A pharmacognostical study of 26 South African plant species used as traditional medicines

Pharmaceutical Biology

Volumn 42, Issue 3, 2004, Pages 186-213

  Scott, G ^a   Springfield, E P ^b   Coldrey, N ^b  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b UNIVERSITY OF THE WESTERN CAPE   (South Africa)

Author keywords

Asteraceae; Geraniaceae; Lamiaceae; Quality assurance; South Africa; Traditional medicines; Validation

Indexed keywords

2 PYRONE DERIVATIVE; 7ALPHA HYDROXYROYLEANONE; ACETOPHENONE DERIVATIVE; ALKALOID; ANTHRAQUINONE DERIVATIVE; ARTEMISIN; CARDIAC GLYCOSIDE; CARVONE; DITERPENE; DITERPENOID; ESSENTIAL OIL; FLAVONOID; GUAIANOLIDE DERIVATIVE; LABDANE; LACTONE; LIGNAN; MARRUBIIN; PHYTOSTEROL; PIPERITENONE; PLANT EXTRACT; PREMARRUBIIN; PULEGONE; RHINOCEROTINOIC ACID; SAPONIN; SESQUITERPENE LACTONE; TANNIN; TERPENOID; TETRADENOLIDE; UMURAVUMBOLIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANGIOSPERM; ANIMAL CELL; ANIMAL MODEL; ANTIFUNGAL ACTIVITY; ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTEMISIA AFRA; ARTICLE; ASTERACEAE; BALLOTA AFRICANA; CANDIDA ALBICANS; CONYZA SCABRIDA; CYTOTOXICITY; DRUG ACTIVITY; DRUG EFFICACY; ELYTROPAPPUS RHINOCEROTIS; ERIOCEPALUS AFRICANUS; GERANIACEAE; GERANIUM INCANUM; HELICHRYSUM PATULUM; HELICHRYSUM PETIOLARE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIPPIA FRUTESCENS; HUMAN; HUMAN CELL; LD 50; LEONOTIS LEONURUS; LEONOTIS OCYMIFOLIA; LEYSERA GNAPHALODES; MEDICINAL PLANT; MENTHA LONGIFOLIA; MICROSCOPY; MOUSE; MYCOBACTERIUM SMEGMATIS; NONHUMAN; ONCHOSIPHON SUFFRUTICOSUM; OSMITOPSIS ASTERISCOIDES; PELARGONIUM BETULINUM; PELARGONIUM CUCULLATUM; PELARGONIUM GROSSULARIOIDES; PELARGONIUM PELTATUM; PELARGONIUM TRISTE; PSEUDOMONAS AERUGINOSA; SALVIA AFRICANA CAERULEA; SALVIA AFRICANA LUTEA; SALVIA CHAMELAEAGNEA; SOUTH AFRICA; STACHYS AETHIOPICA; STAPHYLOCOCCUS AUREUS; STOEBE PLUMOSA; TETRADENIA RIPARIA; THIN LAYER CHROMATOGRAPHY; TOXICITY TESTING; TRADITIONAL MEDICINE; TREATMENT INDICATION;

ANIMALIA; ARTEMISIA; ARTEMISIA AFRA; ASTERACEAE; BALLOTA; CANDIDA; CANDIDA ALBICANS; CONYZA; ELYTROPAPPUS RHINOCEROTIS; GERANIACEAE; HELICHRYSUM; HELICHRYSUM PATULUM; HELICHRYSUM PETIOLARE; HIPPIA; LAMIACEAE; LEONOTIS; LEONOTIS LEONURUS; LEONURUS; LEYSERA GNAPHALODES; MAGNOLIOPHYTA; MENTHA LONGIFOLIA; MYCOBACTERIUM; MYCOBACTERIUM SMEGMATIS; OSMITOPSIS; PELARGONIUM; PELARGONIUM BETULINUM; PELARGONIUM CUCULLATUM; PELARGONIUM GROSSULARIOIDES; PELARGONIUM PELTATUM; PELARGONIUM TRISTE; PSEUDOMONAS; PSEUDOMONAS AERUGINOSA; RIPARIA; SALVIA; SALVIA AFRICANA-CAERULEA; STACHYS; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS; STOEBE; TETRADENIA;

EID: 10044220881     PISSN: 13880209     EISSN: None     Source Type: Journal    
DOI: 10.1080/13880200490514032     Document Type: Article

References (76)

