-
1
-
-
32944464648
-
Pathogen recognition and innate immunity
-
Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell. 2006;124:783-801.
-
(2006)
Cell.
, vol.124
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
2
-
-
33746028777
-
Intracellular pattern recognition receptors in the host response
-
Meylan E, Tschopp J, Karin M. Intracellular pattern recognition receptors in the host response. Nature. 2006;442:39-44.
-
(2006)
Nature
, vol.442
, pp. 39-44
-
-
Meylan, E.1
Tschopp, J.2
Karin, M.3
-
3
-
-
68849085894
-
A cell biological view of Toll-like receptor function: Regulation through compartmentalization
-
Barton GM, Kagan JC. A cell biological view of Toll-like receptor function: regulation through compartmentalization. Nat Rev Immunol. 2009;9:535-42.
-
(2009)
Nat. Rev. Immunol.
, vol.9
, pp. 535-542
-
-
Barton, G.M.1
Kagan, J.C.2
-
5
-
-
65649141586
-
Pathogen recognition in the innate immune response
-
Kumar H, Kawai T, Akira S. Pathogen recognition in the innate immune response. Biochem J. 2009;420:1-16.
-
(2009)
Biochem. J.
, vol.420
, pp. 1-16
-
-
Kumar, H.1
Kawai, T.2
Akira, S.3
-
6
-
-
34247566510
-
The family of five: TIR-domaincontaining adaptors in Toll-like receptor signalling
-
O'Neill LA, Bowie AG. The family of five: TIR-domaincontaining adaptors in Toll-like receptor signalling. Nat Rev Immunol. 2007;7:353-64.
-
(2007)
Nat. Rev. Immunol.
, vol.7
, pp. 353-364
-
-
O'Neill, L.A.1
Bowie, A.G.2
-
7
-
-
33847183077
-
Cooperation of Toll-like receptor signals in innate immune defence
-
Trinchieri G, Sher A. Cooperation of Toll-like receptor signals in innate immune defence. Nat Rev Immunol. 2007;7:179-90.
-
(2007)
Nat. Rev. Immunol.
, vol.7
, pp. 179-190
-
-
Trinchieri, G.1
Sher, A.2
-
8
-
-
44649119259
-
Regulation of mitochondrial antiviral signaling pathways
-
Moore CB, Ting JP. Regulation of mitochondrial antiviral signaling pathways. Immunity. 2008;28:735-9.
-
(2008)
Immunity
, vol.28
, pp. 735-739
-
-
Moore, C.B.1
Ting, J.P.2
-
9
-
-
74049126045
-
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production
-
Poeck H, Bscheider M, Gross O, Finger K, Roth S, Rebsamen M, et al. Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production. Nat Immunol. 2010;11:63-9.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 63-69
-
-
Poeck, H.1
Bscheider, M.2
Gross, O.3
Finger, K.4
Roth, S.5
Rebsamen, M.6
-
10
-
-
40449140937
-
The NLR gene family: A standard nomenclature
-
Ting JP, Lovering RC, Alnemri ES, Bertin J, Boss JM, Davis BK, et al. The NLR gene family: a standard nomenclature. Immunity. 2008;28:285-7.
-
(2008)
Immunity
, vol.28
, pp. 285-287
-
-
Ting, J.P.1
Lovering, R.C.2
Alnemri, E.S.3
Bertin, J.4
Boss, J.M.5
Davis, B.K.6
-
12
-
-
69949088960
-
NLR-mediated control of inflammasome assembly in the host response against bacterial pathogens
-
Brodsky IE, Monack D. NLR-mediated control of inflammasome assembly in the host response against bacterial pathogens. Semin Immunol. 2009;21:199-207.
-
(2009)
Semin. Immunol.
, vol.21
, pp. 199-207
-
-
Brodsky, I.E.1
Monack, D.2
-
13
-
-
34548031870
-
The pyroptosome: A supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation
-
Fernandes-Alnemri T, Wu J, Yu JW, Datta P, Miller B, Jankowski W, et al. The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation. Cell Death Differ. 2007;14:1590-604.
-
(2007)
Cell. Death Differ
, vol.14
, pp. 1590-1604
-
-
Fernandes-Alnemri, T.1
Wu, J.2
Yu, J.W.3
Datta, P.4
Miller, B.5
Jankowski, W.6
-
14
-
-
75649106430
-
Intracellular DNA recognition
-
Hornung V, Latz E. Intracellular DNA recognition. Nat Rev Immunol. 2010;10:123-30.
