-
1
-
-
0033679897
-
Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans
-
Date Y, Kojima M, Hosoda H, et al. Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans. Endocrinology. 2000;141(11):4255-4261
-
(2000)
Endocrinology.
, vol.141
, Issue.11
, pp. 4255-4261
-
-
Date, Y.1
Kojima, M.2
Hosoda, H.3
-
2
-
-
3042735648
-
The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans
-
Gnanapavan S, Kola B, Bustin SA, et al. The tissue distribution of the mRNA of ghrelin and subtypes of its receptor, GHS-R, in humans. J Clin Endocrinol Metab. 2002;87(6):2988
-
(2002)
J Clin Endocrinol Metab.
, vol.87
, Issue.6
, pp. 2988
-
-
Gnanapavan, S.1
Kola, B.2
Bustin, S.A.3
-
3
-
-
70449433040
-
A concerted kinase interplay identifies PPAR+ as a molecular target of ghrelin signaling in macrophages
-
Demers A, Caron V, Rodrigue-Way A, Wahli W, Ong H, Tremblay A. A concerted kinase interplay identifies PPAR+ as a molecular target of ghrelin signaling in macrophages. PloS One. 2009;4(11): E7728
-
(2009)
PloS One.
, vol.4
, Issue.11
, pp. e7728
-
-
Demers, A.1
Caron, V.2
Rodrigue-Way, A.3
Wahli, W.4
Ong, H.5
Tremblay, A.6
-
4
-
-
33846435771
-
Acylated and unacylated ghrelin promote proliferation and inhibit apoptosis of pancreatic ß-cells and human islets: Involvement of 3,5-cyclic adenosine monophosphate/protein kinase A, extracellular signal-regulated kinase 1/2, and phosphatidyl inositol 3-kinase/Akt signaling
-
Granata R, Settanni F, Biancone L, et al. Acylated and unacylated ghrelin promote proliferation and inhibit apoptosis of pancreatic ß-cells and human islets: Involvement of 3,5-cyclic adenosine monophosphate/protein kinase A, extracellular signal-regulated kinase 1/2, and phosphatidyl inositol 3-kinase/Akt signaling. Endocrinology. 2007;148(2):512-529
-
(2007)
Endocrinology.
, vol.148
, Issue.2
, pp. 512-529
-
-
Granata, R.1
Settanni, F.2
Biancone, L.3
-
5
-
-
0037164747
-
Ghrelin and des-Acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT
-
Baldanzi G, Filigheddu N, Cutrupi S, et al. Ghrelin and des-Acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT. J Cell Biol. 2002;159(6): 1029-1037
-
(2002)
J Cell Biol.
, vol.159
, Issue.6
, pp. 1029-1037
-
-
Baldanzi, G.1
Filigheddu, N.2
Cutrupi, S.3
-
6
-
-
61549095546
-
Ghrelin antagonized 1-methyl-4-phenylpyridinium [MPP(+)]-induced apoptosis in MES23.5 cells
-
Dong J, Song N, Xie J, Jiang H. Ghrelin antagonized 1-methyl-4-phenylpyridinium [MPP(+)]-induced apoptosis in MES23.5 cells. J Mol Neurosci. 2009;37(2):182-189
-
(2009)
J Mol Neurosci.
, vol.37
, Issue.2
, pp. 182-189
-
-
Dong, J.1
Song, N.2
Xie, J.3
Jiang, H.4
-
7
-
-
67349227911
-
Ghrelin inhibits apoptosis induced by high glucose and sodium palmitate in adult rat cardiomyocytes through the PI3K-Akt signaling pathway
-
Kui L, Weiwei Z, Ling L, et al. Ghrelin inhibits apoptosis induced by high glucose and sodium palmitate in adult rat cardiomyocytes through the PI3K-Akt signaling pathway. Regul Pept. 2009;155 (1-3):62-69
-
(2009)
Regul Pept.
, vol.155
, Issue.1-3
, pp. 62-69
-
-
Kui, L.1
Weiwei, Z.2
Ling, L.3
-
8
-
-
34548427342
-
Effect of ghrelin onhumanendothelial cells apoptosis induced by high glucose
-
ZhaoH, Liu G,WangQ, et al. Effect of ghrelin onhumanendothelial cells apoptosis induced by high glucose. Biochem Biophys Res Commun. 2007;362(3):677-681
-
(2007)
Biochem Biophys Res Commun.
, vol.362
, Issue.3
, pp. 677-681
-
-
Zhao, H.1
Liu, G.2
Wang, Q.3
-
9
-
-
34447290269
-
Ghrelin inhibit cell apoptosis in pancreatic ß cell line HIT-T15 via mitogen-Activated protein kinase/ phosphoinositide 3-kinase pathways
-
Zhang Y, Ying B, Shi L, et al. Ghrelin inhibit cell apoptosis in pancreatic ß cell line HIT-T15 via mitogen-Activated protein kinase/ phosphoinositide 3-kinase pathways. Toxicology. 2007;237(1-3): 194-202
-
(2007)
Toxicology.
