-
1
-
-
0038805259
-
The prevalence and etiology of elevated aminotransferase levels in the United States
-
J. M. Clark, F. L. Brancati, and A. M. Diehl, The prevalence and etiology of elevated aminotransferase levels in the United States, The American Journal of Gastroenterology, vol. 98, no. 5, pp. 960-967, 2003.
-
(2003)
The American Journal of Gastroenterology
, vol.98
, Issue.5
, pp. 960-967
-
-
Clark, J.M.1
Brancati, F.L.2
Diehl, A.M.3
-
2
-
-
77649337140
-
Nonalcoholic fatty liver disease: Pathology and pathogenesis
-
D. G. Tiniakos, M. B. Vos, and E. M. Brunt, Nonalcoholic fatty liver disease: pathology and pathogenesis, Annual Review of Pathology: Mechanisms of Disease, vol. 5, pp. 145-171, 2010.
-
(2010)
Annual Review of Pathology: Mechanisms of Disease
, vol.5
, pp. 145-171
-
-
Tiniakos, D.G.1
Vos, M.B.2
Brunt, E.M.3
-
3
-
-
78049522194
-
Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis
-
H. Tilg and A. R. Moschen, Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis, Hepatology, vol. 52, no. 5, pp. 1836-1846, 2010.
-
(2010)
Hepatology
, vol.52
, Issue.5
, pp. 1836-1846
-
-
Tilg, H.1
Moschen, A.R.2
-
4
-
-
84864110034
-
Management of nonalcoholic steatohepatitis: An evidence-based approach
-
S. E. Mahady and J. George, Management of nonalcoholic steatohepatitis: An evidence-based approach, Clinical Liver Disease, vol. 16, no. 3, pp. 631-645, 2012.
-
(2012)
Clinical Liver Disease
, vol.16
, Issue.3
, pp. 631-645
-
-
Mahady, S.E.1
George, J.2
-
5
-
-
0031947715
-
Steatohepatitis: A tale of two Hits
-
C. P. Day and O. F. W. James, Steatohepatitis: A tale of two Hits Gastroenterology, vol. 114, no. 4, pp. 842-845, 1998.
-
(1998)
Gastroenterology
, vol.114
, Issue.4
, pp. 842-845
-
-
Day, C.P.1
James, O.F.W.2
-
6
-
-
0036780582
-
Pathogenesis of steatohepatitis
-
C. P. Day, Pathogenesis of steatohepatitis, Bailliere's Best Practice and Research in Clinical Gastroenterology, vol. 16, no. 5, pp. 663-678, 2002.
-
(2002)
Bailliere's Best Practice and Research in Clinical Gastroenterology
, vol.16
, Issue.5
, pp. 663-678
-
-
Day, C.P.1
-
7
-
-
0035084699
-
Nonalcoholic steatohepatitis: Association of insulin resistance and mitochondrial abnormalities
-
A. J. Sanyal, C. Campbell-Sargent, F. Mirshahi et al., Nonalcoholic steatohepatitis: Association of insulin resistance and mitochondrial abnormalities, Gastroenterology, vol. 120, no. 5, pp. 1183-1192, 2001.
-
(2001)
Gastroenterology
, vol.120
, Issue.5
, pp. 1183-1192
-
-
Sanyal, A.J.1
Campbell-Sargent, C.2
Mirshahi, F.3
-
8
-
-
84865132718
-
Inflammasomes in liver diseases
-
G. Szabo and T. Csak, Inflammasomes in liver diseases, Journal of Hepatology, vol. 57, no. 3, pp. 642-654, 2012.
-
(2012)
Journal of Hepatology
, vol.57
, Issue.3
, pp. 642-654
-
-
Szabo, G.1
Csak, T.2
-
9
-
-
84880162141
-
The NLRP3 inflammasome as a novel player of the intercellular crosstalk in metabolic disorders
-
E. Benetti, F. Chiazza, N. S. A. Patel, and M. Collino, The NLRP3 inflammasome as a novel player of the intercellular crosstalk in metabolic disorders, Mediators of Inflammation, vol. 2013, Article ID 678627, 9 pages, 2013.
-
(2013)
Mediators of Inflammation
, vol.2013
-
-
Benetti, E.1
Chiazza, F.2
Patel, N.S.A.3
Collino, M.4
-
10
-
-
84855989829
-
Inflammasomes in health and disease
-
T. Strowig, J. Henao-Mejia, E. Elinav, and R. Flavell, Inflammasomes in health and disease, Nature, vol. 481, no. 7381, pp. 278-286, 2012.
-
(2012)
Nature
, vol.481
, Issue.7381
, pp. 278-286
-
-
Strowig, T.1
Henao-Mejia, J.2
Elinav, E.3
Flavell, R.4
-
11
-
-
79959573042
-
Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells
-
T. Csak, M. Ganz, J. Pespisa, K. Kodys, A. Dolganiuc, and G. Szabo, Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells, Hepatology, vol. 54, no. 1, pp. 133-144, 2011.
