SOCS-3 Inhibits Insulin Signaling and Is Up-regulated in Response to Tumor Necrosis Factor-α in the Adipose Tissue of Obese Mice

Journal of Biological Chemistry

Volumn 276, Issue 51, 2001, Pages 47944-47949

  Emanuelli, Brice ^a   Peraldi, Pascal ^a   Filloux, Chantal ^a   Chavey, Carine ^a   Freidinger, Kathryn ^b   Hilton, Douglas J ^c   Hotamisligil, Gökhan S ^b   Van Obberghen, Emmanuel ^a  

^a INSERM   (France)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c University of Melbourne   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

FEEDBACK; GENES; INSULIN; RNA; TISSUE; TUMORS;

PHOSPHORYLATION;

PROTEINS;

CYTOKINE; INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE 1; MESSENGER RNA; POLYPEPTIDE; PROTEIN; PROTEIN P85; STAT5B PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING 3; TUMOR NECROSIS FACTOR ALPHA; TYROSINE; UNCLASSIFIED DRUG; INSULIN RECEPTOR SUBSTRATE 1 PROTEIN; INSULIN RECEPTOR SUBSTRATE-1 PROTEIN; PHOSPHOPROTEIN; SOCS 3 PROTEIN; SOCS-3 PROTEIN; TUMOR NECROSIS FACTOR;

ADIPOSE TISSUE; ANIMAL CELL; ANIMAL MODEL; ARTICLE; INSULIN RESISTANCE; MOUSE; NEGATIVE FEEDBACK; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; UPREGULATION; WHITE ADIPOSE TISSUE; ANIMAL; CELL STRAIN 3T3; CELL STRAIN COS1; CHEMISTRY; GENETICS; MALE; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY;

ANIMALIA; MUS MUSCULUS;

3T3 CELLS; ADIPOSE TISSUE; ANIMAL; COS CELLS; INSULIN; MALE; MICE; MICE, TRANSGENIC; OBESITY; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TUMOR NECROSIS FACTOR; TYROSINE; UP-REGULATION;

EID: 0035930605     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M104602200     Document Type: Article

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