메뉴 건너뛰기




Volumn 58, Issue 7, 2011, Pages 804-811

Uptake, metabolism and toxicity of hemin in cultured neurons

Author keywords

Brain; HCP1; Heme oxygenase; Hemorrhagic stroke; Rat; ZnPPIX

Indexed keywords

1,10 PHENANTHROLINE; CARRIER PROTEIN; FERRITIN; HEMIN; PROTON COUPLED FOLATE TRANSPORTER; UNCLASSIFIED DRUG;

EID: 79955671381     PISSN: 01970186     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuint.2011.03.006     Document Type: Article
Times cited : (34)

References (38)
  • 2
    • 0026318447 scopus 로고
    • Hemin: A possible physiological mediator of low density lipoprotein oxidation and endothelial injury
    • G. Balla, H.S. Jacob, J.W. Eaton, J.D. Belcher, and G.M. Vercellotti Hemin: a possible physiological mediator of low density lipoprotein oxidation and endothelial injury Arterioscler. Thromb. 11 1991 1700 1711
    • (1991) Arterioscler. Thromb. , vol.11 , pp. 1700-1711
    • Balla, G.1    Jacob, H.S.2    Eaton, J.W.3    Belcher, J.D.4    Vercellotti, G.M.5
  • 3
    • 33744989974 scopus 로고    scopus 로고
    • Inhibition of the ERK/MAP kinase pathway attenuates heme oxygenase-1 expression and heme-mediated neuronal injury
    • DOI 10.1016/j.neulet.2006.01.003, PII S0304394006000140
    • L. Benvenisti-Zarom, J. Chen-Roetling, and R.F. Regan Inhibition of the ERK/MAP kinase pathway attenuates heme oxygenase-1 expression and heme-mediated neuronal injury Neurosci. Lett. 398 2006 230 234 (Pubitemid 44274990)
    • (2006) Neuroscience Letters , vol.398 , Issue.3 , pp. 230-234
    • Benvenisti-Zarom, L.1    Chen-Roetling, J.2    Regan, R.F.3
  • 4
    • 79951960174 scopus 로고    scopus 로고
    • Accumulation of non-transferrin-bound iron by neurons, astrocytes, and microglia
    • G.M. Bishop, T.N. Dang, R. Dringen, and S.R. Robinson Accumulation of non-transferrin-bound iron by neurons, astrocytes, and microglia Neurotox. Res. 19 2011 443 451
    • (2011) Neurotox. Res. , vol.19 , pp. 443-451
    • Bishop, G.M.1    Dang, T.N.2    Dringen, R.3    Robinson, S.R.4
  • 5
    • 33749080071 scopus 로고    scopus 로고
    • Effect of heme oxygenase-1 on the vulnerability of astrocytes and neurons to hemoglobin
    • DOI 10.1016/j.bbrc.2006.09.036, PII S0006291X06020705
    • J. Chen-Roetling, and R.F. Regan Effect of heme oxygenase-1 on the vulnerability of astrocytes and neurons to hemoglobin Biochem. Biophys. Res. Commun. 350 2006 233 237 (Pubitemid 44466598)
    • (2006) Biochemical and Biophysical Research Communications , vol.350 , Issue.1 , pp. 233-237
    • Chen-Roetling, J.1    Regan, R.F.2
  • 6
    • 0032053687 scopus 로고    scopus 로고
    • Kainate-induced apoptosis correlates with c-Jun activation in cultured cerebellar granule cells
    • DOI 10.1002/(SICI)1097-4547(19980401)52:1<69::AID-JNR7>3.0.CO;2-I
    • N.S. Cheung, F.Y. Carroll, J.A. Larm, P.M. Beart, and S.F. Giardina Kainate-induced apoptosis correlates with c-Jun activation in cultured cerebellar granule cells J. Neurosci. Res. 52 1998 69 82 (Pubitemid 28158826)
    • (1998) Journal of Neuroscience Research , vol.52 , Issue.1 , pp. 69-82
    • Cheung, N.S.1    Carroll, F.Y.2    Larm, J.A.3    Beart, P.M.4    Giardina, S.F.5
  • 7
    • 0029947826 scopus 로고    scopus 로고
    • Correlation of membrane lipid peroxidation with oxidation of hemoglobin variants: Possibly related to the rates of hemin release
    • DOI 10.1016/0891-5849(96)00035-4
