-
1
-
-
23144438005
-
African herbal medicines in the treatment of HIV: Hypoxis and Sutherlandia. An overview of evidence and pharmacology
-
Mills E, Cooper C, Seely D, Kanfer I (2005) African herbal medicines in the treatment of HIV: Hypoxis and Sutherlandia. An overview of evidence and pharmacology. Nutr J 4: 19.
-
(2005)
Nutr J
, vol.4
, pp. 19
-
-
Mills, E.1
Cooper, C.2
Seely, D.3
Kanfer, I.4
-
2
-
-
11244261387
-
The effect of Sutherlandia frutescens on steroidogenesis: Confirming indigenous wisdom
-
DOI 10.1081/ERC-200044020
-
Prevoo D, Smith C, Swart P, Swart AC (2004) The effect of Sutherlandia frutescens on steroidogenesis: confirming indigenous wisdom. Endocr Res 30: 745-751. (Pubitemid 40070162)
-
(2004)
Endocrine Research
, vol.30
, Issue.4
, pp. 745-751
-
-
Prevoo, D.1
Smith, C.2
Swart, P.3
Swart, A.C.4
-
3
-
-
53449096059
-
A review of the taxonomy, ethnobotany, chemistry and pharmacology of Sutherlandia frutescens (Fabaceae)
-
van Wyk BE, Albrecht C (2008) A review of the taxonomy, ethnobotany, chemistry and pharmacology of Sutherlandia frutescens (Fabaceae). J Ethnopharmacol 119: 620-629.
-
(2008)
J Ethnopharmacol
, vol.119
, pp. 620-629
-
-
Van Wyk, B.E.1
Albrecht, C.2
-
4
-
-
4544289650
-
The antioxidant potential of Sutherlandia frutescens
-
DOI 10.1016/j.jep.2004.05.024, PII S0378874104003058
-
Fernandes AC, Cromarty AD, Albrecht C, van Rensburg CE (2004) The antioxidant potential of Sutherlandia frutescens. J Ethnopharmacol 95: 1-5. (Pubitemid 39221403)
-
(2004)
Journal of Ethnopharmacology
, vol.95
, Issue.1
, pp. 1-5
-
-
Fernandes, A.C.1
Cromarty, A.D.2
Albrecht, C.3
Jansen, V.R.C.E.4
-
5
-
-
27644521173
-
Antibacterial and antioxidant activity of Sutherlandia frutescens (Fabaceae), a reputed anti-HIV/AIDS phytomedicine
-
DOI 10.1002/ptr.1719
-
Katerere DR, Eloff JN (2005) Antibacterial and antioxidant activity of Sutherlandia frutescens (Fabaceae), a reputed anti-HIV/AIDS phytomedicine. Phytother Res 19: 779-781. (Pubitemid 41571427)
-
(2005)
Phytotherapy Research
, vol.19
, Issue.9
, pp. 779-781
-
-
Katerere, D.R.1
Eloff, J.N.2
-
6
-
-
11444262229
-
Inhibitory effects of the extracts of Sutherlandia frutescens (L.) R. Br. and Harpagophytum procumbens DC. on phorbol ester-induced COX-2 expression in mouse skin: AP-1 and CREB as potential upstream targets
-
DOI 10.1016/j.canlet.2004.07.029, PII S0304383504005804
-
Kundu JK, Mossanda KS, Na HK, Surh YJ (2005) Inhibitory effects of the extracts of Sutherlandia frutescens (L.) R. Br. and Harpagophytum procumbens DC. on phorbol ester-induced COX-2 expression in mouse skin: AP-1 and CREB as potential upstream targets. Cancer Lett 218: 21-31. (Pubitemid 40082698)
-
(2005)
Cancer Letters
, vol.218
, Issue.1
, pp. 21-31
-
-
Kundu, J.K.1
Mossanda, K.S.2
Na, H.-K.3
Surh, Y.-J.4
-
7
-
-
16444375648
-
Inhibition of phorbol ester-induced COX-2 expression by some edible African plants
-
Na HK, Mossanda KS, Lee JY, Surh YJ (2004) Inhibition of phorbol ester-induced COX-2 expression by some edible African plants. Biofactors 21: 149-153. (Pubitemid 40921844)
-
(2004)
BioFactors
, vol.21
, Issue.1-4
, pp. 149-153
-
-
Na, H.-K.1
Mossanda, K.S.2
Lee, J.-Y.3
Surh, Y.-J.4
-
8
-
-
4043057916
-
Analgesic, antiinflammatory and hypoglycemic effects of Sutherlandia frutescens R. BR. (variety Incana E. MEY.) [Fabaceae] shoot aqueous extract
-
Ojewole JA (2004) Analgesic, antiinflammatory and hypoglycemic effects of Sutherlandia frutescens R. BR. (variety Incana E. MEY.) [Fabaceae] shoot aqueous extract. Methods Find Exp Clin Pharmacol 26: 409-416.
