Pro-inflammatory cytokines and lipopolysaccharide induce changes in cell morphology, and upregulation of ERK1/2, iNOS and sPLA2-IIA expression in astrocytes and microglia

Journal of Neuroinflammation

Volumn 8, Issue , 2011, Pages

  Sheng, Wenwen ^a   Zong, Yijia ^b   Mohammad, Arwa ^b   Ajit, Deepa ^a,b   Cui, Jiankun ^a   Han, Dongdong ^a   Hamilton, Jennifer L ^a,b   Simonyi, Agnes ^a   Sun, Albert Y ^a   Gu, Zezong ^a   Hong, Jau Shyong ^c   Weisman, Gary A ^a,b   Sun, Grace Y ^a,b  

^a University of Missouri   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

BV 2; DITNC; ERK1 2; Filopodia; HAPI; INOS; Primary astrocytes; Primary microglial cells; SPLA2 IIA

Indexed keywords

GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NITRIC OXIDE; SECRETORY PHOSPHOLIPASE A2; SECRETORY PHOSPHOLIPASE A2 IIA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CYTOKINE; NOS2 PROTEIN, RAT; PHOSPHOLIPASE A2 GROUP II;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL IMMORTALIZATION; CELL STRUCTURE; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME ACTIVATION; ENZYME REGULATION; GENE; GENE EXPRESSION REGULATION; GENE INDUCTION; IMMUNOREACTIVITY; MICROGLIA; MOUSE; NONHUMAN; PROTEIN EXPRESSION; RAT; SECRETORY PHOSPHOLIPASE A2 IIA GENE; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL SHAPE; CYTOLOGY; DRUG EFFECT; FEMALE; GENETICS; IMMUNOLOGY; INFLAMMATION; METABOLISM; PREGNANCY; PSEUDOPODIUM; SPRAGUE DAWLEY RAT; ULTRASTRUCTURE;

ANIMALS; ASTROCYTES; CELL SHAPE; CELLS, CULTURED; CYTOKINES; FEMALE; GROUP II PHOSPHOLIPASES A2; INFLAMMATION; INTERFERON-GAMMA; LIPOPOLYSACCHARIDES; MICE; MICE, INBRED C57BL; MICROGLIA; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PREGNANCY; PSEUDOPODIA; RATS; RATS, SPRAGUE-DAWLEY;

EID: 80053175796     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-8-121     Document Type: Article

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