메뉴 건너뛰기




Volumn 38, Issue 3, 2016, Pages 321-329

TRP functions in the broncho-pulmonary system

Author keywords

Neurogenic inflammation; Oxidative stress; TRPA1; TRPV1

Indexed keywords

TRANSIENT RECEPTOR POTENTIAL CHANNEL; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; VANILLOID RECEPTOR 1; VANILLOID RECEPTOR 4; ISOPROTEIN;

EID: 84963762839     PISSN: 18632297     EISSN: 18632300     Source Type: Journal    
DOI: 10.1007/s00281-016-0557-1     Document Type: Review
Times cited : (43)

References (96)
  • 1
    • 0024642547 scopus 로고
    • Molecular characterization of the Drosophila trp locus: a putative integral membrane protein required for phototransduction
    • COI: 1:CAS:528:DyaK3MXps1Shtg%3D%3D, PID: 2516726
    • Montell C, Rubin GM (1989) Molecular characterization of the Drosophila trp locus: a putative integral membrane protein required for phototransduction. Neuron 2:1313–1323
    • (1989) Neuron , vol.2 , pp. 1313-1323
    • Montell, C.1    Rubin, G.M.2
  • 2
    • 0345059360 scopus 로고    scopus 로고
    • International Union of Pharmacology. XLIII. Compendium of voltage-gated ion channels: transient receptor potential channels
    • PID: 14657417
    • Clapham DE et al (2003) International Union of Pharmacology. XLIII. Compendium of voltage-gated ion channels: transient receptor potential channels. Pharmacol Rev 55:591–596
    • (2003) Pharmacol Rev , vol.55 , pp. 591-596
    • Clapham, D.E.1
  • 3
    • 38449104252 scopus 로고    scopus 로고
    • Transient receptor potential (TRP) cation channels: rewarding unique proteins
    • PID: 18075054
    • Nilius B (2007) Transient receptor potential (TRP) cation channels: rewarding unique proteins. Bull Mem Acad R Med Belg 162:244–253
    • (2007) Bull Mem Acad R Med Belg , vol.162 , pp. 244-253
    • Nilius, B.1
  • 4
    • 84942510072 scopus 로고    scopus 로고
    • Structure of the TRPA1 ion channel suggests regulatory mechanisms
    • COI: 1:CAS:528:DC%2BC2MXht1WksrjM, PID: 26200340
    • Paulsen CE et al (2015) Structure of the TRPA1 ion channel suggests regulatory mechanisms. Nature 525:552
    • (2015) Nature , vol.525 , pp. 552
    • Paulsen, C.E.1
  • 5
    • 84889607320 scopus 로고    scopus 로고
    • Structure of the TRPV1 ion channel determined by electron cryo-microscopy
    • Liao M et al (2014) Structure of the TRPV1 ion channel determined by electron cryo-microscopy. Nature 504:107–112
    • (2014) Nature , vol.504 , pp. 107-112
    • Liao, M.1
  • 6
    • 42349109026 scopus 로고    scopus 로고
    • A primer on ankyrin repeat function in TRP channels and beyond
    • COI: 1:CAS:528:DC%2BD1cXkvFWhtbk%3D, PID: 18414734
    • Gaudet R (2008) A primer on ankyrin repeat function in TRP channels and beyond. Mol Biosyst 4:372–379
    • (2008) Mol Biosyst , vol.4 , pp. 372-379
    • Gaudet, R.1
  • 7
    • 0028831997 scopus 로고
    • Calcium signaling
    • COI: 1:CAS:528:DyaK2MXjtlGnsrY%3D, PID: 7834745
    • Clapham DE (1995) Calcium signaling. Cell 80:259–268
    • (1995) Cell , vol.80 , pp. 259-268
    • Clapham, D.E.1
  • 8
    • 0347719316 scopus 로고    scopus 로고
    • Cell swelling, heat, and chemical agonists use distinct pathways for the activation of the cation channel TRPV4
    • COI: 1:CAS:528:DC%2BD2cXjvFaksQ%3D%3D, PID: 14691263
    • Vriens J et al (2004) Cell swelling, heat, and chemical agonists use distinct pathways for the activation of the cation channel TRPV4. Proc Natl Acad Sci U S A 101:396–401
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 396-401
    • Vriens, J.1
  • 9
    • 33745035395 scopus 로고    scopus 로고
    • Regulation of TRP channels by phosphorylation
    • COI: 1:CAS:528:DC%2BD28XlsFOms70%3D, PID: 16772730
    • Yao X, Kwan HY, Huang Y (2005) Regulation of TRP channels by phosphorylation. Neurosignals 14:273–280
    • (2005) Neurosignals , vol.14 , pp. 273-280
    • Yao, X.1    Kwan, H.Y.2    Huang, Y.3
  • 10
    • 0345616438 scopus 로고    scopus 로고
    • ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures
    • COI: 1:CAS:528:DC%2BD3sXivVWjsbk%3D, PID: 12654248
    • Story GM et al (2003) ANKTM1, a TRP-like channel expressed in nociceptive neurons, is activated by cold temperatures. Cell 112:819–829
    • (2003) Cell , vol.112 , pp. 819-829
    • Story, G.M.1
  • 11
    • 34248138496 scopus 로고    scopus 로고
    • The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept
    • COI: 1:CAS:528:DC%2BD2sXkslyiu7Y%3D, PID: 17464295
    • Szallasi A et al (2007) The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept. Nat Rev Drug Discov 6:357–372
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 357-372
    • Szallasi, A.1
  • 12
    • 0036703646 scopus 로고    scopus 로고
    • Heat-evoked activation of the ion channel, TRPV4
