-
1
-
-
79955672359
-
Interleukin-6 modifies mRNA expression in mouse skeletal muscle
-
H. Adser, J.F. Wojtaszewski, A.H. Jakobsen, K. Kiilerich, J. Hidalgo, and H. Pilegaard Interleukin-6 modifies mRNA expression in mouse skeletal muscle Acta Physiol. (Oxf.) 202 2011 165 173
-
(2011)
Acta Physiol. (Oxf.)
, vol.202
, pp. 165-173
-
-
Adser, H.1
Wojtaszewski, J.F.2
Jakobsen, A.H.3
Kiilerich, K.4
Hidalgo, J.5
Pilegaard, H.6
-
2
-
-
84899716097
-
Tumor macroenvironment and metabolism
-
W. Al-Zoughbi, J. Huang, G.S. Paramasivan, H. Till, M. Pichler, B. Guertl-Lackner, and G. Hoefler Tumor macroenvironment and metabolism Semin. Oncol. 41 2014 281 295
-
(2014)
Semin. Oncol.
, vol.41
, pp. 281-295
-
-
Al-Zoughbi, W.1
Huang, J.2
Paramasivan, G.S.3
Till, H.4
Pichler, M.5
Guertl-Lackner, B.6
Hoefler, G.7
-
3
-
-
84925844053
-
Time for food: The intimate interplay between nutrition, metabolism, and the circadian clock
-
G. Asher, and P. Sassone-Corsi Time for food: the intimate interplay between nutrition, metabolism, and the circadian clock Cell 161 2015 84 92
-
(2015)
Cell
, vol.161
, pp. 84-92
-
-
Asher, G.1
Sassone-Corsi, P.2
-
4
-
-
84869036539
-
Circadian topology of metabolism
-
J. Bass Circadian topology of metabolism Nature 491 2012 348 356
-
(2012)
Nature
, vol.491
, pp. 348-356
-
-
Bass, J.1
-
5
-
-
79960611800
-
STAT3 activation in skeletal muscle links muscle wasting and the acute phase response in cancer cachexia
-
A. Bonetto, T. Aydogdu, N. Kunzevitzky, D.C. Guttridge, S. Khuri, L.G. Koniaris, and T.A. Zimmers STAT3 activation in skeletal muscle links muscle wasting and the acute phase response in cancer cachexia PLoS ONE 6 2011 e22538
-
(2011)
PLoS ONE
, vol.6
, pp. e22538
-
-
Bonetto, A.1
Aydogdu, T.2
Kunzevitzky, N.3
Guttridge, D.C.4
Khuri, S.5
Koniaris, L.G.6
Zimmers, T.A.7
-
6
-
-
0030941803
-
The SREBP pathway: Regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
-
M.S. Brown, and J.L. Goldstein The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor Cell 89 1997 331 340
-
(1997)
Cell
, vol.89
, pp. 331-340
-
-
Brown, M.S.1
Goldstein, J.L.2
-
7
-
-
33750859187
-
Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase
-
A.L. Carey, G.R. Steinberg, S.L. Macaulay, W.G. Thomas, A.G. Holmes, G. Ramm, O. Prelovsek, C. Hohnen-Behrens, M.J. Watt, D.E. James, and et al. Interleukin-6 increases insulin-stimulated glucose disposal in humans and glucose uptake and fatty acid oxidation in vitro via AMP-activated protein kinase Diabetes 55 2006 2688 2697
-
(2006)
Diabetes
, vol.55
, pp. 2688-2697
-
-
Carey, A.L.1
Steinberg, G.R.2
Macaulay, S.L.3
Thomas, W.G.4
Holmes, A.G.5
Ramm, G.6
Prelovsek, O.7
Hohnen-Behrens, C.8
Watt, M.J.9
James, D.E.10
-
8
-
-
84907223092
-
Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
-
O.R. Colegio, N.Q. Chu, A.L. Szabo, T. Chu, A.M. Rhebergen, V. Jairam, N. Cyrus, C.E. Brokowski, S.C. Eisenbarth, G.M. Phillips, and et al. Functional polarization of tumour-associated macrophages by tumour-derived lactic acid Nature 513 2014 559 563
-
(2014)
Nature
, vol.513
, pp. 559-563
-
-
Colegio, O.R.1
Chu, N.Q.2
Szabo, A.L.3
Chu, T.4
Rhebergen, A.M.5
Jairam, V.6
Cyrus, N.7
Brokowski, C.E.8
Eisenbarth, S.C.9
Phillips, G.M.10
-
9
-
-
0033637383
-
Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus
-
F. Damiola, N. Le Minh, N. Preitner, B. Kornmann, F. Fleury-Olela, and U. Schibler Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus Genes Dev. 14 2000 2950 2961
-
(2000)
Genes Dev.
