The accuracy of elevated concentrations of endotoxin in bronchoalveolar lavage fluid for the rapid diagnosis of gram-negative pneumonia

American Journal of Respiratory and Critical Care Medicine

Volumn 154, Issue 4 I, 1996, Pages 1020-1028

  Kollef, Marin H ^a   Eisenberg, Paul R ^a   Ohlendorf, Matthew F ^a   Wick, Mark R ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CEFTAZIDIME; CIPROFLOXACIN; ENDOTOXIN; IMIPENEM; PIPERACILLIN; TIMENTIN;

ADULT; ARTICLE; CLINICAL ARTICLE; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; FEMALE; GRAM NEGATIVE INFECTION; GRAM STAINING; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG LAVAGE; MALE; PNEUMONIA; PRIORITY JOURNAL; QUANTITATIVE ASSAY; TOXIN ANALYSIS;

EID: 0029859146     PISSN: 1073449X     EISSN: None     Source Type: Journal    
DOI: 10.1164/ajrccm.154.4.8887601     Document Type: Article

References (35)

1. Torres A., R. Anzar, J. M. Gatell, P. Jimenez, J. Gonzalez, A. Ferrer, R. Celis, and R. Rodriguez-Roisin. 1990. Incidence, risk, and prognosis factors of nosocomial pneumonia in mechanically ventilated patients. Am. Rev. Respir. Dis. 142:523-528.
2. Kollef, M. H. 1993. Ventilator-associated pneumonia: a multivariate analysis. J.A.M.A. 270:1965-1970.
3. Craven, D. E., and K. A. Steger. 1995. Epidemiology of nosocomial pneumonia: new perspectives on an old disease. Chest 108:1S-16S.
4. Rello, J., V. Ausina, M. Ricart, J. Castella, and G. Prats. 1993. Impact of previous antimicrobial therapy on the etiology and outcome of ventilator-associated pneumonia. Chest 104:1230-1235.
5. Kollef, M. H., P. Silver, D. M. Murphy, and E. Trovillion. 1995. The effect of late-onset ventilator-associated pneumonia in determining patient mortality. Chest 108:1655-1662.
6. Fagon, J. Y., J. Chastre, Y. Domart, J. L. Trouillet, J. Pierre, C. Darne, and C. Gibert. 1989. Nosocomial pneumonia in patients receiving continuous mechanical ventilation: prospective analysis of 52 episodes with use of a protected specimen brush and quantitative culture techniques. Am. Rev. Respir. Dis. 139:877-884.
7. Timsit, J. F., B. Misset, B. Renaud, F. W. Goldstein, and J. Carlet. 1995. Effect of previous antimicrobial therapy on the accuracy of the main procedures used to diagnose nosocomial pneumonia in patients who are using ventilation. Chest 108:1036-1040.
8. Luna, C. M., P. Vujacich, C. Vay, J. Matera, C. Gherardi, E. Jolly, F. Santini, and E. Gonzalez Mejia. 1995. Impact of BAL culture result on the therapy and outcome of ventilator-associated pneumonia. Chest 108:145S.
9. Pugin, J., R. Auckenthaler, O. Delaspre, E. van Vessel, and P. M. Suter. 1992. Rapid diagnosis of Gram-negative pneumonia by assay of endotoxin in bronchoalveolar lavage fluid. Thorax 47:547-549.
10. van Deventer, S. J., H. R. Buller, J. W. ten Cate, A. Sturk, and W. Pauw. 1988. Endotoxaemia: an early predictor of septicaemia in febrile patients. Lancet 1:605-609.
11. Dotson, R. G., and S. K. Pingleton. 1993. The effect of antibiotic therapy on recovery of intracellular bacteria from bronchoalveolar lavage in suspected ventilator-associated nosocomial pneumonia. Chest 103: 541-546.
12. Torres, A., M. el-Ebiary, L. Padro, J. Gonzalez, J. P. de la Bellacasa, J. Ramirez, A. Xaubet, M. Ferrer, and R. Rodriquez-Roisin. 1994. Validation of different techniques for the diagnosis of ventilator-associated pneumonia: comparisons with immediate post mortem pulmonary biopsy. Am. J. Respir. Crit. Care Med. 149:324-331.
13. Knaus, W. A., E. A. Draper, D. P. Wagner, and J. E. Zimmerman. 1985. APACHE II: a severity of disease classification system. Crit. Care Med. 13:818-829.
14. Marquette, C. H., H. Georges, F. Wallet, P. Ramon, F. Saulnier, R. Neviere, D. Mathieu, A. Rime, and A. B. Tonnel. 1993. Diagnostic efficiency of endotracheal aspirates with quantitative bacterial cultures in intubated patients with suspected pneumonia: comparison with the protected specimen brush. Am. J. Respir. Crit. Care Med. 148:138-144.
15. Bernard, G. R., A. Artigas, K. L. Brigham, J. Carlet, K. Falke, L. Hudson, M. Lamy, J. R. LeGall, A. Morris, and R. Spragg. 1994. The American-European Consensus Conference on ARDS: definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am. J. Respir. Crit. Care Med. 149:818-824.