    • COI: 1:CAS:528:DC%2BD38XlvFKnsLw%3D, PID: 12151520
    • Guler AD et al (2002) Heat-evoked activation of the ion channel, TRPV4. J Neurosci 22:6408–6414
    • (2002) J Neurosci , vol.22 , pp. 6408-6414
    • Guler, A.D.1
  • 13
    • 58149401200 scopus 로고    scopus 로고
    • Radial stretch reveals distinct populations of mechanosensitive mammalian somatosensory neurons
    • COI: 1:CAS:528:DC%2BD1cXhsFCmur3E, PID: 19060212
    • Bhattacharya MR et al (2008) Radial stretch reveals distinct populations of mechanosensitive mammalian somatosensory neurons. Proc Natl Acad Sci U S A 105:20015–20020
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 20015-20020
    • Bhattacharya, M.R.1
  • 15
    • 84900806424 scopus 로고    scopus 로고
    • The TRPA1 channel in migraine mechanism and treatment
    • COI: 1:CAS:528:DC%2BC2cXmvV2it7s%3D, PID: 24206166
    • Benemei S et al (2014) The TRPA1 channel in migraine mechanism and treatment. Br J Pharmacol 171:2552–2567
    • (2014) Br J Pharmacol , vol.171 , pp. 2552-2567
    • Benemei, S.1
  • 16
    • 0028990953 scopus 로고
    • Effect of an NK1 receptor antagonist (CP-99,994) on hypertonic saline-induced bronchoconstriction and cough in male asthmatic subjects
    • COI: 1:STN:280:DyaK2Mzpt1yltw%3D%3D, PID: 7663799
    • Fahy JV et al (1995) Effect of an NK1 receptor antagonist (CP-99,994) on hypertonic saline-induced bronchoconstriction and cough in male asthmatic subjects. Am J Respir Crit Care Med 152:879–884
    • (1995) Am J Respir Crit Care Med , vol.152 , pp. 879-884
    • Fahy, J.V.1
  • 17
    • 0035087148 scopus 로고    scopus 로고
    • The NK-2 receptor antagonist SR 48968C does not improve adenosine
    • COI: 1:CAS:528:DC%2BD3MXivVGrs7w%3D, PID: 11251629
    • Kraan J, Vink-Klooster H, Postma DS (2001) The NK-2 receptor antagonist SR 48968C does not improve adenosine. Clin Exp Allergy 31:274–278
    • (2001) Clin Exp Allergy , vol.31 , pp. 274-278
    • Kraan, J.1    Vink-Klooster, H.2    Postma, D.S.3
  • 18
    • 9044235778 scopus 로고    scopus 로고
    • A neurokinin 1-receptor antagonist improves exercise-induced airway narrowing in asthmatic patients
    • COI: 1:STN:280:DyaK287osFeqtg%3D%3D, PID: 8630576
    • Ichinose M et al (1996) A neurokinin 1-receptor antagonist improves exercise-induced airway narrowing in asthmatic patients. Am J Respir Crit Care Med 153:936–941
    • (1996) Am J Respir Crit Care Med , vol.153 , pp. 936-941
    • Ichinose, M.1
  • 19
    • 84896085784 scopus 로고    scopus 로고
    • Antagonism of substance P and perception of breathlessness in patients with chronic obstructive pulmonary disease
    • COI: 1:CAS:528:DC%2BC2cXltl2ksbs%3D, PID: 24582719
    • Mahler DA et al (2014) Antagonism of substance P and perception of breathlessness in patients with chronic obstructive pulmonary disease. Respir Physiol Neurobiol 196:1–7
    • (2014) Respir Physiol Neurobiol , vol.196 , pp. 1-7
    • Mahler, D.A.1
  • 20
    • 84885827972 scopus 로고    scopus 로고
    • TRP channels and pain
    • COI: 1:CAS:528:DC%2BC3sXhvFSqurfK, PID: 24099085
    • Julius D (2013) TRP channels and pain. Annu Rev Cell Dev Biol 29:355–384
    • (2013) Annu Rev Cell Dev Biol , vol.29 , pp. 355-384
    • Julius, D.1
  • 21
    • 0032169804 scopus 로고    scopus 로고
    • The cloned capsaicin receptor integrates multiple pain-producing stimuli
    • COI: 1:CAS:528:DyaK1cXms1eht74%3D, PID: 9768840
    • Tominaga M et al (1998) The cloned capsaicin receptor integrates multiple pain-producing stimuli. Neuron 21:531–543
    • (1998) Neuron , vol.21 , pp. 531-543
    • Tominaga, M.1
  • 22
    • 0032970173 scopus 로고    scopus 로고
    • Vanilloid (Capsaicin) receptors and mechanisms
    • COI: 1:CAS:528:DC%2BD3cXnslChtr8%3D, PID: 10353985
    • Szallasi A, Blumberg PM (1999) Vanilloid (Capsaicin) receptors and mechanisms. Pharmacol Rev 51:159–212
    • (1999) Pharmacol Rev , vol.51 , pp. 159-212
    • Szallasi, A.1    Blumberg, P.M.2
  • 23
    • 33646045075 scopus 로고    scopus 로고
    • TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents
    • COI: 1:CAS:528:DC%2BD28Xjt1Khs70%3D, PID: 16564016
    • Bautista DM et al (2006) TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents. Cell 124:1269–1282
    • (2006) Cell , vol.124 , pp. 1269-1282
    • Bautista, D.M.1
  • 24
    • 84866090064 scopus 로고    scopus 로고
    • Transient receptor potential channels mediate the tussive response to prostaglandin E2 and bradykinin
    • PID: 22693178
    • Grace M et al (2012) Transient receptor potential channels mediate the tussive response to prostaglandin E2 and bradykinin. Thorax 67:891–900
    • (2012) Thorax , vol.67 , pp. 891-900
    • Grace, M.1
  • 25
    • 33646769105 scopus 로고    scopus 로고