, vol.14
, pp. 2950-2961
-
-
Damiola, F.1
Le Minh, N.2
Preitner, N.3
Kornmann, B.4
Fleury-Olela, F.5
Schibler, U.6
-
10
-
-
0030840464
-
STATs and gene regulation
-
J.E. Darnell Jr. STATs and gene regulation Science 277 1997 1630 1635
-
(1997)
Science
, vol.277
, pp. 1630-1635
-
-
Darnell, J.E.1
-
11
-
-
0028234529
-
Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins
-
J.E. Darnell Jr., I.M. Kerr, and G.R. Stark Jak-STAT pathways and transcriptional activation in response to IFNs and other extracellular signaling proteins Science 264 1994 1415 1421
-
(1994)
Science
, vol.264
, pp. 1415-1421
-
-
Darnell, J.E.1
Kerr, I.M.2
Stark, G.R.3
-
12
-
-
84883514161
-
Targeting lactate metabolism for cancer therapeutics
-
J.R. Doherty, and J.L. Cleveland Targeting lactate metabolism for cancer therapeutics J. Clin. Invest. 123 2013 3685 3692
-
(2013)
J. Clin. Invest.
, vol.123
, pp. 3685-3692
-
-
Doherty, J.R.1
Cleveland, J.L.2
-
13
-
-
84894590704
-
Reprogramming of the circadian clock by nutritional challenge
-
K.L. Eckel-Mahan, V.R. Patel, S. de Mateo, R. Orozco-Solis, N.J. Ceglia, S. Sahar, S.A. Dilag-Penilla, K.A. Dyar, P. Baldi, and P. Sassone-Corsi Reprogramming of the circadian clock by nutritional challenge Cell 155 2013 1464 1478
-
(2013)
Cell
, vol.155
, pp. 1464-1478
-
-
Eckel-Mahan, K.L.1
Patel, V.R.2
De Mateo, S.3
Orozco-Solis, R.4
Ceglia, N.J.5
Sahar, S.6
Dilag-Penilla, S.A.7
Dyar, K.A.8
Baldi, P.9
Sassone-Corsi, P.10
-
14
-
-
0035930605
-
SOCS-3 inhibits insulin signaling and is up-regulated in response to tumor necrosis factor-alpha in the adipose tissue of obese mice
-
B. Emanuelli, P. Peraldi, C. Filloux, C. Chavey, K. Freidinger, D.J. Hilton, G.S. Hotamisligil, and E. Van Obberghen SOCS-3 inhibits insulin signaling and is up-regulated in response to tumor necrosis factor-alpha in the adipose tissue of obese mice J. Biol. Chem. 276 2001 47944 47949
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 47944-47949
-
-
Emanuelli, B.1
Peraldi, P.2
Filloux, C.3
Chavey, C.4
Freidinger, K.5
Hilton, D.J.6
Hotamisligil, G.S.7
Van Obberghen, E.8
-
15
-
-
68849083050
-
Integrated, nontargeted ultrahigh performance liquid chromatography/electrospray ionization tandem mass spectrometry platform for the identification and relative quantification of the small-molecule complement of biological systems
-
A.M. Evans, C.D. DeHaven, T. Barrett, M. Mitchell, and E. Milgram Integrated, nontargeted ultrahigh performance liquid chromatography/electrospray ionization tandem mass spectrometry platform for the identification and relative quantification of the small-molecule complement of biological systems Anal. Chem. 81 2009 6656 6667
-
(2009)
Anal. Chem.
, vol.81
, pp. 6656-6667
-
-
Evans, A.M.1
DeHaven, C.D.2
Barrett, T.3
Mitchell, M.4
Milgram, E.5
-
16
-
-
23944433875
-
Leukemia inhibitory factor triggers activation of signal transducer and activator of transcription 3, proliferation, invasiveness, and altered protease expression in choriocarcinoma cells
-
J.S. Fitzgerald, S.A. Tsareva, T.G. Poehlmann, L. Berod, A. Meissner, F.M. Corvinus, B. Wiederanders, E. Pfitzner, U.R. Markert, and K. Friedrich Leukemia inhibitory factor triggers activation of signal transducer and activator of transcription 3, proliferation, invasiveness, and altered protease expression in choriocarcinoma cells Int. J. Biochem. Cell Biol. 37 2005 2284 2296
-
(2005)
Int. J. Biochem. Cell Biol.