-
(2010)
Nat. Rev. Immunol.
, vol.10
, pp. 123-130
-
-
Hornung, V.1
Latz, E.2
-
15
-
-
63649145255
-
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
-
Fernandes-Alnemri T, Yu JW, Datta P, Wu J, Alnemri ES. AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA. Nature. 2009;458:509-13.
-
(2009)
Nature
, vol.458
, pp. 509-513
-
-
Fernandes-Alnemri, T.1
Yu, J.W.2
Datta, P.3
Wu, J.4
Alnemri, E.S.5
-
16
-
-
63649133278
-
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
-
Hornung V, Ablasser A, Charrel-Dennis M, Bauernfeind F, Horvath G, Caffrey DR, et al. AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC. Nature. 2009;458:514-8.
-
(2009)
Nature
, vol.458
, pp. 514-518
-
-
Hornung, V.1
Ablasser, A.2
Charrel-Dennis, M.3
Bauernfeind, F.4
Horvath, G.5
Caffrey, D.R.6
-
17
-
-
60749104535
-
HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA
-
Roberts TL, Idris A, Dunn JA, Kelly GM, Burnton CM, Hodgson S, et al. HIN-200 proteins regulate caspase activation in response to foreign cytoplasmic DNA. Science. 2009;323:1057-60.
-
(2009)
Science
, vol.323
, pp. 1057-1060
-
-
Roberts, T.L.1
Idris, A.2
Dunn, J.A.3
Kelly, G.M.4
Burnton, C.M.5
Hodgson, S.6
-
18
-
-
60749136484
-
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
-
Burckstummer T, Baumann C, Bluml S, Dixit E, Durnberger G, Jahn H, et al. An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome. Nat Immunol. 2009;10:266-72.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 266-272
-
-
Burckstummer, T.1
Baumann, C.2
Bluml, S.3
Dixit, E.4
Durnberger, G.5
Jahn, H.6
-
19
-
-
68049092912
-
RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway
-
Chiu YH, Macmillan JB, Chen ZJ. RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway. Cell. 2009;138:576-91.
-
(2009)
Cell.
, vol.138
, pp. 576-591
-
-
Chiu, Y.H.1
Macmillan, J.B.2
Chen, Z.J.3
-
20
-
-
70349459734
-
RIG-I-dependent sensing of poly (dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate
-
Ablasser A, Bauernfeind F, Hartmann G, Latz E, Fitzgerald KA, Hornung V. RIG-I-dependent sensing of poly (dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate. Nat Immunol. 2009;10:1065-72.
-
(2009)
Nat. Immunol.
, vol.10
, pp. 1065-1072
-
-
Ablasser, A.1
Bauernfeind, F.2
Hartmann, G.3
Latz, E.4
Fitzgerald, K.A.5
Hornung, V.6
-
21
-
-
44449157593
-
Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules
-
Wang Z, Choi MK, Ban T, Yanai H, Negishi H, Lu Y, et al. Regulation of innate immune responses by DAI (DLM-1/ZBP1) and other DNA-sensing molecules. Proc Natl Acad Sci U S A. 2008;105:5477-82.
-
(2008)
Proc. Natl. Acad. Sci. U S A
, vol.105
, pp. 5477-5482
-
-
Wang, Z.1
Choi, M.K.2
Ban, T.3
Yanai, H.4
Negishi, H.5
Lu, Y.6
-
22
-
-
34547143110
-
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
-
Takaoka A, Wang Z, Choi MK, Yanai H, Negishi H, Ban T, et al. DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response. Nature. 2007;448:501-5.
-
(2007)
Nature
, vol.448
, pp. 501-505
-
-
Takaoka, A.1
Wang, Z.2
Choi, M.K.3
Yanai, H.4
Negishi, H.5
Ban, T.6
-
23
-
-
38949093002
-
TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines
-
Ishii KJ, Kawagoe T, Koyama S, Matsui K, Kumar H, Kawai T, et al. TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines. Nature. 2008;451:725-9.
