Hemin inhibits NLRP3 inflammasome activation in sepsis-induced acute lung injury, involving heme oxygenase-1

International Immunopharmacology

Volumn 20, Issue 1, 2014, Pages 24-32

  Luo, Yun Peng ^a   Jiang, Lei ^a   Kang, Kai ^a   Fei, Dong Sheng ^a   Meng, Xiang Lin ^a   Nan, Chuan Chuan ^a   Pan, Shang Ha ^a   Zhao, Ming Ran ^b   Zhao, Ming Yan ^a  

^a THE FIRST AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

^b The Maternal and Child Health Hospital of Harbin City   (China)

Author keywords

Acute lung injury; Heme oxygenase 1; NLRP3 inflammasome; Sepsis

Indexed keywords

CRYOPYRIN; HEME OXYGENASE 1; HEMIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MALONALDEHYDE; PROTOPORPHYRIN ZINC; REACTIVE OXYGEN METABOLITE; APOPTOSIS REGULATORY PROTEIN; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; HMOX1 PROTEIN, MOUSE; MEMBRANE PROTEIN; MESSENGER RNA; PEROXIDASE; PYCARD PROTEIN, MOUSE;

ACUTE LUNG INJURY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISEASE ASSOCIATION; DOWN REGULATION; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; ENZYME REPRESSION; LUNG EDEMA; LUNG HOMOGENATE; LUNG INJURY; LUNG PARENCHYMA; MALE; MOUSE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SEPSIS; UPREGULATION; ANIMAL; BLOOD; C57BL MOUSE; COMPLICATION; DRUG EFFECTS; GENETICS; IMMUNOLOGY; LUNG; METABOLISM; PATHOLOGY;

ACUTE LUNG INJURY; ANIMALS; APOPTOSIS REGULATORY PROTEINS; CARRIER PROTEINS; CASPASE 1; HEME OXYGENASE-1; HEMIN; INFLAMMASOMES; INTERLEUKIN-18; INTERLEUKIN-1BETA; LUNG; MALE; MALONDIALDEHYDE; MEMBRANE PROTEINS; MICE, INBRED C57BL; NF-KAPPA B; PEROXIDASE; REACTIVE OXYGEN SPECIES; RNA, MESSENGER; SEPSIS;

EID: 84895511740     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2014.02.017     Document Type: Article

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