, vol.237
, Issue.1-3
, pp. 194-202
-
-
Zhang, Y.1
Ying, B.2
Shi, L.3
-
10
-
-
23844447768
-
Ghrelin stimulates proliferation and differentiation and inhibits apoptosis in osteoblastic MC3T3-E1 cells
-
Kim SW, Her SJ, Park SJ, et al. Ghrelin stimulates proliferation and differentiation and inhibits apoptosis in osteoblastic MC3T3-E1 cells. Bone. 2005;37(3):359-369
-
(2005)
Bone.
, vol.37
, Issue.3
, pp. 359-369
-
-
Kim, S.W.1
Her, S.J.2
Park, S.J.3
-
11
-
-
37549043548
-
Suppression of intestinal mucosal apoptosis by ghrelin in fasting rats
-
Park JM, Kakimoto T, Kuroki T, et al. Suppression of intestinal mucosal apoptosis by ghrelin in fasting rats. Exp Biol Med. 2008; 233(1):48-56
-
(2008)
Exp Biol Med.
, vol.233
, Issue.1
, pp. 48-56
-
-
Park, J.M.1
Kakimoto, T.2
Kuroki, T.3
-
12
-
-
54749146658
-
Inhibition of proliferation and apoptosis of vascular smooth muscle cells by ghrelin
-
Zhan M, Yuan F, Liu H, Chen H, Qiu X, Fang W. Inhibition of proliferation and apoptosis of vascular smooth muscle cells by ghrelin. Acta Biochim Biophys Sinica. 2008;40(9):769-776
-
(2008)
Acta Biochim Biophys Sinica.
, vol.40
, Issue.9
, pp. 769-776
-
-
Zhan, M.1
Yuan, F.2
Liu, H.3
Chen, H.4
Qiu, X.5
Fang, W.6
-
13
-
-
35448941488
-
Role of oxidants in lung injury during sepsis
-
Guo RF, Ward PA. Role of oxidants in lung injury during sepsis. Antioxidants Redox Signaling. 2007;9(11):1991-2002
-
(2007)
Antioxidants Redox Signaling.
, vol.9
, Issue.11
, pp. 1991-2002
-
-
Guo, R.F.1
Ward, P.A.2
-
14
-
-
26244446442
-
Acute lung injury and the acute respiratory distress syndrome: Four decades of inquiry into pathogenesis and rational management
-
Matthay MA, Zimmerman GA. Acute lung injury and the acute respiratory distress syndrome: four decades of inquiry into pathogenesis and rational management. Am J Resp Cell Mol Biol. 2005; 33(4):319-327
-
(2005)
Am J Resp Cell Mol Biol.
, vol.33
, Issue.4
, pp. 319-327
-
-
Matthay, M.A.1
Zimmerman, G.A.2
-
15
-
-
0028300085
-
Report of the American-European Consensus Conference on ARDS: Definitions, mechanisms, relevant outcomes and clinical trial coordination
-
The Consensus Committee
-
Bernard GR, Artigas A, Brigham KL, et al. Report of the American-European Consensus Conference on ARDS: Definitions, mechanisms, relevant outcomes and clinical trial coordination. The Consensus Committee. Intens Care Med. 1994;20(3):225-232
-
(1994)
Intens Care Med.
, vol.20
, Issue.3
, pp. 225-232
-
-
Bernard, G.R.1
Artigas, A.2
Brigham, K.L.3
-
16
-
-
44449162461
-
Alveolar macrophage suppression in sepsis is associated with high mobility group box 1 transmigration
-
Pahuja M, Tran C, Wang H, Yin K. Alveolar macrophage suppression in sepsis is associated with high mobility group box 1 transmigration. Shock. 2008;29(6):754-760
-
(2008)
Shock.
, vol.29
, Issue.6
, pp. 754-760
-
-
Pahuja, M.1
Tran, C.2
Wang, H.3
Yin, K.4
-
17
-
-
0035998398
-
Apoptosis contributes to the decrement in numbers of alveolar macrophages from rats with polymicrobial sepsis
-
Lu MC, Liu TA, Lee MR, Lin L, Chang WC. Apoptosis contributes to the decrement in numbers of alveolar macrophages from rats with polymicrobial sepsis. J Microbiol Immunol Infect. 2002; 35(2):71-77
-
(2002)
J Microbiol Immunol Infect.
, vol.35
, Issue.2
, pp. 71-77
-
-
Lu, M.C.1
Liu, T.A.2
Lee, M.R.3
Lin, L.4
Chang, W.C.5
-
18
-
-
84879053288
-
Comparative analysis of the alveolar macrophage proteome in ALI/ARDS patients between the exudative phase and recovery phase
-
Dong HY, Li JX, Lv YD, et al. Comparative analysis of the alveolar macrophage proteome in ALI/ARDS patients between the exudative phase and recovery phase. BMC Immunol. 2013;14:25
-
(2013)
BMC Immunol.
