-Cancer J. Clin.
, vol.65
, pp. 5-29
-
-
Siegel, R.L.1
Miller, K.D.2
Jemal, A.3
-
3
-
-
84884535896
-
Cancer drug resistance: An evolving paradigm
-
Holohan, C., Van Schaeybroeck, S., Longley, D. B., and Johnston, P. G. (2013) Cancer drug resistance: an evolving paradigm Nat. Rev. Cancer 13, 714-726 10.1038/nrc3599
-
(2013)
Nat. Rev. Cancer
, vol.13
, pp. 714-726
-
-
Holohan, C.1
Van Schaeybroeck, S.2
Longley, D.B.3
Johnston, P.G.4
-
4
-
-
82255192310
-
Pretreatment Mitochondrial Priming Correlates with Clinical Response to Cytotoxic Chemotherapy
-
Chonghaile, T. N., Sarosiek, K. A., Vo, T.-T., Ryan, J. A., Tammareddi, A., Moore, V. D. G., Deng, J., Anderson, K. C., Richardson, P., Tai, Y.-T., Mitsiades, C. S., Matulonis, U. A., Drapkin, R., Stone, R., DeAngelo, D. J., McConkey, D. J., Sallan, S. E., Silverman, L., Hirsch, M. S., Carrasco, D. R., and Letai, A. (2011) Pretreatment Mitochondrial Priming Correlates with Clinical Response to Cytotoxic Chemotherapy Science 334, 1129-1133 10.1126/science.1206727
-
(2011)
Science
, vol.334
, pp. 1129-1133
-
-
Chonghaile, T.N.1
Sarosiek, K.A.2
Vo, T.-T.3
Ryan, J.A.4
Tammareddi, A.5
Moore, V.D.G.6
Deng, J.7
Anderson, K.C.8
Richardson, P.9
Tai, Y.-T.10
Mitsiades, C.S.11
Matulonis, U.A.12
Drapkin, R.13
Stone, R.14
DeAngelo, D.J.15
McConkey, D.J.16
Sallan, S.E.17
Silverman, L.18
Hirsch, M.S.19
Carrasco, D.R.20
Letai, A.21
more..
-
5
-
-
84890909335
-
Control of apoptosis by the BCL-2 protein family: Implications for physiology and therapy
-
Czabotar, P. E., Lessene, G., Strasser, A., and Adams, J. M. (2014) Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy Nat. Rev. Mol. Cell Biol. 15, 49-63 10.1038/nrm3722
-
(2014)
Nat. Rev. Mol. Cell Biol.
, vol.15
, pp. 49-63
-
-
Czabotar, P.E.1
Lessene, G.2
Strasser, A.3
Adams, J.M.4
-
6
-
-
0842269242
-
P53 family members and chemoresistance in cancer: What we know and what we need to know
-
Gasco, M. and Crook, T. (2003) p53 family members and chemoresistance in cancer: what we know and what we need to know Drug Resist. Updates 6, 323-328 10.1016/j.drup.2003.11.001
-
(2003)
Drug Resist. Updates
, vol.6
, pp. 323-328
-
-
Gasco, M.1
Crook, T.2
-
7
-
-
84870026354
-
Rules for Identifying Potentially Reactive or Promiscuous Compounds
-
Bruns, R. F. and Watson, I. A. (2012) Rules for Identifying Potentially Reactive or Promiscuous Compounds J. Med. Chem. 55, 9763-9772 10.1021/jm301008n
-
(2012)
J. Med. Chem.
, vol.55
, pp. 9763-9772
-
-
Bruns, R.F.1
Watson, I.A.2
-
8
-
-
77950571108
-
New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays
-
Baell, J. B. and Holloway, G. A. (2010) New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays J. Med. Chem. 53, 2719-2740 10.1021/jm901137j
-
(2010)
J. Med. Chem.
, vol.53
, pp. 2719-2740
-
-
Baell, J.B.1
Holloway, G.A.2
-
9
-
-
80955157310
-
Bond stability of the "undesirable" heteroatom-heteroatom molecular moieties for high-throughput screening libraries
-
Yu, B. and Reynisson, J. (2011) Bond stability of the "undesirable" heteroatom-heteroatom molecular moieties for high-throughput screening libraries Eur. J. Med. Chem. 46, 5833-5837 10.1016/j.ejmech.2011.09.044
-
(2011)
Eur. J. Med. Chem.
, vol.46
, pp. 5833-5837
-
-
Yu, B.1
Reynisson, J.2
-
10
-
-
78649887837
-
-
Second ed. World Health Organization, Geneva, Switzerland
-
Guidelines for the Treatment of Malaria (2010), Second ed., World Health Organization, Geneva, Switzerland.
-
(2010)
Guidelines for the Treatment of Malaria
-
-
-
11
-
-
84855554316
-
Antitumor Activity of Artemisinin and Its Derivatives: From a Well-Known Antimalarial Agent to a Potential Anticancer Drug
-
Crespo-Ortiz, M. P. and Wei, M. Q. (2012) Antitumor Activity of Artemisinin and Its Derivatives: From a Well-Known Antimalarial Agent to a Potential Anticancer Drug J. Biomed. Biotechnol. 2012, 1-18 10.1155/2012/247597
-
(2012)
J. Biomed. Biotechnol.
, vol.2012
, pp. 1-18
-
-
Crespo-Ortiz, M.P.1
Wei, M.Q.2
-
12
-
-
84927757551
-
A Randomised, Double Blind, Placebo-Controlled Pilot Study of Oral Artesunate Therapy for Colorectal Cancer
-
Krishna, S., Ganapathi, S., Ster, I. C., Saeed, M. E. M., Cowan, M., Finlayson, C., Kovacsevics, H., Jansen, H., Kremsner, P. G., Efferth, T., and Kumar, D. (2015) A Randomised, Double Blind, Placebo-Controlled Pilot Study of Oral Artesunate Therapy for Colorectal Cancer EBioMedicine 2, 82-90 10.1016/j.ebiom.2014.11.010
-
(2015)
EBioMedicine
, vol.2
, pp. 82-90
-
-
Krishna, S.1
Ganapathi, S.2
Ster, I.C.3
Saeed, M.E.M.4
Cowan, M.5
Finlayson, C.6
Kovacsevics, H.7
Jansen, H.8
Kremsner, P.G.9
Efferth, T.10
Kumar, D.11
-
13
-
-
77955552792
-
Synthesis of an antitumor active endoperoxide from 11-keto-β-boswellic acid
-
Csuk, R., Niesen-Barthel, A., Barthel, A., Kluge, R., and Ströhl, D. (2010) Synthesis of an antitumor active endoperoxide from 11-keto-β-boswellic acid Eur. J. Med. Chem. 45, 3840-3843 10.1016/j.ejmech.2010.05.036
-
(2010)
Eur. J. Med. Chem.