1. Anon (1989): The Merck Index, 11th edition. Budivari, ed. Merck & Co., Inc., Rahway, NJ, pp. 1479-1480.
2. Arnold TH, de Wet BC (1993): Plants of Southern Africa: names and distribution. Memoirs of the Botanical Survey of Souther Africa 52. National Botanical Institute, Pretoria.
3. Bauer AW, Kirby WM, Sherds JC, Turck M (1966): Antibiotic susceptibility testing by a standardised single disc method. Am J Clin Pathol 45: 493-496.
4. Bohlmann F, Grenz M, Wegner P, Jakupovic J (1983): Clerodendran derivatives and novel diterpenes from Conyza scabrida DC. Liebig's Ann Chem 11: 2008-2020.
5. Bohlmann F, Zdero C (1972a): Leyserral-angelicat, ein neuartiges benzofuran-derivat. Chemische Berichtunge 105: 2534-2538.
6. Bohlmann F, Zdero C (1972b): Eine neue Guajanolide aus Osmitopsis asteriscoides. Chemische Berichte 105: 1919-1922.
7. Bohlmann F, Zdero C (1974): Neue sequiterpenlacton aus Osmitopsis asteriscoides (L.) Cass. Chemische Berichte 107: 1409-1415.
8. Bohlmann F, Zdero C (1978): New sesquiterpenes and acetylenes from Athanasia and Pentzia species. Phytochemistry 17: 1595-1599.
9. Bohlmann F, Zdero C, Jakupovic J, Rourke JP (1985): cis-Guajanolide aus Osmitopsis asteriscoides. Liebig's Ann Chem 1: 2342-2351.
10. Boily Y, van Puyvelde L (1986): Screening of medicinal plants of Rwanda for antimicrobial activity. J Ethnopharmacol 16: 1-13.
11. Bourweig D, Pohl R (1973): Flavonoids from Mentha longifolia. Planta Med 24: 304-314.
12. British Herbal Medicine Association (1996): British Herbal Pharmacopoeia. Dorset, BHMA.
13. Bruno M (1986): Preleosibirin, a prefuranic labdane diterpene from Ballota nigra ssp. foetida. Phytochemistry 25: 538-539.
14. Cabo J (1985): Accion hipoglucemiante de preparados fitoterapicos contienen especies del genero Salvia. Ars Pharmaceutica 26: 239-249.
15. Campbell WE, Gammon DW, Smith P, Abrahams M, Purves T (1997): Composition and antimalarial activity in vitro of the essential oil of Tetradenia riparia. Planta Med 63: 270-272.
16. Charlson AJ (1980): Antineoplastic constituents of some Southern African plants. J Ethnopharmacol 2: 323-335.
17. Davies-Coleman M, Rivett DEA (1995): Structure of the 5,6-dihydro-α-pyrone umuravumbolide, Phytochemistry 38: 791-792.
18. Deacon HJ (1983): An introduction to the fynbos region: time scales and palaeoenvironments. In: Deacon HJ, Hendey QB, Lambrechts JJN, eds., Fynbos Ecology: a Preliminary Synthesis. South African National Scientific Programmes Report 75, Pretoria, CSIR, pp. 1-20.
19. Evans WC (1996): Trease and Evans' Pharmacognosy, 14th ed. WB Saunders Co. Ltd., London.
20. Dekker TG, Fourie TG, Matthee E, Snyckers FO, van der Schyf CJ (1988): Studies of South African medicinal plants Part 7. Rhinocerotinoic acid: A labdane diterpene with anti-inflammatory properties from Elytropappus rhinocerotis. South African J Chem 41: 33-35.
21. Dekker TG, Fourie TG, Snyckers FO, van der Schyf CJ (1983): Studies of South African medicinal plants. Part 2. Caespitin, a new phloroglucinol derivative with antimicrobial properties from Helichrysum caespitosum. South African J Chem 114: 14-17.
22. Farnsworth NR (1975): Potential value of plants as sources of new antifertility agents. J Pharm Sci 6: 535-598.
23. Goldblatt P (1978): An analysis of the flora of southern Africa: Its characteristics, relationships and origins. Annals of the Missouri Botanic Garden 65: 369-436.
24. Graven E, Deans S, Mavi S, Gundidza MG, Svoboda KP (1992): Antimicrobial and antioxidative properties of the volatile (essential) oil of Artemisia afra Jacq. Flavour Fragrance J 7: 121-123.
25. Graven E, Webber L, Venter M, Gardiner JB (1990): The development of Artemisia afra Jacq. as a new essential oil crop. J Essential Oil Res 2: 215-220.