, vol.14
, pp. 25
-
-
Dong, H.Y.1
Li, J.X.2
Lv, Y.D.3
-
19
-
-
84897069139
-
Alveolar macrophage depletion increases the severity of acute inflammation following nonlethal unilateral lung contusion in mice
-
Machado-Aranda D, V Suresh M, Yu B, Dolgachev V, Hemmila MR,Raghavendran K. Alveolar macrophage depletion increases the severity of acute inflammation following nonlethal unilateral lung contusion in mice. J Trauma Acute Care Surg. 2014;76(4):982-990
-
(2014)
J Trauma Acute Care Surg.
, vol.76
, Issue.4
, pp. 982-990
-
-
Machado-Aranda, D.1
Suresh, M.V.2
Yu, B.3
Dolgachev, V.4
Hemmila, M.R.5
Raghavendran, K.6
-
20
-
-
84893213346
-
The NLRP3 inflammasome is required for the development of hypoxemia in LPS/mechanical ventilation acute lung injury
-
Jones HD, Crother TR, Gonzalez-Villalobos RA, et al. The NLRP3 inflammasome is required for the development of hypoxemia in LPS/mechanical ventilation acute lung injury. Am J Resp Cell Mol Biol. 2014;50(2):270-280
-
(2014)
Am J Resp Cell Mol Biol.
, vol.50
, Issue.2
, pp. 270-280
-
-
Jones, H.D.1
Crother, T.R.2
Gonzalez-Villalobos, R.A.3
-
21
-
-
84872855585
-
Cardioprotective effect of ghrelin in cardiopulmonary bypass involves a reduction in inflammatory response
-
Cao Y, Tang J, Yang T, et al. Cardioprotective effect of ghrelin in cardiopulmonary bypass involves a reduction in inflammatory response. PloS One. 2013;8(1):e55021
-
(2013)
PloS One.
, vol.8
, Issue.1
, pp. e55021
-
-
Cao, Y.1
Tang, J.2
Yang, T.3
-
22
-
-
84888201169
-
Ghrelin inhibits high glucose-induced PC12 cell apoptosis by regulating TLR4/NF-κB pathway
-
Liu X, Xiao Q, Zhao K, Gao Y. Ghrelin inhibits high glucose-induced PC12 cell apoptosis by regulating TLR4/NF-κB pathway. Inflammation. 2013;36(6):1286-1294
-
(2013)
Inflammation.
, vol.36
, Issue.6
, pp. 1286-1294
-
-
Liu, X.1
Xiao, Q.2
Zhao, K.3
Gao, Y.4
-
23
-
-
39149099430
-
Exogenous ghrelin modulates release of pro-inflammatory and anti-inflammatory cytokines in LPS-stimulated macrophages through distinct signaling pathways
-
Waseem T, Duxbury M, Ito H, Ashley SW, Robinson MK. Exogenous ghrelin modulates release of pro-inflammatory and anti-inflammatory cytokines in LPS-stimulated macrophages through distinct signaling pathways. Surgery. 2008;143(3):334-342
-
(2008)
Surgery.
, vol.143
, Issue.3
, pp. 334-342
-
-
Waseem, T.1
Duxbury, M.2
Ito, H.3
Ashley, S.W.4
Robinson, M.K.5
-
24
-
-
81255127597
-
Ghrelin ameliorates bleomycininduced acute lung injury by protecting alveolar epithelial cells and suppressing lung inflammation
-
Imazu Y, Yanagi S, Miyoshi K, et al. Ghrelin ameliorates bleomycininduced acute lung injury by protecting alveolar epithelial cells and suppressing lung inflammation. Eur J Pharmacol. 2011;672(1-3): 153-158
-
(2011)
Eur J Pharmacol.
, vol.672
, Issue.1-3
, pp. 153-158
-
-
Imazu, Y.1
Yanagi, S.2
Miyoshi, K.3
-
25
-
-
35348960888
-
Ghrelin attenuates sepsis-induced acute lung injury and mortality in rats
-
Wu R, Dong W, Zhou M, et al. Ghrelin attenuates sepsis-induced acute lung injury and mortality in rats. Am J Resp Crit Care Med. 2007;176(8):805-813
-
(2007)
Am J Resp Crit Care Med.
, vol.176
, Issue.8
, pp. 805-813
-
-
Wu, R.1
Dong, W.2
Zhou, M.3
-
26
-
-
80053295242
-
Voluntary exercise attenuates obesity-Associated inflammation through ghrelin expressed in macrophages
-
Kizaki T, Maegawa T, Sakurai T, et al. Voluntary exercise attenuates obesity-Associated inflammation through ghrelin expressed in macrophages. Biochem Biophys Res Commun. 2011;413(3):454-459
-
(2011)
Biochem Biophys Res Commun.