, vol.45
, pp. 3840-3843
-
-
Csuk, R.1
Niesen-Barthel, A.2
Barthel, A.3
Kluge, R.4
Ströhl, D.5
-
14
-
-
0026321454
-
Cytotoxic Five-Membered Cyclic Peroxides from a Plakortis Sponge
-
Davidson, B. S. (1991) Cytotoxic Five-Membered Cyclic Peroxides from a Plakortis Sponge J. Org. Chem. 56, 6722-6724 10.1021/jo00023a048
-
(1991)
J. Org. Chem.
, vol.56
, pp. 6722-6724
-
-
Davidson, B.S.1
-
15
-
-
0021948308
-
Human Acute Leukemia Cell Line with the t(4;11) Chromosomal Rearrangement Exhibits B Lineage and Monocytic Characteristics
-
Stong, R. C., Korsmeyer, S. J., Parkin, J. L., Arthur, D. C., and Kersey, J. H. (1985) Human Acute Leukemia Cell Line With the t(4;11) Chromosomal Rearrangement Exhibits B Lineage and Monocytic Characteristics Blood 65, 21-31
-
(1985)
Blood
, vol.65
, pp. 21-31
-
-
Stong, R.C.1
Korsmeyer, S.J.2
Parkin, J.L.3
Arthur, D.C.4
Kersey, J.H.5
-
16
-
-
84861541814
-
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
-
Dixon, S. J., Lemberg, K. M., Lamprecht, M. R., Skouta, R., Zaitsev, E. M., Gleason, C. E., Patel, D. N., Bauer, A. J., Cantley, A. M., Yang, W. S., Morrison, B., III, and Stockwell, B. R. (2012) Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death Cell 149, 1060-1072 10.1016/j.cell.2012.03.042
-
(2012)
Cell
, vol.149
, pp. 1060-1072
-
-
Dixon, S.J.1
Lemberg, K.M.2
Lamprecht, M.R.3
Skouta, R.4
Zaitsev, E.M.5
Gleason, C.E.6
Patel, D.N.7
Bauer, A.J.8
Cantley, A.M.9
Yang, W.S.10
Morrison, B.11
Stockwell, B.R.12
-
17
-
-
27144520561
-
Synthesis of 1,2-Dioxolanes by Annulation Reactions of Peroxycarbenium Ions with Alkenes
-
Ramirez, A. and Woerpel, K. A. (2005) Synthesis of 1,2-Dioxolanes by Annulation Reactions of Peroxycarbenium Ions with Alkenes Org. Lett. 7, 4617-4620 10.1021/ol051703u
-
(2005)
Org. Lett.
, vol.7
, pp. 4617-4620
-
-
Ramirez, A.1
Woerpel, K.A.2
-
18
-
-
64349109464
-
A Broadly Applicable Mild Method for the Synthesis of gem-Diperoxides from Corresponding Ketones or 1,3-Dioxolanes
-
Li, Y., Hao, H.-D., Zhang, Q., and Wu, Y. (2009) A Broadly Applicable Mild Method for the Synthesis of gem-Diperoxides from Corresponding Ketones or 1,3-Dioxolanes Org. Lett. 11, 1615-1618 10.1021/ol900262t
-
(2009)
Org. Lett.
, vol.11
, pp. 1615-1618
-
-
Li, Y.1
Hao, H.-D.2
Zhang, Q.3
Wu, Y.4
-
19
-
-
84892685001
-
Regulation of Ferroptotic Cancer Cell Death by GPX4
-
Yang, W. S., SriRamaratnam, R., Welsch, M. E., Shimada, K., Skouta, R., Viswanathan, V. S., Cheah, J. H., Clemons, P. A., Shamji, A. F., Clish, C. B., Brown, L. M., Girotti, A. W., Cornish, V. W., Schreiber, S. L., and Stockwell, B. R. (2014) Regulation of Ferroptotic Cancer Cell Death by GPX4 Cell 156, 317-331 10.1016/j.cell.2013.12.010
-
(2014)
Cell
, vol.156
, pp. 317-331
-
-
Yang, W.S.1
SriRamaratnam, R.2
Welsch, M.E.3
Shimada, K.4
Skouta, R.5
Viswanathan, V.S.6
Cheah, J.H.7
Clemons, P.A.8
Shamji, A.F.9
Clish, C.B.10
Brown, L.M.11
Girotti, A.W.12
Cornish, V.W.13
Schreiber, S.L.14
Stockwell, B.R.15
-
20
-
-
84861539740
-
Preclinical Predictors of Anticancer Drug Efficacy: Critical Assessment with Emphasis on Whether Nanomolar Potency Should Be Required of Candidate Agents
-
Wong, C. C., Cheng, K.-W., and Rigas, B. (2012) Preclinical Predictors of Anticancer Drug Efficacy: Critical Assessment with Emphasis on Whether Nanomolar Potency Should Be Required of Candidate Agents J. Pharmacol. Exp. Ther. 341, 572-578 10.1124/jpet.112.191957
-
(2012)
J. Pharmacol. Exp. Ther.
, vol.341
, pp. 572-578
-
-
Wong, C.C.1
Cheng, K.-W.2
Rigas, B.3
-
21
-
-
77952117909
-
Analysis of Food and Drug Administration-Approved Anticancer Agents in the NCI60 Panel of Human Tumor Cell Lines
-
Holbeck, S. L., Collins, J. M., and Doroshow, J. H. (2010) Analysis of Food and Drug Administration-Approved Anticancer Agents in the NCI60 Panel of Human Tumor Cell Lines Mol. Cancer Ther. 9, 1451-1460 10.1158/1535-7163.MCT-10-0106
-
(2010)
Mol. Cancer Ther.
