Nod-like receptor protein 1 inflammasome mediates neuron injury under high glucose

Molecular Neurobiology

Volumn 49, Issue 2, 2014, Pages 673-684

  Meng, Xian Fang ^a   Wang, Xiao Lan ^a   Tian, Xiu Juan ^a   Yang, Zhi Hua ^a   Chu, Guang Pin ^a   Zhang, Jing ^a   Li, Man ^a   Shi, Jing ^a   Zhang, Chun ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

Central nervous system; Diabetes; Inflammatory machinery; Neuron

Indexed keywords

APOPTOSIS ASSOCIATED SPECK LIKE PROTEIN; GLUCOSE; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MEMBRANE PROTEIN; NOD LIKE RECEPTOR PROTEIN 1; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; STREPTOZOCIN; UNCLASSIFIED DRUG; NALP1 PROTEIN, RAT; NERVE PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN CELL; BRAIN CORTEX; CELL VIABILITY; CONTROLLED STUDY; CULTURE MEDIUM; EMBRYO; GENE SILENCING; HYPERGLYCEMIA; HYPOTHESIS; IN VITRO STUDY; MALE; NERVE CELL LESION; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; RAT; STREPTOZOTOCIN-INDUCED DIABETES MELLITUS; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECTS; METABOLISM; NERVE CELL; PHYSIOLOGY; SPRAGUE DAWLEY RAT; TOXICITY;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; CEREBRAL CORTEX; DOSE-RESPONSE RELATIONSHIP, DRUG; GLUCOSE; INFLAMMASOMES; NERVE TISSUE PROTEINS; NEURONS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84896546192     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-013-8551-2     Document Type: Article

References (60)