, vol.413
, Issue.3
, pp. 454-459
-
-
Kizaki, T.1
Maegawa, T.2
Sakurai, T.3
-
27
-
-
16844387124
-
Role of JNK activation in apoptosis: A double-edged sword
-
Liu J, Lin AN. Role of JNK activation in apoptosis: A double-edged sword. Cell Res. 2005;15(1):36-42
-
(2005)
Cell Res.
, vol.15
, Issue.1
, pp. 36-42
-
-
Liu, J.1
Lin, A.N.2
-
28
-
-
0035825119
-
Wnt-1 signaling inhibits apoptosis by activating ß-catenin/T cell factor-mediated transcription
-
Chen S, Guttridge DC, You Z, et al. Wnt-1 signaling inhibits apoptosis by activating ß-catenin/T cell factor-mediated transcription. J Cell Biol. 2001;152(1):87-96
-
(2001)
J Cell Biol.
, vol.152
, Issue.1
, pp. 87-96
-
-
Chen, S.1
Guttridge, D.C.2
You, Z.3
-
30
-
-
77952576252
-
Ghrelin attenuates kainic acidinduced neuronal cell death in the mouse hippocampus
-
Lee J, Lim E, Kim Y, Li E, Park S. Ghrelin attenuates kainic acidinduced neuronal cell death in the mouse hippocampus. J Endocrinol. 2010;205(3):263-270
-
(2012)
J Endocrinol.
, vol.205
, Issue.3
, pp. 263-270
-
-
Lee, J.1
Lim, E.2
Kim, Y.3
Li, E.4
Park, S.5
-
31
-
-
41149108113
-
Gastric motor effects of ghrelin and growth hormone releasing peptide 6 in diabetic mice with gastroparesis
-
Qiu WC, Wang ZG, Wang WG, Yan J, Zheng Q. Gastric motor effects of ghrelin and growth hormone releasing peptide 6 in diabetic mice with gastroparesis. World J Gastroenterol. 2008;14(9):1419-1424
-
(2008)
World J Gastroenterol.
, vol.14
, Issue.9
, pp. 1419-1424
-
-
Qiu, W.C.1
Wang, Z.G.2
Wang, W.G.3
Yan, J.4
Zheng, Q.5
-
32
-
-
63449106102
-
Selective serotonin reuptake inhibitors modify physiological gastrointestinal motor activities via 5-HT2c receptor and acyl ghrelin
-
Fujitsuka N, Asakawa A, Hayashi M, et al. Selective serotonin reuptake inhibitors modify physiological gastrointestinal motor activities via 5-HT2c receptor and acyl ghrelin. Biol Psychiatry. 2009; 65(9):748-759
-
(2009)
Biol Psychiatry.
, vol.65
, Issue.9
, pp. 748-759
-
-
Fujitsuka, N.1
Asakawa, A.2
Hayashi, M.3
-
33
-
-
57449085103
-
Losartan, an antagonist of AT1 receptor for angiotensin II, attenuates lipopolysaccharide-induced acute lung injury in rat
-
Liu L, Qiu HB, Yang Y, Wang L, Ding HM, Li HP. Losartan, an antagonist of AT1 receptor for angiotensin II, attenuates lipopolysaccharide-induced acute lung injury in rat. Arch Biochem Biophys. 2009;481(1):131-136
-
(2009)
Arch Biochem Biophys.
, vol.481
, Issue.1
, pp. 131-136
-
-
Liu, L.1
Qiu, H.B.2
Yang, Y.3
Wang, L.4
Ding, H.M.5
Li, H.P.6
-
34
-
-
0035109852
-
Neutrophil activation and acute lung injury
-
Lee WL, Downey GP. Neutrophil activation and acute lung injury. Curr Opin Crit Care. 2001;7(1):1-7
-
(2001)
Curr Opin Crit Care.
, vol.7
, Issue.1
, pp. 1-7
-
-
Lee, W.L.1
Downey, G.P.2
-
35
-
-
0035865463
-
Surfactant protein A enhances alveolar macrophage phagocytosis of apoptotic neutrophils
-
Schagat TL, Wofford JA, Wright JR. Surfactant protein A enhances alveolar macrophage phagocytosis of apoptotic neutrophils. J Immunol. 2001;166(4):2727-2733
-
(2001)
J Immunol.
, vol.166
, Issue.4
, pp. 2727-2733
-
-
Schagat, T.L.1
Wofford, J.A.2
Wright, J.R.3
-
36
-
-
0037224290
-
Fourteen-member macrolides promote the phosphatidylserine receptor-dependent phagocytosis of apoptotic neutrophils by alveolar macrophages
-
Yamaryo T, Oishi K, Yoshimine H, Tsuchihashi Y, Matsushima K, Nagatake T. Fourteen-member macrolides promote the phosphatidylserine receptor-dependent phagocytosis of apoptotic neutrophils by alveolar macrophages. Antimicrobial Agents Chemother. 2003; 47(1):48-53
-
(2003)
Antimicrobial Agents Chemother.
