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Volumn 158, Issue 1, 2014, Pages 15-24

Sublime microglia: Expanding roles for the guardians of the CNS

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; APOPTOSIS; BRAIN DEVELOPMENT; CENTRAL NERVOUS SYSTEM; COMPULSIVE PERSONALITY DISORDER; CONCEPTUAL FRAMEWORK; INFLAMMATORY CELL; LEARNING; MICROGLIA; NERVE CELL PLASTICITY; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PHAGOCYTOSIS; PRIORITY JOURNAL; REVIEW; SYNAPTIC TRANSMISSION;

EID: 84904009117     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2014.06.008     Document Type: Review
Times cited : (442)

References (90)
  • 2
    • 84872168596 scopus 로고    scopus 로고
    • Microglia: Scapegoat, saboteur, or something else?
    • A. Aguzzi, B.A. Barres, and M.L. Bennett Microglia: scapegoat, saboteur, or something else? Science 339 2013 156 161
    • (2013) Science , vol.339 , pp. 156-161
    • Aguzzi, A.1    Barres, B.A.2    Bennett, M.L.3
  • 3
    • 36448994709 scopus 로고    scopus 로고
    • Local self-renewal can sustain CNS microglia maintenance and function throughout adult life
    • B. Ajami, J.L. Bennett, C. Krieger, W. Tetzlaff, and F.M. Rossi Local self-renewal can sustain CNS microglia maintenance and function throughout adult life Nat. Neurosci. 10 2007 1538 1543
    • (2007) Nat. Neurosci. , vol.10 , pp. 1538-1543
    • Ajami, B.1    Bennett, J.L.2    Krieger, C.3    Tetzlaff, W.4    Rossi, F.M.5
  • 4
    • 0032830639 scopus 로고    scopus 로고
    • Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
    • R.E. Amir, I.B. Van den Veyver, M. Wan, C.Q. Tran, U. Francke, and H.Y. Zoghbi Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2 Nat. Genet. 23 1999 185 188
    • (1999) Nat. Genet. , vol.23 , pp. 185-188
    • Amir, R.E.1    Van Den Veyver, I.B.2    Wan, M.3    Tran, C.Q.4    Francke, U.5    Zoghbi, H.Y.6
  • 7
    • 84864487226 scopus 로고    scopus 로고
    • P2X4R+ microglia drive neuropathic pain
    • S. Beggs, T. Trang, and M.W. Salter P2X4R+ microglia drive neuropathic pain Nat. Neurosci. 15 2012 1068 1073
    • (2012) Nat. Neurosci. , vol.15 , pp. 1068-1073
    • Beggs, S.1    Trang, T.2    Salter, M.W.3
  • 8
    • 33846887598 scopus 로고    scopus 로고
    • Microglial control of neuronal death and synaptic properties
    • A. Bessis, C. Béchade, D. Bernard, and A. Roumier Microglial control of neuronal death and synaptic properties Glia 55 2007 233 238
    • (2007) Glia , vol.55 , pp. 233-238
    • Bessis, A.1    Béchade, C.2    Bernard, D.3    Roumier, A.4
  • 9
    • 84888348687 scopus 로고    scopus 로고
    • TGF-β signaling regulates neuronal C1q expression and developmental synaptic refinement
    • A.R. Bialas, and B. Stevens TGF-β signaling regulates neuronal C1q expression and developmental synaptic refinement Nat. Neurosci. 16 2013 1773 1782
    • (2013) Nat. Neurosci. , vol.16 , pp. 1773-1782
    • Bialas, A.R.1    Stevens, B.2
  • 11
    • 79951581460 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor: Findings in schizophrenia
    • P.F. Buckley, A. Pillai, and K.R. Howell Brain-derived neurotrophic factor: findings in schizophrenia Curr. Opin. Psychiatry 24 2011 122 127
    • (2011) Curr. Opin. Psychiatry , vol.24 , pp. 122-127