, vol.37
, pp. 2284-2296
-
-
Fitzgerald, J.S.1
Tsareva, S.A.2
Poehlmann, T.G.3
Berod, L.4
Meissner, A.5
Corvinus, F.M.6
Wiederanders, B.7
Pfitzner, E.8
Markert, U.R.9
Friedrich, K.10
-
17
-
-
0037711399
-
The circadian clock: Pacemaker and tumour suppressor
-
L. Fu, and C.C. Lee The circadian clock: pacemaker and tumour suppressor Nat. Rev. Cancer 3 2003 350 361
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 350-361
-
-
Fu, L.1
Lee, C.C.2
-
19
-
-
36849012237
-
Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas
-
S.P. Gao, K.G. Mark, K. Leslie, W. Pao, N. Motoi, W.L. Gerald, W.D. Travis, W. Bornmann, D. Veach, B. Clarkson, and J.F. Bromberg Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas J. Clin. Invest. 117 2007 3846 3856
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 3846-3856
-
-
Gao, S.P.1
Mark, K.G.2
Leslie, K.3
Pao, W.4
Motoi, N.5
Gerald, W.L.6
Travis, W.D.7
Bornmann, W.8
Veach, D.9
Clarkson, B.10
Bromberg, J.F.11
-
20
-
-
84856019342
-
The nuclear receptor REV-ERBα mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines
-
J.E. Gibbs, J. Blaikley, S. Beesley, L. Matthews, K.D. Simpson, S.H. Boyce, S.N. Farrow, K.J. Else, D. Singh, D.W. Ray, and A.S. Loudon The nuclear receptor REV-ERBα mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines Proc. Natl. Acad. Sci. USA 109 2012 582 587
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 582-587
-
-
Gibbs, J.E.1
Blaikley, J.2
Beesley, S.3
Matthews, L.4
Simpson, K.D.5
Boyce, S.H.6
Farrow, S.N.7
Else, K.J.8
Singh, D.9
Ray, D.W.10
Loudon, A.S.11
-
21
-
-
84897425951
-
Genome-wide analysis of SREBP1 activity around the clock reveals its combined dependency on nutrient and circadian signals
-
F. Gilardi, E. Migliavacca, A. Naldi, M. Baruchet, D. Canella, G. Le Martelot, N. Guex, B. Desvergne CycliX Consortium Genome-wide analysis of SREBP1 activity around the clock reveals its combined dependency on nutrient and circadian signals PLoS Genet. 10 2014 e1004155
-
(2014)
PLoS Genet.
, vol.10
, pp. e1004155
-
-
Gilardi, F.1
Migliavacca, E.2
Naldi, A.3
Baruchet, M.4
Canella, D.5
Le Martelot, G.6
Guex, N.7
Desvergne, B.8
-
22
-
-
58649108302
-
IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer
-
S. Grivennikov, E. Karin, J. Terzic, D. Mucida, G.Y. Yu, S. Vallabhapurapu, J. Scheller, S. Rose-John, H. Cheroutre, L. Eckmann, and M. Karin IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-associated cancer Cancer Cell 15 2009 103 113
-
(2009)
Cancer Cell
, vol.15
, pp. 103-113
-
-
Grivennikov, S.1
Karin, E.2
Terzic, J.3
Mucida, D.4
Yu, G.Y.5
Vallabhapurapu, S.6
Scheller, J.7
Rose-John, S.8
Cheroutre, H.9
Eckmann, L.10
Karin, M.11
-
23
-
-
77950346282
-
Immunity, inflammation, and cancer
-
S.I. Grivennikov, F.R. Greten, and M. Karin Immunity, inflammation, and cancer Cell 140 2010 883 899
-
(2010)
Cell
, vol.140
, pp. 883-899
-
-
Grivennikov, S.I.1
Greten, F.R.2
Karin, M.3
-
24
-
-
0032521284
-
Induction of Jak/STAT signaling by activation of the type 1 TNF receptor
-
D. Guo, J.D. Dunbar, C.H. Yang, L.M. Pfeffer, and D.B. Donner Induction of Jak/STAT signaling by activation of the type 1 TNF receptor J. Immunol. 160 1998 2742 2750
-
(1998)
J. Immunol.
, vol.160
, pp. 2742-2750
-
-
Guo, D.1
Dunbar, J.D.2
Yang, C.H.3
Pfeffer, L.M.4
Donner, D.B.5
-
25
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
D. Hanahan, and R.A. Weinberg Hallmarks of cancer: the next generation Cell 144 2011 646 674
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
26
-
-
84862008430
-
Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet
-
M. Hatori, C. Vollmers, A. Zarrinpar, L. DiTacchio, E.A. Bushong, S. Gill, M. Leblanc, A. Chaix, M. Joens, J.A. Fitzpatrick, and et al. Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet Cell Metab. 15 2012 848 860
-
(2012)
Cell Metab.