, vol.9
, pp. 1451-1460
-
-
Holbeck, S.L.1
Collins, J.M.2
Doroshow, J.H.3
-
22
-
-
84886509950
-
Metrics other than potency reveal systematic variation in responses to cancer drugs
-
Fallahi-Sichani, M., Honarnejad, S., Heiser, L. M., Gray, J. W., and Sorger, P. K. (2013) Metrics other than potency reveal systematic variation in responses to cancer drugs Nat. Chem. Biol. 9, 708-714 10.1038/nchembio.1337
-
(2013)
Nat. Chem. Biol.
, vol.9
, pp. 708-714
-
-
Fallahi-Sichani, M.1
Honarnejad, S.2
Heiser, L.M.3
Gray, J.W.4
Sorger, P.K.5
-
23
-
-
84863910171
-
CellMiner: A Web-Based Suite of Genomic and Pharmacologic Tools to Explore Transcript and Drug Patterns in the NCI-60 Cell Line Set
-
Reinhold, W. C., Sunshine, M., Liu, H., Varma, S., Kohn, K. W., Morris, J., Doroshow, J., and Pommier, Y. (2012) CellMiner: A Web-Based Suite of Genomic and Pharmacologic Tools to Explore Transcript and Drug Patterns in the NCI-60 Cell Line Set Cancer Res. 72, 3499-3511 10.1158/0008-5472.CAN-12-1370
-
(2012)
Cancer Res.
, vol.72
, pp. 3499-3511
-
-
Reinhold, W.C.1
Sunshine, M.2
Liu, H.3
Varma, S.4
Kohn, K.W.5
Morris, J.6
Doroshow, J.7
Pommier, Y.8
-
24
-
-
84879759054
-
Organometallic Iridium(III) Anticancer Complexes with New Mechanisms of Action: NCI-60 Screening, Mitochondrial Targeting, and Apoptosis
-
Hearn, J. M., Romero-Canelón, I., Qamar, B., Liu, Z., Hands-Portman, I., and Sadler, P. J. (2013) Organometallic Iridium(III) Anticancer Complexes with New Mechanisms of Action: NCI-60 Screening, Mitochondrial Targeting, and Apoptosis ACS Chem. Biol. 8, 1335-1343 10.1021/cb400070a
-
(2013)
ACS Chem. Biol.
, vol.8
, pp. 1335-1343
-
-
Hearn, J.M.1
Romero-Canelón, I.2
Qamar, B.3
Liu, Z.4
Hands-Portman, I.5
Sadler, P.J.6
-
25
-
-
78650448417
-
Genome-Wide mRNA and microRNA Profiling of the NCI 60 Cell-Line Screen and Comparison of FdUMP[10] with Fluorouracil, Floxuridine, and Topoisomerase 1 Poisons
-
Gmeiner, W. H., Reinhold, W. C., and Pommier, Y. (2010) Genome-Wide mRNA and microRNA Profiling of the NCI 60 Cell-Line Screen and Comparison of FdUMP[10] with Fluorouracil, Floxuridine, and Topoisomerase 1 Poisons Mol. Cancer Ther. 9, 3105-3114 10.1158/1535-7163.MCT-10-0674
-
(2010)
Mol. Cancer Ther.
, vol.9
, pp. 3105-3114
-
-
Gmeiner, W.H.1
Reinhold, W.C.2
Pommier, Y.3
-
26
-
-
67650687092
-
CellMiner: A relational database and query tool for the NCI-60 cancer cell lines
-
Shankavaram, U., Varma, S., Kane, D., Sunshine, M., Chary, K., Reinhold, W., Pommier, Y., and Weinstein, J. (2009) CellMiner: a relational database and query tool for the NCI-60 cancer cell lines BMC Genomics 10, 277 10.1186/1471-2164-10-277
-
(2009)
BMC Genomics
, vol.10
, pp. 277
-
-
Shankavaram, U.1
Varma, S.2
Kane, D.3
Sunshine, M.4
Chary, K.5
Reinhold, W.6
Pommier, Y.7
Weinstein, J.8
-
27
-
-
79960427057
-
Selective killing of cancer cells by a small molecule targeting the stress response to ROS
-
Raj, L., Ide, T., Gurkar, A. U., Foley, M., Schenone, M., Li, X., Tolliday, N. J., Golub, T. R., Carr, S. A., Shamji, A. F., Stern, A. M., Mandinova, A., Schreiber, S. L., and Lee, S. W. (2011) Selective killing of cancer cells by a small molecule targeting the stress response to ROS Nature 475, 231-234 10.1038/nature10167
-
(2011)
Nature
, vol.475
, pp. 231-234
-
-
Raj, L.1
Ide, T.2
Gurkar, A.U.3
Foley, M.4
Schenone, M.5
Li, X.6
Tolliday, N.J.7
Golub, T.R.8
Carr, S.A.9
Shamji, A.F.10
Stern, A.M.11
Mandinova, A.12
Schreiber, S.L.13
Lee, S.W.14
-
28
-
-
0037932865
-
Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells
-
Dolma, S., Lessnick, S. L., Hahn, W. C., and Stockwell, B. R. (2003) Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells Cancer Cell 3, 285-296 10.1016/S1535-6108(03)00050-3
-
(2003)
Cancer Cell
, vol.3
, pp. 285-296
-
-
Dolma, S.1
Lessnick, S.L.2
Hahn, W.C.3
Stockwell, B.R.4
-
29
-
-
0033614998
-
Creation of human tumour cells with defined genetic elements
-
Hahn, W. C., Counter, C. M., Lundberg, A. S., Beijersbergen, R. L., Brooks, M. W., and Weinberg, R. A. (1999) Creation of human tumour cells with defined genetic elements Nature 400, 464-468 10.1038/22780
-
(1999)
Nature
, vol.400
, pp. 464-468
-
-
Hahn, W.C.1
Counter, C.M.2
Lundberg, A.S.3
Beijersbergen, R.L.4
Brooks, M.W.5
Weinberg, R.A.6
-
30
-
-
0034680673
-
Chiral Silyl Ketene Acetals from Thioesters: Reaction with Acetals and Peroxyacetals to form 3-Alkoxy- and 3-Peroxyalkanoates
