Withania somnifera and Its Withanolides Attenuate Oxidative and Inflammatory Responses and Up-Regulate Antioxidant Responses in BV-2 Microglial Cells

NeuroMolecular Medicine

Volumn 18, Issue 3, 2016, Pages 241-252

  Sun, Grace Y ^a,b   Li, Runting ^a,b   Cui, Jiankun ^a,b   Hannink, Mark ^a,b   Gu, Zezong ^a,b   Fritsche, Kevin L ^b   Lubahn, Dennis B ^a,b   Simonyi, Agnes ^a,b  

^a University of Missouri   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

Author keywords

Ashwagandha; HO 1; LPS; Microglia; NO; Nrf2; Withaferin A; Withanolide A

Indexed keywords

HEME OXYGENASE 1; NITRIC OXIDE; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; WITHAFERIN A; WITHANIA SOMNIFERA EXTRACT; WITHANOLIDE; WITHANOLIDE A; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOLOGIC FACTOR; NEUROPROTECTIVE AGENT; NFE2L2 PROTEIN, MOUSE; PLANT EXTRACT;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG STRUCTURE; GENE EXPRESSION; IMMUNE RESPONSE; IMMUNOMODULATION; MICROGLIA; OXIDATIVE STRESS; PHYTOCHEMISTRY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; CELL LINE; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; MOUSE; WITHANIA;

ANIMALS; CELL LINE; GENE EXPRESSION REGULATION; IMMUNOLOGIC FACTORS; MICE; MICROGLIA; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; NF-KAPPA B; OXIDATIVE STRESS; PLANT EXTRACTS; WITHANIA; WITHANOLIDES;

EID: 84969799067     PISSN: 15351084     EISSN: 15591174     Source Type: Journal    
DOI: 10.1007/s12017-016-8411-0     Document Type: Article

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