-
(2011)
Hepatology
, vol.54
, Issue.1
, pp. 133-144
-
-
Csak, T.1
Ganz, M.2
Pespisa, J.3
Kodys, K.4
Dolganiuc, A.5
Szabo, G.6
-
12
-
-
84870541988
-
Elovl6 promotes nonalcoholic steatohepatitis
-
T. Matsuzaka, A. Atsumi, R. Matsumori et al., Elovl6 promotes nonalcoholic steatohepatitis, Hepatology, vol. 56, no. 6, pp. 2199-2208, 2012.
-
(2012)
Hepatology
, vol.56
, Issue.6
, pp. 2199-2208
-
-
Matsuzaka, T.1
Atsumi, A.2
Matsumori, R.3
-
13
-
-
84925300463
-
NLRP3 inflammasomeactivation is required for fibrosis development inNAFLD
-
A. Wree, M. D. McGeough, C. A. Peña et al., NLRP3 inflammasomeactivation is required for fibrosis development inNAFLD, Journal of Molecular Medicine, vol. 92, no. 10, pp. 1069-1082, 2014.
-
(2014)
Journal of Molecular Medicine
, vol.92
, Issue.10
, pp. 1069-1082
-
-
Wree, A.1
McGeough, M.D.2
Peña, C.A.3
-
14
-
-
20044387950
-
Deficiency of interleukin-1 receptor antagonist deteriorates fatty liver and cholesterol metabolism in hypercholesterolemic mice
-
K. Isoda, S. Sawada, M. Ayaori et al., Deficiency of interleukin-1 receptor antagonist deteriorates fatty liver and cholesterol metabolism in hypercholesterolemic mice, Journal of Biological Chemistry, vol. 280, no. 8, pp. 7002-7009, 2005.
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.8
, pp. 7002-7009
-
-
Isoda, K.1
Sawada, S.2
Ayaori, M.3
-
15
-
-
72949123737
-
Pan-caspase inhibitor VX-166 reduces fibrosis in an animal model of nonalcoholic steatohepatitis
-
R. P. Witek, W. C. Stone, F. G. Karaca et al., Pan-caspase inhibitor VX-166 reduces fibrosis in an animal model of nonalcoholic steatohepatitis, Hepatology, vol. 50, no. 5, pp. 1421-1430, 2009.
-
(2009)
Hepatology
, vol.50
, Issue.5
, pp. 1421-1430
-
-
Witek, R.P.1
Stone, W.C.2
Karaca, F.G.3
-
16
-
-
77955852465
-
Impact of pan-caspase inhibition in animal models of established steatosis and nonalcoholic steatohepatitis
-
Q. M. Anstee, D. Concas, H. Kudo et al., Impact of pan-caspase inhibition in animal models of established steatosis and nonalcoholic steatohepatitis, Journal of Hepatology, vol. 53, no. 3, pp. 542-550, 2010.
-
(2010)
Journal of Hepatology
, vol.53
, Issue.3
, pp. 542-550
-
-
Anstee, Q.M.1
Concas, D.2
Kudo, H.3
-
17
-
-
77953891627
-
Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1 in mice
-
K. Miura, Y. Kodama, S. Inokuchi et al., Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1 in mice, Gastroenterology, vol. 139, no. 1, pp. 323-334. e7, 2010.
-
(2010)
Gastroenterology
, vol.139
, Issue.1
, pp. 323-334e7
-
-
Miura, K.1
Kodama, Y.2
Inokuchi, S.3
-
18
-
-
80054737370
-
Lack of interleukin-1 or interleukin-1 inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice
-
Y. Kamari, A. Shaish, E. Vax et al., Lack of interleukin-1 or interleukin-1 inhibits transformation of steatosis to steatohepatitis and liver fibrosis in hypercholesterolemic mice, Journal of Hepatology, vol. 55, no. 5, pp. 1086-1094, 2011.
-
(2011)
Journal of Hepatology
, vol.55
, Issue.5
, pp. 1086-1094
-
-
Kamari, Y.1
Shaish, A.2
Vax, E.3
-
19
-
-
80053087484
-
Inflammasome is a central player in the induction of obesity and insulin resistance
-
R. Stienstra, J. A. van Diepen, C. J. Tack et al., Inflammasome is a central player in the induction of obesity and insulin resistance, Proceedings of the National Academy of Sciences of the United States of America, vol. 108, no. 37, pp. 15324-15329, 2011.
-
(2011)
Proceedings of the National Academy of Sciences of the United States of America
, vol.108
, Issue.37
, pp. 15324-15329
-
-
Stienstra, R.1
Van Diepen, J.A.2
Tack, C.J.3
-
20
-
-
79751512463
-
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
-
B. Vandanmagsar, Y.-H. Youm, A. Ravussin et al., The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance, Nature Medicine, vol. 17, no. 2, pp. 179-188, 2011.
