메뉴 건너뛰기




Volumn 11, Issue 4, 2012, Pages 337-351

Yersinia pseudotuberculosis effector YopJ subverts the Nod2/RICK/TAK1 pathway and activates caspase-1 to induce intestinal barrier dysfunction

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; APOPTOSIS REGULATORY PROTEIN; BACTERIAL ENZYME; CASPASE RECRUITMENT DOMAIN PROTEIN 15; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; RICK PROTEIN; TRANSFORMING GROWTH FACTOR BETA ACTIVATED KINASE 1; UNCLASSIFIED DRUG; YOPJ PROTEIN;

EID: 84860001887     PISSN: 19313128     EISSN: 19346069     Source Type: Journal    
DOI: 10.1016/j.chom.2012.02.009     Document Type: Article
Times cited : (94)

References (46)
  • 1
    • 45949086355 scopus 로고    scopus 로고
    • Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeability
    • Al-Sadi, R., Ye, D., Dokladny, K., and Ma, T.Y. (2008). Mechanism of IL-1beta-induced increase in intestinal epithelial tight junction permeability. J. Immunol. 180, 5653-5661.
    • (2008) J. Immunol. , vol.180 , pp. 5653-5661
    • Al-Sadi, R.1    Ye, D.2    Dokladny, K.3    Ma, T.Y.4
  • 2
    • 34447286255 scopus 로고    scopus 로고
    • Growth of Yersinia pseudotuberculosis in mice occurs independently of toll-like receptor 2 expression and induction of interleukin-10
    • DOI 10.1128/IAI.01497-06
    • Auerbuch, V., and Isberg, R.R. (2007). Growth of Yersinia pseudotuberculosis in mice occurs independently of Toll-like receptor 2 expression and induction of interleukin-10. Infect. Immun. 75, 3561-3570. (Pubitemid 47040959)
    • (2007) Infection and Immunity , vol.75 , Issue.7 , pp. 3561-3570
    • Auerbuch, V.1    Isberg, R.R.2
  • 4
    • 77149169405 scopus 로고    scopus 로고
    • Nod2 regulates the host response towards microflora by modulating T cell function and epithelial permeability in mouse Peyer's patches
    • Barreau, F., Madre, C., Meinzer, U., Berrebi, D., Dussaillant, M., Merlin, F., Eckmann, L., Karin, M., Sterkers, G., Bonacorsi, S., et al. (2010). Nod2 regulates the host response towards microflora by modulating T cell function and epithelial permeability in mouse Peyer's patches. Gut 59, 207-217.
    • (2010) Gut , vol.59 , pp. 207-217
    • Barreau, F.1    Madre, C.2    Meinzer, U.3    Berrebi, D.4    Dussaillant, M.5    Merlin, F.6    Eckmann, L.7    Karin, M.8    Sterkers, G.9    Bonacorsi, S.10
  • 5
    • 44949187452 scopus 로고    scopus 로고
    • Reduced secretion of YopJ by Yersinia limits in vivo cell death but enhances bacterial virulence
    • Brodsky, I.E., and Medzhitov, R. (2008). Reduced secretion of YopJ by Yersinia limits in vivo cell death but enhances bacterial virulence. PLoS Pathog. 4, e1000067.
    • (2008) PLoS Pathog. , vol.4
    • Brodsky, I.E.1    Medzhitov, R.2
  • 7
    • 2942535858 scopus 로고    scopus 로고
    • Reciprocal cross-talk between Nod2 and TAK1 signaling pathways
    • DOI 10.1074/jbc.M400682200
    • Chen, C.M., Gong, Y., Zhang, M., and Chen, J.J. (2004). Reciprocal cross-talk between Nod2 and TAK1 signaling pathways. J. Biol. Chem. 279, 25876-25882. (Pubitemid 38756853)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.24 , pp. 25876-25882
    • Chen, C.-M.1    Gong, Y.2    Zhang, M.3    Chen, J.-J.4
  • 9
    • 20444459502 scopus 로고    scopus 로고
    • NOD2 and Crohn's disease: Loss or gain of function?
