Hot water soluble sesquiterpenes [anhydroperoxy-costunolide and 3-oxoeudesma-1,4(15),11(13)triene-12,6α-olide]isolated from laurel (Laurus nobilis L.) induce cell death and morphological change indicative of apoptotic chromatin condensation in leukemia cells

Oncology Reports

Volumn 11, Issue 1, 2004, Pages 85-88

  Komiya, Takashi ^a   Yamada, Yayoi ^a   Moteki, Hiroyuki ^a   Katsuzaki, Hirotaka ^a   Imai, Kunio ^a   Hibasami, Hiroshige ^b  

^a MIE UNIVERSITY   (Japan)

^b MIE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Apoptotic chromatin condensation; Growth inhibition; Hot water soluble (HWS) sesquiterpenes; Human promyelotic leukemia

Indexed keywords

3 OXO EUDESMA 1,4(15),11(13)TRIENE 12,6ALPHA OLIDE; 3-OXO-EUDESMA-1,4(15),11(13)TRIENE-12,6ALPHA-OLIDE; ANHYDROPEROXYCOSTUNOLIDE; DNA FRAGMENT; PLANT EXTRACT; SESQUITERPENE;

APOPTOSIS; ARTICLE; CELL DIVISION; CELL SIZE; CELL STRAIN HL 60; CHEMISTRY; CHROMATIN; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECT; FLOW CYTOMETRY; HUMAN; ISOLATION AND PURIFICATION; LAURUS; LEUKEMIA; METABOLISM; PATHOLOGY; SOLUBILITY;

APOPTOSIS; CELL DIVISION; CELL SIZE; CHROMATIN; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; HL-60 CELLS; HUMANS; LAURUS; LEUKEMIA; PLANT EXTRACTS; SESQUITERPENES; SESQUITERPENES, EUDESMANE; SOLUBILITY;

EID: 3543126648     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.11.1.85     Document Type: Article

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