, vol.47
, Issue.1
, pp. 48-53
-
-
Yamaryo, T.1
Oishi, K.2
Yoshimine, H.3
Tsuchihashi, Y.4
Matsushima, K.5
Nagatake, T.6
-
37
-
-
84866295321
-
Resolvin E1 promotes phagocytosis-induced neutrophil apoptosis and accelerates resolution of pulmonary inflammation
-
El Kebir D, Gjorstrup P, Filep JG. Resolvin E1 promotes phagocytosis-induced neutrophil apoptosis and accelerates resolution of pulmonary inflammation. Proc Natl Acad Sci USA. 2012;109(37): 14983-14988
-
(2012)
Proc Natl Acad Sci USA.
, vol.109
, Issue.37
, pp. 14983-14988
-
-
El Kebir, D.1
Gjorstrup, P.2
Filep, J.G.3
-
38
-
-
38049123476
-
Clearance of apoptotic cells by phagocytes
-
Erwig LP, Henson PM. Clearance of apoptotic cells by phagocytes. Cell Death Differ. 2008;15(2):243-250
-
(2008)
Cell Death Differ.
, vol.15
, Issue.2
, pp. 243-250
-
-
Erwig, L.P.1
Henson, P.M.2
-
39
-
-
0035172366
-
Sepsis-induced immunosuppression: From bad to worse
-
Reddy RC, Chen GH, Tekchandani PK, Standiford TJ. Sepsis-induced immunosuppression: from bad to worse. Immunol Res. 2001; 24(3):273-287
-
(2001)
Immunol Res.
, vol.24
, Issue.3
, pp. 273-287
-
-
Reddy, R.C.1
Chen, G.H.2
Tekchandani, P.K.3
Standiford, T.J.4
-
40
-
-
0032933560
-
IL-10 is a major mediator of sepsis-induced impairment in lung antibacterial host defense
-
Steinhauser ME, Hogaboam GM, Kunkel SL, Lukacs NW, Strieter RM, Standiford TJ. IL-10 is a major mediator of sepsis-induced impairment in lung antibacterial host defense. J Immunol. 1999; 162(1):392-399
-
(1999)
J Immunol.
, vol.162
, Issue.1
, pp. 392-399
-
-
Steinhauser, M.E.1
Hogaboam, G.M.2
Kunkel, S.L.3
Lukacs, N.W.4
Strieter, R.M.5
Standiford, T.J.6
-
41
-
-
33748317968
-
Sepsis-induced suppression of lung innate immunity is mediated by IRAK-M
-
Deng JC, Cheng GH, Newstead MW, et al. Sepsis-induced suppression of lung innate immunity is mediated by IRAK-M. J Clin Invest. 2006;116(9):2532-2542
-
(2006)
J Clin Invest.
, vol.116
, Issue.9
, pp. 2532-2542
-
-
Deng, J.C.1
Cheng, G.H.2
Newstead, M.W.3
-
42
-
-
0031004806
-
Alveolar macrophages are required for protective pulmonary defenses in murine Klebsiella pneumonia: Elimination of alveolar macrophages increases neutrophil recruitment but decreases bacterial clearance and survival
-
Broug-Holub E, Toews GB, van Iwaarden JF, et al. Alveolar macrophages are required for protective pulmonary defenses in murine Klebsiella pneumonia: Elimination of alveolar macrophages increases neutrophil recruitment but decreases bacterial clearance and survival. Infect Immun. 1997;65(4):1139-1146
-
(1997)
Infect Immun.
, vol.65
, Issue.4
, pp. 1139-1146
-
-
Broug-Holub, E.1
Toews, G.B.2
Van Iwaarden, J.F.3
-
43
-
-
84871061105
-
Modulation of macrophage efferocytosis in inflammation
-
Korns D, Frasch SC, Fernandez-Boyanapalli R, Henson PM, Bratton DL. Modulation of macrophage efferocytosis in inflammation. Front Immunol. 2011;2:57
-
(2011)
Front Immunol.
, vol.2
, pp. 57
-
-
Korns, D.1
Frasch, S.C.2
Fernandez-Boyanapalli, R.3
Henson, P.M.4
Bratton, D.L.5
-
44
-
-
48349103039
-
Ghrelin attenuates lipopolysaccharide-induced acute lung injury through no pathway
-
Chen J, Liu XJ, Shuo QL, Li SQ, Luo FM. Ghrelin attenuates lipopolysaccharide-induced acute lung injury through no pathway. Med Sci Monitor. 2008;14(7):Br141-Br146
-
(2008)
Med Sci Monitor.