, vol.15
, pp. 848-860
-
-
Hatori, M.1
Vollmers, C.2
Zarrinpar, A.3
DiTacchio, L.4
Bushong, E.A.5
Gill, S.6
Leblanc, M.7
Chaix, A.8
Joens, M.9
Fitzpatrick, J.A.10
-
27
-
-
0142027805
-
Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes
-
J.D. Horton, N.A. Shah, J.A. Warrington, N.N. Anderson, S.W. Park, M.S. Brown, and J.L. Goldstein Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes Proc. Natl. Acad. Sci. USA 100 2003 12027 12032
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 12027-12032
-
-
Horton, J.D.1
Shah, N.A.2
Warrington, J.A.3
Anderson, N.N.4
Park, S.W.5
Brown, M.S.6
Goldstein, J.L.7
-
28
-
-
52649107626
-
Cancer cell metabolism: Warburg and beyond
-
P.P. Hsu, and D.M. Sabatini Cancer cell metabolism: Warburg and beyond Cell 134 2008 703 707
-
(2008)
Cell
, vol.134
, pp. 703-707
-
-
Hsu, P.P.1
Sabatini, D.M.2
-
29
-
-
0035893252
-
Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras
-
E.L. Jackson, N. Willis, K. Mercer, R.T. Bronson, D. Crowley, R. Montoya, T. Jacks, and D.A. Tuveson Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras Genes Dev. 15 2001 3243 3248
-
(2001)
Genes Dev.
, vol.15
, pp. 3243-3248
-
-
Jackson, E.L.1
Willis, N.2
Mercer, K.3
Bronson, R.T.4
Crowley, D.5
Montoya, R.6
Jacks, T.7
Tuveson, D.A.8
-
30
-
-
28544432790
-
The differential effects of mutant p53 alleles on advanced murine lung cancer
-
E.L. Jackson, K.P. Olive, D.A. Tuveson, R. Bronson, D. Crowley, M. Brown, and T. Jacks The differential effects of mutant p53 alleles on advanced murine lung cancer Cancer Res. 65 2005 10280 10288
-
(2005)
Cancer Res.
, vol.65
, pp. 10280-10288
-
-
Jackson, E.L.1
Olive, K.P.2
Tuveson, D.A.3
Bronson, R.4
Crowley, D.5
Brown, M.6
Jacks, T.7
-
31
-
-
0035953550
-
Somatic activation of the K-ras oncogene causes early onset lung cancer in mice
-
L. Johnson, K. Mercer, D. Greenbaum, R.T. Bronson, D. Crowley, D.A. Tuveson, and T. Jacks Somatic activation of the K-ras oncogene causes early onset lung cancer in mice Nature 410 2001 1111 1116
-
(2001)
Nature
, vol.410
, pp. 1111-1116
-
-
Johnson, L.1
Mercer, K.2
Greenbaum, D.3
Bronson, R.T.4
Crowley, D.5
Tuveson, D.A.6
Jacks, T.7
-
32
-
-
2942748289
-
AMPK activity is diminished in tissues of IL-6 knockout mice: The effect of exercise
-
M. Kelly, C. Keller, P.R. Avilucea, P. Keller, Z. Luo, X. Xiang, M. Giralt, J. Hidalgo, A.K. Saha, B.K. Pedersen, and N.B. Ruderman AMPK activity is diminished in tissues of IL-6 knockout mice: the effect of exercise Biochem. Biophys. Res. Commun. 320 2004 449 454
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.320
, pp. 449-454
-
-
Kelly, M.1
Keller, C.2
Avilucea, P.R.3
Keller, P.4
Luo, Z.5
Xiang, X.6
Giralt, M.7
Hidalgo, J.8
Saha, A.K.9
Pedersen, B.K.10
Ruderman, N.B.11
-
33
-
-
35548930677
-
High-fat diet disrupts behavioral and molecular circadian rhythms in mice
-
A. Kohsaka, A.D. Laposky, K.M. Ramsey, C. Estrada, C. Joshu, Y. Kobayashi, F.W. Turek, and J. Bass High-fat diet disrupts behavioral and molecular circadian rhythms in mice Cell Metab. 6 2007 414 421
-
(2007)
Cell Metab.
, vol.6
, pp. 414-421
-
-
Kohsaka, A.1
Laposky, A.D.2
Ramsey, K.M.3
Estrada, C.4
Joshu, C.5
Kobayashi, Y.6
Turek, F.W.7
Bass, J.8
-
34
-
-
70349764508
-
REV-ERBalpha participates in circadian SREBP signaling and bile acid homeostasis
-
G. Le Martelot, T. Claudel, D. Gatfield, O. Schaad, B. Kornmann, G. Lo Sasso, A. Moschetta, and U. Schibler REV-ERBalpha participates in circadian SREBP signaling and bile acid homeostasis PLoS Biol. 7 2009 e1000181
-
(2009)
PLoS Biol.
