Hydrogen peroxide-induced calcium influx in lung microvascular endothelial cells involves TRPV4

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 309, Issue 12, 2015, Pages L1467-L1477

  Suresh, Karthik ^a   Servinsky, Laura ^a   Reyes, Jose ^a   Baksh, Syeda ^a   Undem, Clark ^a   Caterina, Michael ^b   Pearse, David B ^a   Shimoda, Larissa A ^a  

^a JOHNS HOPKINS ASTHMA AND ALLERGY CENTER   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Ards; Calcium; Lung injury; Ros; TRPV4

Indexed keywords

2,3 DIHYDRO 2 OXO 3 (4,5,6,7 TETRAHYDRO 1H INDOL 2 YLMETHYLENE) 1H INDOLE 5 SULFONIC ACID DIMETHYLAMIDE; CALCIUM ION; GSK 1016790A; HYDROGEN PEROXIDE; PROTEIN KINASE FYN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 4; VANILLOID RECEPTOR AGONIST; CALCIUM; LEUCINE; N-(1-((4-(2-(((2,4-DICHLOROPHENYL)SULFONYL)AMINO)-3-HYDROXYPROPANOYL)-1-PIPERAZINYL)CARBONYL)-3-METHYLBUTYL)-1-BENZOTHIOPHENE-2-CARBOXAMIDE; PROTEIN TYROSINE KINASE; REACTIVE OXYGEN METABOLITE; SULFONAMIDE; VANILLOID RECEPTOR;

ADULT; ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CAPILLARY ENDOTHELIAL CELL; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; ELECTRIC RESISTANCE; GENE DELETION; HUMAN; HUMAN CELL; LUNG MICROVASCULAR ENDOTHELIAL CELL; MALE; MOUSE; NONHUMAN; PERMEABILITY BARRIER; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; REGULATORY MECHANISM; TRANSMEMBRANE ELECTRICAL RESISTANCE; ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL MEMBRANE; DRUG EFFECTS; ENDOTHELIUM CELL; LUNG; METABOLISM; MICROVASCULATURE; PERMEABILITY; VASCULAR ENDOTHELIUM;

ANIMALS; CALCIUM; CELL MEMBRANE; CELLS, CULTURED; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; HUMANS; HYDROGEN PEROXIDE; LEUCINE; LUNG; MALE; MICE; MICE, INBRED C57BL; MICROVESSELS; PERMEABILITY; PROTO-ONCOGENE PROTEINS C-FYN; REACTIVE OXYGEN SPECIES; SRC-FAMILY KINASES; SULFONAMIDES; TRPV CATION CHANNELS;

EID: 84951165094     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00275.2015     Document Type: Article

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