Inflammasome activation in response to the yersinia type III secretion system requires hyperinjection of translocon proteins YopB and YopD

mBio

Volumn 6, Issue 1, 2015, Pages

  Zwack, Erin E ^a   Snyder, Annelise G ^a,f   Wynosky Dolfi, Meghan A ^a   Ruthel, Gordon ^a   Philip, Naomi H ^a,b   Marketon, Melanie M ^c   Francis, Matthew S ^d   Bliska, James B ^e   Brodsky, Igor E ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c INDIANA UNIVERSITY   (United States)

^d UMEÅ UNIVERSITY   (Sweden)

^e STONY BROOK UNIVERSITY   (United States)

^f UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 11; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; INTERLEUKIN 6; LACTATE DEHYDROGENASE; TOLL LIKE RECEPTOR; TRANSLOCON; TRANSLOCON YOPB; TRANSLOCON YOPD; TRANSLOCON YOPK; UNCLASSIFIED DRUG; OUTER MEMBRANE PROTEIN; TYPE III SECRETION SYSTEM; YOPB PROTEIN, YERSINIA; YOPD PROTEIN, YERSINIA;

AMINO ACID SUBSTITUTION; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; CELLULAR DISTRIBUTION; COMPLEX FORMATION; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOSOL; ENZYME ACTIVATION; ENZYME RELEASE; GENE DELETION; GENE INTERACTION; GENETIC VARIABILITY; HEMOLYSIS; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; LCRH GENE; NONHUMAN; PHENOTYPIC VARIATION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SPOROGENESIS; TYPE III SECRETION SYSTEM; UPREGULATION; YERSINIA PSEUDOTUBERCULOSIS; YERSINIA PSEUDOTUBERCULOSIS INFECTION; YOPB GENE; YOPD GENE; YOPK GENE; ANIMAL; CELL LINE; CELL SURVIVAL; EPITHELIUM CELL; MACROPHAGE; METABOLISM; MICROBIOLOGY; MOUSE; PHYSIOLOGY; YERSINIA;

YERSINIA; YERSINIA PSEUDOTUBERCULOSIS;

ANIMALS; BACTERIAL OUTER MEMBRANE PROTEINS; CELL LINE; CELL SURVIVAL; EPITHELIAL CELLS; HUMANS; INFLAMMASOMES; MACROPHAGES; MICE; PROTEIN TRANSPORT; TYPE III SECRETION SYSTEMS; YERSINIA;

EID: 84924217271     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.02095-14     Document Type: Article

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