-
Dussault, P. H., Trullinger, T. K., and Cho-Shultz, S. (2000) Chiral Silyl Ketene Acetals from Thioesters: Reaction with Acetals and Peroxyacetals to form 3-Alkoxy- and 3-Peroxyalkanoates Tetrahedron 56, 9213-9220 10.1016/S0040-4020(00)00894-2
-
(2000)
Tetrahedron
, vol.56
, pp. 9213-9220
-
-
Dussault, P.H.1
Trullinger, T.K.2
Cho-Shultz, S.3
-
32
-
-
27744592680
-
Enantiomeric 1,2,4-Trioxanes Display Equivalent in vitro Antimalarial Activity Versus Plasmodium falciparum Malaria Parasites: Implications for the Molecular Mechanism of Action of the Artemisinins
-
O'Neill, P. M., Rawe, S. L., Borstnik, K., Miller, A., Ward, S. A., Bray, P. G., Davies, J., Oh, C. H., and Posner, G. H. (2005) Enantiomeric 1,2,4-Trioxanes Display Equivalent in vitro Antimalarial Activity Versus Plasmodium falciparum Malaria Parasites: Implications for the Molecular Mechanism of Action of the Artemisinins ChemBioChem 6, 2048-2054 10.1002/cbic.200500048
-
(2005)
ChemBioChem
, vol.6
, pp. 2048-2054
-
-
O'Neill, P.M.1
Rawe, S.L.2
Borstnik, K.3
Miller, A.4
Ward, S.A.5
Bray, P.G.6
Davies, J.7
Oh, C.H.8
Posner, G.H.9
-
33
-
-
0027989808
-
Annexin v for Flow Cytometric Detection of Phosphatidylserine Expression on B Cells Undergoing Apoptosis
-
Koopman, G., Reutelingsperger, C. P., Kuijten, G. A., Keehnen, R. M., Pals, S. T., and van Oers, M. H. J. (1994) Annexin V for Flow Cytometric Detection of Phosphatidylserine Expression on B Cells Undergoing Apoptosis Blood 84, 1415-1420
-
(1994)
Blood
, vol.84
, pp. 1415-1420
-
-
Koopman, G.1
Reutelingsperger, C.P.2
Kuijten, G.A.3
Keehnen, R.M.4
Pals, S.T.5
Van Oers, M.H.J.6
-
34
-
-
8444220527
-
Molecular Mechanisms of Caspase Regulation during Apoptosis
-
Riedl, S. J. and Shi, Y. (2004) Molecular Mechanisms of Caspase Regulation during Apoptosis Nat. Rev. Mol. Cell Biol. 5, 897-907 10.1038/nrm1496
-
(2004)
Nat. Rev. Mol. Cell Biol.
, vol.5
, pp. 897-907
-
-
Riedl, S.J.1
Shi, Y.2
-
35
-
-
0015383455
-
Apoptosis: A Basic Biological Phenomenon with Wide-Ranging Implications in Tissue Kinetics
-
Kerr, J. F. R., Wyllie, A. H., and Currie, A. R. (1972) Apoptosis: A Basic Biological Phenomenon with Wide-Ranging Implications in Tissue Kinetics Br. J. Cancer 26, 239-257 10.1038/bjc.1972.33
-
(1972)
Br. J. Cancer
, vol.26
, pp. 239-257
-
-
Kerr, J.F.R.1
Wyllie, A.H.2
Currie, A.R.3
-
36
-
-
22544432640
-
Classification of cell death: Recommendations of the Nomenclature Committee on Cell Death
-
Kroemer, G., El-Deiry, W. S., Golstein, P., Peter, M. E., Vaux, D., Vandenabeele, P., Zhivotovsky, B., Blagosklonny, M. V., Malorni, W., Knight, R. A., Piacentini, M., Nagata, S., and Melino, G. (2005) Classification of cell death: recommendations of the Nomenclature Committee on Cell Death Cell Death Differ. 12, 1463-1467 10.1038/sj.cdd.4401724
-
(2005)
Cell Death Differ.
, vol.12
, pp. 1463-1467
-
-
Kroemer, G.1
El-Deiry, W.S.2
Golstein, P.3
Peter, M.E.4
Vaux, D.5
Vandenabeele, P.6
Zhivotovsky, B.7
Blagosklonny, M.V.8
Malorni, W.9
Knight, R.A.10
Piacentini, M.11
Nagata, S.12
Melino, G.13
-
37
-
-
34250753161
-
Cell death modalities: Classification and pathophysiological implications
-
Galluzzi, L., Maiuri, M. C., Vitale, I., Zischka, H., Castedo, M., Zitvogel, L., and Kroemer, G. (2007) Cell death modalities: classification and pathophysiological implications Cell Death Differ. 14, 1237-1243 10.1038/sj.cdd.4402148
-
(2007)
Cell Death Differ.
, vol.14
, pp. 1237-1243
-
-
Galluzzi, L.1
Maiuri, M.C.2
Vitale, I.3
Zischka, H.4
Castedo, M.5
Zitvogel, L.6
Kroemer, G.7
-
38
-
-
0015918166
-
Selenium: Biochemical Role as a Component of Glutathione Peroxidase
-
Rotruck, J. T., Pope, A. L., Ganther, H. E., Swanson, A. B., Hafeman, D. G., and Hoekstra, W. G. (1973) Selenium: Biochemical Role as a Component of Glutathione Peroxidase Science 179, 588-590 10.1126/science.179.4073.588
-
(1973)
Science
, vol.179
, pp. 588-590
-
-
Rotruck, J.T.1
Pope, A.L.2
Ganther, H.E.3
Swanson, A.B.4
Hafeman, D.G.5
Hoekstra, W.G.6
-
40
-
-
50049133588
-
Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death
-
Seiler, A., Schneider, M., Förster, H., Roth, S., Wirth, E. K., Culmsee, C., Plesnila, N., Kremmer, E., Rådmark, O., Wurst, W., Bornkamm, G. W., Schweizer, U., and Conrad, M. (2008) Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death Cell Metab. 8, 237-248 10.1016/j.cmet.2008.07.005
-
(2008)
Cell Metab.