    • Sensitization of TRPV1 by EP1 and IP reveals peripheral nociceptive mechanism of prostaglandins
    • PID: 15813989
    • Moriyama T et al (2005) Sensitization of TRPV1 by EP1 and IP reveals peripheral nociceptive mechanism of prostaglandins. Mol Pain 1:3
    • (2005) Mol Pain , vol.1 , pp. 3
    • Moriyama, T.1
  • 26
    • 2342604388 scopus 로고    scopus 로고
    • Protease-activated receptor 2 sensitizes the capsaicin receptor transient receptor potential vanilloid receptor 1 to induce hyperalgesia
    • COI: 1:CAS:528:DC%2BD2cXktFCjt7g%3D, PID: 15128844
    • Amadesi S et al (2004) Protease-activated receptor 2 sensitizes the capsaicin receptor transient receptor potential vanilloid receptor 1 to induce hyperalgesia. J Neurosci 24:4300–4312
    • (2004) J Neurosci , vol.24 , pp. 4300-4312
    • Amadesi, S.1
  • 27
    • 33746662945 scopus 로고
    • (2006). Protease-activated receptor-2 activation exaggerates TRPV1-mediated cough in guinea pigs
    • Gatti R et al (1985) (2006). Protease-activated receptor-2 activation exaggerates TRPV1-mediated cough in guinea pigs. J Appl Physiol 101:506–511
    • (1985) J Appl Physiol , vol.101 , pp. 506-511
    • Gatti, R.1
  • 28
    • 84901187892 scopus 로고    scopus 로고
    • Capsaicin and sensory neurones: a historical perspective
    • COI: 1:CAS:528:DC%2BC2MXmsVCqsbg%3D, PID: 24941663
    • Szolcsanyi J (2014) Capsaicin and sensory neurones: a historical perspective. Prog Drug Res 68:1–37
    • (2014) Prog Drug Res , vol.68 , pp. 1-37
    • Szolcsanyi, J.1
  • 29
    • 79954617292 scopus 로고    scopus 로고
    • Randomised clinical trial: the efficacy of a transient receptor potential vanilloid 1 antagonist AZD1386 in human oesophageal pain
    • COI: 1:CAS:528:DC%2BC3MXnt1emsb8%3D, PID: 21410733
    • Krarup AL et al (2011) Randomised clinical trial: the efficacy of a transient receptor potential vanilloid 1 antagonist AZD1386 in human oesophageal pain. Aliment Pharmacol Ther 33:1113–1122
    • (2011) Aliment Pharmacol Ther , vol.33 , pp. 1113-1122
    • Krarup, A.L.1
  • 30
    • 79954584227 scopus 로고    scopus 로고
    • Oral and cutaneous thermosensory profile of selective TRPV1 inhibition by ABT-102 in a randomized healthy volunteer trial
    • COI: 1:CAS:528:DC%2BC3MXkvVWntbc%3D, PID: 21377273
    • Rowbotham MC et al (2011) Oral and cutaneous thermosensory profile of selective TRPV1 inhibition by ABT-102 in a randomized healthy volunteer trial. Pain 152:1192–1200
    • (2011) Pain , vol.152 , pp. 1192-1200
    • Rowbotham, M.C.1
  • 31
    • 1842475312 scopus 로고    scopus 로고
    • Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin
    • COI: 1:CAS:528:DC%2BD2cXjtValtL8%3D, PID: 15046718
    • Bandell M et al (2004) Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin. Neuron 41:849–857
    • (2004) Neuron , vol.41 , pp. 849-857
    • Bandell, M.1
  • 32
    • 1642430679 scopus 로고    scopus 로고
    • Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1
    • COI: 1:CAS:528:DC%2BD2cXjtFKitg%3D%3D, PID: 14712238
    • Jordt SE et al (2004) Mustard oils and cannabinoids excite sensory nerve fibres through the TRP channel ANKTM1. Nature 427:260–265
    • (2004) Nature , vol.427 , pp. 260-265
    • Jordt, S.E.1
  • 33
    • 24744446008 scopus 로고    scopus 로고
    • Pungent products from garlic activate the sensory ion channel TRPA1
    • COI: 1:CAS:528:DC%2BD2MXps1yqsLg%3D, PID: 16103371
    • Bautista DM et al (2005) Pungent products from garlic activate the sensory ion channel TRPA1. Proc Natl Acad Sci U S A 102:12248–12252
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 12248-12252
    • Bautista, D.M.1
  • 34
    • 59049096524 scopus 로고    scopus 로고
    • TRPA1 acts as a cold sensor in vitro and in vivo
    • COI: 1:CAS:528:DC%2BD1MXhsFyisbg%3D, PID: 19144922
    • Karashima Y et al (2009) TRPA1 acts as a cold sensor in vitro and in vivo. Proc Natl Acad Sci U S A 106:1273–1278
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 1273-1278
    • Karashima, Y.1
  • 35
    • 84877844157 scopus 로고    scopus 로고
    • Novel therapeutic strategy to prevent chemotherapy-induced persistent sensory neuropathy by TRPA1 blockade
    • COI: 1:CAS:528:DC%2BC3sXnsFejsb0%3D, PID: 23477783
    • Trevisan G et al (2013) Novel therapeutic strategy to prevent chemotherapy-induced persistent sensory neuropathy by TRPA1 blockade. Cancer Res 73:3120–3131
    • (2013) Cancer Res , vol.73 , pp. 3120-3131
    • Trevisan, G.1
  • 36
    • 79958744029 scopus 로고    scopus 로고
    • Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation
    • COI: 1:CAS:528:DC%2BC3MXntlGgtb8%3D, PID: 21481532
    • Nassini R et al (2011) Oxaliplatin elicits mechanical and cold allodynia in rodents via TRPA1 receptor stimulation. Pain 152:1621–1631
    • (2011) Pain , vol.152 , pp. 1621-1631