, vol.14
, Issue.7
, pp. Br141-Br146
-
-
Chen, J.1
Liu, X.J.2
Shuo, Q.L.3
Li, S.Q.4
Luo, F.M.5
-
45
-
-
37549060716
-
Exogenous ghrelin attenuates the progression of chronic hypoxia-induced pulmonary hypertension in conscious rats
-
Schwenke DO, Tokudome T, Shirai M, et al. Exogenous ghrelin attenuates the progression of chronic hypoxia-induced pulmonary hypertension in conscious rats. Endocrinology. 2008;149(1):237-244
-
(2008)
Endocrinology.
, vol.149
, Issue.1
, pp. 237-244
-
-
Schwenke, D.O.1
Tokudome, T.2
Shirai, M.3
-
46
-
-
0033120115
-
Overexpression of Bcl-2 in transgenic mice decreases apoptosis and improves survival in sepsis
-
Hotchkiss RS, Swanson PE, Knudson CM, et al. Overexpression of Bcl-2 in transgenic mice decreases apoptosis and improves survival in sepsis. J Immunol. 1999;162(7):4148-4156
-
(1999)
J Immunol.
, vol.162
, Issue.7
, pp. 4148-4156
-
-
Hotchkiss, R.S.1
Swanson, P.E.2
Knudson, C.M.3
-
47
-
-
64849114020
-
Modulation of the Bcl-2 family blocks sepsis-induced depletion of dendritic cells and macrophages
-
Peck-Palmer OM, Unsinger J, Chang KC, et al. Modulation of the Bcl-2 family blocks sepsis-induced depletion of dendritic cells and macrophages. Shock. 2009;31(4):359-366
-
(2009)
Shock.
, vol.31
, Issue.4
, pp. 359-366
-
-
Peck-Palmer, O.M.1
Unsinger, J.2
Chang, K.C.3
-
48
-
-
84891804430
-
Effect of ghrelin on chronic liver injury and fibrogenesis in male rats: Possible role of nitric oxide
-
Kabil NN, Seddiek HA, Yassin NA, Gamal-Eldin MM. Effect of ghrelin on chronic liver injury and fibrogenesis in male rats: Possible role of nitric oxide. Peptides. 2014;52:90-97
-
(2014)
Peptides.
, vol.52
, pp. 90-97
-
-
Kabil, N.N.1
Seddiek, H.A.2
Yassin, N.A.3
Gamal-Eldin, M.M.4
-
49
-
-
33845910446
-
Ghrelin inhibits apoptosis in hypothalamic neuronal cells during oxygen-glucose deprivation
-
Chung H, Kim E, Lee DH, et al. Ghrelin inhibits apoptosis in hypothalamic neuronal cells during oxygen-glucose deprivation. Endocrinology. 2007;148(1):148-159
-
(2007)
Endocrinology.
, vol.148
, Issue.1
, pp. 148-159
-
-
Chung, H.1
Kim, E.2
Lee, D.H.3
-
50
-
-
84890808606
-
Ghrelin protects human umbilical vein endothelial cells against high glucose-induced apoptosis via mTOR/ P70S6K signaling pathway
-
Zhu J, Zheng C, Chen J, et al. Ghrelin protects human umbilical vein endothelial cells against high glucose-induced apoptosis via mTOR/ P70S6K signaling pathway. Peptides. 2014;52:23-28
-
(2014)
Peptides.
, vol.52
, pp. 23-28
-
-
Zhu, J.1
Zheng, C.2
Chen, J.3
-
51
-
-
0037032817
-
Mitogen-Activated protein kinase path-ways mediated by ERK JNK and p38 protein kinases
-
Johnson GL, Lapadat R. Mitogen-Activated protein kinase path-ways mediated by ERK, JNK, and p38 protein kinases. Science. 2002;298(5600):1911-1912
-
(2002)
Science.
, vol.298
, Issue.5600
, pp. 1911-1912
-
-
Johnson, G.L.1
Lapadat, R.2
-
52
-
-
33847754623
-
The JNK signal transduction pathway
-
Weston CR, Davis RJ. The JNK signal transduction pathway. Curr Opin Cell Biol. 2007;19(2):142-149
-
(2007)
Curr Opin Cell Biol.
, vol.19
, Issue.2
, pp. 142-149
-
-
Weston, C.R.1
Davis, R.J.2
-
53
-
-
67650230896
-
Wnt/ß-catenin signaling: Components, mechanisms, and diseases
-
MacDonald BT, Tamai K, He X. Wnt/ß-catenin signaling: components, mechanisms, and diseases. Dev Cell. 2009;17(1):9-26
-
(2009)
Dev Cell.
, vol.17
, Issue.1
, pp. 9-26
-
-
Macdonald, B.T.1
Tamai, K.2
He, X.3
-
54
-
-
1242267927
-
Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor
-
Sato N, Meijer L, Skaltsounis L, Greengard P, Brivanlou AH. Maintenance of pluripotency in human and mouse embryonic stem cells through activation of Wnt signaling by a pharmacological GSK-3-specific inhibitor. Nat Med. 2004;10(1):55-63
-
(2004)
Nat Med.