    • Buckley, P.F.1    Pillai, A.2    Howell, K.R.3
  • 13
    • 0033568871 scopus 로고    scopus 로고
    • Relative contribution of endogenous neurotrophins in hippocampal long-term potentiation
    • G. Chen, R. Kolbeck, Y.A. Barde, T. Bonhoeffer, and A. Kossel Relative contribution of endogenous neurotrophins in hippocampal long-term potentiation J. Neurosci. 19 1999 7983 7990
    • (1999) J. Neurosci. , vol.19 , pp. 7983-7990
    • Chen, G.1    Kolbeck, R.2    Barde, Y.A.3    Bonhoeffer, T.4    Kossel, A.5
  • 18
    • 84874586343 scopus 로고    scopus 로고
    • Microglia regulate the number of neural precursor cells in the developing cerebral cortex
    • C.L. Cunningham, V. Martínez-Cerdeño, and S.C. Noctor Microglia regulate the number of neural precursor cells in the developing cerebral cortex J. Neurosci. 33 2013 4216 4233
    • (2013) J. Neurosci. , vol.33 , pp. 4216-4233
    • Cunningham, C.L.1    Martínez-Cerdeño, V.2    Noctor, S.C.3
  • 19
    • 79955554997 scopus 로고    scopus 로고
    • Immune and nonimmune components orchestrate the pathogenesis of inflammatory bowel disease
    • S. Danese Immune and nonimmune components orchestrate the pathogenesis of inflammatory bowel disease Am. J. Physiol. Gastrointest. Liver Physiol. 300 2011 G716 G722
    • (2011) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.300
    • Danese, S.1
  • 23
    • 80055051144 scopus 로고    scopus 로고
    • Absence of colony stimulation factor-1 receptor results in loss of microglia, disrupted brain development and olfactory deficits
    • B. Erblich, L. Zhu, A.M. Etgen, K. Dobrenis, and J.W. Pollard Absence of colony stimulation factor-1 receptor results in loss of microglia, disrupted brain development and olfactory deficits PLoS ONE 6 2011 e26317
    • (2011) PLoS ONE , vol.6 , pp. 26317
    • Erblich, B.1    Zhu, L.2    Etgen, A.M.3    Dobrenis, K.4    Pollard, J.W.5
  • 26
    • 3242766671 scopus 로고    scopus 로고
    • Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer's disease
    • M.I. Fonseca, J. Zhou, M. Botto, and A.J. Tenner Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer's disease J. Neurosci. 24 2004 6457 6465
    • (2004) J. Neurosci. , vol.24 , pp. 6457-6465
    • Fonseca, M.I.1    Zhou, J.2    Botto, M.3    Tenner, A.J.4
  • 27
    • 0031934936 scopus 로고    scopus 로고
    • Microglia-derived nerve growth factor causes cell death in the developing retina
    • J.M. Frade, and Y.A. Barde Microglia-derived nerve growth factor causes cell death in the developing retina Neuron 20 1998 35 41
    • (1998) Neuron , vol.20 , pp. 35-41
    • Frade, J.M.1    Barde, Y.A.2
  • 29
    • 84888340976 scopus 로고    scopus 로고
    • The role of microglia in adult hippocampal neurogenesis
    • C. Gemma, and A.D. Bachstetter The role of microglia in adult hippocampal neurogenesis Front. Cell. Neurosci. 7 2013 229
    • (2013) Front. Cell. Neurosci. , vol.7 , pp. 229
    • Gemma, C.1    Bachstetter, A.D.2
  • 32
    • 84869161077 scopus 로고    scopus 로고
    • Regulation of microglia development and homeostasis
    • M. Greter, and M. Merad Regulation of microglia development and homeostasis Glia 61 2013 121 127
    • (2013) Glia , vol.61 , pp. 121-127
    • Greter, M.1    Merad, M.2
  • 35
