Sulforaphane suppresses LPS-induced inflammation in primary rat microglia

Inflammation Research

Volumn 59, Issue 6, 2010, Pages 443-450

  Brandenburg, Lars Ove ^a,b   Kipp, Markus ^a   Lucius, Ralph ^b   Pufe, Thomas ^a   Wruck, Christoph J ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b UNIVERSITY OF KIEL   (Germany)

Author keywords

LPS; Neuroinflammation; Oxidative stress; Plant antioxidants; Signal transduction

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; LUCIFERASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; NITRIC OXIDE; STRESS ACTIVATED PROTEIN KINASE; SULFONIC ACID DERIVATIVE; SULFORAPHANE; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR NRF2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL CULTURE; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME RELEASE; MICROGLIA; MOUSE; NERVOUS SYSTEM INFLAMMATION; NEUROPROTECTION; NEWBORN; NONHUMAN; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; WESTERN BLOTTING;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BLOTTING, WESTERN; CELLS, CULTURED; CYTOKINES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; INFLAMMATION; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LIPOPOLYSACCHARIDES; LUCIFERASES; MICROGLIA; NF-E2-RELATED FACTOR 2; NF-KAPPA B; NITRITES; PHOSPHORYLATION; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; THIOCYANATES; TRANSCRIPTION FACTOR AP-1;

EID: 77953324869     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-009-0116-5     Document Type: Article

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