, vol.7
, pp. e1000181
-
-
Le Martelot, G.1
Claudel, T.2
Gatfield, D.3
Schaad, O.4
Kornmann, B.5
Lo Sasso, G.6
Moschetta, A.7
Schibler, U.8
-
35
-
-
79953756112
-
Stat3/Socs3 activation by IL-6 transsignaling promotes progression of pancreatic intraepithelial neoplasia and development of pancreatic cancer
-
M. Lesina, M.U. Kurkowski, K. Ludes, S. Rose-John, M. Treiber, G. Klöppel, A. Yoshimura, W. Reindl, B. Sipos, S. Akira, and et al. Stat3/Socs3 activation by IL-6 transsignaling promotes progression of pancreatic intraepithelial neoplasia and development of pancreatic cancer Cancer Cell 19 2011 456 469
-
(2011)
Cancer Cell
, vol.19
, pp. 456-469
-
-
Lesina, M.1
Kurkowski, M.U.2
Ludes, K.3
Rose-John, S.4
Treiber, M.5
Klöppel, G.6
Yoshimura, A.7
Reindl, W.8
Sipos, B.9
Akira, S.10
-
36
-
-
79953755370
-
AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice
-
Y. Li, S. Xu, M.M. Mihaylova, B. Zheng, X. Hou, B. Jiang, O. Park, Z. Luo, E. Lefai, J.Y. Shyy, and et al. AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice Cell Metab. 13 2011 376 388
-
(2011)
Cell Metab.
, vol.13
, pp. 376-388
-
-
Li, Y.1
Xu, S.2
Mihaylova, M.M.3
Zheng, B.4
Hou, X.5
Jiang, B.6
Park, O.7
Luo, Z.8
Lefai, E.9
Shyy, J.Y.10
-
37
-
-
34248141100
-
A cytokine-mediated link between innate immunity, inflammation, and cancer
-
W.W. Lin, and M. Karin A cytokine-mediated link between innate immunity, inflammation, and cancer J. Clin. Invest. 117 2007 1175 1183
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 1175-1183
-
-
Lin, W.W.1
Karin, M.2
-
38
-
-
51349135630
-
Inflammatory stress exacerbates lipid accumulation in hepatic cells and fatty livers of apolipoprotein E knockout mice
-
K.L. Ma, X.Z. Ruan, S.H. Powis, Y. Chen, J.F. Moorhead, and Z. Varghese Inflammatory stress exacerbates lipid accumulation in hepatic cells and fatty livers of apolipoprotein E knockout mice Hepatology 48 2008 770 781
-
(2008)
Hepatology
, vol.48
, pp. 770-781
-
-
Ma, K.L.1
Ruan, X.Z.2
Powis, S.H.3
Chen, Y.4
Moorhead, J.F.5
Varghese, Z.6
-
39
-
-
77958574512
-
Plasticity and specificity of the circadian epigenome
-
S. Masri, and P. Sassone-Corsi Plasticity and specificity of the circadian epigenome Nat. Neurosci. 13 2010 1324 1329
-
(2010)
Nat. Neurosci.
, vol.13
, pp. 1324-1329
-
-
Masri, S.1
Sassone-Corsi, P.2
-
40
-
-
84905389924
-
Partitioning circadian transcription by SIRT6 leads to segregated control of cellular metabolism
-
S. Masri, P. Rigor, M. Cervantes, N. Ceglia, C. Sebastian, C. Xiao, M. Roqueta-Rivera, C. Deng, T.F. Osborne, R. Mostoslavsky, and et al. Partitioning circadian transcription by SIRT6 leads to segregated control of cellular metabolism Cell 158 2014 659 672
-
(2014)
Cell
, vol.158
, pp. 659-672
-
-
Masri, S.1
Rigor, P.2
Cervantes, M.3
Ceglia, N.4
Sebastian, C.5
Xiao, C.6
Roqueta-Rivera, M.7
Deng, C.8
Osborne, T.F.9
Mostoslavsky, R.10
-
41
-
-
84916882416
-
Circadian clocks, epigenetics, and cancer
-
S. Masri, K. Kinouchi, and P. Sassone-Corsi Circadian clocks, epigenetics, and cancer Curr. Opin. Oncol. 27 2015 50 56
-
(2015)
Curr. Opin. Oncol.
, vol.27
, pp. 50-56
-
-
Masri, S.1
Kinouchi, K.2
Sassone-Corsi, P.3
-
42
-
-
84963952313
-
Versatile functions for IL-6 in metabolism and cancer
-
J. Mauer, J.L. Denson, and J.C. Brüning Versatile functions for IL-6 in metabolism and cancer Trends Immunol. 36 2015 92 101
-
(2015)
Trends Immunol.