    • D.T. Chiu, J. van den Berg, F.A. Kuypers, I.J. Hung, J.S. Wei, and T.Z. Liu Correlation of membrane lipid peroxidation with oxidation of hemoglobin variants: possibly related to the rates of hemin release Free Radic. Biol. Med. 21 1996 89 95 (Pubitemid 26230408)
    • (1996) Free Radical Biology and Medicine , vol.21 , Issue.1 , pp. 89-95
    • Chiu, D.T.-Y.1    Van Den Berg, J.2    Kuypers, F.A.3    Hung, I.-J.4    Wei, J.-S.5    Liu, T.-Z.6
  • 8
    • 73349123422 scopus 로고    scopus 로고
    • The putative heme transporter HCP1 is expressed in cultured astrocytes and contributes to the uptake of hemin
    • T.N. Dang, G.M. Bishop, R. Dringen, and S.R. Robinson The putative heme transporter HCP1 is expressed in cultured astrocytes and contributes to the uptake of hemin Glia 58 2010 55 65
    • (2010) Glia , vol.58 , pp. 55-65
    • Dang, T.N.1    Bishop, G.M.2    Dringen, R.3    Robinson, S.R.4
  • 9
    • 0031808935 scopus 로고    scopus 로고
    • Detoxification of exogenous hydrogen peroxide and organic hydroperoxides by cultured astroglial cells assessed by microtiter plate assay
    • DOI 10.1016/S1385-299X(97)00047-0, PII S1385299X97000470
    • R. Dringen, L. Kussmaul, and B. Hamprecht Detoxification of exogenous hydrogen peroxide and organic hydroperoxides by cultured astroglial cells assessed by microtiter plate assay Brain Res. Brain Res. Protoc. 2 1998 223 228 (Pubitemid 28277484)
    • (1998) Brain Research Protocols , vol.2 , Issue.3 , pp. 223-228
    • Dringen, R.1    Kussmaul, L.2    Hamprecht, B.3
  • 10
    • 33750463062 scopus 로고    scopus 로고
    • TNF alpha affects the expression of GFAP and S100B: Implications for Alzheimer's disease
    • DOI 10.1007/s00702-006-0479-5, 100 Years of Alzheimer's Disease
    • M.M. Edwards, and S.R. Robinson TNF alpha affects the expression of GFAP and S100B: implications for Alzheimer's disease J. Neural Transm. 113 2006 1709 1715 (Pubitemid 44657666)
    • (2006) Journal of Neural Transmission , vol.113 , Issue.11 , pp. 1709-1715
    • Edwards, M.M.1    Robinson, S.R.2
  • 12
    • 0034011593 scopus 로고    scopus 로고
    • Hemoglobin potentiates the production of reactive oxygen species by alveolar macrophages
    • L.J. Huffman, P.R. Miles, X. Shi, and L. Bowman Hemoglobin potentiates the production of reactive oxygen species by alveolar macrophages Exp. Lung Res. 26 2000 203 217 (Pubitemid 30241755)
    • (2000) Experimental Lung Research , vol.26 , Issue.3 , pp. 203-217
    • Huffman, L.J.1    Miles, P.R.2    Shi, X.3    Bowman, L.4
  • 13
    • 41549104123 scopus 로고    scopus 로고
    • Functional characterization of PCFT/HCP1 as the molecular entity of the carrier-mediated intestinal folate transport system in the rat model
    • K. Inoue, Y. Nakai, S. Ueda, S. Kamigaso, K.-Y. Ohta, and M. Hatakeyama Functional characterization of PCFT/HCP1 as the molecular entity of the carrier-mediated intestinal folate transport system in the rat model Am. J. Physiol. Gastrointest. Liver Physiol. 294 2008 G660 G668
    • (2008) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.294
    • Inoue, K.1    Nakai, Y.2    Ueda, S.3    Kamigaso, S.4    Ohta, K.-Y.5    Hatakeyama, M.6
  • 16
  • 19
    • 33746890907 scopus 로고    scopus 로고
    • Glutathione peroxidase 1 and glutathione are required to protect mouse astrocytes from iron-mediated hydrogen peroxide toxicity
    • DOI 10.1002/jnr.20957
    • J.R. Liddell, H.H. Hoepken, P.J. Crack, S.R. Robinson, and R. Dringen Glutathione peroxidase 1 and glutathione are required to protect mouse astrocytes from iron-mediated hydrogen peroxide toxicity J. Neurosci. Res. 84 2006 578 586 (Pubitemid 44196698)