    • 84876775203 scopus 로고    scopus 로고
    • Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes
    • D. Hashimoto, A. Chow, C. Noizat, P. Teo, M.B. Beasley, M. Leboeuf, C.D. Becker, P. See, J. Price, and D. Lucas et al. Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes Immunity 38 2013 792 804
    • (2013) Immunity , vol.38 , pp. 792-804
    • Hashimoto, D.1    Chow, A.2    Noizat, C.3    Teo, P.4    Beasley, M.B.5    Leboeuf, M.6    Becker, C.D.7    See, P.8    Price, J.9    Lucas, D.10
  • 37
    • 84867796425 scopus 로고    scopus 로고
    • Deficiency of the microglial receptor CX3CR1 impairs postnatal functional development of thalamocortical synapses in the barrel cortex
    • M. Hoshiko, I. Arnoux, E. Avignone, N. Yamamoto, and E. Audinat Deficiency of the microglial receptor CX3CR1 impairs postnatal functional development of thalamocortical synapses in the barrel cortex J. Neurosci. 32 2012 15106 15111
    • (2012) J. Neurosci. , vol.32 , pp. 15106-15111
    • Hoshiko, M.1    Arnoux, I.2    Avignone, E.3    Yamamoto, N.4    Audinat, E.5
  • 38
    • 0029963657 scopus 로고    scopus 로고
    • Synaptic activity and the construction of cortical circuits
    • L.C. Katz, and C.J. Shatz Synaptic activity and the construction of cortical circuits Science 274 1996 1133 1138
    • (1996) Science , vol.274 , pp. 1133-1138
    • Katz, L.C.1    Shatz, C.J.2
  • 40
    • 84872176512 scopus 로고    scopus 로고
    • Microglia: New roles for the synaptic stripper
    • H. Kettenmann, F. Kirchhoff, and A. Verkhratsky Microglia: new roles for the synaptic stripper Neuron 77 2013 10 18
    • (2013) Neuron , vol.77 , pp. 10-18
    • Kettenmann, H.1    Kirchhoff, F.2    Verkhratsky, A.3
  • 42
    • 84876494975 scopus 로고    scopus 로고
    • Impaired glutamate recycling and GluN2B-mediated neuronal calcium overload in mice lacking TGF-β1 in the CNS
    • T. Koeglsperger, S. Li, C. Brenneis, J.L. Saulnier, L. Mayo, Y. Carrier, D.J. Selkoe, and H.L. Weiner Impaired glutamate recycling and GluN2B-mediated neuronal calcium overload in mice lacking TGF-β1 in the CNS Glia 61 2013 985 1002
    • (2013) Glia , vol.61 , pp. 985-1002
    • Koeglsperger, T.1    Li, S.2    Brenneis, C.3    Saulnier, J.L.4    Mayo, L.5    Carrier, Y.6    Selkoe, D.J.7    Weiner, H.L.8
  • 43
    • 84869192542 scopus 로고    scopus 로고
    • Purinergic receptors in microglia: Functional modal shifts of microglia mediated by P2 and P1 receptors
    • S. Koizumi, K. Ohsawa, K. Inoue, and S. Kohsaka Purinergic receptors in microglia: functional modal shifts of microglia mediated by P2 and P1 receptors Glia 61 2013 47 54
    • (2013) Glia , vol.61 , pp. 47-54
    • Koizumi, S.1    Ohsawa, K.2    Inoue, K.3    Kohsaka, S.4
  • 44
    • 0032213168 scopus 로고    scopus 로고
    • Neurotrophin-dependent modulation of glutamatergic synaptic transmission in the mammalian CNS
    • V. Lessmann Neurotrophin-dependent modulation of glutamatergic synaptic transmission in the mammalian CNS Gen. Pharmacol. 31 1998 667 674
    • (1998) Gen. Pharmacol. , vol.31 , pp. 667-674
    • Lessmann, V.1
  • 45
    • 84870832562 scopus 로고    scopus 로고
    • Reciprocal regulation between resting microglial dynamics and neuronal activity in vivo
