Estrogen-mediated downregulation of AIRE influences sexual dimorphism in autoimmune diseases

Journal of Clinical Investigation

Volumn 126, Issue 4, 2016, Pages 1525-1537

  Dragin, Nadine ^a,b,c   Bismuth, Jacky ^a,b,c   Cizeron Clairac, Géraldine ^b   Biferi, Maria Grazia ^a,b,c   Berthault, Claire ^d,e   Serraf, Alain ^f   Nottin, Rémi ^f   Klatzmann, David ^g   Cumano, Ana ^d   Barkats, Martine ^a,b,c   Le Panse, Rozen ^a,b,c   Berrih Aknin, Sonia ^a,b,c  

^a SORBONNE UNIVERSITÉ   (France)

^b CNRS   (France)

^c AIM   (France)

^d INSTITUT PASTEUR   (France)

^e UNIVERSITÉ PARIS DESCARTES   (France)

^f CENTRE CHIRURGICAL MARIE LANNELONGUE   (France)

^g PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTANOLONE; AUTOIMMUNE REGULATOR PROTEIN; ESTROGEN; ESTROGEN RECEPTOR ALPHA; GLUTAMATE DECARBOXYLASE 67; MESSENGER RNA; SEX HORMONE; TESTOSTERONE; THYROGLOBULIN; TRANSCRIPTION FACTOR;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; CASTRATION; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CPG ISLAND; DOWN REGULATION; EPITHELIUM CELL; ESTROGEN THERAPY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PUBERTY; SEX DIFFERENCE; THYMUS; THYROIDITIS; ADOLESCENT; ANIMAL; BIOSYNTHESIS; C3H MOUSE; CELL CULTURE; CHILD; DNA METHYLATION; GENE EXPRESSION REGULATION; GENETICS; INFANT; METABOLISM; MIDDLE AGED; PRESCHOOL CHILD; SEXUAL DEVELOPMENT;

ADOLESCENT; ADULT; ANIMALS; AUTOIMMUNE DISEASES; CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; CPG ISLANDS; DNA METHYLATION; ESTROGEN RECEPTOR ALPHA; ESTROGENS; FEMALE; GENE EXPRESSION REGULATION; HUMANS; INFANT; MALE; MICE; MICE, INBRED C3H; MIDDLE AGED; SEX CHARACTERISTICS; THYMUS GLAND; TRANSCRIPTION FACTORS;

EID: 84964618079     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI81894     Document Type: Article

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