26. Habtemariam S, Gray AI, Waterman PG (1994): Diterpenes from the leaves of Leonotis ocymifolia var. raineriana. J Nat Prod 57: 1570-1574.
27. Hamburger M, Hostettmann K (1991): Bioactivity in plants: the link between phytochemistry and medicine. Phytochemistry 30: 3864-3874.
28. Harborne JB (1975): Biochemical systematics of flavonoids. In: Harborne JB, Mabry TJ, Mabry H, eds., The Flavonoids. Chapman and Hall, London, pp. 1056-1129.
29. Hegnauer R (1953): The content of essential oil and carvone in various species of mint. Ber Schweiz Bot Ges 63: 90-102.
30. Henderson MS, McCrindle R (1969): Premarrubiin. A diterpenoid from Marrubium vulgare. J Chem Soc C: 2014.
31. Hutchings A (1996): Zulu Medicinal Plants. University of Natal Press, Pietermaritzburg, pp. 326-327.
32. Jakupovic J, Kuhnke J, Schuster A, Metwally MA, Bohlmann F (1986): Phloroglucinol derivatives and other constituents from South African Helichrysum species. Phytochemistry 25: 1133-1142. See also refs. cited therein.
33. Jakupovic J, Klenmeyer H, Bohlmarm F, Graven E (1988): Glaucolides and guaianolides from Artemisia afra. Phytochemistry 27: 1129-1134.
34. Jimenez J (1986): Hypoglycaemic activity of Salvia lavandulifolia. Planta Med 52: 260-262.
35. Laonigro G, Lanzetta R, Parrilli M, Adolfini M, Mangoni L (1979): The configuration of the diterpene spiroethers from Marrubium vulgare and from Leonotis leonurus. Gazetta Chimica Italia 109: 145-150.
36. Latté KP (1999): Phytochemische und Pharmakologische Untersuchungen an Pelargonium reniforme Curt. Ph.D. Thesis, Freien Universität, Berlin.
37. Lis-Balchin MT (1996): A chemotaxonomic reappraisal of the section Pelargonium: Ciconium (Geraniaceae). South African J Botany 62: 277-279.
38. Lis-Balchin MT, Hart S. (1994): A pharmacological appraisal of the folk medicinal use of Pelargonium grossularioides and Erodium cicutarium (Geraniaceae). J Herbs, Spices Nat Prod 2: 41-48.
39. Mathekga ADM, Meyer JJM (1998): Antibacterial activity of South African Helichrysum species. South African J Botany 64: 293-295.
40. Middleton EJR, Kandaswami C (1993): The impact of plant flavonoids on mammalian biology: implications for immunity, inflammation and cancer. In: Harborne JB ed., The Flavonoids: Advances in Research since 1986. Chapman and Hall, London, pp. 619-652.
41. 450 in vivo and in vitro. Journal of the Indian Institute of Science 71(I): 76-78.
42. Newall CA, Anderson L, Phillipson JD (1996): Herbal Medicines - A Guide for Health Care Professionals. The Pharmaceutical Press, London.
43. Pharmaceotical Society of Great Britain (1939): British Pharmacentical Lodex, The Pharmaceotical Press, London.
44. Savona G, Piozzi F, Hanson JR, Siverns M (1976): Structure of ballotinone, a diterpenoid from Ballota nigra. J Chem Soc Perkin Trans 1: 1607-1609.
45. Savona G, Piozzi F, Hanson JR, Siverns M (1977a): The structure of ballotenol, a new diterpenoid from Ballota nigra. J Chem Soc Perkin Trans 1: 497-499.
46. Savona G, Piozzi F, Hanson JR, Siverns M (1977b): Structures of three new diterpenoids from Ballota species. J Chem Soc Perkin Trans 1: 322-324.
47. Silbernagel E, Spreitzer H, Buchbauer G (1990): Non-volatile constituents of Artemisia afra. Monatsch Chem 121: 433-436.
48. Sticher VO, Fluck H (1968): Composition of genuine extracted and distilled essential oils of some Mentha species. Pharmaceutica Acta Hevetica 43: 411-415.
49. Thomassen D (1990): Menthofuran-dependent and independent aspects of pulegone hepatotoxicity: Roles of glutathione. J Pharmacol Exp Ther 253: 567-572.