    • (2006) Journal of Neuroscience Research , vol.84 , Issue.3 , pp. 578-586
    • Liddell, J.R.1    Hoepken, H.H.2    Crack, P.J.3    Robinson, S.R.4    Dringen, R.5
  • 21
    • 0022632224 scopus 로고
    • Characterization of two constitutive forms of rat liver microsomal heme oxygenase. Only one molecular species of the enzyme is inducible
    • M.D. Maines, G.M. Trakshel, and R.K. Kutty Characterization of two constitutive forms of rat liver microsomal heme oxygenase. Only one molecular species of the enzyme is inducible J. Biol. Chem. 261 1986 411 419 (Pubitemid 16103962)
    • (1986) Journal of Biological Chemistry , vol.261 , Issue.1 , pp. 411-419
    • Maines, M.D.1    Trakshel, G.M.2    Kutty, R.K.3
  • 22
    • 34250367117 scopus 로고    scopus 로고
    • Nonheme-iron histochemistry for light and electron microscopy: A historical, theoretical and technical review
    • DOI 10.1679/aohc.70.1
    • R. Meguro, Y. Asano, S. Odagiri, C. Li, H. Iwatsuki, and K. Shoumura Nonheme-iron histochemistry for light and electron microscopy: a historical, theoretical and technical review Arch. Histol. Cytol. 70 2007 1 19 (Pubitemid 46917489)
    • (2007) Archives of Histology and Cytology , vol.70 , Issue.1 , pp. 1-19
    • Meguro, R.1    Asano, Y.2    Odagiri, S.3    Li, C.4    Iwatsuki, H.5    Shoumura, K.6
  • 23
    • 0027165510 scopus 로고
    • A sensitive post-DAB enhancement technique for demonstration of iron in the central nervous system
    • T. Moos, and K. Mollgard A sensitive post-DAB enhancement technique for demonstration of iron in the central nervous system Histochemistry 99 1993 471 475 (Pubitemid 23208096)
    • (1993) Histochemistry , vol.99 , Issue.6 , pp. 471-475
    • Moos, T.1    Mollgaard, K.2
  • 24
    • 33751244559 scopus 로고    scopus 로고
    • Identification of an Intestinal Folate Transporter and the Molecular Basis for Hereditary Folate Malabsorption
    • DOI 10.1016/j.cell.2006.09.041, PII S009286740601347X
    • A. Qiu, M. Jansen, A. Sakaris, S.H. Min, S. Chattopadhyay, and E. Tsai Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorption Cell 127 2006 917 928 (Pubitemid 44792250)
    • (2006) Cell , vol.127 , Issue.5 , pp. 917-928
    • Qiu, A.1    Jansen, M.2    Sakaris, A.3    Min, S.H.4    Chattopadhyay, S.5    Tsai, E.6    Sandoval, C.7    Zhao, R.8    Akabas, M.H.9    Goldman, I.D.10
  • 26
    • 12944252179 scopus 로고    scopus 로고
    • Heme oxygenase-2 gene deletion attenuates oxidative stress in neurons exposed to extracellular hemin
    • R.F. Regan, J. Chen, and L. Benvenisti-Zarom Heme oxygenase-2 gene deletion attenuates oxidative stress in neurons exposed to extracellular hemin BMC Neurosci. 5 2004 34
    • (2004) BMC Neurosci. , vol.5 , pp. 34
    • Regan, R.F.1    Chen, J.2    Benvenisti-Zarom, L.3
  • 27
    • 0027298460 scopus 로고
    • Neurotoxicity of hemoglobin in cortical cell culture
    • DOI 10.1016/0304-3940(93)90326-G
    • R.F. Regan, and S.S. Panter Neurotoxicity of hemoglobin in cortical cell culture Neurosci. Lett. 153 1993 219 222 (Pubitemid 23147074)
    • (1993) Neuroscience Letters , vol.153 , Issue.2 , pp. 219-222
    • Regan, R.F.1    Panter, S.S.2
  • 28
    • 0034765001 scopus 로고    scopus 로고
    • Activation of extracellular signal-regulated kinases potentiates hemin toxicity in astrocyte cultures
    • DOI 10.1046/j.1471-4159.2001.00590.x
    • R.F. Regan, Y. Wang, X. Ma, A. Chong, and Y. Guo Activation of extracellular signal-regulated kinases potentiates hemin toxicity in astrocyte cultures J. Neurochem. 79 2001 545 555 (Pubitemid 33029928)