, vol.36
, pp. 92-101
-
-
Mauer, J.1
Denson, J.L.2
Brüning, J.C.3
-
43
-
-
3042823539
-
Serum levels of IL-6 and TNF-alpha correlate with clinicopathological features and patient survival in patients with prostate cancer
-
V. Michalaki, K. Syrigos, P. Charles, and J. Waxman Serum levels of IL-6 and TNF-alpha correlate with clinicopathological features and patient survival in patients with prostate cancer Br. J. Cancer 90 2004 2312 2316
-
(2004)
Br. J. Cancer
, vol.90
, pp. 2312-2316
-
-
Michalaki, V.1
Syrigos, K.2
Charles, P.3
Waxman, J.4
-
44
-
-
80052005701
-
Inflammation-associated interleukin-6/signal transducer and activator of transcription 3 activation ameliorates alcoholic and nonalcoholic fatty liver diseases in interleukin-10-deficient mice
-
A.M. Miller, H. Wang, A. Bertola, O. Park, N. Horiguchi, S.H. Ki, S. Yin, F. Lafdil, and B. Gao Inflammation-associated interleukin-6/signal transducer and activator of transcription 3 activation ameliorates alcoholic and nonalcoholic fatty liver diseases in interleukin-10-deficient mice Hepatology 54 2011 846 856
-
(2011)
Hepatology
, vol.54
, pp. 846-856
-
-
Miller, A.M.1
Wang, H.2
Bertola, A.3
Park, O.4
Horiguchi, N.5
Ki, S.H.6
Yin, S.7
Lafdil, F.8
Gao, B.9
-
45
-
-
0034810738
-
Tissue-specific autoregulation of the stat3 gene and its role in interleukin-6-induced survival signals in T cells
-
M. Narimatsu, H. Maeda, S. Itoh, T. Atsumi, T. Ohtani, K. Nishida, M. Itoh, D. Kamimura, S.J. Park, K. Mizuno, and et al. Tissue-specific autoregulation of the stat3 gene and its role in interleukin-6-induced survival signals in T cells Mol. Cell. Biol. 21 2001 6615 6625
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 6615-6625
-
-
Narimatsu, M.1
Maeda, H.2
Itoh, S.3
Atsumi, T.4
Ohtani, T.5
Nishida, K.6
Itoh, M.7
Kamimura, D.8
Park, S.J.9
Mizuno, K.10
-
46
-
-
84925400697
-
Liver inflammation and metabolic signaling in ApcMin/+ mice: The role of cachexia progression
-
A.A. Narsale, R.T. Enos, M.J. Puppa, S. Chatterjee, E.A. Murphy, R. Fayad, M.O. Pena, J.L. Durstine, and J.A. Carson Liver inflammation and metabolic signaling in ApcMin/+ mice: the role of cachexia progression PLoS ONE 10 2015 e0119888
-
(2015)
PLoS ONE
, vol.10
, pp. e0119888
-
-
Narsale, A.A.1
Enos, R.T.2
Puppa, M.J.3
Chatterjee, S.4
Murphy, E.A.5
Fayad, R.6
Pena, M.O.7
Durstine, J.L.8
Carson, J.A.9
-
47
-
-
84961221250
-
The Effect of Sustained Inflammation on Hepatic Mevalonate Pathway Results in Hyperglycemia
-
D. Okin, and R. Medzhitov The Effect of Sustained Inflammation on Hepatic Mevalonate Pathway Results in Hyperglycemia Cell 165 2016 343 356
-
(2016)
Cell
, vol.165
, pp. 343-356
-
-
Okin, D.1
Medzhitov, R.2
-
48
-
-
18444414586
-
Coordinated transcription of key pathways in the mouse by the circadian clock
-
S. Panda, M.P. Antoch, B.H. Miller, A.I. Su, A.B. Schook, M. Straume, P.G. Schultz, S.A. Kay, J.S. Takahashi, and J.B. Hogenesch Coordinated transcription of key pathways in the mouse by the circadian clock Cell 109 2002 307 320
-
(2002)
Cell
, vol.109
, pp. 307-320
-
-
Panda, S.1
Antoch, M.P.2
Miller, B.H.3
Su, A.I.4
Schook, A.B.5
Straume, M.6
Schultz, P.G.7
Kay, S.A.8
Takahashi, J.S.9
Hogenesch, J.B.10
-
50
-
-
33845514595
-
Interleukin-6 regulation of AMP-activated protein kinase. Potential role in the systemic response to exercise and prevention of the metabolic syndrome
-
N.B. Ruderman, C. Keller, A.M. Richard, A.K. Saha, Z. Luo, X. Xiang, M. Giralt, V.B. Ritov, E.V. Menshikova, D.E. Kelley, and et al. Interleukin-6 regulation of AMP-activated protein kinase. Potential role in the systemic response to exercise and prevention of the metabolic syndrome Diabetes 55 Suppl 2 2006 S48 S54
-
(2006)
Diabetes
, vol.55
, pp. S48-S54
-
-
Ruderman, N.B.1
Keller, C.2
Richard, A.M.3
Saha, A.K.4
