Cytotoxicity of South-African medicinal plants towards sensitive and multidrug-resistant cancer cells

Journal of Ethnopharmacology

Volumn 186, Issue , 2016, Pages 209-223

  Saeed, Mohamed E M ^a   Meyer, Marion ^b   Hussein, Ahmed ^c   Efferth, Thomas ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b UNIVERSITY OF PRETORIA   (South Africa)

^c UNIVERSITY OF THE WESTERN CAPE   (South Africa)

Author keywords

ABC transporters; Chemotherapy; Multidrug resistance; Natural products; Pharmacogenomics; Phytotherapy

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER B5; ACOKANTHERA OPPOSITIFOLIA EXTRACT; ACOVENOSIDE A; ANTINEOPLASTIC AGENT; BREAST CANCER RESISTANCE PROTEIN; CAMPTOTHECIN DERIVATIVE; DOXORUBICIN; HYPOESTES ARISTATA EXTRACT; LAURUS NOBILIS EXTRACT; LEONOTIS LEONURUS EXTRACT; MAMMALIAN TARGET OF RAPAMYCIN INHIBITOR; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE PROTEIN 1; OUABAIN; PLANT EXTRACT; PLECTRANTHUS BARBATUS EXTRACT; PLECTRANTHUS CILIATES EXTRACT; PROTEIN P53; PROTEIN TYROSINE KINASE INHIBITOR; RAS PROTEIN; SALVIA APIANA EXTRACT; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR;

ACANTHACEAE; ACOKANTHERA OPPOSITIFOLIA; APOCYNACEAE; ARTICLE; CONTROLLED STUDY; CROSS RESISTANCE; CYTOTOXICITY; DOSE RESPONSE; DRUG SCREENING; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HYPOESTES ARISTATA; LAMIACEAE; LAURUS NOBILIS; LEONOTIS LEONURUS; LEUKEMIA CELL LINE; LUNG CANCER CELL LINE; MEDICINAL PLANT; MICROARRAY ANALYSIS; MULTIDRUG RESISTANCE; NONHUMAN; ONCOGENE; PHYTOCHEMISTRY; PLECTRANTHUS; PLECTRANTHUS BARBATUS; PLECTRANTHUS CILIATES; RENAL CANCER CELL LINE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SALVIA; SALVIA APIANA; SOUTH AFRICA; TUMOR SUPPRESSOR GENE; AFRICAN MEDICINE; ANGIOSPERM; CELL SURVIVAL; DRUG EFFECTS; DRUG RESISTANCE; NEOPLASMS; TUMOR CELL LINE;

ANGIOSPERMS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; CELL SURVIVAL; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; HUMANS; MEDICINE, AFRICAN TRADITIONAL; NEOPLASMS; PLANT EXTRACTS; PLANTS, MEDICINAL; SOUTH AFRICA;

EID: 84963623037     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2016.04.005     Document Type: Article

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