Lipopolysaccharides may aggravate apoptosis through accumulation of autophagosomes in alveolar macrophages of human silicosis

Autophagy

Volumn 11, Issue 12, 2015, Pages 2346-2357

  Chen, Shi ^a,b   Yuan, Juxiang ^b   Yao, Sanqiao ^c   Jin, Yulan ^b   Chen, Gang ^d   Tian, Wei ^b   Xi, Jinkun ^b   Xu, Zhelong ^b   Weng, Dong ^a   Chen, Jie ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b NORTH CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c XINXIANG MEDICAL UNIVERSITY   (China)

^d Beidaihe Sanitarium for China Coal Miners ^*  (China)

Author keywords

Alveolar macrophages; Apoptosis; Autophagic degradation; Autophagosome; Autophagy; LPS; Lysosome; Silicosis; TLR4

Indexed keywords

3 METHYLADENINE; BECLIN 1; LIPOPOLYSACCHARIDE; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; MAMMALIAN TARGET OF RAPAMYCIN; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN P62; SILICON DIOXIDE; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; APOPTOSIS REGULATORY PROTEIN; CASPASE 3;

ADULT; APOPTOSIS; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CONTROLLED STUDY; DISEASE COURSE; HUMAN; HUMAN CELL; LUNG ALVEOLUS MACROPHAGE; LYSOSOME; MAJOR CLINICAL STUDY; MALE; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SILICOSIS; STIMULATION; CELL LINE; DRUG EFFECTS; MACROPHAGE; METABOLISM;

APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CASPASE 3; CELL LINE; HUMANS; LIPOPOLYSACCHARIDES; LYSOSOMES; MACROPHAGES; MACROPHAGES, ALVEOLAR; SILICOSIS;

EID: 84964206611     PISSN: 15548627     EISSN: 15548635     Source Type: Journal    
DOI: 10.1080/15548627.2015.1109765     Document Type: Article

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