Identification and quantitative analysis of cellular proteins affected by treatment with withaferin a using a SILAC-based proteomics approach

Journal of Ethnopharmacology

Volumn 175, Issue , 2015, Pages 86-92

  Narayan, Malathi ^a   Seeley, Kent W ^b   Jinwal, Umesh K ^a  

^a UNIVERSITY OF SOUTH FLORIDA   (United States)

^b UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

Ashwagandha; Microglial cell; SILAC based proteomics analysis; Withaferin A; Withania somnifera

Indexed keywords

ADENOSINE MONOPHOSPHATE DEAMINASE; ALCOHOL DEHYDROGENASE; ALDEHYDE REDUCTASE; AMP DEAMINASE 3; CATALASE; CELL PROTEIN; GLUCOSE 6 PHOSPHATE 1 DEHYDROGENASE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTATHIONE TRANSFERASE P1; HEAT SHOCK PROTEIN 90 ALPHA; HEME OXYGENASE 1; HIGH MOBILITY GROUP PROTEIN; KARYOPHERIN; KI 67 ANTIGEN; LIPOCORTIN 1; LIPOCORTIN 4; PEPTIDYLPROLYL ISOMERASE; PEPTIDYLPROLYL ISOMERASE D; PEROXIREDOXIN 1; PEROXIREDOXIN 6; PHOSPHOGLUCOMUTASE; SEQUESTOSOME 1; STABLE ISOTOPE; SYNAPTOGYRIN; THIOREDOXIN REDUCTASE 1; TRANSALDOLASE; TRANSGELIN; UNCLASSIFIED DRUG; WITHAFERIN A; HEAT SHOCK PROTEIN; WITHANOLIDE;

ANIMAL CELL; ARTICLE; CARBOHYDRATE METABOLISM; CONTROLLED STUDY; DRUG MECHANISM; FREE RADICAL SCAVENGING ASSAY; MICROGLIA; MICROGLIAL CELL CULTURE; MOUSE; NONHUMAN; PHENOTYPE; PRIMARY CELL CULTURE; PROTEIN ANALYSIS; PROTEOMICS; QUANTITATIVE ANALYSIS; SILAC BASED PROTEOMICS; TANDEM MASS SPECTROMETRY; UPREGULATION; ANIMAL; CELL DEATH; CELL LINE; CELL SURVIVAL; DRUG EFFECTS; ISOTOPE LABELING; MASS SPECTROMETRY; METABOLISM; PROCEDURES;

ANIMALS; ANNEXIN A1; CARBOHYDRATE METABOLISM; CELL DEATH; CELL LINE; CELL SURVIVAL; HEAT-SHOCK PROTEINS; ISOTOPE LABELING; MASS SPECTROMETRY; MICE; MICROGLIA; PROTEOMICS; WITHANOLIDES;

EID: 84942523832     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2015.09.024     Document Type: Article

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