, vol.8
, pp. 237-248
-
-
Seiler, A.1
Schneider, M.2
Förster, H.3
Roth, S.4
Wirth, E.K.5
Culmsee, C.6
Plesnila, N.7
Kremmer, E.8
Rådmark, O.9
Wurst, W.10
Bornkamm, G.W.11
Schweizer, U.12
Conrad, M.13
-
41
-
-
84925286831
-
Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
-
Friedmann Angeli, J. P., Schneider, M., Proneth, B., Tyurina, Y. Y., Tyurin, V. A., Hammond, V. J., Herbach, N., Aichler, M., Walch, A., Eggenhofer, E., Basavarajappa, D., Rådmark, O., Kobayashi, S., Seibt, T., Beck, H., Neff, F., Esposito, I., Wanke, R., Förster, H., Yefremova, O., Heinrichmeyer, M., Bornkamm, G. W., Geissler, E. K., Thomas, S. B., Stockwell, B. R., O'Donnell, V. B., Kagan, V. E., Schick, J. A., and Conrad, M. (2014) Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice Nat. Cell Biol. 16, 1180-1191 10.1038/ncb3064
-
(2014)
Nat. Cell Biol.
, vol.16
, pp. 1180-1191
-
-
Friedmann Angeli, J.P.1
Schneider, M.2
Proneth, B.3
Tyurina, Y.Y.4
Tyurin, V.A.5
Hammond, V.J.6
Herbach, N.7
Aichler, M.8
Walch, A.9
Eggenhofer, E.10
Basavarajappa, D.11
Rådmark, O.12
Kobayashi, S.13
Seibt, T.14
Beck, H.15
Neff, F.16
Esposito, I.17
Wanke, R.18
Förster, H.19
Yefremova, O.20
Heinrichmeyer, M.21
Bornkamm, G.W.22
Geissler, E.K.23
Thomas, S.B.24
Stockwell, B.R.25
O'Donnell, V.B.26
Kagan, V.E.27
Schick, J.A.28
Conrad, M.29
more..
-
42
-
-
0037101881
-
C11-BODIPY 581/591, an Oxidation-Sensitive Fluorescent Lipid Peroxidation Probe:(micro) Spectroscopic Characterization and Validation of Methodology
-
Drummen, G. P., van Liebergen, L. C., Op den Kamp, J. A., and Post, J. A. (2002) C11-BODIPY 581/591, an Oxidation-Sensitive Fluorescent Lipid Peroxidation Probe:(micro) Spectroscopic Characterization and Validation of Methodology Free Radical Biol. Med. 33, 473-490 10.1016/S0891-5849(02)00848-1
-
(2002)
Free Radical Biol. Med.
, vol.33
, pp. 473-490
-
-
Drummen, G.P.1
Van Liebergen, L.C.2
Op Den Kamp, J.A.3
Post, J.A.4
-
43
-
-
84897059782
-
Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models
-
Skouta, R., Dixon, S. J., Wang, J., Dunn, D. E., Orman, M., Shimada, K., Rosenberg, P. A., Lo, D. C., Weinberg, J. M., Linkermann, A., and Stockwell, B. R. (2014) Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models J. Am. Chem. Soc. 136, 4551-4556 10.1021/ja411006a
-
(2014)
J. Am. Chem. Soc.
, vol.136
, pp. 4551-4556
-
-
Skouta, R.1
Dixon, S.J.2
Wang, J.3
Dunn, D.E.4
Orman, M.5
Shimada, K.6
Rosenberg, P.A.7
Lo, D.C.8
Weinberg, J.M.9
Linkermann, A.10
Stockwell, B.R.11
-
44
-
-
2342587416
-
Prediction of Survival in Diffuse Large-B-Cell Lymphoma Based on the Expression of Six Genes
-
Lossos, I. S., Czerwinski, D. K., Alizadeh, A. A., Wechser, M. A., Tibshirani, R., Botstein, D., and Levy, R. (2004) Prediction of Survival in Diffuse Large-B-Cell Lymphoma Based on the Expression of Six Genes N. Engl. J. Med. 350, 1828-1837 10.1056/NEJMoa032520
-
(2004)
N. Engl. J. Med.
, vol.350
, pp. 1828-1837
-
-
Lossos, I.S.1
Czerwinski, D.K.2
Alizadeh, A.A.3
Wechser, M.A.4
Tibshirani, R.5
Botstein, D.6
Levy, R.7
-
45
-
-
84887098542
-
Bcl2 is an independent prognostic marker of triple negative breast cancer (TNBC) and predicts response to anthracycline combination (ATC) chemotherapy (CT) in adjuvant and neoadjuvant settings
-
Abdel-Fatah, T. M. A., Perry, C., Dickinson, P., Ball, G., Moseley, P., Madhusudan, S., Ellis, I. O., and Chan, S. Y. T. (2013) Bcl2 is an independent prognostic marker of triple negative breast cancer (TNBC) and predicts response to anthracycline combination (ATC) chemotherapy (CT) in adjuvant and neoadjuvant settings Ann. Oncol. 24, 2801-2807 10.1093/annonc/mdt277
-
(2013)
Ann. Oncol.
, vol.24
, pp. 2801-2807
-
-
Abdel-Fatah, T.M.A.1
Perry, C.2
Dickinson, P.3
Ball, G.4
Moseley, P.5
Madhusudan, S.6
Ellis, I.O.7
Chan, S.Y.T.8
-
46
-
-
20444486559
-
An inhibitor of Bcl-2 family proteins induces regression of solid tumours
-
Oltersdorf, T., Elmore, S. W., Shoemaker, A. R., Armstrong, R. C., Augeri, D. J., Belli, B. A., Bruncko, M., Deckwerth, T. L., Dinges, J., Hajduk, P. J., Joseph, M. K., Kitada, S., Korsmeyer, S. J., Kunzer, A. R., Letai, A., Li, C., Mitten, M. J., Nettesheim, D. G., Ng, S., Nimmer, P. M., O'Connor, J. M., Oleksijew, A., Petros, A. M., Reed, J. C., Shen, W., Tahir, S. K., Thompson, C. B., Tomaselli, K. J., Wang, B., Wendt, M. D., Zhang, H., Fesik, S. W., and Rosenberg, S. H. (2005) An inhibitor of Bcl-2 family proteins induces regression of solid tumours Nature 435, 677-681 10.1038/nature03579
-
(2005)
Nature
, vol.435
, pp. 677-681
-
-
Oltersdorf, T.1
Elmore, S.W.2
Shoemaker, A.R.3
Armstrong, R.C.4
Augeri, D.J.5
Belli, B.A.6
Bruncko, M.7
Deckwerth, T.L.8
Dinges, J.9
Hajduk, P.J.10
Joseph, M.K.11
Kitada, S.12
Korsmeyer, S.J.13
Kunzer, A.R.14
Letai, A.15
Li, C.16
Mitten, M.J.17
Nettesheim, D.G.18
Ng, S.19
Nimmer, P.M.20
O'Connor, J.M.21
Oleksijew, A.22
Petros, A.M.23
Reed, J.C.24
Shen, W.25
Tahir, S.K.26
Thompson, C.B.27
Tomaselli, K.J.28
Wang, B.29
Wendt, M.D.30
Zhang, H.31
Fesik, S.W.32
Rosenberg, S.H.33
more..