-
(2004)
Methods Find Exp Clin Pharmacol
, vol.26
, pp. 409-416
-
-
Ojewole, J.A.1
-
9
-
-
37349098306
-
Anticonvulsant property of Sutherlandia frutescens R. BR. (variety Incana E. MEY.) [Fabaceae] shoot aqueous extract
-
Ojewole JA (2008) Anticonvulsant property of Sutherlandia frutescens R. BR. (variety Incana E. MEY.) [Fabaceae] shoot aqueous extract. Brain Res Bull 75: 126-132.
-
(2008)
Brain Res Bull
, vol.75
, pp. 126-132
-
-
Ojewole, J.A.1
-
10
-
-
77950363010
-
Mechanisms underlying inflammation in neurodegeneration
-
Glass CK, Saijo K, Winner B, Marchetto MC, Gage FH (2010) Mechanisms underlying inflammation in neurodegeneration. Cell 140: 918-934.
-
(2010)
Cell
, vol.140
, pp. 918-934
-
-
Glass, C.K.1
Saijo, K.2
Winner, B.3
Marchetto, M.C.4
Gage, F.H.5
-
12
-
-
84872168596
-
Microglia: Scapegoat, saboteur, or something else?
-
Aguzzi A, Barres BA, Bennett ML (2013) Microglia: scapegoat, saboteur, or something else? Science 339: 156-161.
-
(2013)
Science
, vol.339
, pp. 156-161
-
-
Aguzzi, A.1
Barres, B.A.2
Bennett, M.L.3
-
13
-
-
36749005178
-
Mechanisms of inflammatory neurodegeneration: INOS and NADPH oxidase
-
Brown GC (2007) Mechanisms of inflammatory neurodegeneration: iNOS and NADPH oxidase. Biochem Soc Trans 35: 1119-1121.
-
(2007)
Biochem Soc Trans
, vol.35
, pp. 1119-1121
-
-
Brown, G.C.1
-
14
-
-
33746354022
-
Tumor necrosis factor-alpha induces neurotoxicity via glutamate release from hemichannels of activated microglia in an autocrine manner
-
DOI 10.1074/jbc.M600504200
-
Takeuchi H, Jin S, Wang J, Zhang G, Kawanokuchi J, et al. (2006) Tumor necrosis factor-alpha induces neurotoxicity via glutamate release from hemichannels of activated microglia in an autocrine manner. J Biol Chem 281: 21362-21368. (Pubitemid 44115475)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.30
, pp. 21362-21368
-
-
Takeuchi, H.1
Jin, S.2
Wang, J.3
Zhang, G.4
Kawanokuchi, J.5
Kuno, R.6
Sonobe, Y.7
Mizuno, T.8
Suzumura, A.9
-
15
-
-
33748750998
-
Dual effects of antioxidants in neurodegeneration: Direct neuroprotection against oxidative stress and indirect protection via suppression of glia-mediated inflammation
-
Wang JY, Wen LL, Huang YN, Chen YT, Ku MC (2006) Dual effects of antioxidants in neurodegeneration: direct neuroprotection against oxidative stress and indirect protection via suppression of glia-mediated inflammation. Curr Pharm Des 12: 3521-3533.
-
(2006)
Curr Pharm des
, vol.12
, pp. 3521-3533
-
-
Wang, J.Y.1
Wen, L.L.2
Huang, Y.N.3
Chen, Y.T.4
Ku, M.C.5
-
16
-
-
77955087547
-
Recent developments in understanding oxidative mechanisms and contributions of glial cell activation, mitochondrial dysfunction, and lipids and signaling pathways to neurodegenerative diseases. Preface
-
Sun GY, Wood WG (2010) Recent developments in understanding oxidative mechanisms and contributions of glial cell activation, mitochondrial dysfunction, and lipids and signaling pathways to neurodegenerative diseases. Preface. Mol Neurobiol 41: 53-54.
