Manipulation of interleukin-1β and interleukin-18 production by yersinia pestis effectors YopJ and YopM and redundant impact on virulence

Journal of Biological Chemistry

Volumn 291, Issue 19, 2016, Pages 9894-9905

  Ratner, Dmitry ^a   Orning, M Pontus A ^a,b   Starheim, Kristian K ^a,b   Marty Roix, Robyn ^a   Proulx, Megan K ^a   Goguen, Jon D ^a   Lien, Egil ^a,b  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIA; CELL DEATH;

ANTI-MICROBIAL EFFECTS; CYTOKINE PRODUCTION; GRAM-NEGATIVE BACTERIA; INFLAMMATORY MEDIATORS; INNATE IMMUNE RESPONSE; INNATE IMMUNITY; TWO-STEP MECHANISMS; TYPE III SECRETION SYSTEM;

IMMUNE SYSTEM;

BACTERIAL PROTEIN; CASPASE 8; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; UNCLASSIFIED DRUG; YERSINIA OUTER PROTEIN J; YERSINIA OUTER PROTEIN M; OUTER MEMBRANE PROTEIN; YOPM PROTEIN, YERSINIA; YOPP PROTEIN, YERSINIA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL VIRULENCE; BONE MARROW DERIVED DENDRITIC CELL; BONE MARROW DERIVED MACROPHAGE; CELL DEATH; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME ACTIVITY; ENZYME INHIBITION; GENE DELETION; HOST PATHOGEN INTERACTION; IN VITRO STUDY; IN VIVO STUDY; INNATE IMMUNITY; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS REGULATION; TYPE III SECRETION SYSTEM; YERSINIA PESTIS; ANIMAL; CELL CULTURE; GENETICS; IMMUNOLOGY; MACROPHAGE; METABOLISM; MICROBIOLOGY; PATHOGENICITY; REAL TIME POLYMERASE CHAIN REACTION; VIRULENCE; YERSINIA INFECTION;

ANIMALS; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL PROTEINS; CELLS, CULTURED; IMMUNITY, INNATE; INFLAMMASOMES; INTERLEUKIN-18; INTERLEUKIN-1BETA; MACROPHAGES; MICE; REAL-TIME POLYMERASE CHAIN REACTION; VIRULENCE; YERSINIA INFECTIONS; YERSINIA PESTIS;

EID: 84966412907     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.697698     Document Type: Article

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