    • Y. Li, X.F. Du, C.S. Liu, Z.L. Wen, and J.L. Du Reciprocal regulation between resting microglial dynamics and neuronal activity in vivo Dev. Cell 23 2012 1189 1202
    • (2012) Dev. Cell , vol.23 , pp. 1189-1202
    • Li, Y.1    Du, X.F.2    Liu, C.S.3    Wen, Z.L.4    Du, J.L.5
  • 48
    • 84861123981 scopus 로고    scopus 로고
    • IRF8 is a critical transcription factor for transforming microglia into a reactive phenotype
    • T. Masuda, M. Tsuda, R. Yoshinaga, H. Tozaki-Saitoh, K. Ozato, T. Tamura, and K. Inoue IRF8 is a critical transcription factor for transforming microglia into a reactive phenotype Cell Rep. 1 2012 334 340
    • (2012) Cell Rep. , vol.1 , pp. 334-340
    • Masuda, T.1    Tsuda, M.2    Yoshinaga, R.3    Tozaki-Saitoh, H.4    Ozato, K.5    Tamura, T.6    Inoue, K.7
  • 49
    • 84873743410 scopus 로고    scopus 로고
    • M1 and M2 Macrophages: Oracles of Health and Disease
    • C.D. Mills M1 and M2 Macrophages: Oracles of Health and Disease Crit. Rev. Immunol. 32 2012 463 488
    • (2012) Crit. Rev. Immunol. , vol.32 , pp. 463-488
    • Mills, C.D.1
  • 51
    • 0036321329 scopus 로고    scopus 로고
    • Ceramide activates microglia to enhance the production/secretion of brain-derived neurotrophic factor (BDNF) without induction of deleterious factors in vitro
    • K. Nakajima, Y. Tohyama, S. Kohsaka, and T. Kurihara Ceramide activates microglia to enhance the production/secretion of brain-derived neurotrophic factor (BDNF) without induction of deleterious factors in vitro J. Neurochem. 80 2002 697 705
    • (2002) J. Neurochem. , vol.80 , pp. 697-705
    • Nakajima, K.1    Tohyama, Y.2    Kohsaka, S.3    Kurihara, T.4
  • 52
    • 19744380563 scopus 로고    scopus 로고
    • Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
    • A. Nimmerjahn, F. Kirchhoff, and F. Helmchen Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo Science 308 2005 1314 1318
    • (2005) Science , vol.308 , pp. 1314-1318
    • Nimmerjahn, A.1    Kirchhoff, F.2    Helmchen, F.3
  • 60
    • 78149438403 scopus 로고    scopus 로고
    • Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice
    • N. Saederup, A.E. Cardona, K. Croft, M. Mizutani, A.C. Cotleur, C.L. Tsou, R.M. Ransohoff, and I.F. Charo Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice PLoS ONE 5 2010 e13693
    • (2010) PLoS ONE , vol.5 , pp. 13693
    • Saederup, N.1    Cardona, A.E.2    Croft, K.3    Mizutani, M.4    Cotleur, A.C.5    Tsou, C.L.6    Ransohoff, R.M.7    Charo, I.F.8
  • 62
    • 84869157553 scopus 로고    scopus 로고
    • The "quad-partite" synapse: Microglia-synapse interactions in the developing and mature CNS
    • D.P. Schafer, E.K. Lehrman, and B. Stevens The "quad-partite" synapse: microglia-synapse interactions in the developing and mature CNS Glia 61 2013 24 36
    • (2013) Glia , vol.61 , pp. 24-36
    • Schafer, D.P.1    Lehrman, E.K.2    Stevens, B.3
  • 65
    • 1542317053 scopus 로고    scopus 로고
    • Macrophage-derived tumor necrosis factor alpha, an early developmental signal for motoneuron death
    • F. Sedel, C. Béchade, S. Vyas, and A. Triller Macrophage-derived tumor necrosis factor alpha, an early developmental signal for motoneuron death J. Neurosci. 24 2004 2236 2246
    • (2004) J. Neurosci. , vol.24 , pp. 2236-2246