-
(2008)
Nature
, vol.451
, pp. 725-729
-
-
Ishii, K.J.1
Kawagoe, T.2
Koyama, S.3
Matsui, K.4
Kumar, H.5
Kawai, T.6
-
24
-
-
0037077283
-
The PYRIN-CARD protein ASC is an activating adaptor for caspase-1
-
Srinivasula SM, Poyet JL, Razmara M, Datta P, Zhang Z, Alnemri ES. The PYRIN-CARD protein ASC is an activating adaptor for caspase-1. J Biol Chem. 2002;277:21119-22.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21119-21122
-
-
Srinivasula, S.M.1
Poyet, J.L.2
Razmara, M.3
Datta, P.4
Zhang, Z.5
Alnemri, E.S.6
-
25
-
-
77953583256
-
Interferon-inducible p200-family proteins as novel sensors of cytoplasmic DNA: Role in inflammation and autoimmunity
-
in press. doi:10.1089/jir.2009.0096
-
Choubey D, Duan X, Dickerson E, Ponomareva L, Panchanathan R, Shen H, et al. Interferon-inducible p200-family proteins as novel sensors of cytoplasmic DNA: role in inflammation and autoimmunity. J Interferon Cytokine Res. 2010; in press. doi:10.1089/jir.2009.0096.
-
(2010)
J. Interferon. Cytokine Res.
-
-
Choubey, D.1
Duan, X.2
Dickerson, E.3
Ponomareva, L.4
Panchanathan, R.5
Shen, H.6
-
26
-
-
0037291871
-
A unified model for apical caspase activation
-
Boatright KM, Renatus M, Scott FL, Sperandio S, Shin H, Pedersen IM, et al. A unified model for apical caspase activation. Mol Cell. 2003;11:529-41.
-
(2003)
Mol. Cell.
, vol.11
, pp. 529-541
-
-
Boatright, K.M.1
Renatus, M.2
Scott, F.L.3
Sperandio, S.4
Shin, H.5
Pedersen, I.M.6
-
27
-
-
77951263260
-
The AIM2 inflammasome is critical for innate immunity against F. tularensis
-
in press. doi:10.1038/ni.1859
-
Fernandes-Alnemri T, Yu J, Juliana C, Solorzano L, Kang K, Wu J, et al. The AIM2 inflammasome is critical for innate immunity against F. tularensis. Nature Immunol. 2010; in press. doi:10.1038/ni.1859.
-
(2010)
Nature Immunol.
-
-
Fernandes-Alnemri, T.1
Yu, J.2
Juliana, C.3
Solorzano, L.4
Kang, K.5
Wu, J.6
-
28
-
-
40449097257
-
The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response
-
Muruve DA, Petrilli V, Zaiss AK, White LR, Clark SA, Ross PJ, et al. The inflammasome recognizes cytosolic microbial and host DNA and triggers an innate immune response. Nature. 2008;452:103-7.
-
(2008)
Nature
, vol.452
, pp. 103-107
-
-
Muruve, D.A.1
Petrilli, V.2
Zaiss, A.K.3
White, L.R.4
Clark, S.A.5
Ross, P.J.6
-
29
-
-
1642320635
-
Virus yoga: The role of flexibility in virus host cell recognition
-
Wu E, Nemerow GR. Virus yoga: the role of flexibility in virus host cell recognition. Trends Microbiol. 2004;12:162-9.
-
(2004)
Trends Microbiol.
, vol.12
, pp. 162-169
-
-
Wu, E.1
Nemerow, G.R.2
-
30
-
-
33749264796
-
Autophagy-mediated reentry of Francisella tularensis into the endocytic compartment after cytoplasmic replication
-
Checroun C, Wehrly TD, Fischer ER, Hayes SF, Celli J. Autophagy-mediated reentry of Francisella tularensis into the endocytic compartment after cytoplasmic replication. Proc Natl Acad Sci U S A. 2006;103:14578-83.
-
(2006)
Proc. Natl. Acad. Sci. U S A
, vol.103
, pp. 14578-14583
-
-
Checroun, C.1
Wehrly, T.D.2
Fischer, E.R.3
Hayes, S.F.4
Celli, J.5
-
31
-
-
34848884287
-
Activation of the inflammasome upon Francisella tularensis infection: Interplay of innate immune pathways and virulence factors
-
Henry T, Monack DM. Activation of the inflammasome upon Francisella tularensis infection: interplay of innate immune pathways and virulence factors. Cell Microbiol. 2007;9:2543-51.