-
(2011)
Nature Medicine
, vol.17
, Issue.2
, pp. 179-188
-
-
Vandanmagsar, B.1
Youm, Y.-H.2
Ravussin, A.3
-
21
-
-
84860280502
-
Caspase-1-mediated regulation of fibrogenesis in diet-induced steatohepatitis
-
L. J. Dixon, M. Berk, S. Thapaliya, B. G. Papouchado, and A. E. Feldstein, Caspase-1-mediated regulation of fibrogenesis in diet-induced steatohepatitis, Laboratory Investigation, vol. 92, no. 5, pp. 713-723, 2012.
-
(2012)
Laboratory Investigation
, vol.92
, Issue.5
, pp. 713-723
-
-
Dixon, L.J.1
Berk, M.2
Thapaliya, S.3
Papouchado, B.G.4
Feldstein, A.E.5
-
22
-
-
84857355693
-
Serum interleukin 1 receptor antagonist as an independent marker of nonalcoholic steatohepatitis in humans
-
J. Pihlajamäki, T. Kuulasmaa, D. Kaminska et al., Serum interleukin 1 receptor antagonist as an independent marker of nonalcoholic steatohepatitis in humans, Journal of Hepatology, vol. 56, no. 3, pp. 663-670, 2012.
-
(2012)
Journal of Hepatology
, vol.56
, Issue.3
, pp. 663-670
-
-
Pihlajamäki, J.1
Kuulasmaa, T.2
Kaminska, D.3
-
23
-
-
84873573078
-
Caspase-1 as a central regulator of high fat dietinduced non-alcoholic steatohepatitis
-
L. J. Dixon, C. A. Flask, B. G. Papouchado, A. E. Feldstein, and L. E. Nagy, Caspase-1 as a central regulator of high fat dietinduced non-alcoholic steatohepatitis, PLoS ONE, vol. 8, no. 2, Article ID e56100, 2013.
-
(2013)
PLoS ONE
, vol.8
, Issue.2
-
-
Dixon, L.J.1
Flask, C.A.2
Papouchado, B.G.3
Feldstein, A.E.4
Nagy, L.E.5
-
24
-
-
84922708241
-
The pancaspase inhibitor Emricasan (IDN-6556) decreases liver injury and fibrosis in amurinemodel of non-alcoholic steatohepatitis
-
F. J. Barreyro, S. Holod, P. V. Finocchietto et al., The pancaspase inhibitor Emricasan (IDN-6556) decreases liver injury and fibrosis in amurinemodel of non-alcoholic steatohepatitis, Liver International, vol. 35, no. 3, pp. 953-966, 2015.
-
(2015)
Liver International
, vol.35
, Issue.3
, pp. 953-966
-
-
Barreyro, F.J.1
Holod, S.2
Finocchietto, P.V.3
-
25
-
-
77955690182
-
Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: The central role of nontriglyceride fatty acid metabolites
-
B. A. Neuschwander-Tetri, Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: The central role of nontriglyceride fatty acid metabolites, Hepatology, vol. 52, no. 2, pp. 774-788, 2010.
-
(2010)
Hepatology
, vol.52
, Issue.2
, pp. 774-788
-
-
Neuschwander-Tetri, B.A.1
-
26
-
-
83555176010
-
Lipotoxicity in NASH
-
M. Fuchs and A. J. Sanyal, Lipotoxicity in NASH, Journal of Hepatology, vol. 56, no. 1, pp. 291-293, 2012.
-
(2012)
Journal of Hepatology
, vol.56
, Issue.1
, pp. 291-293
-
-
Fuchs, M.1
Sanyal, A.J.2
-
27
-
-
84900793058
-
Evolving concepts in the pathogenesis ofNASH: Beyond steatosis and inflammation
-
W. Peverill, L. W. Powell, and R. Skoien, Evolving concepts in the pathogenesis ofNASH: beyond steatosis and inflammation, International Journal of Molecular Sciences, vol. 15, no. 5, pp. 8591-8638, 2014.
-
(2014)
International Journal of Molecular Sciences
, vol.15
, Issue.5
, pp. 8591-8638
-
-
Peverill, W.1
Powell, L.W.2
Skoien, R.3
-
28
-
-
84887319657
-
From NAFLD to NASH to cirrhosis-new insights into diseasemechanisms
-
A. Wree, L. Broderick, A. Canbay, H. M. Hoffman, and A. E. Feldstein, From NAFLD to NASH to cirrhosis-new insights into diseasemechanisms, Nature Reviews Gastroenterology and Hepatology, vol. 10, no. 11, pp. 627-636, 2013.
-
(2013)
Nature Reviews Gastroenterology and Hepatology
, vol.10
, Issue.11
, pp. 627-636
-
-
Wree, A.1
Broderick, L.2
Canbay, A.3
Hoffman, H.M.4
Feldstein, A.E.5
-
29
-
-
36349024819
-
A lipidomic analysis of nonalcoholic fatty liver disease
-
P. Puri, R. A. Baillie, M. M. Wiest et al., A lipidomic analysis of nonalcoholic fatty liver disease, Hepatology, vol. 46, no. 4, pp. 1081-1090, 2007.