    • Sedel, F.1    Béchade, C.2    Vyas, S.3    Triller, A.4
  • 66
    • 0035868717 scopus 로고    scopus 로고
    • Neurogenesis in the adult is involved in the formation of trace memories
    • T.J. Shors, G. Miesegaes, A. Beylin, M. Zhao, T. Rydel, and E. Gould Neurogenesis in the adult is involved in the formation of trace memories Nature 410 2001 372 376
    • (2001) Nature , vol.410 , pp. 372-376
    • Shors, T.J.1    Miesegaes, G.2    Beylin, A.3    Zhao, M.4    Rydel, T.5    Gould, E.6
  • 68
    • 84876488443 scopus 로고    scopus 로고
    • The transcription factor PU.1 is critical for viability and function of human brain microglia
    • A.M. Smith, H.M. Gibbons, R.L. Oldfield, P.M. Bergin, E.W. Mee, R.L. Faull, and M. Dragunow The transcription factor PU.1 is critical for viability and function of human brain microglia Glia 61 2013 929 942
    • (2013) Glia , vol.61 , pp. 929-942
    • Smith, A.M.1    Gibbons, H.M.2    Oldfield, R.L.3    Bergin, P.M.4    Mee, E.W.5    Faull, R.L.6    Dragunow, M.7
  • 69
    • 33646199097 scopus 로고    scopus 로고
    • Synaptic scaling mediated by glial TNF-alpha
    • D. Stellwagen, and R.C. Malenka Synaptic scaling mediated by glial TNF-alpha Nature 440 2006 1054 1059
    • (2006) Nature , vol.440 , pp. 1054-1059
    • Stellwagen, D.1    Malenka, R.C.2
  • 71
    • 0029999022 scopus 로고    scopus 로고
    • Synaptic modulation by neurotrophic factors: Differential and synergistic effects of brain-derived neurotrophic factor and ciliary neurotrophic factor
    • R. Stoop, and M.M. Poo Synaptic modulation by neurotrophic factors: differential and synergistic effects of brain-derived neurotrophic factor and ciliary neurotrophic factor J. Neurosci. 16 1996 3256 3264
    • (1996) J. Neurosci. , vol.16 , pp. 3256-3264
    • Stoop, R.1    Poo, M.M.2
  • 73
    • 63849192564 scopus 로고    scopus 로고
    • P2X4-receptor-mediated synthesis and release of brain-derived neurotrophic factor in microglia is dependent on calcium and p38-mitogen-activated protein kinase activation
    • T. Trang, S. Beggs, X. Wan, and M.W. Salter P2X4-receptor-mediated synthesis and release of brain-derived neurotrophic factor in microglia is dependent on calcium and p38-mitogen-activated protein kinase activation J. Neurosci. 29 2009 3518 3528
    • (2009) J. Neurosci. , vol.29 , pp. 3518-3528
    • Trang, T.1    Beggs, S.2    Wan, X.3    Salter, M.W.4
  • 74
    • 78649976052 scopus 로고    scopus 로고
    • Microglial interactions with synapses are modulated by visual experience
    • M.E. Tremblay, R.L. Lowery, and A.K. Majewska Microglial interactions with synapses are modulated by visual experience PLoS Biol. 8 2010 e1000527
    • (2010) PLoS Biol. , vol.8 , pp. 1000527
    • Tremblay, M.E.1    Lowery, R.L.2    Majewska, A.K.3
  • 78
    • 77449099299 scopus 로고    scopus 로고
    • Mechanisms underlying fibronectin-induced up-regulation of P2X4R expression in microglia: Distinct roles of PI3K-Akt and MEK-ERK signalling pathways
    • M. Tsuda, E. Toyomitsu, M. Kometani, H. Tozaki-Saitoh, and K. Inoue Mechanisms underlying fibronectin-induced up-regulation of P2X4R expression in microglia: distinct roles of PI3K-Akt and MEK-ERK signalling pathways J. Cell. Mol. Med. 13 9B 2009 3251 3259