16. Pingleton, S. K., J. Y. Fagon, and K. V. Leeper, Jr. 1982. Patient selection for clinical investigation of ventilator-associated pneumonia: criteria for evaluating diagnostic technques. Chest 102:553S-556S.
17. Meduri, G. U., and J. Chastre. 1992. The standardization of bronchoscopic techniques for ventilator-associated pneumonia. Chest 102: 557S-564S.
18. Baselski, V. S., M. el-Torky, J. J. Coalson, and J. P. Griffin. 1992. The standardization of criteria for processing and interpreting laboratory specimens in patients with suspected ventilator-associated pneumonia. Chest 102:571S-579S.
19. Baker, A. M., D. L. Bowton, and E. F. Haponik. 1995. Decision making in nosocomial pneumonia: an analytic approach to the interpretation of quantitative bronchoscopic cultures. Chest 107:85-95.
20. FDA guideline on validation of the Limulus amoebocyte lysate test as an end product endotoxin test for human and animal parenteral drugs, biological products and medical devices. Division of Manufacturing and Product Quality (HFN-32), Office of Compliance, Center for Drug Evaluation and Research. Food and Drug Administration, Rockville, MD. 1987.
21. Fleiss, J. L. 1981. Statistical Methods for Rates and Proportions, 2nd ed. John Wiley, New York. 212-236.
22. Hanley, J. A., and B. J. McNeil. 1982. The meaning and use of the area under the Receiver Operating Characteristic (ROC) curve. Radiology 143:29-36.
23. Moore, R. D., C. R. Smith, and P. S. Lietman. 1984. Association of aminoglycoside plasma levels with therapeutic outcome in gram-negative pneumonia. Am. J. Med. 77:657-662.
24. Rello, J., A. Torres, M. Ricart, J. Valles, J. Gonzalez, A. Artigas, and R. Rodrigues-Roisin. 1994. Ventilator-associated pneumonia by Staphylococcus aureus: comparison of methicillin-resistant and methicillin-sensitive episodes. Am. J. Respir. Crit. Care Med. 50:1545-1549.
25. Kollef, M. H., T. Wragge, and C. Pasque. 1995. Determinants of mortality and multiorgan dysfunction in cardiac surgery patients requiring prolonged mechanical ventilation. Chest 107:1395-1401.
26. Kollef, M. H., and P. Silver. 1995. Ventilator-associated pneumonia: an update for clinicians. Respir. Care 40:1130-1140.
27. Salata, R. A., M. M. Lederman, D. M. Shlaes, M. R. Jacobs, E. Eckstein, D. Tweardy, Z. Toossi, R. Chmielewski, J. Marino, C. H. King, R. C. Graham, and J. J. Ellner. 1987. Diagnosis of nosocomial pneumonia in intubated, intensive care unit patients. Am. Rev. Respir. Dis. 135:426-432.
28. Marquette, C.H., M.C. Copin, F. Wallet, R. Nevierre, F. Saulnier, D. Mathieu, A. Durocher, P. Ramon, and A. B. Tonnel. 1995. Diagnostic tests for pneumonia in ventilated patients: prospective evaluation of diagnostic accuracy using histology as a diagnostic gold standard. Am. J. Respir. Crit. Care Med. 151:1878-1888.
29. Wunderink, R. G., G. B. Russell, E. Mezger, D. Adams, and J. Popovich, Jr. 1991. The diagnostic utility of antibody coated bacteria test in intubated patients. Chest 99:84-88.
30. Shepherd, K. E., K. E. Lynch, J. C. Wain, E. N. Brown, and R. S. Wilson. 1995. Elastin fibers and the diagnosis of bacterial pneumonia in the adult respiratory distress syndrome. Crit. Care Med. 23: 1829-1834.
31. Niederman, M. S., A. Torres, and W. Summer. 1994. Invasive diagnostic testing is not needed routinely to manage suspected ventilator-associated pneumonia. Am. J. Respir. Crit. Care Med. 150:565-569.
32. Chastre, J., J. Y. Fagon, P. Soler, M. Bornet, Y. Domart, J. L. Trouillet, C. Gilbert, and A. J. Hance. 1988. Diagnosis of nosocomial bacterial pneumonia in intubated patients undergoing ventilation: comparison of the usefulness of bronchoalveolar lavage and the protected specimen brush. Am. J. Med. 85:499-506.
33. Hodes, D. S., D. Heon, A. Mass, A. C. Hyatt, and H. L. Hodes. 1987. Reaction of fungal products with amebocyte lysates of the Japanese horseshoe crab, Tachypleus tridentalus. J. Clin. Microbiol. 25: 1701-1704.
34. Papazian, L., T. Pascal, L. Garbe, I. Guignon, X. Thirion, J. Charrel, C. Bollet, P. Fuentes, and F. Gouin. 1995. Bronchoscopic or blind sampling techniques for the diagnosis of ventilator-associated pneumonia. Am. J. Respir. Crit. Care Med. 152:1982-1991.
35. Chastre, J., J.-Y. Fagon, J. L. Trouillet. 1995. Diagnosis and treatment of nosocomial pneumonia in intensive care units. Clin. Infect. Dis. 21:S226-S237.