Aire-deficient C57BL/6 mice mimicking the common human 13-base pair deletion mutation present with only a mild autoimmune phenotype

Journal of Immunology

Volumn 182, Issue 6, 2009, Pages 3902-3918

  Hubert, François Xavier ^a   Kinkel, Sarah A ^a,b   Crewther, Pauline E ^a   Cannon, Ping Z F ^a   Webster, Kylie E ^a,g   Link, Maire ^c   Uibo, Raivo ^c   O'Bryan, Moira K ^d   Meager, Anthony ^e   Forehan, Simon P ^a   Smyth, Gordon K ^a   Mittaz, Lauréane ^f,h   Antonarakis, Stylianos E ^f   Peterson, Pärt ^c   Heath, William R ^a,b   Scott, Hamish S ^a,b,i,j  

^a WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF TARTU   (Estonia)

^d MONASH UNIVERSITY   (Australia)

^e NATIONAL INSTITUTE FOR BIOLOGICAL STANDARDS AND CONTROL   (United Kingdom)

^f UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^g GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^h LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

ⁱ HANSON INSTITUTE   (Australia)

^j UNIVERSITY OF ADELAIDE   (Australia)

more..

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; AUTOIMMUNE REGULATOR PROTEIN; TRANSCRIPTION FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; AUTOIMMUNE POLYENDOCRINOPATHY CANDIDIASIS ECTODERMAL DYSTROPHY; AUTOIMMUNITY; BASE PAIRING; CANDIDA ALBICANS; CANDIDIASIS; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL COMPARTMENTALIZATION; CONTROLLED STUDY; DELETION MUTANT; DISEASE PREDISPOSITION; DISEASE SEVERITY; EXON; FEMALE; GENE DELETION; GENE MUTATION; HISTOLOGY; INFECTION CONTROL; LYMPHOCYTIC INFILTRATION; MALE; MALE INFERTILITY; MOUSE; MOUTH INFECTION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; QUALITY OF LIFE; SPLEEN; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; THYMUS; WILD TYPE; AMINO ACID SEQUENCE; ANIMAL; AUTOIMMUNE POLYENDOCRINOPATHY; BIOSYNTHESIS; C57BL MOUSE; CBA MOUSE; CELL LINE; DISEASE MODEL; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; MOLECULAR MIMICRY; MOUSE MUTANT; NUCLEOTIDE SEQUENCE; PATHOLOGY; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; BASE PAIRING; BASE SEQUENCE; CELL LINE; DISEASE MODELS, ANIMAL; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, KNOCKOUT; MOLECULAR MIMICRY; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PHENOTYPE; POLYENDOCRINOPATHIES, AUTOIMMUNE; SEQUENCE HOMOLOGY, AMINO ACID; THYMUS GLAND; TRANSCRIPTION FACTORS;

EID: 65449133931     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0802124     Document Type: Article

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