De novo oligoclonal expansions of circulating plasmablasts in active and relapsing IgG4-related disease

Journal of Allergy and Clinical Immunology

Volumn 134, Issue 3, 2014, Pages 679-687

  Mattoo, Hamid ^a   Mahajan, Vinay S ^a   Della Torre, Emanuel ^a   Sekigami, Yurie ^a   Carruthers, Mollie ^a   Wallace, Zachary S ^a   Deshpande, Vikram ^a   Stone, John H ^a   Pillai, Shiv ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b Cancer Research Center   (United States)

Author keywords

autoreactivity; CDR3; immunoglobulin heavy chain variable region repertoire; next generation sequencing; plasmablasts; rituximab; somatic hypermutation

Indexed keywords

AUTOANTIGEN; IMMUNOGLOBULIN G; LEUKOCYTE ANTIGEN; MONOCLONAL ANTIBODY; RITUXIMAB;

ADULT; AGED; ANTIBODY SPECIFICITY; B LYMPHOCYTE; CELL CLONE; CELL PROLIFERATION; DISEASE COURSE; DRUG EFFECTS; FEMALE; FOLLOW UP; GENETICS; HUMAN; IMMUNE SYSTEM DISEASES; IMMUNOGLOBULIN PRODUCING CELL; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; LYMPHOCYTOSIS; MALE; METABOLISM; MIDDLE AGED; PHYSIOLOGY; RECURRENT DISEASE; SOMATIC HYPERMUTATION; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; ANTIBODIES, MONOCLONAL, MURINE-DERIVED; ANTIBODY DIVERSITY; ANTIBODY-PRODUCING CELLS; ANTIGENS, CD; AUTOANTIGENS; B-LYMPHOCYTES; CELL PROLIFERATION; CLONE CELLS; DISEASE PROGRESSION; FEMALE; FOLLOW-UP STUDIES; HUMANS; IMMUNE SYSTEM DISEASES; IMMUNOGLOBULIN G; LYMPHOCYTE ACTIVATION; LYMPHOCYTOSIS; MALE; MIDDLE AGED; RECURRENCE; SOMATIC HYPERMUTATION, IMMUNOGLOBULIN; YOUNG ADULT;

EID: 84906944132     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2014.03.034     Document Type: Article

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