Luo, Z.5
Xiang, X.6
Giralt, M.7
Ritov, V.B.8
Menshikova, E.V.9
Kelley, D.E.10
-
51
-
-
0036830636
-
SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2
-
L. Rui, M. Yuan, D. Frantz, S. Shoelson, and M.F. White SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2 J. Biol. Chem. 277 2002 42394 42398
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 42394-42398
-
-
Rui, L.1
Yuan, M.2
Frantz, D.3
Shoelson, S.4
White, M.F.5
-
52
-
-
78049503712
-
Liver-specific suppressor of cytokine signaling-3 deletion in mice enhances hepatic insulin sensitivity and lipogenesis resulting in fatty liver and obesity
-
N. Sachithanandan, B.C. Fam, S. Fynch, N. Dzamko, M.J. Watt, S. Wormald, J. Honeyman, S. Galic, J. Proietto, S. Andrikopoulos, and et al. Liver-specific suppressor of cytokine signaling-3 deletion in mice enhances hepatic insulin sensitivity and lipogenesis resulting in fatty liver and obesity Hepatology 52 2010 1632 1642
-
(2010)
Hepatology
, vol.52
, pp. 1632-1642
-
-
Sachithanandan, N.1
Fam, B.C.2
Fynch, S.3
Dzamko, N.4
Watt, M.J.5
Wormald, S.6
Honeyman, J.7
Galic, S.8
Proietto, J.9
Andrikopoulos, S.10
-
53
-
-
70450239457
-
Metabolism and cancer: The circadian clock connection
-
S. Sahar, and P. Sassone-Corsi Metabolism and cancer: the circadian clock connection Nat. Rev. Cancer 9 2009 886 896
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 886-896
-
-
Sahar, S.1
Sassone-Corsi, P.2
-
54
-
-
36849039660
-
IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland
-
P. Sansone, G. Storci, S. Tavolari, T. Guarnieri, C. Giovannini, M. Taffurelli, C. Ceccarelli, D. Santini, P. Paterini, K.B. Marcu, and et al. IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland J. Clin. Invest. 117 2007 3988 4002
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 3988-4002
-
-
Sansone, P.1
Storci, G.2
Tavolari, S.3
Guarnieri, T.4
Giovannini, C.5
Taffurelli, M.6
Ceccarelli, C.7
Santini, D.8
Paterini, P.9
Marcu, K.B.10
-
55
-
-
0037853260
-
Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes
-
J.J. Senn, P.J. Klover, I.A. Nowak, T.A. Zimmers, L.G. Koniaris, R.W. Furlanetto, and R.A. Mooney Suppressor of cytokine signaling-3 (SOCS-3), a potential mediator of interleukin-6-dependent insulin resistance in hepatocytes J. Biol. Chem. 278 2003 13740 13746
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 13740-13746
-
-
Senn, J.J.1
Klover, P.J.2
Nowak, I.A.3
Zimmers, T.A.4
Koniaris, L.G.5
Furlanetto, R.W.6
Mooney, R.A.7
-
56
-
-
0035910387
-
Entrainment of the circadian clock in the liver by feeding
-
K.A. Stokkan, S. Yamazaki, H. Tei, Y. Sakaki, and M. Menaker Entrainment of the circadian clock in the liver by feeding Science 291 2001 490 493
-
(2001)
Science
, vol.291
, pp. 490-493
-
-
Stokkan, K.A.1
Yamazaki, S.2
Tei, H.3
Sakaki, Y.4
Menaker, M.5
-
57
-
-
33846512401
-
The dual function of hepatic SOCS3 in insulin resistance in vivo
-
T. Torisu, N. Sato, D. Yoshiga, T. Kobayashi, T. Yoshioka, H. Mori, M. Iida, and A. Yoshimura The dual function of hepatic SOCS3 in insulin resistance in vivo Genes Cells 12 2007 143 154
-
(2007)
Genes Cells
, vol.12
, pp. 143-154
-
-
Torisu, T.1
Sato, N.2
Yoshiga, D.3
Kobayashi, T.4
Yoshioka, T.5
Mori, H.6
Iida, M.7
Yoshimura, A.8
-
58
-
-
84899747167
-
Depletion of white adipose tissue in cancer cachexia syndrome is associated with inflammatory signaling and disrupted circadian regulation
-
M. Tsoli, M. Schweiger, A.S. Vanniasinghe, A. Painter, R. Zechner, S. Clarke, and G. Robertson Depletion of white adipose tissue in cancer cachexia syndrome is associated with inflammatory signaling and disrupted circadian regulation PLoS ONE 9 2014 e92966
-
(2014)
PLoS ONE
, vol.9
, pp. e92966
-
-
Tsoli, M.1
Schweiger, M.2
Vanniasinghe, A.S.3
Painter, A.4
Zechner, R.5
Clarke, S.6
