Decreased AIRE expression and global thymic hypofunction in Down syndrome

Journal of Immunology

Volumn 187, Issue 6, 2011, Pages 3422-3430

  Lima, Flavia A ^a   Moreira Filho, Carlos A ^a   Ramos, Patrícia L ^a   Brentani, Helena ^a   Lima, Leandro De A ^b   Arrais, Magaly ^c   Bento De Souza, Luiz C ^c   Bento De Souza, Luciana ^c   Duarte, Maria I ^a   Coutinho, Antonio ^d   Carneiro Sampaio, Magda ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b A C CAMARGO CANCER CENTER   (Brazil)

^c Hospital do Coracao   (Brazil)

^d INSTITUTO GULBENKIAN DE CIÊNCIA   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOIMMUNE REGULATOR PROTEIN; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTOME;

AIRE GENE; ANTIGEN PRESENTATION; ARTICLE; CD1A GENE; CD1BA GENE; CD1C GENE; CD3D GENE; CD3E GENE; CD74 GENE; CDK6 GENE; CELL DIVISION; CHILD; CLINICAL ARTICLE; CONGENITAL HEART DISEASE; CONTROLLED STUDY; DNA MICROARRAY; DOWN SYNDROME; ERAP GENE; GENE; GENE EXPRESSION; GLOBAL THYMIC HYPOFUNCTION; HLA DQB1 GENE; HLA DRB3 GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; IL2RG GENE; IMMUNE RESPONSE; IMMUNITY; IMMUNOHISTOCHEMISTRY; INFANT; LAMNB1 GENE; LYMPHOCYTE DIFFERENTIATION; NUCLEOTIDE SEQUENCE; NUP93 GENE; PRDX2 GENE; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAG2 GENE; REAL TIME POLYMERASE CHAIN REACTION; SCHOOL CHILD; SH2D1A GENE; T LYMPHOCYTE; THYMUS DISEASE; TOP2A GENE;

CHILD; CHILD, PRESCHOOL; DOWN SYNDROME; DOWN-REGULATION; FEMALE; GENE EXPRESSION PROFILING; HUMANS; IMMUNOHISTOCHEMISTRY; INFANT; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; THYMUS GLAND; TRANSCRIPTION FACTORS;

EID: 80053082182     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1003053     Document Type: Article

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