Quercetin inhibits lipopolysaccharide-induced nitric oxide production in BV2 microglial cells by suppressing the NF-κB pathway and activating the Nrf2-dependent HO-1 pathway

International Immunopharmacology

Volumn 17, Issue 3, 2013, Pages 808-813

  Kang, Chang Hee ^a   Choi, Yung Hyun ^b   Moon, Sung Kwon ^c   Kim, Wun Jae ^d   Kim, Gi Young ^a  

^a Jeju National University   (South Korea)

^b Dong Eui University   (South Korea)

^c Chung Ang University   (South Korea)

^d Chungbuk National University College of Medicine   (South Korea)

Author keywords

2 related factor 2; Heme oxgenase 1; Nitric oxide; Nitric oxide synthase; Nuclear factor B; Nuclear factor 2 erythroid; Quercetin

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; NITRIC OXIDE; PROTEASOME INHIBITOR; PROTOPORPHYRIN COBALT; QUERCETIN; SCAVENGER; TRANSCRIPTION FACTOR NRF2;

ANIMAL CELL; ANIMAL CELL CULTURE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BINDING AFFINITY; CELL VIABILITY; CHEMOPROPHYLAXIS; CONTROLLED STUDY; DNA BINDING; DNA FRAGMENTATION; ENZYME ACTIVATION; ENZYME INHIBITION; GEL MOBILITY SHIFT ASSAY; GENE SILENCING; MICROGLIA; MOUSE; NERVOUS SYSTEM INFLAMMATION; NITROSATIVE STRESS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DNA BINDING; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

HEME OXGENASE-1; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NUCLEAR FACTOR-2-ERYTHROID 2-RELATED FACTOR 2; NUCLEAR FACTOR-ΚB; QUERCETIN;

ANIMALS; CELL LINE; HEME OXYGENASE-1; LIPOPOLYSACCHARIDES; MEMBRANE PROTEINS; MICE; MICROGLIA; NEUROPROTECTIVE AGENTS; NF-E2-RELATED FACTOR 2; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; QUERCETIN;

EID: 84884921233     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2013.09.009     Document Type: Article

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