    • Nassini, R.1
  • 37
    • 35449008419 scopus 로고    scopus 로고
    • An ion channel essential for sensing chemical damage
    • COI: 1:CAS:528:DC%2BD2sXht1ekurvN, PID: 17942735
    • Macpherson LJ et al (2007) An ion channel essential for sensing chemical damage. J Neurosci 27:11412–11415
    • (2007) J Neurosci , vol.27 , pp. 11412-11415
    • Macpherson, L.J.1
  • 38
    • 57749107691 scopus 로고    scopus 로고
    • The nociceptor ion channel TRPA1 is potentiated and inactivated by permeating calcium ions
    • COI: 1:CAS:528:DC%2BD1cXhtlOjtLvL, PID: 18775987
    • Wang YY et al (2008) The nociceptor ion channel TRPA1 is potentiated and inactivated by permeating calcium ions. J Biol Chem 283:32691–32703
    • (2008) J Biol Chem , vol.283 , pp. 32691-32703
    • Wang, Y.Y.1
  • 39
    • 33845900989 scopus 로고    scopus 로고
    • TRP channel activation by reversible covalent modification
    • COI: 1:CAS:528:DC%2BD2sXhsVGksg%3D%3D, PID: 17164327
    • Hinman A et al (2006) TRP channel activation by reversible covalent modification. Proc Natl Acad Sci U S A 103:19564–19568
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 19564-19568
    • Hinman, A.1
  • 40
    • 84904905876 scopus 로고    scopus 로고
    • The TRPV4 channel
    • COI: 1:CAS:528:DC%2BC2MXntFOhsbs%3D, PID: 24756711
    • Garcia-Elias A et al (2014) The TRPV4 channel. Handb Exp Pharmacol 222:293–319
    • (2014) Handb Exp Pharmacol , vol.222 , pp. 293-319
    • Garcia-Elias, A.1
  • 41
    • 84863987250 scopus 로고    scopus 로고
    • Expression of transient receptor potential ankyrin 1 in human dental pulp
    • PID: 22794211
    • Kim YS et al (2012) Expression of transient receptor potential ankyrin 1 in human dental pulp. J Endod 38:1087–1092
    • (2012) J Endod , vol.38 , pp. 1087-1092
    • Kim, Y.S.1
  • 42
    • 84896710602 scopus 로고    scopus 로고
    • Increased expression of bronchial epithelial transient receptor potential vanilloid 1 channels in patients with severe asthma
    • PID: 24210884
    • McGarvey LP et al (2014) Increased expression of bronchial epithelial transient receptor potential vanilloid 1 channels in patients with severe asthma. J Allergy Clin Immunol 133(704–12), e4
    • (2014) J Allergy Clin Immunol , vol.133 , Issue.704-12
    • McGarvey, L.P.1
  • 43
    • 84865052691 scopus 로고    scopus 로고
    • Transient receptor potential ankyrin 1 channel localized to non-neuronal airway cells promotes non-neurogenic inflammation
    • COI: 1:CAS:528:DC%2BC38Xht1ejt7bL, PID: 22905134
    • Nassini R et al (2012) Transient receptor potential ankyrin 1 channel localized to non-neuronal airway cells promotes non-neurogenic inflammation. PLoS One 7, e42454
    • (2012) PLoS One , vol.7
    • Nassini, R.1
  • 44
    • 84945317304 scopus 로고    scopus 로고
    • Lung epithelial TRPA1 transduces the extracellular ROS into transcriptional regulation of lung inflammation induced by cigarette smoke: the role of influxed Ca(2)(+)
    • Lin AH et al (2015) Lung epithelial TRPA1 transduces the extracellular ROS into transcriptional regulation of lung inflammation induced by cigarette smoke: the role of influxed Ca(2)(+). Mediat Inflamm 2015:148367
    • (2015) Mediat Inflamm , vol.2015 , pp. 148367
    • Lin, A.H.1
  • 45
    • 80053044013 scopus 로고    scopus 로고
    • Expression of functional TRPA1 receptor on human lung fibroblast and epithelial cells
    • COI: 1:CAS:528:DC%2BC3MXhtFyqsbvP, PID: 21848366
    • Mukhopadhyay I et al (2011) Expression of functional TRPA1 receptor on human lung fibroblast and epithelial cells. J Recept Signal Transduct Res 31:350–358
    • (2011) J Recept Signal Transduct Res , vol.31 , pp. 350-358
    • Mukhopadhyay, I.1
  • 46
    • 84937558478 scopus 로고    scopus 로고
    • The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives
    • COI: 1:CAS:528:DC%2BC2MXhtVaqt7vO, PID: 25765567
    • Nassini R et al (2015) The TRPA1 channel mediates the analgesic action of dipyrone and pyrazolone derivatives. Br J Pharmacol 172:3397–3411
    • (2015) Br J Pharmacol , vol.172 , pp. 3397-3411
    • Nassini, R.1
  • 47
    • 3242663557 scopus 로고    scopus 로고
    • Functional TRPV4 channels are expressed in human airway smooth muscle cells
    • COI: 1:CAS:528:DC%2BD2cXmvVKnu7c%3D, PID: 15075247
    • Jia Y et al (2004) Functional TRPV4 channels are expressed in human airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 287:L272–L278
    • (2004) Am J Physiol Lung Cell Mol Physiol , vol.287 , pp. L272-L278
    • Jia, Y.1
  • 48
    • 84891659190 scopus 로고    scopus 로고
    • TRPV4-mediated calcium influx and ciliary activity in human native airway epithelial cells
    • COI: 1:CAS:528:DC%2BC2cXisFOnsg%3D%3D, PID: 24034343