, vol.10
, Issue.1
, pp. 55-63
-
-
Sato, N.1
Meijer, L.2
Skaltsounis, L.3
Greengard, P.4
Brivanlou, A.H.5
-
55
-
-
0034720450
-
Axin-induced apoptosis depends on the extent of its JNK activation and its ability to downregulate ß-catenin levels
-
Neo SY, Zhang Y, Yaw LP, Li P, Lin SC. Axin-induced apoptosis depends on the extent of its JNK activation and its ability to downregulate ß-catenin levels. Biochem Biophys Res Commun. 2000; 272(1):144-150
-
(2000)
Biochem Biophys Res Commun.
, vol.272
, Issue.1
, pp. 144-150
-
-
Neo, S.Y.1
Zhang, Y.2
Yaw, L.P.3
Li, P.4
Lin, S.C.5
-
56
-
-
0035104119
-
LPS induction of gene expression in human monocytes
-
Guha M, Mackman N. LPS induction of gene expression in human monocytes. Cell Signal. 2001;13(2):85-94
-
(2001)
Cell Signal.
, vol.13
, Issue.2
, pp. 85-94
-
-
Guha, M.1
Mackman, N.2
-
57
-
-
0842320458
-
A high-throughput quantitative multiplex kinase assay for monitoring information flow in signaling networks: Application to sepsis-Apoptosis
-
Janes KA, Albeck JG, Peng LX, Sorger PK, Lauffenburger DA, Yaffe MB. A high-throughput quantitative multiplex kinase assay for monitoring information flow in signaling networks: Application to sepsis-Apoptosis. Mol Cell Proteomics. 2003;2(7):463-473
-
(2003)
Mol Cell Proteomics.
, vol.2
, Issue.7
, pp. 463-473
-
-
Janes, K.A.1
Albeck, J.G.2
Peng, L.X.3
Sorger, P.K.4
Lauffenburger, D.A.5
Yaffe, M.B.6
-
58
-
-
84867518351
-
Curcumin protects against regional myocardial ischemia/reperfusion injury through activation of RISK/GSK-3ß and inhibition of p38 MAPK and JNK
-
Jeong CW, Yoo KY, Lee SH, Jeong HJ, Lee CS, Kim SJ. Curcumin protects against regional myocardial ischemia/reperfusion injury through activation of RISK/GSK-3ß and inhibition of p38 MAPK and JNK. J Cardiovasc Pharmacol Ther. 2012;17(4):387-394
-
(2012)
J Cardiovasc Pharmacol Ther.
, vol.17
, Issue.4
, pp. 387-394
-
-
Jeong, C.W.1
Yoo, K.Y.2
Lee, S.H.3
Jeong, H.J.4
Lee, C.S.5
Kim, S.J.6
-
59
-
-
53349175016
-
Phosphatidylinositol-3-kinase/ Akt/glycogen synthase kinase-3ß and ERK1/2 pathways mediate protective effects of acylated and unacylated ghrelin against oxygenglucose deprivation-induced apoptosis in primary rat cortical neuronal cells
-
Chung H, Seo S, Moon M, Park S. Phosphatidylinositol-3-kinase/ Akt/glycogen synthase kinase-3ß and ERK1/2 pathways mediate protective effects of acylated and unacylated ghrelin against oxygenglucose deprivation-induced apoptosis in primary rat cortical neuronal cells. J Endocrinol. 2008;198(3):511-521
-
(2008)
J Endocrinol.
, vol.198
, Issue.3
, pp. 511-521
-
-
Chung, H.1
Seo, S.2
Moon, M.3
Park, S.4
-
60
-
-
84871274773
-
Acylated ghrelin protects hippocampal neurons in pilocarpine-induced seizures of immature rats by inhibiting cell apoptosis
-
Zhang R, Yang G, Wang Q, Guo F, Wang H. Acylated ghrelin protects hippocampal neurons in pilocarpine-induced seizures of immature rats by inhibiting cell apoptosis. Mol Biol Rep. 2013; 40(1):51-58
-
(2013)
Mol Biol Rep.
, vol.40
, Issue.1
, pp. 51-58
-
-
Zhang, R.1
Yang, G.2
Wang, Q.3
Guo, F.4
Wang, H.5
-
61
-
-
77950368247
-
Ghrelin inhibits cell apoptosis induced by lipotoxicity in pancreatic ß-cell line
-
Wang W, Zhang D, Zhao H, et al. Ghrelin inhibits cell apoptosis induced by lipotoxicity in pancreatic ß-cell line. Regul Peptides. 2010;161(1-3):43-50
-
(2012)
Regul Peptides.
, vol.161
, Issue.1-3
, pp. 43-50
-
-
Wang, W.1
Zhang, D.2
Zhao, H.3
-
62
-
-
84878799121
-
Multiple signaling pathways mediate ghrelin-induced proliferation of hippocampal neural stem cells
-
Chung H, Li E, Kim Y, Kim S, Park S. Multiple signaling pathways mediate ghrelin-induced proliferation of hippocampal neural stem cells. J Endocrinol. 2013;218(1):49-59
-
(2013)
J Endocrinol.