-
(2010)
Mol Neurobiol
, vol.41
, pp. 53-54
-
-
Sun, G.Y.1
Wood, W.G.2
-
17
-
-
67650034374
-
Involvement of oxidative pathways in cytokine-induced secretory phospholipase A2-IIA in astrocytes
-
Jensen MD, Sheng W, Simonyi A, Johnson GS, Sun AY, et al. (2009) Involvement of oxidative pathways in cytokine-induced secretory phospholipase A2-IIA in astrocytes. Neurochem Int 55: 362-368.
-
(2009)
Neurochem Int
, vol.55
, pp. 362-368
-
-
Jensen, M.D.1
Sheng, W.2
Simonyi, A.3
Johnson, G.S.4
Sun, A.Y.5
-
18
-
-
21744454982
-
Distinct signaling pathways for induction of type II NOS by IFNgamma and LPS in BV-2 microglial cells
-
DOI 10.1016/j.neuint.2005.03.007, PII S0197018605001129
-
Shen S, Yu S, Binek J, Chalimoniuk M, Zhang X, et al. (2005) Distinct signaling pathways for induction of type II NOS by IFNgamma and LPS in BV-2 microglial cells. Neurochem Int 47: 298-307. (Pubitemid 40943472)
-
(2005)
Neurochemistry International
, vol.47
, Issue.4
, pp. 298-307
-
-
Shen, S.1
Yu, S.2
Binek, J.3
Chalimoniuk, M.4
Zhang, X.5
Lo, S.-C.6
Hannink, M.7
Wu, J.8
Fritsche, K.9
Donato, R.10
Sun, G.Y.11
-
19
-
-
80053175796
-
Pro-inflammatory cytokines and lipopolysaccharide induce changes in cell morphology, and upregulation of ERK1/2, iNOS and sPLA(2)-IIA expression in astrocytes and microglia
-
Sheng W, Zong Y, Mohammad A, Ajit D, Cui J, et al. (2011) Pro-inflammatory cytokines and lipopolysaccharide induce changes in cell morphology, and upregulation of ERK1/2, iNOS and sPLA(2)-IIA expression in astrocytes and microglia. J Neuroinflammation 8: 121.
-
(2011)
J Neuroinflammation
, vol.8
, pp. 121
-
-
Sheng, W.1
Zong, Y.2
Mohammad, A.3
Ajit, D.4
Cui, J.5
-
20
-
-
33845768784
-
Microglia-mediated neurotoxicity: Uncovering the molecular mechanisms
-
DOI 10.1038/nrn2038, PII NRN2038
-
Block ML, Zecca L, Hong JS (2007) Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nat Rev Neurosci 8: 57-69. (Pubitemid 46011999)
-
(2007)
Nature Reviews Neuroscience
, vol.8
, Issue.1
, pp. 57-69
-
-
Block, M.L.1
Zecca, L.2
Hong, J.-S.3
-
21
-
-
77956012154
-
Nitric oxide and neuronal death
-
Brown GC (2010) Nitric oxide and neuronal death. Nitric Oxide 23: 153-165.
-
(2010)
Nitric Oxide
, vol.23
, pp. 153-165
-
-
Brown, G.C.1
-
22
-
-
77955085839
-
Inflammatory neurodegeneration and mechanisms of microglial killing of neurons
-
Brown GC, Neher JJ (2010) Inflammatory neurodegeneration and mechanisms of microglial killing of neurons. Mol Neurobiol 41: 242-247.