    • DOI 10.1016/j.immuni.2005.06.004, PII S107476130500169X
    • Eckmann, L., and Karin, M. (2005). NOD2 and Crohn's disease: loss or gain of function? Immunity 22, 661-667. (Pubitemid 40814497)
    • (2005) Immunity , vol.22 , Issue.6 , pp. 661-667
    • Eckmann, L.1    Karin, M.2
  • 11
    • 29144435082 scopus 로고    scopus 로고
    • Yersinia outer protein P suppresses TGF-beta-activated kinase-1 activity to impair innate immune signaling in yersinia enterocolitica-infected cells
    • Haase, R., Richter, K., Pfaffinger, G., Courtois, G., and Ruckdeschel, K. (2005). Yersinia outer protein P suppresses TGF-beta-activated kinase-1 activity to impair innate immune signaling in Yersinia enterocolitica-infected cells. J. Immunol. 175, 8209-8217. (Pubitemid 41798385)
    • (2005) Journal of Immunology , vol.175 , Issue.12 , pp. 8209-8217
    • Haase, R.1    Richter, K.2    Pfaffinger, G.3    Courtois, G.4    Ruckdeschel, K.5
  • 15
    • 79956063855 scopus 로고    scopus 로고
    • Peyer's Patches: The Immune Sensors of the Intestine
    • Published online September 19, 2010. 10.4061/2010/823710
    • Jung, C., Hugot, J.P., and Barreau, F. (2010). Peyer's Patches: The Immune Sensors of the Intestine. Int. J. Inflam. 2010, 823710. Published online September 19, 2010. 10.4061/2010/823710.
    • (2010) Int. J. Inflam. , vol.2010 , pp. 823710
    • Jung, C.1    Hugot, J.P.2    Barreau, F.3
  • 17
    • 84887212416 scopus 로고    scopus 로고
    • Intestinal epithelial-derived TAK1 signaling is essential for cytoprotection against chemical-induced colitis
    • Kim, J.Y., Kajino-Sakamoto, R., Omori, E., Jobin, C., and Ninomiya-Tsuji, J. (2009). Intestinal epithelial-derived TAK1 signaling is essential for cytoprotection against chemical-induced colitis. PLoS ONE 4, e4561.
    • (2009) PLoS ONE , vol.4
    • Kim, J.Y.1    Kajino-Sakamoto, R.2    Omori, E.3    Jobin, C.4    Ninomiya-Tsuji, J.5
  • 21
    • 51949097139 scopus 로고    scopus 로고
    • Caspase-1 activation in macrophages infected with Yersinia pestis KIM requires the type III secretion system effector YopJ
    • Lilo, S., Zheng, Y., and Bliska, J.B. (2008). Caspase-1 activation in macrophages infected with Yersinia pestis KIM requires the type III secretion system effector YopJ. Infect. Immun. 76, 3911-3923.
    • (2008) Infect. Immun. , vol.76 , pp. 3911-3923
    • Lilo, S.1    Zheng, Y.2    Bliska, J.B.3
  • 22
    • 44849136632 scopus 로고    scopus 로고
    • Pannexin-1-mediated intracellular delivery of muramyl dipeptide induces caspase-1 activation via cryopyrin/NLRP3 independently of Nod2
    • Marina-García, N., Franchi, L., Kim, Y.G., Miller, D., McDonald, C., Boons, G.J., and Núñez, G. (2008). Pannexin-1-mediated intracellular delivery of muramyl dipeptide induces caspase-1 activation via cryopyrin/NLRP3 independently of Nod2. J. Immunol. 180, 4050-4057.
    • (2008) J. Immunol. , vol.180 , pp. 4050-4057
    • Marina-García, N.1    Franchi, L.2    Kim, Y.G.3    Miller, D.4    McDonald, C.5    Boons, G.J.6    Núñez, G.7
  • 23
    • 7944232105 scopus 로고    scopus 로고
    • Identification of bacterial muramyl dipeptide as activator of the NALP3/Cryopyrin inflammasome
    • DOI 10.1016/j.cub.2004.10.027, PII S0960982204008309
    • Martinon, F., Agostini, L., Meylan, E., and Tschopp, J. (2004). Identification of bacterial muramyl dipeptide as activator of the NALP3/cryopyrin inflammasome. Curr. Biol. 14, 1929-1934. (Pubitemid 39464816)
    • (2004) Current Biology , vol.14 , Issue.21 , pp. 1929-1934
    • Martinon, F.1    Agostini, L.2    Meylan, E.3    Tschopp, J.4
  • 26
    • 0031744367 scopus 로고    scopus 로고
    • Yersinia-induced apoptosis in vivo aids in the establishment of a systemic infection of mice
    • DOI 10.1084/jem.188.11.2127
    • Monack, D.M., Mecsas, J., Bouley, D., and Falkow, S. (1998). Yersinia-induced apoptosis in vivo aids in the establishment of a systemic infection of mice. J. Exp. Med. 188, 2127-2137. (Pubitemid 28562529)
    • (1998) Journal of Experimental Medicine , vol.188 , Issue.11 , pp. 2127-2137
    • Monack, D.M.1    Mecsas, J.2    Bouley, D.3    Falkow, S.4
  • 27
    • 33744457909 scopus 로고    scopus 로고