1. Aachoui Y, Sagulenko V, Miao EA, Stacey KJ (2013) Inflammasome-mediated pyroptotic and apoptotic cell death, and defense against infection. Curr Opin Microbiol 16(3):319-326
2. Abulafia DP, de Rivero Vaccari JP, Lozano JD, Lotocki G, Keane RW, Dietrich WD (2009) Inhibition of the inflammasome complex reduces the inflammatory response after thromboembolic stroke in mice. J Cereb Blood Flow Metab 29(3):534-544
3. Adamczak S, Dale G, de Rivero Vaccari JP, Bullock MR, Dietrich WD, Keane RW (2012) Inflammasome proteins in cerebrospinal fluid of brain-injured patients as biomarkers of functional outcome: clinical article. J Neurosurg 117(6):1119-1125
4. Aronson D (2008) Hyperglycemia and the pathobiology of diabetic complications. Adv Cardiol 45:1-16
5. Benchoua A, Braudeau J, Reis A, Couriaud C, Onteniente B (2004) Activation of proinflammatory caspases by cathepsin B in focal cerebral ischemia. J Cereb Blood Flow Metab 24(11):1272-1279 (Pubitemid 39482490)
6. Bennett MV, Garre JM, Orellana JA, Bukauskas FF, Nedergaard M, Saez JC (2012) Connexin and pannexin hemichannels in inflammatory responses of glia and neurons. Brain Res 1487:3-15
7. Besnard AG, Guillou N, Tschopp J, Erard F, Couillin I, Iwakura Y, Quesniaux V, Ryffel B, Togbe D (2011) NLRP3 inflammasome is required in murine asthma in the absence of aluminum adjuvant. Allergy 66(8):1047-1057
8. Brough D, Pelegrin P, Rothwell NJ (2009) Pannexin-1-dependent caspase-1 activation and secretion of IL-1beta is regulated by zinc. Eur J Immunol 39(2):352-358
9. Carta S, Castellani P, Delfino L, Tassi S, Vene R, Rubartelli A (2009) DAMPs and inflammatory processes: the role of redox in the different outcomes. J Leukoc Biol 86(3):549-555
10. Damiano JS, Reed JC (2004) CARD proteins as therapeutic targets in cancer. Curr Drug Targets 5(4):367-374 (Pubitemid 38559346)
11. de Rivero Vaccari JP, Lotocki G, Alonso OF, Bramlett HM, Dietrich WD, Keane RW (2009) Therapeutic neutralization of the NLRP1 inflammasome reduces the innate immune response and improves histopathology after traumatic brain injury. J Cereb Blood Flow Metab 29(7):1251-1261
12. de Rivero Vaccari JP, Lotocki G, Marcillo AE, Dietrich WD, Keane RW (2008) A molecular platform in neurons regulates inflammation after spinal cord injury. J Neurosci 28(13):3404-3414 (Pubitemid 351469319)
13. Edwards JL, Vincent AM, Cheng HT, Feldman EL (2008) Diabetic neuropathy: mechanisms to management. Pharmacol Ther 120(1):1-34
14. Fazeli SA (2009) Neuroprotection in diabetic encephalopathy. Neurodegener Dis 6(5-6):213-218
15. Felderhoff-Mueser U, Schmidt OI, Oberholzer A, Buhrer C, Stahel PF (2005) IL-18: a key player in neuroinflammation and neurodegeneration? Trends Neurosci 28(9):487-493 (Pubitemid 41187798)
16. Fischer AE, Dolger H (1946) Behavior and psychologic problems of young diabetic patients; a ten to twenty year survey. Arch Intern Med (Chic) 78(6):711-732
17. GattornoM, La ReginaM,Martini A, Manna R (2009) An update on autoinflammatory diseases. New concepts for new and old diseases. Clin Exp Rheumatol 27(2):354-365
18. Ghosh S, Wu MD, Shaftel SS, Kyrkanides S, LaFerla FM, Olschowka JA, O'Banion MK (2013) Sustained interleukin-1beta overexpression exacerbates tau pathology despite reduced amyloid burden in an Alzheimer's mouse model. J Neurosci 33(11):5053-5064
19. Grant RW, Dixit VD (2013) Mechanisms of disease: inflammasome activation and the development of type 2 diabetes. Front Immunol 4:50
20. Gulbransen BD, Bashashati M, Hirota SA, Gui X, Roberts JA, MacDonald JA, Muruve DA, McKay DM, Beck PL, Mawe GM, Thompson RJ, Sharkey KA (2012) Activation of neuronal P2X7 receptor-pannexin-1 mediates death of enteric neurons during colitis. Nat Med 18(4):600-604
21. Hara H, Friedlander RM, Gagliardini V, Ayata C, Fink K, Huang Z, Shimizu-Sasamata M, Yuan J, Moskowitz MA (1997) Inhibition of interleukin 1beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage. ProcNatlAcad Sci U S A 94(5):2007-2012 (Pubitemid 27113952)