    • (2009) J. Cell. Mol. Med. , vol.13 , Issue.9 B , pp. 3251-3259
    • Tsuda, M.1    Toyomitsu, E.2    Kometani, M.3    Tozaki-Saitoh, H.4    Inoue, K.5
  • 79
    • 84869179304 scopus 로고    scopus 로고
    • Microglia and intractable chronic pain
    • M. Tsuda, S. Beggs, M.W. Salter, and K. Inoue Microglia and intractable chronic pain Glia 61 2013 55 61
    • (2013) Glia , vol.61 , pp. 55-61
    • Tsuda, M.1    Beggs, S.2    Salter, M.W.3    Inoue, K.4
  • 80
    • 84876939061 scopus 로고    scopus 로고
    • Layer v cortical neurons require microglial support for survival during postnatal development
    • M. Ueno, Y. Fujita, T. Tanaka, Y. Nakamura, J. Kikuta, M. Ishii, and T. Yamashita Layer V cortical neurons require microglial support for survival during postnatal development Nat. Neurosci. 16 2013 543 551
    • (2013) Nat. Neurosci. , vol.16 , pp. 543-551
    • Ueno, M.1    Fujita, Y.2    Tanaka, T.3    Nakamura, Y.4    Kikuta, J.5    Ishii, M.6    Yamashita, T.7
  • 82
    • 65249157852 scopus 로고    scopus 로고
    • Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals
    • H. Wake, A.J. Moorhouse, S. Jinno, S. Kohsaka, and J. Nabekura Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals J. Neurosci. 29 2009 3974 3980
    • (2009) J. Neurosci. , vol.29 , pp. 3974-3980
    • Wake, H.1    Moorhouse, A.J.2    Jinno, S.3    Kohsaka, S.4    Nabekura, J.5
  • 83
    • 84875870356 scopus 로고    scopus 로고
    • Microglia: Actively surveying and shaping neuronal circuit structure and function
    • H. Wake, A.J. Moorhouse, A. Miyamoto, and J. Nabekura Microglia: actively surveying and shaping neuronal circuit structure and function Trends Neurosci. 36 2013 209 217
    • (2013) Trends Neurosci. , vol.36 , pp. 209-217
    • Wake, H.1    Moorhouse, A.J.2    Miyamoto, A.3    Nabekura, J.4
  • 84
    • 51149091666 scopus 로고    scopus 로고
    • Developmental neuronal death in hippocampus requires the microglial CD11b integrin and DAP12 immunoreceptor
    • S. Wakselman, C. Béchade, A. Roumier, D. Bernard, A. Triller, and A. Bessis Developmental neuronal death in hippocampus requires the microglial CD11b integrin and DAP12 immunoreceptor J. Neurosci. 28 2008 8138 8143
    • (2008) J. Neurosci. , vol.28 , pp. 8138-8143
    • Wakselman, S.1    Béchade, C.2    Roumier, A.3    Bernard, D.4    Triller, A.5    Bessis, A.6
  • 86
    • 72449182586 scopus 로고    scopus 로고
    • Stably maintained dendritic spines are associated with lifelong memories
    • G. Yang, F. Pan, and W.B. Gan Stably maintained dendritic spines are associated with lifelong memories Nature 462 2009 920 924
    • (2009) Nature , vol.462 , pp. 920-924
    • Yang, G.1    Pan, F.2    Gan, W.B.3
  • 90
    • 84897401619 scopus 로고    scopus 로고
    • Microglial CR3 activation triggers long-term synaptic depression in the hippocampus via NADPH oxidase
    • J. Zhang, A. Malik, H.B. Choi, R.W. Ko, L. Dissing-Olesen, and B.A. MacVicar Microglial CR3 activation triggers long-term synaptic depression in the hippocampus via NADPH oxidase Neuron 82 2014 195 207
    • (2014) Neuron , vol.82 , pp. 195-207
    • Zhang, J.1    Malik, A.2    Choi, H.B.3    Ko, R.W.4    Dissing-Olesen, L.5    MacVicar, B.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.