-
(2010)
Mol Neurobiol
, vol.41
, pp. 242-247
-
-
Brown, G.C.1
Neher, J.J.2
-
24
-
-
45249097300
-
2 in cortical neurons
-
DOI 10.1111/j.1471-4159.2008.05347.x
-
Shelat PB, Chalimoniuk M, Wang JH, Strosznajder JB, Lee JC, et al. (2008) Amyloid beta peptide and NMDA induce ROS from NADPH oxidase and AA release from cytosolic phospholipase A2 in cortical neurons. J Neurochem 106: 45-55. (Pubitemid 351840199)
-
(2008)
Journal of Neurochemistry
, vol.106
, Issue.1
, pp. 45-55
-
-
Shelat, P.B.1
Chalimoniuk, M.2
Wang, J.-H.3
Strosznajder, J.B.4
Lee, J.C.5
Sun, A.Y.6
Simonyi, A.7
Sun, G.Y.8
-
25
-
-
84872945822
-
Magnolia polyphenols attenuate oxidative and inflammatory responses in neurons and microglial cells
-
Chuang DY, Chan MH, Zong Y, Sheng W, He Y, et al. (2013) Magnolia polyphenols attenuate oxidative and inflammatory responses in neurons and microglial cells. J Neuroinflammation 10: 15.
-
(2013)
J Neuroinflammation
, vol.10
, pp. 15
-
-
Chuang, D.Y.1
Chan, M.H.2
Zong, Y.3
Sheng, W.4
He, Y.5
-
26
-
-
79952375934
-
Prolonged exposure of cortical neurons to oligomeric amyloid-beta impairs NMDA receptor function via NADPH oxidase-mediated ROS production: Protective effect of green tea (-)-epigallocatechin-3-gallate
-
He Y, Cui J, Lee JC, Ding S, Chalimoniuk M, et al. (2011) Prolonged exposure of cortical neurons to oligomeric amyloid-beta impairs NMDA receptor function via NADPH oxidase-mediated ROS production: protective effect of green tea (-)-epigallocatechin-3-gallate. ASN Neuro 3: e00050.
-
(2011)
ASN Neuro
, vol.3
-
-
He, Y.1
Cui, J.2
Lee, J.C.3
Ding, S.4
Chalimoniuk, M.5
-
27
-
-
79955008182
-
Inhibition of microglial phagocytosis is sufficient to prevent inflammatory neuronal death
-
Neher JJ, Neniskyte U, Zhao JW, Bal-Price A, Tolkovsky AM, et al. (2011) Inhibition of microglial phagocytosis is sufficient to prevent inflammatory neuronal death. J Immunol 186: 4973-4983.
-
(2011)
J Immunol
, vol.186
, pp. 4973-4983
-
-
Neher, J.J.1
Neniskyte, U.2
Zhao, J.W.3
Bal-Price, A.4
Tolkovsky, A.M.5
-
28
-
-
47849104490
-
HIV Infection of the Central Nervous System: Clinical Features and Neuropathogenesis
-
DOI 10.1016/j.ncl.2008.04.002, PII S0733861908000479
-
Boisse L, Gill MJ, Power C (2008) HIV infection of the central nervous system: clinical features and neuropathogenesis. Neurol Clin 26: 799-819, x. (Pubitemid 352037443)
-
(2008)
Neurologic Clinics
, vol.26
, Issue.3
, pp. 799-819
-
-
Boisse, L.1
Gill, M.J.2
Power, C.3
-
29
-
-
77952089812
-
Clinical correlates of HIV-associated neurocognitive disorders in South Africa
-
Joska JA, Fincham DS, Stein DJ, Paul RH, Seedat S (2010) Clinical correlates of HIV-associated neurocognitive disorders in South Africa. AIDS Behav 14: 371-378.
-
(2010)
AIDS Behav
, vol.14
, pp. 371-378
-
-
Joska, J.A.1
Fincham, D.S.2
Stein, D.J.3
Paul, R.H.4
Seedat, S.5
-
30
-
-
67649800742
-
NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation
-
Brennan AM, Suh SW, Won SJ, Narasimhan P, Kauppinen TM, et al. (2009) NADPH oxidase is the primary source of superoxide induced by NMDA receptor activation. Nat Neurosci 12: 857-863.
