Sodium/potasium ATPase (Na+, K+-ATPase) and ouabain/related cardiac glycosides: A new paradigm for development of anti- breast cancer drugs?

Breast Cancer Research and Treatment

Volumn 96, Issue 1, 2006, Pages 1-15

  Chen, Jin Qiang ^a   Contreras, Ruben G ^b   Wang, Richard ^a   Fernandez, Sandra V ^a   Shoshani, Liora ^b   Russo, Irma H ^a   Cereijido, Marcelino ^b   Russo, Jose ^a  

^a FOX CHASE CANCER CENTER   (United States)

^b DEPARTAMENTO DE FÍSICA   (Mexico)

Author keywords

Adhesion junctions; Breast cancer; Estrogen receptor antagonist; Estrogen receptors (ERs); Estrogens; K+ ATPase; Na+; Ouabain; Tight junctions

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM) INHIBITOR; AROMATASE INHIBITOR; CARDIAC GLYCOSIDE; DIGITALIS; DIGITOXIN; DIGOXIN; DIHYDRODIGOXIN; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR; HORMONE; HORMONE RECEPTOR BLOCKING AGENT; OUABAIN; TAMOXIFEN; DIGITALIS GLYCOSIDE; ENZYME INHIBITOR;

ANTINEOPLASTIC ACTIVITY; BREAST CANCER; CANCER CELL; CANCER GROWTH; CELL ADHESION; CELL INTERACTION; CELL MEMBRANE; CELL PROLIFERATION; DISEASE COURSE; DRUG TARGETING; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE SILENCING; HUMAN; ION TRANSPORT; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TARGETING; REVIEW; SIGNAL TRANSDUCTION; ANIMAL; BIOLOGICAL MODEL; BREAST TUMOR; DRUG ANTAGONISM; ENZYMOLOGY; METABOLISM;

ANIMALS; BREAST NEOPLASMS; DIGITALIS GLYCOSIDES; ENZYME INHIBITORS; HUMANS; MODELS, BIOLOGICAL; NA(+)-K(+)-EXCHANGING ATPASE; OUABAIN; RECEPTORS, ESTROGEN;

EID: 33645228747     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10549-005-9053-3     Document Type: Review

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