-
(2007)
Hepatology
, vol.46
, Issue.4
, pp. 1081-1090
-
-
Puri, P.1
Baillie, R.A.2
Wiest, M.M.3
-
30
-
-
2942706241
-
Increase in long-chain polyunsaturated fatty acid n-6/n-3 ratio in relation to hepatic steatosis in patients with non-alcoholic fatty liver disease
-
J. Araya, R. Rodrigo, L. A. Videla et al., Increase in long-chain polyunsaturated fatty acid n-6/n-3 ratio in relation to hepatic steatosis in patients with non-alcoholic fatty liver disease, Clinical Science, vol. 106, no. 6, pp. 635-643, 2004.
-
(2004)
Clinical Science
, vol.106
, Issue.6
, pp. 635-643
-
-
Araya, J.1
Rodrigo, R.2
Videla, L.A.3
-
31
-
-
84920509623
-
Polyunsaturated fatty acid metabolites as novel lipidomic biomarkers for noninvasive diagnosis of nonalcoholic steatohepatitis
-
R. Loomba, O. Quehenberger, A. Armando, and E. A. Dennis, Polyunsaturated fatty acid metabolites as novel lipidomic biomarkers for noninvasive diagnosis of nonalcoholic steatohepatitis, Journal of Lipid Research, vol. 56, no. 1, pp. 185-192, 2015.
-
(2015)
Journal of Lipid Research
, vol.56
, Issue.1
, pp. 185-192
-
-
Loomba, R.1
Quehenberger, O.2
Armando, A.3
Dennis, E.A.4
-
32
-
-
84907457181
-
Reduced dietary omega-6 to omega-3 fatty acid ratio and 12/15-lipoxygenase deficiency are protective against chronic high fat diet-induced steatohepatitis
-
M. Lazic, M. E. Inzaugarat, D. Povero et al., Reduced dietary omega-6 to omega-3 fatty acid ratio and 12/15-lipoxygenase deficiency are protective against chronic high fat diet-induced steatohepatitis, PLoS ONE, vol. 9, no. 9, Article ID e107658, 2014.
-
(2014)
PLoS ONE
, vol.9
, Issue.9
-
-
Lazic, M.1
Inzaugarat, M.E.2
Povero, D.3
-
33
-
-
77952692915
-
Increased fructose consumption is associatedwith fibrosis severity in patientswith nonalcoholic fatty liver disease
-
M. F. Abdelmalek, A. Suzuki, C. Guy et al., Increased fructose consumption is associatedwith fibrosis severity in patientswith nonalcoholic fatty liver disease, Hepatology, vol. 51, no. 6, pp. 1961-1971, 2010.
-
(2010)
Hepatology
, vol.51
, Issue.6
, pp. 1961-1971
-
-
Abdelmalek, M.F.1
Suzuki, A.2
Guy, C.3
-
34
-
-
34848830434
-
Long term nutritional intake and the risk for non-alcoholic fatty liver disease (NAFLD): A population based study
-
S. Zelber-Sagi, D. Nitzan-Kaluski, R. Goldsmith et al., Long term nutritional intake and the risk for non-alcoholic fatty liver disease (NAFLD): A population based study, Journal of Hepatology, vol. 47, no. 5, pp. 711-717, 2007.
-
(2007)
Journal of Hepatology
, vol.47
, Issue.5
, pp. 711-717
-
-
Zelber-Sagi, S.1
Nitzan-Kaluski, D.2
Goldsmith, R.3
-
35
-
-
43049170503
-
Fructose consumption as a risk factor for non-alcoholic fatty liver disease
-
X. Ouyang, P. Cirillo, Y. Sautin et al., Fructose consumption as a risk factor for non-alcoholic fatty liver disease, Journal of Hepatology, vol. 48, no. 6, pp. 993-999, 2008.
-
(2008)
Journal of Hepatology
, vol.48
, Issue.6
, pp. 993-999
-
-
Ouyang, X.1
Cirillo, P.2
Sautin, Y.3
-
36
-
-
84861975560
-
Synergistic interaction of dietary cholesterol and dietary fat in inducing experimental steatohepatitis
-
C. Savard, E. V. Tartaglione, R. Kuver et al., Synergistic interaction of dietary cholesterol and dietary fat in inducing experimental steatohepatitis, Hepatology, vol. 57, no. 1, pp. 81-92, 2013.