    • (2001) Journal of Neurochemistry , vol.79 , Issue.3 , pp. 545-555
    • Regan, R.F.1    Wang, Y.2    Xin, Ma.3    Chong, A.4    Guo, Y.5
  • 29
    • 3242657100 scopus 로고    scopus 로고
    • Colorimetric ferrozine-based assay for the quantitation of iron in cultured cells
    • DOI 10.1016/j.ab.2004.03.049, PII S000326970400301X
    • J. Riemer, H.H. Hoepken, H. Czerwinska, S.R. Robinson, and R. Dringen Colorimetric ferrozine-based assay for the quantitation of iron in cultured cells Anal. Biochem. 331 2004 370 375 (Pubitemid 38953089)
    • (2004) Analytical Biochemistry , vol.331 , Issue.2 , pp. 370-375
    • Riemer, J.1    Hoepken, H.H.2    Czerwinska, H.3    Robinson, S.R.4    Dringen, R.5
  • 30
    • 73949099862 scopus 로고    scopus 로고
    • Hemin toxicity: A preventable source of brain damage following hemorrhagic stroke
    • S.R. Robinson, T.N. Dang, R. Dringen, and G.M. Bishop Hemin toxicity: a preventable source of brain damage following hemorrhagic stroke Redox Rep. 14 2009 228 235
    • (2009) Redox Rep. , vol.14 , pp. 228-235
    • Robinson, S.R.1    Dang, T.N.2    Dringen, R.3    Bishop, G.M.4
  • 31
    • 0141749478 scopus 로고    scopus 로고
    • Heme oxygenase-2 knockout neurons are less vulnerable to hemoglobin toxicity
    • DOI 10.1016/S0891-5849(03)00431-3
    • B. Rogers, V. Yakopson, Z.-P. Teng, Y. Guo, and R.F. Regan Heme oxygenase-2 knockout neurons are less vulnerable to hemoglobin toxicity Free Radic. Biol. Med. 35 2003 872 881 (Pubitemid 37211441)
    • (2003) Free Radical Biology and Medicine , vol.35 , Issue.8 , pp. 872-881
    • Rogers, B.1    Yakopson, V.2    Teng, Z.-P.3    Guo, Y.4    Regan, R.F.5
  • 35
    • 0014348401 scopus 로고
    • The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase
    • USA
    • R. Tenhunen, H.S. Marver, and R. Schmid The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase Proc. Natl. Acad. Sci. U.S.A. 61 1968 748 755
    • (1968) Proc. Natl. Acad. Sci. , vol.61 , pp. 748-755
    • Tenhunen, R.1    Marver, H.S.2    Schmid, R.3
  • 36
    • 0028073463 scopus 로고
    • Brain heme oxygenase isoenzymes and nitric oxide synthase are co-localized in select neurons
    • DOI 10.1016/0306-4522(94)90018-3
    • S.R. Vincent, S. Das, and M.D. Maines Brain heme oxygenase isoenzymes and nitric oxide synthase are co-localized in select neurons Neuroscience 63 1994 223 231 (Pubitemid 24333963)
    • (1994) Neuroscience , vol.63 , Issue.1 , pp. 223-231
    • Vincent, S.R.1    Das, S.2    Maines, M.D.3
  • 37
    • 34250782407 scopus 로고    scopus 로고
    • Heme oxygenase-1 exacerbates early brain injury after intracerebral haemorrhage
    • DOI 10.1093/brain/awm095
    • J. Wang, and S. Dore Heme oxygenase-1 exacerbates early brain injury after intracerebral haemorrhage Brain 130 2007 1643 1652 (Pubitemid 47355932)
    • (2007) Brain , vol.130 , Issue.6 , pp. 1643-1652
    • Wang, J.1    Dore, S.2
  • 38
    • 33744938138 scopus 로고    scopus 로고
    • Heme oxygenase 2 is neuroprotective against intracerebral hemorrhage
    • DOI 10.1016/j.nbd.2005.12.009, PII S0969996105003438
    • J. Wang, H. Zhuang, and S. Dore Heme oxygenase 2 is neuroprotective against intracerebral hemorrhage Neurobiol. Dis. 22 2006 473 476 (Pubitemid 43842118)
    • (2006) Neurobiology of Disease , vol.22 , Issue.3 , pp. 473-476
    • Wang, J.1    Zhuang, H.2    Dore, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.