Robertson, G.7
-
59
-
-
66249108601
-
Understanding the Warburg effect: The metabolic requirements of cell proliferation
-
M.G. Vander Heiden, L.C. Cantley, and C.B. Thompson Understanding the Warburg effect: the metabolic requirements of cell proliferation Science 324 2009 1029 1033
-
(2009)
Science
, vol.324
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
60
-
-
0031009673
-
Contraction-induced changes in acetyl-CoA carboxylase and 5′-AMP-activated kinase in skeletal muscle
-
D. Vavvas, A. Apazidis, A.K. Saha, J. Gamble, A. Patel, B.E. Kemp, L.A. Witters, and N.B. Ruderman Contraction-induced changes in acetyl-CoA carboxylase and 5′-AMP-activated kinase in skeletal muscle J. Biol. Chem. 272 1997 13255 13261
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13255-13261
-
-
Vavvas, D.1
Apazidis, A.2
Saha, A.K.3
Gamble, J.4
Patel, A.5
Kemp, B.E.6
Witters, L.A.7
Ruderman, N.B.8
-
61
-
-
75849136095
-
Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression
-
C. Vollmers, S. Gill, L. DiTacchio, S.R. Pulivarthy, H.D. Le, and S. Panda Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression Proc. Natl. Acad. Sci. USA 106 2009 21453 21458
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 21453-21458
-
-
Vollmers, C.1
Gill, S.2
DiTacchio, L.3
Pulivarthy, S.R.4
Le, H.D.5
Panda, S.6
-
62
-
-
77955150888
-
Blockade of interleukin-6 signaling enhances hepatic steatosis but improves liver injury in methionine choline-deficient diet-fed mice
-
K. Yamaguchi, Y. Itoh, C. Yokomizo, T. Nishimura, T. Niimi, H. Fujii, T. Okanoue, and T. Yoshikawa Blockade of interleukin-6 signaling enhances hepatic steatosis but improves liver injury in methionine choline-deficient diet-fed mice Lab. Invest. 90 2010 1169 1178
-
(2010)
Lab. Invest.
, vol.90
, pp. 1169-1178
-
-
Yamaguchi, K.1
Itoh, Y.2
Yokomizo, C.3
Nishimura, T.4
Niimi, T.5
Fujii, H.6
Okanoue, T.7
Yoshikawa, T.8
-
63
-
-
33746238953
-
Autocrine IL-6-induced Stat3 activation contributes to the pathogenesis of lung adenocarcinoma and malignant pleural effusion
-
H.H. Yeh, W.W. Lai, H.H. Chen, H.S. Liu, and W.C. Su Autocrine IL-6-induced Stat3 activation contributes to the pathogenesis of lung adenocarcinoma and malignant pleural effusion Oncogene 25 2006 4300 4309
-
(2006)
Oncogene
, vol.25
, pp. 4300-4309
-
-
Yeh, H.H.1
Lai, W.W.2
Chen, H.H.3
Liu, H.S.4
Su, W.C.5
-
64
-
-
84908161000
-
Revisiting STAT3 signalling in cancer: New and unexpected biological functions
-
H. Yu, H. Lee, A. Herrmann, R. Buettner, and R. Jove Revisiting STAT3 signalling in cancer: new and unexpected biological functions Nat. Rev. Cancer 14 2014 736 746
-
(2014)
Nat. Rev. Cancer
, vol.14
, pp. 736-746
-
-
Yu, H.1
Lee, H.2
Herrmann, A.3
Buettner, R.4
Jove, R.5
-
65
-
-
77957821693
-
Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis
-
E.E. Zhang, Y. Liu, R. Dentin, P.Y. Pongsawakul, A.C. Liu, T. Hirota, D.A. Nusinow, X. Sun, S. Landais, Y. Kodama, and et al. Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis Nat. Med. 16 2010 1152 1156
-
(2010)
Nat. Med.
, vol.16
, pp. 1152-1156
-
-
Zhang, E.E.1
Liu, Y.2
Dentin, R.3
Pongsawakul, P.Y.4
Liu, A.C.5
Hirota, T.6
Nusinow, D.A.7
Sun, X.8
Landais, S.9
Kodama, Y.10
-
66
-
-
79954452300
-
Inflammatory stress exacerbates hepatic cholesterol accumulation via increasing cholesterol uptake and de novo synthesis
-
L. Zhao, Y. Chen, R. Tang, Y. Chen, Q. Li, J. Gong, A. Huang, Z. Varghese, J.F. Moorhead, and X.Z. Ruan Inflammatory stress exacerbates hepatic cholesterol accumulation via increasing cholesterol uptake and de novo synthesis J. Gastroenterol. Hepatol. 26 2011 875 883
-
(2011)
J. Gastroenterol. Hepatol.
, vol.26
, pp. 875-883
-
-
Zhao, L.1
Chen, Y.2
Tang, R.3
Chen, Y.4
Li, Q.5
Gong, J.6
Huang, A.7
Varghese, Z.8
Moorhead, J.F.9
Ruan, X.Z.10
|