    • Alenmyr L (2014) TRPV4-mediated calcium influx and ciliary activity in human native airway epithelial cells. Basic Clin Pharmacol Toxicol 114:210–216
    • (2014) Basic Clin Pharmacol Toxicol , vol.114 , pp. 210-216
    • Alenmyr, L.1
  • 49
    • 84915748921 scopus 로고    scopus 로고
    • TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice
    • PID: 25365224
    • Rahaman SO et al (2014) TRPV4 mediates myofibroblast differentiation and pulmonary fibrosis in mice. J Clin Invest 124:5225–5238
    • (2014) J Clin Invest , vol.124 , pp. 5225-5238
    • Rahaman, S.O.1
  • 50
    • 52549101713 scopus 로고    scopus 로고
    • Functional coupling of TRPV4 cationic channel and large conductance, calcium-dependent potassium channel in human bronchial epithelial cell lines
    • COI: 1:CAS:528:DC%2BD1cXhtFCiurjI, PID: 18458941
    • Fernandez-Fernandez JM et al (2008) Functional coupling of TRPV4 cationic channel and large conductance, calcium-dependent potassium channel in human bronchial epithelial cell lines. Pflugers Arch 457:149–159
    • (2008) Pflugers Arch , vol.457 , pp. 149-159
    • Fernandez-Fernandez, J.M.1
  • 51
    • 0033548702 scopus 로고    scopus 로고
    • An ankyrin-like protein with transmembrane domains is specifically lost after oncogenic transformation of human fibroblasts
    • COI: 1:CAS:528:DyaK1MXhvFWqsbk%3D, PID: 10066796
    • Jaquemar D, Schenker T, Trueb B (1999) An ankyrin-like protein with transmembrane domains is specifically lost after oncogenic transformation of human fibroblasts. J Biol Chem 274:7325–7333
    • (1999) J Biol Chem , vol.274 , pp. 7325-7333
    • Jaquemar, D.1    Schenker, T.2    Trueb, B.3
  • 52
    • 84872676834 scopus 로고    scopus 로고
    • Stimulation of the chemosensory TRPA1 cation channel by volatile toxic substances promotes cell survival of small cell lung cancer cells
    • COI: 1:CAS:528:DC%2BC3sXnvVah, PID: 23219522
    • Schaefer EA et al (2013) Stimulation of the chemosensory TRPA1 cation channel by volatile toxic substances promotes cell survival of small cell lung cancer cells. Biochem Pharmacol 85:426–438
    • (2013) Biochem Pharmacol , vol.85 , pp. 426-438
    • Schaefer, E.A.1
  • 53
    • 2542452122 scopus 로고    scopus 로고
    • TRPV channels and modulation by hepatocyte growth factor/scatter factor in human hepatoblastoma (HepG2) cells
    • COI: 1:CAS:528:DC%2BD2cXjs1Cjt7Y%3D, PID: 15126053
    • Vriens J et al (2004) TRPV channels and modulation by hepatocyte growth factor/scatter factor in human hepatoblastoma (HepG2) cells. Cell Calcium 36:19–28
    • (2004) Cell Calcium , vol.36 , pp. 19-28
    • Vriens, J.1
  • 54
    • 44649128517 scopus 로고    scopus 로고
    • TRP channel and cardiovascular disease
    • COI: 1:CAS:528:DC%2BD1cXmvVyks7g%3D, PID: 18508125
    • Watanabe H et al (2008) TRP channel and cardiovascular disease. Pharmacol Ther 118:337–351
    • (2008) Pharmacol Ther , vol.118 , pp. 337-351
    • Watanabe, H.1
  • 55
    • 0025320799 scopus 로고
    • Effects of changes in osmolarity on isolated human airways
    • COI: 1:STN:280:DyaK3c3ntVWktA%3D%3D, PID: 2112128
    • Jongejan RC et al (1990) Effects of changes in osmolarity on isolated human airways. J Appl Physiol 68:1568–1575
    • (1990) J Appl Physiol , vol.68 , pp. 1568-1575
    • Jongejan, R.C.1
  • 56
    • 84896471800 scopus 로고    scopus 로고
    • Transient receptor potential vanilloid 4 activation constricts the human bronchus via the release of cysteinyl leukotrienes
    • PID: 24504097
    • McAlexander MA et al (2014) Transient receptor potential vanilloid 4 activation constricts the human bronchus via the release of cysteinyl leukotrienes. J Pharmacol Exp Ther 349:118–125
    • (2014) J Pharmacol Exp Ther , vol.349 , pp. 118-125
    • McAlexander, M.A.1
  • 57
    • 84869141720 scopus 로고    scopus 로고
    • An orally active TRPV4 channel blocker prevents and resolves pulmonary edema induced by heart failure
    • Thorneloe KS et al (2012) An orally active TRPV4 channel blocker prevents and resolves pulmonary edema induced by heart failure. Sci Transl Med 4, 159ra48
    • (2012) Sci Transl Med , vol.4
    • Thorneloe, K.S.1
  • 58
    • 42549098958 scopus 로고    scopus 로고
    • Negative-feedback loop attenuates hydrostatic lung edema via a cGMP-dependent regulation of transient receptor potential vanilloid 4
    • COI: 1:CAS:528:DC%2BD1cXkvVenu7c%3D, PID: 18323527
    • Yin J et al (2008) Negative-feedback loop attenuates hydrostatic lung edema via a cGMP-dependent regulation of transient receptor potential vanilloid 4. Circ Res 102:966–974
    • (2008) Circ Res , vol.102 , pp. 966-974
    • Yin, J.1
  • 59
    • 84964574527 scopus 로고    scopus 로고
    • What does evidence indicate about the role of TRP channels in inflammatory and immune cells?
