Artemisinin induces A549 cell apoptosis dominantly via a reactive oxygen species-mediated amplification activation loop among caspase-9, -8 and -3

Apoptosis

Volumn 18, Issue 10, 2013, Pages 1201-1213

  Gao, Weijie ^a   Xiao, Fenglian ^a   Wang, Xiaoping ^b   Chen, Tongsheng ^a  

^a SOUTH CHINA NORMAL UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF JINAN UNIVERSITY   (China)

Author keywords

A549 cell; Activation loop; Amplification; Apoptosis; Artemisinin; Caspase; ROS

Indexed keywords

APOPTOSIS INDUCING FACTOR; ARTEMISININ; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; PROTEIN BAK; PROTEIN BAX; REACTIVE OXYGEN METABOLITE; RHODAMINE 123; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; SHORT HAIRPIN RNA;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE AMPLIFICATION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LUNG NON SMALL CELL CANCER; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; RNA INTERFERENCE; ULTRAVIOLET IRRADIATION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; APOPTOSIS; ARTEMISININS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CASPASE 3; CASPASE 8; CASPASE 9; CELL LINE, TUMOR; ENZYME ACTIVATION; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; REACTIVE OXYGEN SPECIES;

EID: 84885425764     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-013-0857-z     Document Type: Article

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