-
(2013)
Hepatology
, vol.57
, Issue.1
, pp. 81-92
-
-
Savard, C.1
Tartaglione, E.V.2
Kuver, R.3
-
37
-
-
67651148531
-
Association between dietary nutrient composition and the incidence of cirrhosis or liver cancer in the United States population
-
G. N. Ioannou, O. B. Morrow, M. L. Connole, and S. P. Lee, Association between dietary nutrient composition and the incidence of cirrhosis or liver cancer in the United States population, Hepatology, vol. 50, no. 1, pp. 175-184, 2009.
-
(2009)
Hepatology
, vol.50
, Issue.1
, pp. 175-184
-
-
Ioannou, G.N.1
Morrow, O.B.2
Connole, M.L.3
Lee, S.P.4
-
38
-
-
84921905230
-
Cholesterollowering drugs cause dissolution of cholesterol crystals and disperse Kupffer cell crown-like structures during resolution of NASH
-
G. N. Ioannou, D. M. Van Rooyen, C. Savard et al., Cholesterollowering drugs cause dissolution of cholesterol crystals and disperse Kupffer cell crown-like structures during resolution of NASH, Journal of Lipid Research, vol. 56, no. 2, pp. 277-285, 2015.
-
(2015)
Journal of Lipid Research
, vol.56
, Issue.2
, pp. 277-285
-
-
Ioannou, G.N.1
Van Rooyen, D.M.2
Savard, C.3
-
39
-
-
84876803994
-
Hepatic cholesterol crystals and crown-like structures distinguish NASH from simple steatosis
-
G. N. Ioannou, W. G. Haigh, D. Thorning, and C. Savard, Hepatic cholesterol crystals and crown-like structures distinguish NASH from simple steatosis, Journal of Lipid Research, vol. 54, no. 5, pp. 1326-1334, 2013.
-
(2013)
Journal of Lipid Research
, vol.54
, Issue.5
, pp. 1326-1334
-
-
Ioannou, G.N.1
Haigh, W.G.2
Thorning, D.3
Savard, C.4
-
40
-
-
79957462315
-
Meta-analysis of the influence of I148Mvariant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease
-
S. Sookoian and C. J. Pirola, Meta-analysis of the influence of I148Mvariant of patatin-like phospholipase domain containing 3 gene (PNPLA3) on the susceptibility and histological severity of nonalcoholic fatty liver disease, Hepatology, vol. 53, no. 6, pp. 1883-1894, 2011.
-
(2011)
Hepatology
, vol.53
, Issue.6
, pp. 1883-1894
-
-
Sookoian, S.1
Pirola, C.J.2
-
41
-
-
56749096610
-
Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease
-
S. Romeo, J. Kozlitina, C. Xing et al., Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease, Nature Genetics, vol. 40, no. 12, pp. 1461-1465, 2008.
-
(2008)
Nature Genetics
, vol.40
, Issue.12
, pp. 1461-1465
-
-
Romeo, S.1
Kozlitina, J.2
Xing, C.3
-
42
-
-
84870042853
-
Kuppfer cells trigger nonalcoholic steatohepatitis development in diet-inducedmouse model through tumor necrosis factor production
-
A.-C. Tosello-Trampont, S. G. Landes, V. Nguyen, T. I. Novobrantseva, and Y. S. Hahn, Kuppfer cells trigger nonalcoholic steatohepatitis development in diet-inducedmouse model through tumor necrosis factor production, The Journal of Biological Chemistry, vol. 287, no. 48, pp. 40161-40172, 2012.
-
(2012)
The Journal of Biological Chemistry
, vol.287
, Issue.48
, pp. 40161-40172
-
-
Tosello-Trampont, A.-C.1
Landes, S.G.2
Nguyen, V.3
Novobrantseva, T.I.4
Hahn, Y.S.5
-
43
-
-
84865041500
-
NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease
-
W.-K. Syn, K. M. Agboola, M. Swiderska et al., NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease, Gut, vol. 61, no. 9, pp. 1323-1329, 2012.
-
(2012)
Gut
, vol.61
, Issue.9
, pp. 1323-1329
-
-
Syn, W.-K.1
Agboola, K.M.2
Swiderska, M.3
-
44
-
-
77952730087
-
Accumulation of natural killer T cells in progressive nonalcoholic fatty liver disease
-
W. K. Syn, Y. H. Oo, T. A. Pereira et al., Accumulation of natural killer T cells in progressive nonalcoholic fatty liver disease, Hepatology, vol. 51, no. 6, pp. 1998-2007, 2010.
-
(2010)
Hepatology
, vol.51
, Issue.6
, pp. 1998-2007
-
-
Syn, W.K.1
Oo, Y.H.2
Pereira, T.A.3
-
45
-
-
84896490614
-
The portal inflammatory infiltrate and ductular reaction in human nonalcoholic fatty liver disease
-
V. L. Gadd, R. Skoien, E. E. Powell et al., The portal inflammatory infiltrate and ductular reaction in human nonalcoholic fatty liver disease, Hepatology, vol. 59, no. 4, pp. 1393-1405, 2014.
