Caspase-1-mediated regulation of fibrogenesis in diet-induced steatohepatitis

Laboratory Investigation

Volumn 92, Issue 5, 2012, Pages 713-723

  Dixon, Laura J ^a,b   Berk, Michael ^b   Thapaliya, Samjhana ^b   Papouchado, Bettina G ^b   Feldstein, Ariel E ^b,c  

^a CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Caspases; Fibrosis; Inflammasome; Inflammation; Non alcoholic fatty liver disease; Non alcoholic steatohepatitis

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA ACTIN; CASPASE 3; CYSTEINE; GLYCINE; GLYCINE RICH PROTEIN 2; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; DISEASE COURSE; FIBROGENESIS; FRACTIONATION; GENE EXPRESSION; KNOCKOUT GENE; LIVER CELL; LIVER FIBROSIS; LIVER INJURY; MALE; MOUSE; NICK END LABELING; NONALCOHOLIC FATTY LIVER; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; WILD TYPE;

ACTINS; ANIMALS; ANTIGENS, DIFFERENTIATION; CASPASE 1; CASPASE 3; CHOLINE DEFICIENCY; CLODRONIC ACID; COLLAGEN TYPE I; FATTY LIVER; HEPATIC STELLATE CELLS; HEPATOCYTES; INFLAMMATION; INTERLEUKIN-1BETA; KUPFFER CELLS; LIM DOMAIN PROTEINS; LIVER; LIVER CIRRHOSIS; METHIONINE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MUSCLE PROTEINS; NUCLEAR PROTEINS; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84860280502     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2012.45     Document Type: Article

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