    • Parenti A et al (2015) What does evidence indicate about the role of TRP channels in inflammatory and immune cells? Br J Pharmacol 2015:13392
    • (2015) Br J Pharmacol , vol.2015 , pp. 13392
    • Parenti, A.1
  • 60
    • 84908221651 scopus 로고    scopus 로고
    • The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4(+) T cells
    • COI: 1:CAS:528:DC%2BC2cXhs1OrtrbL, PID: 25282159
    • Bertin S et al (2014) The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4(+) T cells. Nat Immunol 15:1055–1063
    • (2014) Nat Immunol , vol.15 , pp. 1055-1063
    • Bertin, S.1
  • 61
    • 84876268807 scopus 로고    scopus 로고
    • The cannabinoid TRPA1 agonist cannabichromene inhibits nitric oxide production in macrophages and ameliorates murine colitis
    • COI: 1:CAS:528:DC%2BC3sXmtFaksrk%3D, PID: 23373571
    • Romano B et al (2013) The cannabinoid TRPA1 agonist cannabichromene inhibits nitric oxide production in macrophages and ameliorates murine colitis. Br J Pharmacol 169:213–229
    • (2013) Br J Pharmacol , vol.169 , pp. 213-229
    • Romano, B.1
  • 62
    • 84938983332 scopus 로고    scopus 로고
    • TRPA1 mediates the effects of hypothermia on the monocyte inflammatory response
    • PID: 26054320
    • Billeter AT et al (2015) TRPA1 mediates the effects of hypothermia on the monocyte inflammatory response. Surgery 158:646–654
    • (2015) Surgery , vol.158 , pp. 646-654
    • Billeter, A.T.1
  • 63
    • 84964611726 scopus 로고    scopus 로고
    • Role of transient receptor potential vanilloid 4 in neutrophil activation and acute lung injury
    • Yin J et al (2015) Role of transient receptor potential vanilloid 4 in neutrophil activation and acute lung injury. Am J Respir Cell Mol Biol 2015:29
    • (2015) Am J Respir Cell Mol Biol , vol.2015 , pp. 29
    • Yin, J.1
  • 64
    • 84896703012 scopus 로고    scopus 로고
    • Transient receptor potential channels and occupational exposure
    • COI: 1:CAS:528:DC%2BC2cXjtlyjtr0%3D, PID: 24451914
    • Geppetti P, Patacchini R, Nassini R (2014) Transient receptor potential channels and occupational exposure. Curr Opin Allergy Clin Immunol 14:77–83
    • (2014) Curr Opin Allergy Clin Immunol , vol.14 , pp. 77-83
    • Geppetti, P.1    Patacchini, R.2    Nassini, R.3
  • 65
    • 84900799033 scopus 로고    scopus 로고
    • Transient receptor potential (TRP) channels in the airway: role in airway disease
    • COI: 1:CAS:528:DC%2BC2cXmvV2it78%3D, PID: 24286227
    • Grace MS et al (2014) Transient receptor potential (TRP) channels in the airway: role in airway disease. Br J Pharmacol 171:2593–2607
    • (2014) Br J Pharmacol , vol.171 , pp. 2593-2607
    • Grace, M.S.1
  • 66
    • 84858740927 scopus 로고    scopus 로고
    • Transient receptor potential genes, smoking, occupational exposures and cough in adults
    • PID: 22443337
    • Smit LA et al (2012) Transient receptor potential genes, smoking, occupational exposures and cough in adults. Respir Res 13:26
    • (2012) Respir Res , vol.13 , pp. 26
    • Smit, L.A.1
  • 67
    • 84906944132 scopus 로고    scopus 로고
    • De novo oligoclonal expansions of circulating plasmablasts in active and relapsing IgG4-related disease
    • COI: 1:CAS:528:DC%2BC2cXnsleksLg%3D, PID: 24815737
    • Mattoo H et al (2014) De novo oligoclonal expansions of circulating plasmablasts in active and relapsing IgG4-related disease. J Allergy Clin Immunol 134:679–687
    • (2014) J Allergy Clin Immunol , vol.134 , pp. 679-687
    • Mattoo, H.1
  • 68
    • 84860519073 scopus 로고    scopus 로고
    • TRPV1 induction in airway vagal low-threshold mechanosensory neurons by allergen challenge and neurotrophic factors
    • COI: 1:CAS:528:DC%2BC38XotVygu78%3D, PID: 22345578
    • Lieu TM et al (2012) TRPV1 induction in airway vagal low-threshold mechanosensory neurons by allergen challenge and neurotrophic factors. Am J Physiol Lung Cell Mol Physiol 302:L941–L948
    • (2012) Am J Physiol Lung Cell Mol Physiol , vol.302 , pp. L941-L948
    • Lieu, T.M.1
  • 69
    • 70350543343 scopus 로고    scopus 로고
    • Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents
    • COI: 1:CAS:528:DC%2BD1MXhsFSkurjJ, PID: 19845671
    • Andre E et al (2009) Transient receptor potential ankyrin receptor 1 is a novel target for pro-tussive agents. Br J Pharmacol 158:1621–1628
    • (2009) Br J Pharmacol , vol.158 , pp. 1621-1628
    • Andre, E.1
  • 70
    • 84932150997 scopus 로고    scopus 로고
    • Transient receptor potential A1 activation prolongs isoflurane induction latency and impairs respiratory function in mice
    • COI: 1:CAS:528:DC%2BC2MXkvFyqtbc%3D, PID: 25646842
    • Li F et al (2015) Transient receptor potential A1 activation prolongs isoflurane induction latency and impairs respiratory function in mice. Anesthesiology 122:768–775
    • (2015) Anesthesiology , vol.122 , pp. 768-775
    • Li, F.1
  • 71
    • 47249119606 scopus 로고    scopus 로고
    • General anesthetics activate a nociceptive ion channel to enhance pain and inflammation
    • COI: 1:CAS:528:DC%2BD1cXot1emtb4%3D, PID: 18574153
    • Matta JA et al (2008) General anesthetics activate a nociceptive ion channel to enhance pain and inflammation. Proc Natl Acad Sci U S A 105:8784–8789
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 8784-8789
    • Matta, J.A.1
  • 72
    • 84919894103 scopus 로고    scopus 로고