22. Hitzler I, Sayi A, Kohler E, Engler DB, Koch KN, HardtWD, Muller A (2012) Caspase-1 has both proinflammatory and regulatory properties in Helicobacter infections,which are differentiallymediated by its substrates IL-1beta and IL-18. J Immunol 188(8):3594-3602
23. Ifuku M, Katafuchi T, Mawatari S, NodaM, Miake K, Sugiyama M, Fujino T (2012) Anti-inflammatory/anti-amyloidogenic effects of plasmalogens in lipopolysaccharide-induced neuroinflammation in adult mice. J Neuroinflammation 9:197
24. Jin Y, Mailloux CM, Gowan K, Riccardi SL, LaBerge G, Bennett DC, Fain PR, Spritz RA (2007) NALP1 in vitiligo-associated multiple autoimmune disease. N Engl J Med 356(12):1216-1225 (Pubitemid 46465597)
25. Kalalian-Moghaddam H, Baluchnejadmojarad T, Roghani M, Goshadrou F, Ronaghi A (2013) Hippocampal synaptic plasticity restoration and anti-apoptotic effect underlie berberine improvement of learning and memory in streptozotocin-diabetic rats. Eur J Pharmacol 698(1-3):259-266
26. Kodl CT, Seaquist ER (2008) Cognitive dysfunction and diabetes mellitus. Endocr Rev 29(4):494-511 (Pubitemid 351831510)
27. Kuhad A, BishnoiM, Tiwari V, Chopra K (2009) Suppression of NF-kappabeta signaling pathway by tocotrienol can prevent diabetes associated cognitive deficits. Pharmacol Biochem Behav 92(2):251-259
28. Kuhad A, Chopra K (2007) Curcumin attenuates diabetic encephalopathy in rats: behavioral and biochemical evidences. Eur J Pharmacol 576(1-3):34-42 (Pubitemid 47588254)
29. Leinninger GM, Backus C, Sastry AM, Yi YB, Wang CW, Feldman EL (2006) Mitochondria in DRG neurons undergo hyperglycemic mediated injury through Bim, Bax and the fission protein Drp1. Neurobiol Dis 23(1):11-22 (Pubitemid 44192383)
30. Li ZG, Zhang W, Grunberger G, Sima AA (2002) Hippocampal neuronal apoptosis in type 1 diabetes. Brain Res 946(2):221-231 (Pubitemid 34876334)
31. Liu ZJ, Liu W, Liu L, Xiao C, Wang Y, Jiao JS (2013) Curcumin protects neuron against cerebral ischemia-induced inflammation through improving PPAR-gamma function. Evid Based Complement Alternat Med 2013:470975
32. Liu F, Lo CF, Ning X, Kajkowski EM, JinM, Chiriac C, Gonzales C, Naureckiene S, Lock YW, Pong K, Zaleska MM, Jacobsen JS, Silverman S, Ozenberger BA (2004) Expression of NALP1 in cerebellar granule neurons stimulates apoptosis. Cell Signal 16(9):1013-1021 (Pubitemid 38798052)
33. Luchsinger JA (2012) Type 2 diabetes and cognitive impairment: linking mechanisms. J Alzheimers Dis 30(Suppl 2):S185-S198
34. Luksch H, Romanowski MJ, Chara O, Tungler V, Caffarena ER, Heymann MC, Lohse P, Aksentijevich I, Remmers EF, Flecks S, Quoos N, Gramatte J, Petzold C, Hofmann SR,Winkler S, Pessler F, Kallinich T, Ganser G, Nimtz-Talaska A, Baumann U, Runde V, Grimbacher B, Birmelin J, Gahr M, Roesler J, Rosen-Wolff A (2013)Naturally occurring genetic variants of human caspase-1 differ considerably in structure and the ability to activate interleukin-1beta. Hum Mutat 34(1):122-131
35. Masters SL, GerlicM,Metcalf D, Preston S, PellegriniM, O'Donnell JA, McArthur K, Baldwin TM, Chevrier S, Nowell CJ, Cengia LH, Henley KJ, Collinge JE, Kastner DL, Feigenbaum L, Hilton DJ, Alexander WS, Kile BT, Croker BA (2012) NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells. Immunity 37(6):1009-1023
36. Mayfield J (1998) Diagnosis and classification of diabetes mellitus: new criteria. Am Fam Physician 58(6):1355-1362, 1369-1370
37. Meek TH,Morton GJ (2012) Leptin, diabetes, and the brain. Indian J Endocrinol Metab 16(Suppl 3):S534-S542
38. Pelegrin P (2008) Targeting interleukin-1 signaling in chronic inflammation: focus on P2X(7) receptor and Pannexin-1. Drug News Perspect 21(8):424-433
39. Pelegrin P, Surprenant A (2006) Pannexin-1 mediates large pore formation and interleukin-1beta release by the ATP-gated P2X7 receptor. EMBO J 25(21):5071-5082 (Pubitemid 44658525)