-
47
-
-
84873540049
-
ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets
-
Souers, A. J., Leverson, J. D., Boghaert, E. R., Ackler, S. L., Catron, N. D., Chen, J., Dayton, B. D., Ding, H., Enschede, S. H., Fairbrother, W. J., Huang, D. C. S., Hymowitz, S. G., Jin, S., Khaw, S. L., Kovar, P. J., Lam, L. T., Lee, J., Maecker, H. L., Marsh, K. C., Mason, K. D., Mitten, M. J., Nimmer, P. M., Oleksijew, A., Park, C. H., Park, C.-M., Phillips, D. C., Roberts, A. W., Sampath, D., Seymour, J. F., Smith, M. L., Sullivan, G. M., Tahir, S. K., Tse, C., Wendt, M. D., Xiao, Y., Xue, J. C., Zhang, H., Humerickhouse, R. A., Rosenberg, S. H., and Elmore, S. W. (2013) ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets Nat. Med. 19, 202-208 10.1038/nm.3048
-
(2013)
Nat. Med.
, vol.19
, pp. 202-208
-
-
Souers, A.J.1
Leverson, J.D.2
Boghaert, E.R.3
Ackler, S.L.4
Catron, N.D.5
Chen, J.6
Dayton, B.D.7
Ding, H.8
Enschede, S.H.9
Fairbrother, W.J.10
Huang, D.C.S.11
Hymowitz, S.G.12
Jin, S.13
Khaw, S.L.14
Kovar, P.J.15
Lam, L.T.16
Lee, J.17
Maecker, H.L.18
Marsh, K.C.19
Mason, K.D.20
Mitten, M.J.21
Nimmer, P.M.22
Oleksijew, A.23
Park, C.H.24
Park, C.-M.25
Phillips, D.C.26
Roberts, A.W.27
Sampath, D.28
Seymour, J.F.29
Smith, M.L.30
Sullivan, G.M.31
Tahir, S.K.32
Tse, C.33
Wendt, M.D.34
Xiao, Y.35
Xue, J.C.36
Zhang, H.37
Humerickhouse, R.A.38
Rosenberg, S.H.39
Elmore, S.W.40
more..
-
48
-
-
33750628289
-
Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia
-
Konopleva, M., Contractor, R., Tsao, T., Samudio, I., Ruvolo, P. P., Kitada, S., Deng, X., Zhai, D., Shi, Y.-X., Sneed, T., Verhaegen, M., Soengas, M., Ruvolo, V. R., McQueen, T., Schober, W. D., Watt, J. C., Jiffar, T., Ling, X., Marini, F. C., Harris, D., Dietrich, M., Estrov, Z., McCubrey, J., May, W. S., Reed, J. C., and Andreeff, M. (2006) Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia Cancer Cell 10, 375-388 10.1016/j.ccr.2006.10.006
-
(2006)
Cancer Cell
, vol.10
, pp. 375-388
-
-
Konopleva, M.1
Contractor, R.2
Tsao, T.3
Samudio, I.4
Ruvolo, P.P.5
Kitada, S.6
Deng, X.7
Zhai, D.8
Shi, Y.-X.9
Sneed, T.10
Verhaegen, M.11
Soengas, M.12
Ruvolo, V.R.13
McQueen, T.14
Schober, W.D.15
Watt, J.C.16
Jiffar, T.17
Ling, X.18
Marini, F.C.19
Harris, D.20
Dietrich, M.21
Estrov, Z.22
McCubrey, J.23
May, W.S.24
Reed, J.C.25
Andreeff, M.26
more..
-
49
-
-
0027451668
-
P53-Dependent Apoptosis Modulates the Cytotoxicity of Anticancer Agents
-
Lowe, S. W., Ruley, H. E., Jacks, T., and Housman, D. E. (1993) p53-Dependent Apoptosis Modulates the Cytotoxicity of Anticancer Agents Cell 74, 957-967 10.1016/0092-8674(93)90719-7
-
(1993)
Cell
, vol.74
, pp. 957-967
-
-
Lowe, S.W.1
Ruley, H.E.2
Jacks, T.3
Housman, D.E.4
-
50
-
-
0031035181
-
An Information-Intensive Approach to the Molecular Pharmacology of Cancer
-
Weinstein, J. N., Myers, T. G., O'Connor, P. M., Friend, S. H., Fornace, A. J., Kohn, K. W., Fojo, T., Bates, S. E., Rubinstein, L. V., Anderson, N. L., Buolamwini, J. K., van Osdol, W. W., Monks, A. P., Scudiero, D. A., Sausville, E. A., Zaharevitz, D. W., Bunow, B., Viswanadhan, V. N., Johnson, G. S., Wittes, R. E., and Paull, K. D. (1997) An Information-Intensive Approach to the Molecular Pharmacology of Cancer Science 275, 343-349 10.1126/science.275.5298.343
-
(1997)
Science
, vol.275
, pp. 343-349
-
-
Weinstein, J.N.1
Myers, T.G.2
O'Connor, P.M.3
Friend, S.H.4
Fornace, A.J.5
Kohn, K.W.6
Fojo, T.7
Bates, S.E.8
Rubinstein, L.V.9
Anderson, N.L.10
Buolamwini, J.K.11
Van Osdol, W.W.12
Monks, A.P.13
Scudiero, D.A.14
Sausville, E.A.15
Zaharevitz, D.W.16
Bunow, B.17
Viswanadhan, V.N.18
Johnson, G.S.19
Wittes, R.E.20
Paull, K.D.21
more..