, vol.218
, Issue.1
, pp. 49-59
-
-
Chung, H.1
Li, E.2
Kim, Y.3
Kim, S.4
Park, S.5
-
63
-
-
79958050031
-
Ghrelin protects spinal cord motoneurons against chronic glutamate-induced excitotoxicity via ERK1/2 and phosphatidylinositol-3-kinase/Akt/glycogen synthase kinase-3ßpathways
-
Lim E, Lee S, Li E, Kim Y, Park S. Ghrelin protects spinal cord motoneurons against chronic glutamate-induced excitotoxicity via ERK1/2 and phosphatidylinositol-3-kinase/Akt/glycogen synthase kinase-3ß pathways. Exp Neurol. 2011;230(1):114-122
-
(2011)
Exp Neurol.
, vol.230
, Issue.1
, pp. 114-122
-
-
Lim, E.1
Lee, S.2
Li, E.3
Kim, Y.4
Park, S.5
-
64
-
-
0037031934
-
Fibroblast growth factor 1 regulates signaling via the glycogen synthase kinase-3ß pathway. Implications for neuroprotection
-
HashimotoM,Sagara Y, Langford D, et al. Fibroblast growth factor 1 regulates signaling via the glycogen synthase kinase-3ß pathway. Implications for neuroprotection. J Biol Chem. 2002;277(36): 32985-32991
-
(2002)
J Biol Chem.
, vol.277
, Issue.36
, pp. 32985-32991
-
-
Hashimotomsagara, Y.1
Langford, D.2
-
65
-
-
4444307751
-
Statins inhibit reoxygenation-induced cardiomyocyte apoptosis: Role for glycogen synthase kinase 3ß and transcription factor ß-catenin
-
Bergmann MW, Rechner C, Freund C, Baurand A, El Jamali A, Dietz R. Statins inhibit reoxygenation-induced cardiomyocyte apoptosis: Role for glycogen synthase kinase 3ß and transcription factor ß-catenin. J Mol Cell Cardiol. 2004;37(3):681-690
-
(2004)
J Mol Cell Cardiol.
, vol.37
, Issue.3
, pp. 681-690
-
-
Bergmann, M.W.1
Rechner, C.2
Freund, C.3
Baurand, A.4
El Jamali, A.5
Dietz, R.6
-
66
-
-
84878633442
-
Simultaneous inactivation of GSK-3ß suppresses quercetin-induced apoptosis by inhibiting the JNK pathway
-
Lee KH, Yoo CG. Simultaneous inactivation of GSK-3ß suppresses quercetin-induced apoptosis by inhibiting the JNK pathway. Am J Physiol Lung Cell Mol Physiol. 2013;304(11):L782-L789
-
(2013)
Am J Physiol Lung Cell Mol Physiol.
, vol.304
, Issue.11
, pp. L782-L789
-
-
Lee, K.H.1
Yoo, C.G.2
-
67
-
-
78649941632
-
Insulin-like growth factor 1 protects human neuroblastoma cells SH-EP1 against MPPß-induced apoptosis by AKT/GSK-3ß/JNK signaling
-
Wang L, Yang HJ, Xia YY, Feng ZW. Insulin-like growth factor 1 protects human neuroblastoma cells SH-EP1 against MPPß-induced apoptosis by AKT/GSK-3ß/JNK signaling. Apoptosis. 2010; 15(12):1470-1479
-
(2012)
Apoptosis.
, vol.15
, Issue.12
, pp. 1470-1479
-
-
Wang, L.1
Yang, H.J.2
Xia, Y.Y.3
Feng, Z.W.4
-
68
-
-
69449101810
-
The links between transcription ß-catenin/JNK signaling and carcinogenesis
-
Saadeddin A, Babaei-Jadidi R, Spencer-Dene B, Nateri AS. The links between transcription, ß-catenin/JNK signaling, and carcinogenesis. Mol Cancer Res. 2009;7(8):1189-1196
-
(2009)
Mol Cancer Res.
, vol.7
, Issue.8
, pp. 1189-1196
-
-
Saadeddin, A.1
Babaei-Jadidi, R.2
Spencer-Dene, B.3
Nateri, A.S.4
-
69
-
-
70350554238
-
JNK phosphorylates ß-catenin and regulates adherens junctions
-
Lee MH, Koria P, Qu J, Andreadis ST. JNK phosphorylates ß-catenin and regulates adherens junctions. FASEB Journal : official publication of the Federation of American Societies for Exp Biol. 2009;23(11):3874-3883.
-
(2009)
FASEB Journal : Official Publication of the Federation of American Societies for Exp Biol.
, vol.23
, Issue.11
, pp. 3874-3883
-
-
Lee, M.H.1
Koria, P.2
Qu, J.3
Andreadis, S.T.4
|