    • Pungent general anesthetics activate transient receptor potential-A1 to produce hyperalgesiaand neurogenic bronchoconstriction
    • Eilers H et al (2009) Pungent general anesthetics activate transient receptor potential-A1 to produce hyperalgesiaand neurogenic bronchoconstriction. Anesthesiology
    • (2009) Anesthesiology
    • Eilers, H.1
  • 73
    • 70449587066 scopus 로고    scopus 로고
    • TRPV1 and TRPA1 mediate peripheral nitric oxide-induced nociception in mice
    • PID: 19893614
    • Miyamoto T et al (2009) TRPV1 and TRPA1 mediate peripheral nitric oxide-induced nociception in mice. PLoS One 4, e7596
    • (2009) PLoS One , vol.4
    • Miyamoto, T.1
  • 74
    • 0030200599 scopus 로고    scopus 로고
    • Tachykinin and kinin receptor antagonists: therapeutic perspectives in allergic airway disease
    • COI: 1:CAS:528:DyaK28Xks1eisrs%3D, PID: 8756184
    • Bertrand C, Geppetti P (1996) Tachykinin and kinin receptor antagonists: therapeutic perspectives in allergic airway disease. Trends Pharmacol Sci 17:255–259
    • (1996) Trends Pharmacol Sci , vol.17 , pp. 255-259
    • Bertrand, C.1    Geppetti, P.2
  • 75
    • 0035381322 scopus 로고    scopus 로고
    • Tachykinin receptor antagonists: potential in airways diseases
    • COI: 1:CAS:528:DC%2BC3cXpslKqtg%3D%3D, PID: 11712745
    • Joos GF, Pauwels RA (2001) Tachykinin receptor antagonists: potential in airways diseases. Curr Opin Pharmacol 1:235–241
    • (2001) Curr Opin Pharmacol , vol.1 , pp. 235-241
    • Joos, G.F.1    Pauwels, R.A.2
  • 76
    • 84870555575 scopus 로고    scopus 로고
    • Hypersensitivity of lung vagal C fibers induced by acute intermittent hypoxia in rats: role of reactive oxygen species and TRPA1
    • COI: 1:CAS:528:DC%2BC3sXnvVymtg%3D%3D, PID: 23076873
    • Shen MY et al (2012) Hypersensitivity of lung vagal C fibers induced by acute intermittent hypoxia in rats: role of reactive oxygen species and TRPA1. Am J Physiol Regul Integr Comp Physiol 303:R1175–R1185
    • (2012) Am J Physiol Regul Integr Comp Physiol , vol.303 , pp. R1175-R1185
    • Shen, M.Y.1
  • 77
    • 67049119907 scopus 로고    scopus 로고
    • A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma
    • COI: 1:CAS:528:DC%2BD1MXntlyrsbc%3D, PID: 19458046
    • Caceres AI et al (2009) A sensory neuronal ion channel essential for airway inflammation and hyperreactivity in asthma. Proc Natl Acad Sci U S A 106:9099–9104
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 9099-9104
    • Caceres, A.I.1
  • 78
    • 84884966486 scopus 로고    scopus 로고
    • Hydrogen sulfide induces hypersensitivity of rat capsaicin-sensitive lung vagal neurons: role of TRPA1 receptors
    • COI: 1:CAS:528:DC%2BC3sXhslaisrzL, PID: 23842678
    • Hsu CC et al (2013) Hydrogen sulfide induces hypersensitivity of rat capsaicin-sensitive lung vagal neurons: role of TRPA1 receptors. Am J Physiol Regul Integr Comp Physiol 305:R769–R779
    • (2013) Am J Physiol Regul Integr Comp Physiol , vol.305 , pp. R769-R779
    • Hsu, C.C.1
  • 79
    • 84905638795 scopus 로고    scopus 로고
    • Population of sensory neurons essential for asthmatic hyperreactivity of inflamed airways
    • COI: 1:CAS:528:DC%2BC2cXhtFyqtLjL, PID: 25049382
    • Trankner D et al (2014) Population of sensory neurons essential for asthmatic hyperreactivity of inflamed airways. Proc Natl Acad Sci U S A 111:11515–11520
    • (2014) Proc Natl Acad Sci U S A , vol.111 , pp. 11515-11520
    • Trankner, D.1
  • 80
    • 46749091281 scopus 로고    scopus 로고
    • Cigarette smoke-induced neurogenic inflammation is mediated by alpha, beta-unsaturated aldehydes and the TRPA1 receptor in rodents
    • COI: 1:CAS:528:DC%2BD1cXot1OntbY%3D, PID: 18568077
    • Andre E et al (2008) Cigarette smoke-induced neurogenic inflammation is mediated by alpha, beta-unsaturated aldehydes and the TRPA1 receptor in rodents. J Clin Invest 118:2574–2582
    • (2008) J Clin Invest , vol.118 , pp. 2574-2582
    • Andre, E.1
  • 81
    • 34548101399 scopus 로고    scopus 로고
    • TRPA1 mediates formalin-induced pain
    • COI: 1:CAS:528:DC%2BD2sXps1eqsL8%3D, PID: 17686976
    • McNamara CR et al (2007) TRPA1 mediates formalin-induced pain. Proc Natl Acad Sci U S A 104:13525–13530
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 13525-13530
    • McNamara, C.R.1
  • 82
    • 35748933471 scopus 로고    scopus 로고
    • Transient receptor potential A1 mediates acetaldehyde-evoked pain sensation
    • PID: 17970723
    • Bang S et al (2007) Transient receptor potential A1 mediates acetaldehyde-evoked pain sensation. Eur J Neurosci 26:2516–2523
    • (2007) Eur J Neurosci , vol.26 , pp. 2516-2523
    • Bang, S.1
  • 83
    • 43049090817 scopus 로고    scopus 로고
    • TRPA1 is a major oxidant sensor in murine airway sensory neurons
    • COI: 1:CAS:528:DC%2BD1cXlsF2nur0%3D, PID: 18398506
    • Bessac BF et al (2008) TRPA1 is a major oxidant sensor in murine airway sensory neurons. J Clin Invest 118:1899–1910
    • (2008) J Clin Invest , vol.118 , pp. 1899-1910
    • Bessac, B.F.1
  • 84
    • 41149118183 scopus 로고    scopus 로고
    • Activation of transient receptor potential ankyrin 1 by hydrogen peroxide
    • PID: 18364033
    • Sawada Y et al (2008) Activation of transient receptor potential ankyrin 1 by hydrogen peroxide. Eur J Neurosci 27:1131–1142
    • (2008) Eur J Neurosci , vol.27 , pp. 1131-1142