-
51
-
-
0025894713
-
P53 Mutations in Human Cancers
-
Hollstein, M., Sidransky, D., Vogelstein, B., and Harris, C. (1991) p53 Mutations in Human Cancers Science 253, 49-53 10.1126/science.1905840
-
(1991)
Science
, vol.253
, pp. 49-53
-
-
Hollstein, M.1
Sidransky, D.2
Vogelstein, B.3
Harris, C.4
-
52
-
-
45349097133
-
Analysis of p53 mutation status in human cancer cell lines: A paradigm for cell line cross-contamination
-
Berglind, H., Pawitan, Y., Kato, S., Ishioka, C., and Soussi, T. (2008) Analysis of p53 mutation status in human cancer cell lines: a paradigm for cell line cross-contamination Cancer Biol. Ther. 7, 699-708 10.4161/cbt.7.5.5712
-
(2008)
Cancer Biol. Ther.
, vol.7
, pp. 699-708
-
-
Berglind, H.1
Pawitan, Y.2
Kato, S.3
Ishioka, C.4
Soussi, T.5
-
53
-
-
77955607931
-
Ferroportin and Iron Regulation in Breast Cancer Progression and Prognosis
-
Pinnix, Z. K., Miller, L. D., Wang, W., D'Agostino, R., Kute, T., Willingham, M. C., Hatcher, H., Tesfay, L., Sui, G., Di, X., Torti, S. V., and Torti, F. M. (2010) Ferroportin and Iron Regulation in Breast Cancer Progression and Prognosis Sci. Transl. Med. 2, 43ra56 10.1126/scitranslmed.3001127
-
(2010)
Sci. Transl. Med.
, vol.2
, pp. 43ra56
-
-
Pinnix, Z.K.1
Miller, L.D.2
Wang, W.3
D'Agostino, R.4
Kute, T.5
Willingham, M.C.6
Hatcher, H.7
Tesfay, L.8
Sui, G.9
Di, X.10
Torti, S.V.11
Torti, F.M.12
-
54
-
-
40849085503
-
Synthetic Lethal Screening Identifies Compounds Activating Iron-Dependent, Nonapoptotic Cell Death in Oncogenic-RAS-Harboring Cancer Cells
-
Yang, W. S. and Stockwell, B. R. (2008) Synthetic Lethal Screening Identifies Compounds Activating Iron-Dependent, Nonapoptotic Cell Death in Oncogenic-RAS-Harboring Cancer Cells Chem. Biol. 15, 234-245 10.1016/j.chembiol.2008.02.010
-
(2008)
Chem. Biol.
, vol.15
, pp. 234-245
-
-
Yang, W.S.1
Stockwell, B.R.2
-
55
-
-
80054052917
-
Lipoxygenase and Leukotriene Pathways: Biochemistry, Biology, and Roles in Disease
-
Haeggström, J. Z. and Funk, C. D. (2011) Lipoxygenase and Leukotriene Pathways: Biochemistry, Biology, and Roles in Disease Chem. Rev. 111, 5866-5898 10.1021/cr200246d
-
(2011)
Chem. Rev.
, vol.111
, pp. 5866-5898
-
-
Haeggström, J.Z.1
Funk, C.D.2
-
56
-
-
0025358788
-
Arachidonic Acid Cascade and Signal Transduction
-
Shimizu, T. and Wolfe, L. S. (1990) Arachidonic Acid Cascade and Signal Transduction J. Neurochem. 55, 1-15 10.1111/j.1471-4159.1990.tb08813.x
-
(1990)
J. Neurochem.
, vol.55
, pp. 1-15
-
-
Shimizu, T.1
Wolfe, L.S.2
-
57
-
-
35348840292
-
Physiological role of phospholipid hydroperoxide glutathione peroxidase in mammals
-
Conrad, M., Schneider, M., Seiler, A., and Bornkamm, G. W. (2007) Physiological role of phospholipid hydroperoxide glutathione peroxidase in mammals Biol. Chem. 388, 1019-1025 10.1515/BC.2007.130
-
(2007)
Biol. Chem.
, vol.388
, pp. 1019-1025
-
-
Conrad, M.1
Schneider, M.2
Seiler, A.3
Bornkamm, G.W.4
-
58
-
-
84926387317
-
Ferroptosis as a p53-mediated activity during tumour suppression
-
Jiang, L., Kon, N., Li, T., Wang, S.-J., Su, T., Hibshoosh, H., Baer, R., and Gu, W. (2015) Ferroptosis as a p53-mediated activity during tumour suppression Nature 520, 57-62 10.1038/nature14344
-
(2015)
Nature
, vol.520
, pp. 57-62
-
-
Jiang, L.1
Kon, N.2
Li, T.3
Wang, S.-J.4
Su, T.5
Hibshoosh, H.6
Baer, R.7
Gu, W.8
-
59
-
-
84901323900
-
Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis
-
DOI
-
Dixon, S. J., Patel, D. N., Welsch, M., Skouta, R., Lee, E. D., Hayano, M., Thomas, A. G., Gleason, C. E., Tatonetti, N. P., Slusher, B. S., and Stockwell, B. R. (2014) Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis, eLife 3, DOI: 10.7554/eLife.02523.