-
(2014)
Hepatology
, vol.59
, Issue.4
, pp. 1393-1405
-
-
Gadd, V.L.1
Skoien, R.2
Powell, E.E.3
-
46
-
-
84896722464
-
Adaptive immune responses triggered by oxidative stress contribute to hepatic inflammation in NASH
-
S. Sutti, A. Jindal, I. Locatelli et al., Adaptive immune responses triggered by oxidative stress contribute to hepatic inflammation in NASH, Hepatology, vol. 59, no. 3, pp. 886-897, 2014.
-
(2014)
Hepatology
, vol.59
, Issue.3
, pp. 886-897
-
-
Sutti, S.1
Jindal, A.2
Locatelli, I.3
-
47
-
-
84874595985
-
Blockade of B-cellactivating factor signaling enhances hepatic steatosis induced by a high-fat diet and improves insulin sensitivity
-
K. Kawasaki, M. Abe, F. Tada et al., Blockade of B-cellactivating factor signaling enhances hepatic steatosis induced by a high-fat diet and improves insulin sensitivity, Laboratory Investigation, vol. 93, no. 3, pp. 311-321, 2013.
-
(2013)
Laboratory Investigation
, vol.93
, Issue.3
, pp. 311-321
-
-
Kawasaki, K.1
Abe, M.2
Tada, F.3
-
48
-
-
84880425458
-
Toll-like receptors in alcoholic liver disease, non-alcoholic steatohepatitis and carcinogenesis
-
Y. S. Roh and E. Seki, Toll-like receptors in alcoholic liver disease, non-alcoholic steatohepatitis and carcinogenesis, Journal of Gastroenterology and Hepatology, vol. 28, supplement 1, pp. 38-42, 2013.
-
(2013)
Journal of Gastroenterology and Hepatology
, vol.28
, pp. 38-42
-
-
Roh, Y.S.1
Seki, E.2
-
49
-
-
84907984443
-
Immune and inflammatory pathways in NASH
-
M. Ganz and G. Szabo, Immune and inflammatory pathways in NASH, Hepatology International, vol. 7, supplement 2, pp. 771-781, 2013.
-
(2013)
Hepatology International
, vol.7
, pp. 771-781
-
-
Ganz, M.1
Szabo, G.2
-
50
-
-
84873289589
-
Toll-like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice
-
K. Miura, L. Yang, N. van Rooijen, D. A. Brenner, H. Ohnishi, and E. Seki, Toll-like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice, Hepatology, vol. 57, no. 2, pp. 577-589, 2013.
-
(2013)
Hepatology
, vol.57
, Issue.2
, pp. 577-589
-
-
Miura, K.1
Yang, L.2
Van Rooijen, N.3
Brenner, D.A.4
Ohnishi, H.5
Seki, E.6
-
51
-
-
77955492173
-
Toll-like receptor 2-deficient mice are protected frominsulin resistance and beta cell dysfunction induced by a high-fat diet
-
J. A. Ehses, D. T. Meier, S. Wueest et al., Toll-like receptor 2-deficient mice are protected frominsulin resistance and beta cell dysfunction induced by a high-fat diet, Diabetologia, vol. 53, no. 8, pp. 1795-1806, 2010.
-
(2010)
Diabetologia
, vol.53
, Issue.8
, pp. 1795-1806
-
-
Ehses, J.A.1
Meier, D.T.2
Wueest, S.3
-
52
-
-
32044438279
-
Modulation of non-alcoholic steatohepatitis by pattern recognition receptors in mice: The role of toll-like receptors 2 and 4
-
G. Szabo, A. Velayudham, L. Romics Jr., and P. Mandrekar, Modulation of non-alcoholic steatohepatitis by pattern recognition receptors in mice: The role of toll-like receptors 2 and 4, Alcoholism: Clinical and Experimental Research, vol. 29, no. 11, pp. 140s-145s, 2005.
-
(2005)
Alcoholism: Clinical and Experimental Research
, vol.29
, Issue.11
, pp. 140s-145s
-
-
Szabo, G.1
Velayudham, A.2
Romics, L.3
Mandrekar, P.4
-
53
-
-
77952688386
-
Toll-like receptor-2 deficiency enhances non-alcoholic steatohepatitis
-
C. A. Rivera, L. Gaskin, M. Allman et al., Toll-like receptor-2 deficiency enhances non-alcoholic steatohepatitis, BMC Gastroenterology, vol. 10, article 52, 2010.
-
(2010)
BMC Gastroenterology
, vol.10
-
-
Rivera, C.A.1
Gaskin, L.2
Allman, M.3
-
54
-
-
80055043169
-
Nuclear factor high-mobility group box1 mediating the activation of toll-like receptor 4 signaling in hepatocytes in the early stage of nonalcoholic fatty liver disease in mice
-
L. Li, L. Chen, L. Hu et al., Nuclear factor high-mobility group box1 mediating the activation of toll-like receptor 4 signaling in hepatocytes in the early stage of nonalcoholic fatty liver disease in mice, Hepatology, vol. 54, no. 5, pp. 1620-1630, 2011.