-
(2007)
Cell. Microbiol.
, vol.9
, pp. 2543-2551
-
-
Henry, T.1
Monack, D.M.2
-
32
-
-
34249044447
-
Type I interferon signaling is required for activation of the inflammasome during Francisella infection
-
Henry T, Brotcke A, Weiss DS, Thompson LJ, Monack DM. Type I interferon signaling is required for activation of the inflammasome during Francisella infection. J Exp Med. 2007;204:987-94.
-
(2007)
J. Exp. Med.
, vol.204
, pp. 987-994
-
-
Henry, T.1
Brotcke, A.2
Weiss, D.S.3
Thompson, L.J.4
Monack, D.M.5
-
33
-
-
38349019695
-
Phagocytosis-induced apoptosis of macrophages is linked to uptake, killing and degradation of bacteria
-
Frankenberg T, Kirschnek S, Hacker H, Hacker G. Phagocytosis-induced apoptosis of macrophages is linked to uptake, killing and degradation of bacteria. Eur J Immunol. 2008;38:204-15.
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 204-215
-
-
Frankenberg, T.1
Kirschnek, S.2
Hacker, H.3
Hacker, G.4
-
34
-
-
0034098221
-
Bactericidal activity of alveolar macrophages is suppressed by V-ATPase inhibition
-
Bidani A, Reisner BS, Haque AK, Wen J, Helmer RE, Tuazon DM, et al. Bactericidal activity of alveolar macrophages is suppressed by V-ATPase inhibition. Lung. 2000;178:91-104.
-
(2000)
Lung
, vol.178
, pp. 91-104
-
-
Bidani, A.1
Reisner, B.S.2
Haque, A.K.3
Wen, J.4
Helmer, R.E.5
Tuazon, D.M.6
-
35
-
-
65449134827
-
Francisella tularensis phagosomal escape does not require acidification of the phagosome
-
Clemens DL, Lee BY, Horwitz MA. Francisella tularensis phagosomal escape does not require acidification of the phagosome. Infect Immun. 2009;77:1757-73.
-
(2009)
Infect. Immun.
, vol.77
, pp. 1757-1773
-
-
Clemens, D.L.1
Lee, B.Y.2
Horwitz, M.A.3
-
36
-
-
21344468870
-
The Francisella tularensis pathogenicity island protein IglC and its regulator MglA are essential for modulating phagosome biogenesis and subsequent bacterial escape into the cytoplasm
-
Santic M, Molmeret M, Klose KE, Jones S, Kwaik YA. The Francisella tularensis pathogenicity island protein IglC and its regulator MglA are essential for modulating phagosome biogenesis and subsequent bacterial escape into the cytoplasm. Cell Microbiol. 2005;7:969-79.
-
(2005)
Cell. Microbiol.
, vol.7
, pp. 969-979
-
-
Santic, M.1
Molmeret, M.2
Klose, K.E.3
Jones, S.4
Kwaik, Y.A.5
-
37
-
-
26844452231
-
Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis
-
Mariathasan S, Weiss DS, Dixit VM, Monack DM. Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis. J Exp Med. 2005;202:1043-9.
-
(2005)
J. Exp. Med.
, vol.202
, pp. 1043-1049
-
-
Mariathasan, S.1
Weiss, D.S.2
Dixit, V.M.3
Monack, D.M.4
-
38
-
-
0031596298
-
MglA and MglB are required for the intramacrophage growth of Francisella novicida
-
Baron GS, Nano FE. MglA and MglB are required for the intramacrophage growth of Francisella novicida. Mol Microbiol. 1998;29:247-59.
-
(1998)
Mol. Microbiol.
, vol.29
, pp. 247-259
-
-
Baron, G.S.1
Nano, F.E.2
-
39
-
-
77951269392
-
The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
-
in press. doi:10.1038/ni.1864
-
Rathinam VA, Jiang Z, Waggoner SN, Sharma S, Cole LE, Waggoner L, et al. The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses. Nat Immunol. 2010; in press. doi:10.1038/ni.1864.
-
(2010)
Nat. Immunol.
-
-
Rathinam, V.A.1
Jiang, Z.2
Waggoner, S.N.3
Sharma, S.4
Cole, L.E.5
Waggoner, L.6
|