Quercetin attenuates inflammatory responses in BV-2 microglial cells: Role of MAPKs on the Nrf2 pathway and induction of heme oxygenase-1

PLoS ONE

Volumn 10, Issue 10, 2015, Pages

  Sun, Grace Y ^a,b   Chen, Zihong ^a,b   Jasmer, Kimberly J ^b   Chuang, Dennis Y ^b   Gu, Zezong ^a,b   Hannink, Mark ^a,b   Simonyi, Agnes ^a,b  

^a University of Missouri   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYANIDIN CHLORIDE; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; QUERCETIN; TRANSCRIPTION FACTOR NRF2; LIPOPOLYSACCHARIDE; NFE2L2 PROTEIN, MOUSE;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL STRESS; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; ENDOTOXIC STRESS; ENZYME INDUCTION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; MICROGLIA; MOUSE; NONHUMAN; PROTEIN EXPRESSION; UPREGULATION; ANIMAL; BIOSYNTHESIS; CHEMICALLY INDUCED; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; INFLAMMATION; MACROPHAGE; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; GENE EXPRESSION REGULATION; HEME OXYGENASE-1; HUMANS; INFLAMMATION; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICROGLIA; NF-E2-RELATED FACTOR 2; NF-KAPPA B; NITRIC OXIDE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; QUERCETIN; SIGNAL TRANSDUCTION;

EID: 84949683586     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0141509     Document Type: Article

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