40. Ravizza T, Lucas SM, Balosso S, Bernardino L, Ku G, Noe F,Malva J, Randle JC, Allan S, Vezzani A (2006) Inactivation of caspase-1 in rodent brain: a novel anticonvulsive strategy. Epilepsia 47(7):1160-1168 (Pubitemid 44086751)
41. Rigato C, Swinnen N, Buckinx R, Couillin I, Mangin JM, Rigo JM, Legendre P, Le Corronc H (2012) Microglia proliferation is controlled by P2X7 receptors in a Pannexin-1-independent manner during early embryonic spinal cord invasion. J Neurosci 32(34):11559-11573
42. Russell JW, Golovoy D, Vincent AM, Mahendru P, Olzmann JA, Mentzer A, Feldman EL (2002) High glucose-induced oxidative stress and mitochondrial dysfunction in neurons. FASEB J 16(13): 1738-1748 (Pubitemid 35340354)
43. Sharma R, Buras E, Terashima T, Serrano F, Massaad CA, Hu L, Bitner B, Inoue T, Chan L, Pautler RG (2010) Hyperglycemia induces oxidative stress and impairs axonal transport rates in mice. PLoS ONE 5(10):e13463
44. Sima AA (2010) Encephalopathies: the emerging diabetic complications. Acta Diabetol 47(4):279-293
45. Sima AA, Zhang W, Kreipke CW, Rafols JA, Hoffman WH (2009) Inflammation in diabetic encephalopathy is prevented by C-peptide. Rev Diabet Stud 6(1):37-42
46. Sollberger G, Strittmatter GE, Garstkiewicz M, Sand J, Beer HD (2013) Caspase-1: the inflammasome and beyond. Innate Immunity
47. Tomura S, de Rivero Vaccari JP, Keane RW, Bramlett HM, Dietrich WD (2012) Effects of therapeutic hypothermia on inflammasome signaling after traumatic brain injury. J Cereb Blood Flow Metab 32(10):1939-1947
48. Tschopp J, Schroder K (2010) NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production? Nat Rev Immunol 10(3):210-215
49. Umegaki H (2012) Neurodegeneration in diabetes mellitus. Adv Exp Med Biol 724:258-265
50. Vargas R, Rincon J, Pedreanez A, Viera N, Hernandez-Fonseca JP, Pena C, Mosquera J (2012) Role of angiotensin II in the brain inflammatory events during experimental diabetes in rats. Brain Res 1453:64-76
51. Vincent AM, Brownlee M, Russell JW (2002) Oxidative stress and programmed cell death in diabetic neuropathy. Ann N Y Acad Sci 959:368-383 (Pubitemid 34457577)
52. Wang X, Song Y, Chen L, Zhuang G, Zhang J, Li M, Meng XF (2013) Contribution of single-minded 2 to hyperglycaemia-induced neurotoxicity. Neurotoxicology 35:106-112
53. Xu XJ, Boumechache M, Robinson LE, Marschall V, Gorecki DC, Masin M, Murrell-Lagnado RD (2012) Splice variants of the P2X7 receptor reveal differential agonist dependence and functional coupling with pannexin-1. J Cell Sci 125(Pt 16):3776-3789
54. Yang RH,Wang F, Hou XH, Cao ZP,Wang B, Xu XN, Hu SJ (2012) Dietary omega-3 polyunsaturated fatty acids improves learning performance of diabetic rats by regulating the neuron excitability. Neuroscience 212:93-103
55. Ye L, Wang F, Yang RH (2011) Diabetes impairs learning performance and affects the mitochondrial function of hippocampal pyramidal neurons. Brain Res 1411:57-64
56. Yin Y, Pastrana JL, Li X, Huang X, Mallilankaraman K, Choi ET, Madesh M, Wang H, Yang XF (2013) Inflammasomes: sensors of metabolic stresses for vascular inflammation. Front Biosci 18:638-649
57. Zhang L, Deng T, Sun Y, Liu K, Yang Y, Zheng X (2008) Role for nitric oxide in permeability of hippocampal neuronal hemichannels during oxygen glucose deprivation. J Neurosci Res 86(10):2281-2291
58. Zhang WH, Wang X, Narayanan M, Zhang Y, Huo C, Reed JC, Friedlander RM (2003) Fundamental role of the Rip2/caspase-1 pathway in hypoxia and ischemia-induced neuronal cell death. Proc Natl Acad Sci U S A 100(26):16012-16017 (Pubitemid 38021106)
59. Zhang X, Xu L, He D, Ling S (2013) Endoplasmic reticulum stress-mediated hippocampal neuron apoptosis involved in diabetic cognitive impairment. Biomed Res Int 2013:924327
60. Zhang WF, Xu YY, Xu KP, Wu WH, Tan GS, Li YJ, Hu CP (2012) Inhibitory effect of selaginellin on high glucose-induced apoptosis in differentiated PC12 cells: role of NADPH oxidase and LOX-1. Eur J Pharmacol 694(1-3):60-68