-
(2011)
Hepatology
, vol.54
, Issue.5
, pp. 1620-1630
-
-
Li, L.1
Chen, L.2
Hu, L.3
-
55
-
-
34548272744
-
Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of nonalcoholic steatohepatitis
-
C. A. Rivera, P. Adegboyega, N. van Rooijen, A. Tagalicud, M. Allman, and M. Wallace, Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of nonalcoholic steatohepatitis, Journal of Hepatology, vol. 47, no. 4, pp. 571-579, 2007.
-
(2007)
Journal of Hepatology
, vol.47
, Issue.4
, pp. 571-579
-
-
Rivera, C.A.1
Adegboyega, P.2
Van Rooijen, N.3
Tagalicud, A.4
Allman, M.5
Wallace, M.6
-
56
-
-
84861547908
-
Toll-like receptor-4mediates obesity-induced non-alcoholic steatohepatitis through activation of X-box binding protein-1 in mice
-
D. Ye, F. Y. L. Li, K. S. L. Lamet al., Toll-like receptor-4mediates obesity-induced non-alcoholic steatohepatitis through activation of X-box binding protein-1 in mice, Gut, vol. 61, no. 7, pp. 1058-1067, 2012.
-
(2012)
Gut
, vol.61
, Issue.7
, pp. 1058-1067
-
-
Ye, D.1
Li, F.Y.L.2
Lam, K.S.L.3
-
57
-
-
84903893149
-
Toll-like receptor-4 signalling in the progression of non-alcoholic fatty liver disease induced by high-fat and high-fructose diet in mice
-
J. Liu, Z.-J. Zhuang, D.-X. Bian et al., Toll-like receptor-4 signalling in the progression of non-alcoholic fatty liver disease induced by high-fat and high-fructose diet in mice, Clinical and Experimental Pharmacology and Physiology, vol. 41, no. 7, pp. 482-488, 2014.
-
(2014)
Clinical and Experimental Pharmacology and Physiology
, vol.41
, Issue.7
, pp. 482-488
-
-
Liu, J.1
Zhuang, Z.-J.2
Bian, D.-X.3
-
58
-
-
84896992224
-
TLR4 gene polymorphism in patients with nonalcoholic fatty liver disease in comparison to healthy controls
-
S. Kiziltas, P. Ata, Y. Colak et al., TLR4 gene polymorphism in patients with nonalcoholic fatty liver disease in comparison to healthy controls, Metabolic Syndrome and Related Disorders, vol. 12, no. 3, pp. 165-170, 2014.
-
(2014)
Metabolic Syndrome and Related Disorders
, vol.12
, Issue.3
, pp. 165-170
-
-
Kiziltas, S.1
Ata, P.2
Colak, Y.3
-
59
-
-
84908238878
-
Both bone marrow-derived and non-bone marrow-derived cells contribute to AIM2 and NLRP3 inflammasome activation in aMyD88-dependentmanner in dietary steatohepatitis
-
T. Csak, A. Pillai, M. Ganz et al., Both bone marrow-derived and non-bone marrow-derived cells contribute to AIM2 and NLRP3 inflammasome activation in aMyD88-dependentmanner in dietary steatohepatitis, Liver International, vol. 34, no. 9, pp. 1402-1413, 2014.
-
(2014)
Liver International
, vol.34
, Issue.9
, pp. 1402-1413
-
-
Csak, T.1
Pillai, A.2
Ganz, M.3
-
60
-
-
79955598839
-
Gut-liver axis and sensing microbes
-
G. Szabo, S. Bala, J. Petrasek, and A. Gattu, Gut-liver axis and sensing microbes, DigestiveDiseases, vol. 28, no. 6, pp. 737-744, 2010.
-
(2010)
DigestiveDiseases
, vol.28
, Issue.6
, pp. 737-744
-
-
Szabo, G.1
Bala, S.2
Petrasek, J.3
Gattu, A.4
-
61
-
-
84881336923
-
Gut-liver axis and microbiota in NAFLD: Insight pathophysiology for novel therapeutic target
-
L. Miele, G. Marrone, C. Lauritano et al., Gut-liver axis and microbiota in NAFLD: insight pathophysiology for novel therapeutic target, Current Pharmaceutical Design, vol. 19, no. 29, pp. 5314-5324, 2013.
-
(2013)
Current Pharmaceutical Design
, vol.19
, Issue.29
, pp. 5314-5324
-
-
Miele, L.1
Marrone, G.2
Lauritano, C.3
-
62
-
-
79952230506
-
Role of tolllike receptors and their downstream molecules in the development of nonalcoholic fatty liver disease
-
K. Miura, E. Seki, H. Ohnishi, and D. A. Brenner, Role of tolllike receptors and their downstream molecules in the development of nonalcoholic fatty liver disease, Gastroenterology Research and Practice, vol. 2010, Article ID362847, 9 pages, 2010.