-
(2009)
Nat Neurosci
, vol.12
, pp. 857-863
-
-
Brennan, A.M.1
Suh, S.W.2
Won, S.J.3
Narasimhan, P.4
Kauppinen, T.M.5
-
31
-
-
33846506799
-
Induction of the formyl peptide receptor 2 in microglia by IFN-gamma and synergy with CD40 ligand
-
Chen K, Iribarren P, Huang J, Zhang L, Gong W, et al. (2007) Induction of the formyl peptide receptor 2 in microglia by IFN-gamma and synergy with CD40 ligand. J Immunol 178: 1759-1766. (Pubitemid 46154647)
-
(2007)
Journal of Immunology
, vol.178
, Issue.3
, pp. 1759-1766
-
-
Chen, K.1
Iribarren, P.2
Huang, J.3
Zhang, L.4
Gong, W.5
Cho, E.H.6
Lockett, S.7
Dunlop, N.M.8
Wang, J.M.9
-
32
-
-
30744435342
-
The role of NF-kappaB, IRF-1, and STAT-1alpha transcription factors in the iNOS gene induction by gliadin and IFN-gamma in RAW 264.7 macrophages
-
DOI 10.1007/s00109-005-0713-x
-
De Stefano D, Maiuri MC, Iovine B, Ialenti A, Bevilacqua MA, et al. (2006) The role of NF-kappaB, IRF-1, and STAT-1alpha transcription factors in the iNOS gene induction by gliadin and IFN-gamma in RAW 264.7 macrophages. J Mol Med (Berl) 84: 65-74. (Pubitemid 43099525)
-
(2006)
Journal of Molecular Medicine
, vol.84
, Issue.1
, pp. 65-74
-
-
De Stefane, D.1
Maiuri, M.C.2
Iovine, B.3
Ialenti, A.4
Bevilacqua, M.A.5
Carnuccio, R.6
-
33
-
-
77955486010
-
Ginsenoside Rh1 suppresses inducible nitric oxide synthase gene expression in IFN-gamma-stimulated microglia via modulation of JAK/STAT and ERK signaling pathways
-
Jung JS, Kim DH, Kim HS (2010) Ginsenoside Rh1 suppresses inducible nitric oxide synthase gene expression in IFN-gamma-stimulated microglia via modulation of JAK/STAT and ERK signaling pathways. Biochem Biophys Res Commun 397: 323-328.
-
(2010)
Biochem Biophys Res Commun
, vol.397
, pp. 323-328
-
-
Jung, J.S.1
Kim, D.H.2
Kim, H.S.3
-
34
-
-
84872234730
-
Chemical profiling with cytokine stimulating investigations of Sutherlandia frutescens
-
Faleschini MT MM, Harding N, Fouche G. (2013) Chemical profiling with cytokine stimulating investigations of Sutherlandia frutescens. South African Journal of Botany 85: 48-55.
-
(2013)
South African Journal of Botany
, vol.85
, pp. 48-55
-
-
Faleschini, M.T.M.M.1
Harding, N.2
Fouche, G.3
-
35
-
-
0029120469
-
Production of nitrite by primary rat astrocytes in response to pneumococci
-
Bernatowicz A, Kodel U, Frei K, Fontana A, Pfister HW (1995) Production of nitrite by primary rat astrocytes in response to pneumococci. J Neuroimmunol 60: 53-61.
-
(1995)
J Neuroimmunol
, vol.60
, pp. 53-61
-
-
Bernatowicz, A.1
Kodel, U.2
Frei, K.3
Fontana, A.4
Pfister, H.W.5
-
36
-
-
74349101457
-
Flavonol glycosides from the south African medicinal plant Sutherlandia frutescens
-
Fu X, Li XC, Wang YH, Avula B, Smillie TJ, et al. (2010) Flavonol glycosides from the south African medicinal plant Sutherlandia frutescens. Planta Med 76: 178-181.
-
(2010)
Planta Med
, vol.76
, pp. 178-181
-
-
Fu, X.1
Li, X.C.2
Wang, Y.H.3
Avula, B.4
Smillie, T.J.5
-
37
-
-
84881177499
-
Curcumin Protects Microglia and Primary Rat Cortical Neurons against HIV-1 gp120-Mediated Inflammation and Apoptosis
-
Guo L, Xing Y, Pan R, Jiang M, Gong Z, et al. (2013) Curcumin Protects Microglia and Primary Rat Cortical Neurons against HIV-1 gp120-Mediated Inflammation and Apoptosis. PLoS One 8: e70565.
-
(2013)
PLoS One
, vol.8
-
-
Guo, L.1
Xing, Y.2
Pan, R.3
Jiang, M.4
Gong, Z.5
|