    • Yersinia YopJ acetylates and inhibits kinase activation by blocking phosphorylation
    • DOI 10.1126/science.1126867
    • Mukherjee, S., Keitany, G., Li, Y., Wang, Y., Ball, H.L., Goldsmith, E.J., and Orth, K. (2006). Yersinia YopJ acetylates and inhibits kinase activation by blocking phosphorylation. Science 312, 1211-1214. (Pubitemid 43801146)
    • (2006) Science , vol.312 , Issue.5777 , pp. 1211-1214
    • Mukherjee, S.1    Keitany, G.2    Li, Y.3    Wang, Y.4    Ball, H.L.5    Goldsmith, E.J.6    Orth, K.7
  • 31
    • 54949156390 scopus 로고    scopus 로고
    • Yersinia pseudotuberculosis induces transcytosis of nanoparticles across human intestinal villus epithelium via invasin-dependent macropinocytosis
    • Ragnarsson, E.G., Schoultz, I., Gullberg, E., Carlsson, A.H., Tafazoli, F., Lerm, M., Magnusson, K.E., Söderholm, J.D., and Artursson, P. (2008). Yersinia pseudotuberculosis induces transcytosis of nanoparticles across human intestinal villus epithelium via invasin-dependent macropinocytosis. Lab. Invest. 88, 1215-1226.
    • (2008) Lab. Invest. , vol.88 , pp. 1215-1226
    • Ragnarsson, E.G.1    Schoultz, I.2    Gullberg, E.3    Carlsson, A.H.4    Tafazoli, F.5    Lerm, M.6    Magnusson, K.E.7    Söderholm, J.D.8    Artursson, P.9
  • 32
    • 20444478602 scopus 로고    scopus 로고
    • Inflammatory bowel disease associated with Yersinia enterocolitica O:3 infection
    • DOI 10.1016/j.ejim.2004.11.008, PII S0953620505000816
    • Saebo, A., Vik, E., Lange, O.J., and Matuszkiewicz, L. (2005). Inflammatory bowel disease associated with Yersinia enterocolitica O:3 infection. Eur. J. Intern. Med. 16, 176-182. (Pubitemid 40828255)
    • (2005) European Journal of Internal Medicine , vol.16 , Issue.3 , pp. 176-182
    • Saebo, A.1    Vik, E.2    Lange, O.J.3    Matuszkiewicz, L.4
  • 34
    • 0022506170 scopus 로고
    • Acute yersinia infections in man increase intestinal permeability for low-molecular weight polyethylene glycols (PEG 400)
    • Serrander, R., Magnusson, K.E., Kihlström, E., and Sundqvist, T. (1986). Acute yersinia infections in man increase intestinal permeability for low-molecular weight polyethylene glycols (PEG 400). Scand. J. Infect. Dis. 18, 409-413. (Pubitemid 16017367)
    • (1986) Scandinavian Journal of Infectious Diseases , vol.18 , Issue.5 , pp. 409-413
    • Serrander, R.1    Magnusson, K.-E.2    Kihlstrom, E.3    Sundqvist, T.4
  • 36
    • 14844295421 scopus 로고    scopus 로고
    • Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-beta-activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2
    • DOI 10.1074/jbc.M407537200
    • Singhirunnusorn, P., Suzuki, S., Kawasaki, N., Saiki, I., and Sakurai, H. (2005). Critical roles of threonine 187 phosphorylation in cellular stress-induced rapid and transient activation of transforming growth factor-beta-activated kinase 1 (TAK1) in a signaling complex containing TAK1-binding protein TAB1 and TAB2. J. Biol. Chem. 280, 7359-7368. (Pubitemid 40341294)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.8 , pp. 7359-7368
    • Singhirunnusorn, P.1    Suzuki, S.2    Kawasaki, N.3    Saiki, I.4    Sakurai, H.5
  • 38
    • 34848831208 scopus 로고    scopus 로고
    • YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction
    • DOI 10.1111/j.1462-5822.2007.00990.x
    • Sweet, C.R., Conlon, J., Golenbock, D.T., Goguen, J., and Silverman, N. (2007). YopJ targets TRAF proteins to inhibit TLR-mediated NF-kappaB, MAPK and IRF3 signal transduction. Cell. Microbiol. 9, 2700-2715. (Pubitemid 47500520)
    • (2007) Cellular Microbiology , vol.9 , Issue.11 , pp. 2700-2715
    • Sweet, C.R.1    Conlon, J.2    Golenbock, D.T.3    Goguen, J.4    Silverman, N.5
  • 39
    • 0033855909 scopus 로고    scopus 로고
    • Apically exposed, tight junction-associated beta1-integrins allow binding and YopE-mediated perturbation of epithelial barriers by wild-type Yersinia bacteria
    • Tafazoli, F., Holmström, A., Forsberg, A., and Magnusson, K.E. (2000). Apically exposed, tight junction-associated beta1-integrins allow binding and YopE-mediated perturbation of epithelial barriers by wild-type Yersinia bacteria. Infect. Immun. 68, 5335-5343.