-
(2014)
ELife
, vol.3
-
-
Dixon, S.J.1
Patel, D.N.2
Welsch, M.3
Skouta, R.4
Lee, E.D.5
Hayano, M.6
Thomas, A.G.7
Gleason, C.E.8
Tatonetti, N.P.9
Slusher, B.S.10
Stockwell, B.R.11
-
60
-
-
84941550824
-
Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells
-
Ooko, E., Saeed, M. E. M., Kadioglu, O., Sarvi, S., Colak, M., Elmasaoudi, K., Janah, R., Greten, H. J., and Efferth, T. (2015) Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells Phytomedicine 22, 1045-1054 10.1016/j.phymed.2015.08.002
-
(2015)
Phytomedicine
, vol.22
, pp. 1045-1054
-
-
Ooko, E.1
Saeed, M.E.M.2
Kadioglu, O.3
Sarvi, S.4
Colak, M.5
Elmasaoudi, K.6
Janah, R.7
Greten, H.J.8
Efferth, T.9
-
61
-
-
84957431913
-
Identification of artesunate as a specific activator of ferroptosis in pancreatic cancer cells
-
Eling, N., Reuter, L., Hazin, J., Hamacher-Brady, A., and Brady, N. R. (2015) Identification of artesunate as a specific activator of ferroptosis in pancreatic cancer cells Oncoscience 2, 517-532 10.18632/oncoscience.160
-
(2015)
Oncoscience
, vol.2
, pp. 517-532
-
-
Eling, N.1
Reuter, L.2
Hazin, J.3
Hamacher-Brady, A.4
Brady, N.R.5
-
62
-
-
79953194472
-
Artesunate Activates Mitochondrial Apoptosis in Breast Cancer Cells via Iron-catalyzed Lysosomal Reactive Oxygen Species Production
-
Hamacher-Brady, A., Stein, H. A., Turschner, S., Toegel, I., Mora, R., Jennewein, N., Efferth, T., Eils, R., and Brady, N. R. (2011) Artesunate Activates Mitochondrial Apoptosis in Breast Cancer Cells via Iron-catalyzed Lysosomal Reactive Oxygen Species Production J. Biol. Chem. 286, 6587-6601 10.1074/jbc.M110.210047
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 6587-6601
-
-
Hamacher-Brady, A.1
Stein, H.A.2
Turschner, S.3
Toegel, I.4
Mora, R.5
Jennewein, N.6
Efferth, T.7
Eils, R.8
Brady, N.R.9
-
63
-
-
84890922670
-
The role of iron and reactive oxygen species in cell death
-
Dixon, S. J. and Stockwell, B. R. (2014) The role of iron and reactive oxygen species in cell death Nat. Chem. Biol. 10, 9-17 10.1038/nchembio.1416
-
(2014)
Nat. Chem. Biol.
, vol.10
, pp. 9-17
-
-
Dixon, S.J.1
Stockwell, B.R.2
-
64
-
-
34248229771
-
Evidence for the Involvement of Carbon-centered Radicals in the Induction of Apoptotic Cell Death by Artemisinin Compounds
-
Mercer, A. E., Maggs, J. L., Sun, X.-M., Cohen, G. M., Chadwick, J., O'Neill, P. M., and Park, B. K. (2007) Evidence for the Involvement of Carbon-centered Radicals in the Induction of Apoptotic Cell Death by Artemisinin Compounds J. Biol. Chem. 282, 9372-9382 10.1074/jbc.M610375200
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 9372-9382
-
-
Mercer, A.E.1
Maggs, J.L.2
Sun, X.-M.3
Cohen, G.M.4
Chadwick, J.5
O'Neill, P.M.6
Park, B.K.7
-
65
-
-
56149102126
-
Dihydroartemisinin induces apoptosis in HL-60 leukemia cells dependent of iron and p38 mitogen-activated protein kinase activation but independent of reactive oxygen species
-
Lu, J.-J., Meng, L.-H., Cai, Y.-J., Chen, Q., Tong, L.-J., Lin, L.-P., and Ding, J. (2008) Dihydroartemisinin induces apoptosis in HL-60 leukemia cells dependent of iron and p38 mitogen-activated protein kinase activation but independent of reactive oxygen species Cancer Biol. Ther. 7, 1017-1023 10.4161/cbt.7.7.6035
-
(2008)
Cancer Biol. Ther.
, vol.7
, pp. 1017-1023
-
-
Lu, J.-J.1
Meng, L.-H.2
Cai, Y.-J.3
Chen, Q.4
Tong, L.-J.5
Lin, L.-P.6
Ding, J.7
-
66
-
-
84885425764
-
Artemisinin induces A549 cell apoptosis dominantly via a reactive oxygen species-mediated amplification activation loop among caspase-9, -8 and -3
-
Gao, W., Xiao, F., Wang, X., and Chen, T. (2013) Artemisinin induces A549 cell apoptosis dominantly via a reactive oxygen species-mediated amplification activation loop among caspase-9, -8 and -3 Apoptosis 18, 1201-1213 10.1007/s10495-013-0857-z
-
(2013)
Apoptosis
, vol.18
, pp. 1201-1213
-
-
Gao, W.1
Xiao, F.2
Wang, X.3
Chen, T.4
-
67
-
-
83355166871
-
Artesunate Induces Oxidative DNA Damage, Sustained DNA Double-Strand Breaks, and the ATM/ATR Damage Response in Cancer Cells
-
Berdelle, N., Nikolova, T., Quiros, S., Efferth, T., and Kaina, B. (2011) Artesunate Induces Oxidative DNA Damage, Sustained DNA Double-Strand Breaks, and the ATM/ATR Damage Response in Cancer Cells Mol. Cancer Ther. 10, 2224-2233 10.1158/1535-7163.MCT-11-0534
-
(2011)
Mol. Cancer Ther.
, vol.10
, pp. 2224-2233
-
-
Berdelle, N.1
Nikolova, T.2
Quiros, S.3
Efferth, T.4
Kaina, B.5
-
68
-
-
77951651771
-
Growth inhibitory effects of dihydroartemisinin on pancreatic cancer cells: Involvement of cell cycle arrest and inactivation of nuclear factor-κB
-
Chen, H., Sun, B., Wang, S., Pan, S., Gao, Y., Bai, X., and Xue, D. (2010) Growth inhibitory effects of dihydroartemisinin on pancreatic cancer cells: involvement of cell cycle arrest and inactivation of nuclear factor-κB J. Cancer Res. Clin. Oncol. 136, 897-903 10.1007/s00432-009-0731-0
-
(2010)
J. Cancer Res. Clin. Oncol.
, vol.136
, pp. 897-903
-
-
Chen, H.1
Sun, B.2
Wang, S.3
Pan, S.4
Gao, Y.5
Bai, X.6
Xue, D.7
-
69
-
-
56249138250
-
Synthesis of spiro-1,2-dioxolanes and their activity against Plasmodium falciparum
-
Martyn, D. C., Ramirez, A. P., Beattie, M. J., Cortese, J. F., Patel, V., Rush, M. A., Woerpel, K. A., and Clardy, J. (2008) Synthesis of spiro-1,2-dioxolanes and their activity against Plasmodium falciparum Bioorg. Med. Chem. Lett. 18, 6521-6524 10.1016/j.bmcl.2008.10.083
-
(2008)
Bioorg. Med. Chem. Lett.
, vol.18
, pp. 6521-6524
-
-
Martyn, D.C.1
Ramirez, A.P.2
Beattie, M.J.3
Cortese, J.F.4
Patel, V.5
Rush, M.A.6
Woerpel, K.A.7
Clardy, J.8
|