Reduced dietary omega-6 to omega-3 fatty acid ratio and 12/15-lipoxygenase deficiency are protective against chronic high fat diet-induced steatohepatitis

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Lazic, Milos ^a   Inzaugarat, Maria Eugenia ^b   Povero, Davide ^a   Zhao, Iris C ^c   Chen, Mark ^d   Nalbandian, Madlena ^d   Miller, Yury I ^d   Cherñavsky, Alejandra C ^b   Feldstein, Ariel E ^a   Sears, Dorothy D ^d  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b Hospital de Clínicas José de San Martín   (Argentina)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONATE 12 LIPOXYGENASE; ARACHIDONATE 15 LIPOXYGENASE; ARACHIDONIC ACID; FISH OIL; LINOLEIC ACID; MESSENGER RNA; MONOUNSATURATED FATTY ACID; OMEGA 3 FATTY ACID; OMEGA 6 FATTY ACID; POLYUNSATURATED FATTY ACID; SATURATED FATTY ACID; SOYBEAN OIL; TRIACYLGLYCEROL; 12-15-LIPOXYGENASE; BETA 2 MICROGLOBULIN; PORPHOBILINOGEN DEAMINASE;

ADAPTIVE IMMUNITY; ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME DEFICIENCY; FAT CONTENT; FAT INTAKE; FOOD COMPOSITION; FOOD INTAKE; GENE EXPRESSION; INFLAMMATION; INNATE IMMUNITY; INSULIN RESISTANCE; KNOCKOUT MOUSE; LIPID DIET; LIPID LIVER LEVEL; LIVER PROTECTION; LYMPHOCYTE HOMING; MALE; NONALCOHOLIC FATTY LIVER; NONHUMAN; WILD TYPE; ADVERSE EFFECTS; ANIMAL; BLOOD; C57BL MOUSE; DEFICIENCY; DIET; EATING; FATTY LIVER; GENETICS; LIVER; METABOLISM; OBESITY; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; ARACHIDONATE 12-LIPOXYGENASE; ARACHIDONATE 15-LIPOXYGENASE; ARACHIDONIC ACID; BETA 2-MICROGLOBULIN; DIET; DIET, HIGH-FAT; EATING; FATTY ACIDS, OMEGA-3; FATTY ACIDS, OMEGA-6; FATTY LIVER; GENE EXPRESSION; HYDROXYMETHYLBILANE SYNTHASE; LIVER; MICE, INBRED C57BL; MICE, KNOCKOUT; OBESITY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRIGLYCERIDES;

EID: 84907457181     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0107658     Document Type: Article

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