50. Tisserand R, Balacs T (1995): Essential Oil Safety: A Guide for Health Care Professionals. Churchill Livingstone, Edinburgh, pp. 199-200.
51. Treurnicht FT (1997): An evaluation of the toxic and potential antiviral effects of some plants used by South Africans for medicinal purposes. M.Sc. Thesis, University of Stellenbosch.
52. Tsichritzis F, Jakupovic J (1991): Diterpenes from Leyssera gnaphaloides. Phytochemistry 30: 211-213.
53. Tyler VE (1993): The Honest Herbal, 3rd ed. The Haworth Press Inc., New York.
54. Van der Walt JJA (1977): Pelargoniums of Southern Africa, Vol. 1. Purnell, Cape Town.
55. Van der Walt JJA, Vorster PJ (1981): Pelargoniums of Southern Africa, Vol. 2. Juta and Co. Ltd., Cape Town.
56. Van der Walt JJA, Vorster PJ (1988): Pelargoniums of Southern Africa, Vol. 3. National Botanic Gardens, Kirstenbosch.
57. Van Puyvelde L, Dube S, Umiwana E, Uwera C, Dommisse RA, Esmans EL, van Schoor O, Vlietinck A (1979): New α-pyrones from Iboza riparia. Phytochemistry 18: 1215-1218.
58. Van Puyvelde L, Lefebvre R, Mugabo P, de Kimpe N, Schamp N (1987): Active principles of Tetradenia riparia. II. Anti-spasmodic activity of 8 (14), 15-sandaracopimaradiene-7α,18-diol. Planta Med 52: 156-158.
59. Van Puyvelde L, Ntawukiliyayo JD, Portaels L, Hakizamangu E (1994): In vivo inhibition of mycobacteria by Rwandese medicinal plants. Phytother Res 8: 65-69.
60. Van Puyvelde L, Nyirankuliza S, Panebianco R, Boily Y, Geizer I, Sebikali B, de Kimpe N, Schamp N (1986): Active principles of Tetradenia riparia. I. Antimicrobial activity of 8 (14), 15-sandaracopimaradiene-7α,18-diol. J Ethnopharmacol 77: 269-273.
61. Vlietinck AJ, van Hoof L, Totté J, Lasure A, vanden Berghe D, Rwangabo PC, Mvukiyumwani J (1995): Screening of a hundred Rwandese plants for antimicrobial and antiviral properties. J Ethnopharmacol 46: 31-47.
62. Watt JM, Breyer-Brandwijk MG (1962): Medicinal and Poisonous Plants of Southern and Eastern Africa, 2nd ed. E. and S. Livingstone Ltd., London.
63. Weenen H, Nkunya MHH, Bray D, Mwasumbi LB, Kinabo LS, Kilimali VA (1990): Antimalarial activity of Tanzanian medicinal plants. Planta Med 56: 368-370.
64. Wollenweber E, Mann K, Valant-Vetschera KM (1989): External flavonoid aglycones in Artemisia and some further Anthemidae (Asteraceae). Fitoterapia 60: 460-463.
65. Winter CA, Nuss GW (1966): An assessment of anti-arthritic activity of the labdane diterpene rhinocerotinocic acid. Arthr Rheum 9: 394-397.
66. Winter CA, Risley EA, Nuss GW (1962): Anti-inflammatory activity of the labdane diterpene rhinocerotinoic acid in the rat. Proc Soc Exp Biol Med 111: 544-547.
67. WHO (1978): The Promotion and Development of Traditional Medicine. WHO Technical Report 622. WHO, Geneva.
68. WHO (1993): Research Guidelines for Evaluating the Safety and Efficacy of Herbal Medicines. WHO, Geneva.
69. WHO (1998): Quality Control Methods for Medicinal Plant Materials. WHO, Geneva.
70. WHO (1999): WHO Monographs on Selected Medicinal Plants, Vol. 1. WHO, Geneva.
71. WHO (2001): WHO Monographs on Selected Medicinal Plants, Vol. 2. WHO, Geneva.
72. WHO (2002): WHO Monographs on Selected Medicinal Plants, Vol. 3. WHO, Geneva.
73. WHO/IUCN/WWF (1993): Guidelines on the Conservation of Medicinal Plants. IUCN, Gland, Switzerland.
74. Zdero C, Bohlmann F (1990): Glaucolides, fulvenoguianolides and other sesquiterpene lactones from Pentzia species. Phytochemistry 29: 189-194.
75. Zdero C, Bohlmann F, Muller M (1987): Sesquiterpene lactones and other constituents from Eriocephalus species, Phytochemistry 26: 2763-2775.
76. Zelnik R, Rabenhorst E, Matida A, Gottlieb HE, Lavie D, Panizza S (1978): Ibozol, a new diterpenoid from Iboza riparia. Phytochemistry 17: 1795-1797.