-
(2010)
Gastroenterology Research and Practice
, vol.2010
-
-
Miura, K.1
Seki, E.2
Ohnishi, H.3
Brenner, D.A.4
-
63
-
-
47949095562
-
Susceptibility to gut leakiness: A possible mechanism for endotoxaemia in nonalcoholic steatohepatitis
-
A. Farhadi, S. Gundlapalli, M. Shaikh et al., Susceptibility to gut leakiness: A possible mechanism for endotoxaemia in nonalcoholic steatohepatitis, Liver International, vol. 28, no. 7, pp. 1026-1033, 2008.
-
(2008)
Liver International
, vol.28
, Issue.7
, pp. 1026-1033
-
-
Farhadi, A.1
Gundlapalli, S.2
Shaikh, M.3
-
64
-
-
63349101854
-
VSL#3 probiotic treatment attenuates fibrosis without changes in steatohepatitis in a diet-induced nonalcoholic steatohepatitis model in mice
-
A. Velayudham, A. Dolganiuc, M. Ellis et al., VSL#3 probiotic treatment attenuates fibrosis without changes in steatohepatitis in a diet-induced nonalcoholic steatohepatitis model in mice, Hepatology, vol. 49, no. 3, pp. 989-997, 2009.
-
(2009)
Hepatology
, vol.49
, Issue.3
, pp. 989-997
-
-
Velayudham, A.1
Dolganiuc, A.2
Ellis, M.3
-
65
-
-
79959712086
-
Effects of two Lactobacillus strains on lipid metabolism and intestinal microflora in rats fed a high-cholesterol diet
-
N. Xie, Y. Cui, Y.-N. Yin et al., Effects of two Lactobacillus strains on lipid metabolism and intestinal microflora in rats fed a high-cholesterol diet, BMC Complementary and Alternative Medicine, vol. 11, article 53, 2011.
-
(2011)
BMC Complementary and Alternative Medicine
, vol.11
-
-
Xie, N.1
Cui, Y.2
Yin, Y.-N.3
-
66
-
-
84898879701
-
Lack of interleukin-1 in Kupffer cells attenuates liver inflammation and expression of inflammatory cytokines in hypercholesterolaemic mice
-
S. Olteanu, M. Kandel-Kfir, A. Shaish et al., Lack of interleukin-1 in Kupffer cells attenuates liver inflammation and expression of inflammatory cytokines in hypercholesterolaemic mice, Digestive and Liver Disease, vol. 46, no. 5, pp. 433-439, 2014.
-
(2014)
Digestive and Liver Disease
, vol.46
, Issue.5
, pp. 433-439
-
-
Olteanu, S.1
Kandel-Kfir, M.2
Shaish, A.3
-
67
-
-
84879357128
-
Quercetinandallopurinol reduce liver thioredoxin-interacting protein to alleviate inflammation and lipid accumulation in diabetic rats
-
W. Wang, C. Wang, X.-Q. Ding et al., Quercetinandallopurinol reduce liver thioredoxin-interacting protein to alleviate inflammation and lipid accumulation in diabetic rats, British Journal of Pharmacology, vol. 169, no. 6, pp. 1352-1371, 2013.
-
(2013)
British Journal of Pharmacology
, vol.169
, Issue.6
, pp. 1352-1371
-
-
Wang, W.1
Wang, C.2
Ding, X.-Q.3
-
68
-
-
79955038882
-
Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling
-
H. Wen, D. Gris, Y. Lei et al., Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling, Nature Immunology, vol. 12, no. 5, pp. 408-415, 2011.
-
(2011)
Nature Immunology
, vol.12
, Issue.5
, pp. 408-415
-
-
Wen, H.1
Gris, D.2
Lei, Y.3
-
69
-
-
84856957894
-
Inflammasomemediated dysbiosis regulates progression of NAFLD and obesity
-
J. Henao-Mejia, E. Elinav, C. Jin et al., Inflammasomemediated dysbiosis regulates progression of NAFLD and obesity, Nature, vol. 482, no. 7384, pp. 179-185, 2012.
-
(2012)
Nature
, vol.482
, Issue.7384
, pp. 179-185
-
-
Henao-Mejia, J.1
Elinav, E.2
Jin, C.3
-
70
-
-
84856400671
-
A phase 2, randomized, double-blind, placebo-controlled study of GS-9450 in subjects with nonalcoholic steatohepatitis
-
V. Ratziu, M. Y. Sheikh, A. J. Sanyal et al., A phase 2, randomized, double-blind, placebo-controlled study of GS-9450 in subjects with nonalcoholic steatohepatitis, Hepatology, vol. 55, no. 2, pp. 419-428, 2012.
-
(2012)
Hepatology
, vol.55
, Issue.2
, pp. 419-428
-
-
Ratziu, V.1
Sheikh, M.Y.2
Sanyal, A.J.3
|