    • (2000) Infect. Immun. , vol.68 , pp. 5335-5343
    • Tafazoli, F.1    Holmström, A.2    Forsberg, A.3    Magnusson, K.E.4
  • 41
    • 25444476788 scopus 로고    scopus 로고
    • Yersinia outer proteins: Role in modulation of host cell signaling responses and pathogenesis
    • DOI 10.1146/annurev.micro.59.030804.121320
    • Viboud, G.I., and Bliska, J.B. (2005). Yersinia outer proteins: role in modulation of host cell signaling responses and pathogenesis. Annu. Rev. Microbiol. 59, 69-89. (Pubitemid 41507424)
    • (2005) Annual Review of Microbiology , vol.59 , pp. 69-89
    • Viboud, G.I.1    Bliska, J.B.2
  • 43
    • 34249826059 scopus 로고    scopus 로고
    • Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide
    • DOI 10.1042/BJ20061704
    • Windheim, M., Lang, C., Peggie, M., Plater, L.A., and Cohen, P. (2007). Molecular mechanisms involved in the regulation of cytokine production by muramyl dipeptide. Biochem. J. 404, 179-190. (Pubitemid 46849589)
    • (2007) Biochemical Journal , vol.404 , Issue.2 , pp. 179-190
    • Windheim, M.1    Lang, C.2    Peggie, M.3    Plater, L.A.4    Cohen, P.5
  • 44
    • 54049157903 scopus 로고    scopus 로고
    • Phosphorylation of Thr-178 and Thr-184 in the TAK1 T-loop is required for interleukin (IL)-1-mediated optimal NFkappaB and AP-1 activation as well as IL-6 gene expression
    • Yu, Y., Ge, N., Xie, M., Sun, W., Burlingame, S., Pass, A.K., Nuchtern, J.G., Zhang, D., Fu, S., Schneider, M.D., et al. (2008). Phosphorylation of Thr-178 and Thr-184 in the TAK1 T-loop is required for interleukin (IL)-1-mediated optimal NFkappaB and AP-1 activation as well as IL-6 gene expression. J. Biol. Chem. 283, 24497-24505.
    • (2008) J. Biol. Chem. , vol.283 , pp. 24497-24505
    • Yu, Y.1    Ge, N.2    Xie, M.3    Sun, W.4    Burlingame, S.5    Pass, A.K.6    Nuchtern, J.G.7    Zhang, D.8    Fu, S.9    Schneider, M.D.10
  • 45
    • 77951221762 scopus 로고    scopus 로고
    • YopJ-promoted cytotoxicity and systemic colonization are associated with high levels of murine interleukin-18, gamma interferon, and neutrophils in a live vaccine model of Yersinia pseudotuberculosis infection
    • Zhang, Y., and Bliska, J.B. (2010). YopJ-promoted cytotoxicity and systemic colonization are associated with high levels of murine interleukin-18, gamma interferon, and neutrophils in a live vaccine model of Yersinia pseudotuberculosis infection. Infect. Immun. 78, 2329-2341.
    • (2010) Infect. Immun. , vol.78 , pp. 2329-2341
    • Zhang, Y.1    Bliska, J.B.2
  • 46
    • 79955776183 scopus 로고    scopus 로고
    • A Yersinia effector with enhanced inhibitory activity on the NF-κB pathway activates the NLRP3/ASC/caspase-1 inflammasome in macrophages
    • Zheng, Y., Lilo, S., Brodsky, I.E., Zhang, Y., Medzhitov, R., Marcu, K.B., and Bliska, J.B. (2011). A Yersinia effector with enhanced inhibitory activity on the NF-κB pathway activates the NLRP3/ASC/caspase-1 inflammasome in macrophages. PLoS Pathog. 7, e1002026.
    • (2011) PLoS Pathog. , vol.7
    • Zheng, Y.1    Lilo, S.2    Brodsky, I.E.3    Zhang, Y.4    Medzhitov, R.5    Marcu, K.B.6    Bliska, J.B.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.