    • Sawada, Y.1
  • 85
    • 84877974959 scopus 로고    scopus 로고
    • Activation of transient receptor potential ankyrin-1 (TRPA1) in lung cells by wood smoke particulate material
    • COI: 1:CAS:528:DC%2BC3sXkvFKrsL0%3D, PID: 23541125
    • Shapiro D et al (2013) Activation of transient receptor potential ankyrin-1 (TRPA1) in lung cells by wood smoke particulate material. Chem Res Toxicol 26:750–758
    • (2013) Chem Res Toxicol , vol.26 , pp. 750-758
    • Shapiro, D.1
  • 86
    • 55949136832 scopus 로고    scopus 로고
    • Effect of tiotropium on cough reflex sensitivity in acute viral cough
    • PID: 18787899
    • Dicpinigaitis PV et al (2008) Effect of tiotropium on cough reflex sensitivity in acute viral cough. Lung 186:369–374
    • (2008) Lung , vol.186 , pp. 369-374
    • Dicpinigaitis, P.V.1
  • 87
    • 84899109832 scopus 로고    scopus 로고
    • Sensitization by pulmonary reactive oxygen species of rat vagal lung C-fibers: the roles of the TRPV1, TRPA1, and P2X receptors
    • PID: 24699274
    • Ruan T et al (2014) Sensitization by pulmonary reactive oxygen species of rat vagal lung C-fibers: the roles of the TRPV1, TRPA1, and P2X receptors. PLoS One 9, e91763
    • (2014) PLoS One , vol.9
    • Ruan, T.1
  • 88
    • 35348873821 scopus 로고    scopus 로고
    • TRPV4 initiates the acute calcium-dependent permeability increase during ventilator-induced lung injury in isolated mouse lungs
    • COI: 1:CAS:528:DC%2BD2sXht1Wlur3N, PID: 17660328
    • Hamanaka K et al (2007) TRPV4 initiates the acute calcium-dependent permeability increase during ventilator-induced lung injury in isolated mouse lungs. Am J Physiol Lung Cell Mol Physiol 293:L923–L932
    • (2007) Am J Physiol Lung Cell Mol Physiol , vol.293 , pp. L923-L932
    • Hamanaka, K.1
  • 89
    • 84904359102 scopus 로고    scopus 로고
    • TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury
    • COI: 1:CAS:528:DC%2BC2cXht1ygtr%2FI, PID: 24838754
    • Balakrishna S et al (2014) TRPV4 inhibition counteracts edema and inflammation and improves pulmonary function and oxygen saturation in chemically induced acute lung injury. Am J Physiol Lung Cell Mol Physiol 307:L158–L172
    • (2014) Am J Physiol Lung Cell Mol Physiol , vol.307 , pp. L158-L172
    • Balakrishna, S.1
  • 90
    • 79952717349 scopus 로고    scopus 로고
    • An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management
    • PID: 21471066
    • Raghu G et al (2011) An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management. Am J Respir Crit Care Med 183:788–824
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. 788-824
    • Raghu, G.1
  • 91
    • 0036061466 scopus 로고    scopus 로고
    • Transforming growth factor beta stimulates fibroblast-collagen matrix contraction by different mechanisms in mechanically loaded and unloaded matrices
    • COI: 1:CAS:528:DC%2BD38XovFKgsw%3D%3D, PID: 11822880
    • Grinnell F, Ho CH (2002) Transforming growth factor beta stimulates fibroblast-collagen matrix contraction by different mechanisms in mechanically loaded and unloaded matrices. Exp Cell Res 273:248–255
    • (2002) Exp Cell Res , vol.273 , pp. 248-255
    • Grinnell, F.1    Ho, C.H.2
  • 92
    • 85047694529 scopus 로고    scopus 로고
    • Disorders of lung matrix remodeling
    • COI: 1:CAS:528:DC%2BD2cXmsVyktQ%3D%3D, PID: 14722604
    • Chapman HA (2004) Disorders of lung matrix remodeling. J Clin Invest 113:148–157
    • (2004) J Clin Invest , vol.113 , pp. 148-157
    • Chapman, H.A.1
  • 93
    • 84937511107 scopus 로고    scopus 로고
    • TRPV4 is required for hypoxic pulmonary vasoconstriction
    • COI: 1:CAS:528:DC%2BC2MXovF2qsbg%3D, PID: 25815455
    • Goldenberg NM et al (2015) TRPV4 is required for hypoxic pulmonary vasoconstriction. Anesthesiology 122:1338–1348
    • (2015) Anesthesiology , vol.122 , pp. 1338-1348
    • Goldenberg, N.M.1
  • 94
    • 84884254628 scopus 로고    scopus 로고
    • TRPV4 channel contributes to serotonin-induced pulmonary vasoconstriction and the enhanced vascular reactivity in chronic hypoxic pulmonary hypertension
    • COI: 1:CAS:528:DC%2BC3sXhslejtLfJ, PID: 23739180
    • Xia Y et al (2013) TRPV4 channel contributes to serotonin-induced pulmonary vasoconstriction and the enhanced vascular reactivity in chronic hypoxic pulmonary hypertension. Am J Physiol Cell Physiol 305:C704–C715
    • (2013) Am J Physiol Cell Physiol , vol.305 , pp. C704-C715
    • Xia, Y.1
  • 95
    • 84929687611 scopus 로고    scopus 로고
    • Prenatal nicotinic exposure augments cardiorespiratory responses to activation of bronchopulmonary C-fibers
    • PID: 25747962
    • Zhuang J et al (2015) Prenatal nicotinic exposure augments cardiorespiratory responses to activation of bronchopulmonary C-fibers. Am J Physiol Lung Cell Mol Physiol 308:L922–L930
    • (2015) Am J Physiol Lung Cell Mol Physiol , vol.308 , pp. L922-L930
    • Zhuang, J.1
  • 96
    • 84951165094 scopus 로고    scopus 로고
    • Hydrogen peroxide-induced calcium influx in lung microvascular endothelial cells
    • PID: 26453519
    • Suresh K et al (2015) Hydrogen peroxide-induced calcium influx in lung microvascular endothelial cells. Am J Physiol Lung Cell Mol Physiol 309:L1467–L1477
    • (2015) Am J Physiol Lung Cell Mol Physiol , vol.309 , pp. L1467-L1477
    • Suresh, K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.